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Publications 2011

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Adam Antebi

  • Wollam J, Antebi A (2011). Sterol regulation of metabolism, homeostasis, and development. Annu Rev Biochem. Jun 7;80:885-916. Review
  • Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A (2011). The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. Aging Cell. Oct;10(5):879-884. doi: 10.1111/j.1474-9726.2011.00733.x. Epub 2011 Aug 7

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Thomas Benzing

  • Benzing T, Schermer B (2011). Transition zone proteins and cilia dynamics. Nat Genet. Jul 27;43(8):723-4. doi: 10.1038/ng.896
  • Burst V, Benzing T (2011). Dyslipidemia treatment and cardiovascular disease in the renal patient. Curr Pharm Des. 17(9):894-907
  • Dafinger C, Liebau MC, Elsayed SM, Hellenbroich Y, Boltshauser E, Korenke GC, Fabretti F, Janecke AR, Ebermann I, Nürnberg G, Nürnberg P, Zentgraf H, Koerber F, Addicks K, Elsobky E, Benzing T, Schermer B, Bolz HJ (2011). Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. J Clin Invest. Jul 1;121(7). pii: 43639. doi: 10.1172/JCI43639
  • Galldiks N, Burghaus L, Dohmen C, Teschner S, Pollok M, Leebmann J, Frischmuth N, Hollinger P, Nazli N, Fassbender C, Klingel R, Benzing T, Fink GR, Haupt WF (2011). Immunoadsorption in patients with chronic inflammatory demyelinating polyradiculoneuropathy with unsatisfactory response to first-line treatment. Eur Neurol. 66(4):183-9. Epub 2011 Sep 3
  • Habbig S, Bartram MP, Müller RU, Schwarz R, Andriopoulos N, Chen S, Sägmüller JG, Hoehne M, Burst V, Liebau MC, Reinhardt HC, Benzing T, Schermer B (2011). NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol. May 16;193(4):633-42. Epub 2011 May 9
  • Hildebrandt F, Benzing T, Katsanis N (2011). Ciliopathies. N Engl J Med. Apr 21;364(16):1533-43. Review
  • Höhne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Gödel M, Helmstädter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, Benzing T (2011). The BAR Domain Protein PICK1 Regulates Cell Recognition and Morphogenesis by Interacting with Neph Proteins. Mol Cell Biol. Aug;31(16):3241-51. Epub 2011 Jun 20
  • Köttgen M, Benzing T (2011). Strangers on a train: atypical glutamate receptors in the kidney glomerulus. Focus on "Functional NMDA receptors with atypical properties are expressed in podocytes".  Am J Physiol Cell Physiol. Jan;300(1):C9-10. Epub 2010 Nov 10
  • Liebau MC, Höpker K, Müller RU, Schmedding I, Zank S, Schairer B, Fabretti F, Höhne M, Bartram MP, Dafinger C, Hackl M, Burst V, Habbig S, Zentgraf H, Blaukat A, Walz G, Benzing T, Schermer B (2011). Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia. J Biol Chem. Apr 22;286(16):14237-45. Epub 2011 Feb 28
  • Müller RU, Zank S, Fabretti F, Benzing T (2011). Caenorhabditis elegans, a model organism for kidney research: from cilia to mechanosensation and longevity. Curr Opin Nephrol Hypertens. Jul;20(4):400-8
  • Thadhani R, Kisner T, Hagmann H, Bossung V, Noack S, Schaarschmidt W, Jank A, Kribs A, Cornely OA, Kreyssig C, Hemphill L, Rigby AC, Khedkar S, Lindner TH, Mallmann P, Stepan H, Karumanchi SA, Benzing T (2011). Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia. Circulation. Epub 2011 Aug 1

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Susanne Brodesser

  • Brodesser S, Kolter T (2011). Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. J Lipids. 724015. Epub 2010 Dec 5
  • Hench J, Bratić Hench I, Pujol C, Ipsen S, Brodesser S, Mourier A, Tolnay M, Frank S, Trifunović A (2011). A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. PLoS One. 2011;6(12):e28417. doi: 10.1371/journal.pone.0028417. Epub 2011 Dec 5
  • Schneede A, Schmidt CK, Hölttä-Vuori M, Heeren J, Willenborg M, Blanz J, Domanskyy M, Breiden B, Brodesser S, Landgrebe J, Sandhoff K, Ikonen E, Saftig P, Eskelinen EL (2011). Role for LAMP-2 in endosomal cholesterol transport. J Cell Mol Med. Feb;15(2):280-95. doi: 10.1111/j.1582-4934.2009.00973.x

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Hella Brönneke

  • Jordan SD, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC (2011). Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol. 2011 Apr;13(4):434-46. Epub 2011 Mar 27
  • Könner AC, Hess S, Tovar S, Mesaros A, Sánchez-Lasheras C, Evers N, Verhagen LA, Brönneke HS, Kleinridders A, Hampel B, Kloppenburg P, Brüning JC (2011). Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metab. Jun 8;13(6):720-8

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Jens Brüning

  • Chaudhry A, Samstein RM, Treuting P, Liang Y, Pils MC, Heinrich JM, Jack RS, Wunderlich FT, Brüning JC, Müller W, Rudensky AY (2011). Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity. Apr 22;34(4):566-78
  • Hult S, Soylu R, Björklund T, Belgardt BF, Mauer J, Brüning JC, Kirik D, Petersén Å (2011). Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits. Cell Metab. Apr 6;13(4):428-39
  • Jordan SD, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC (2011). Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol. Apr;13(4):434-46. Epub 2011 Mar 27
  • Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, Brüning JC (2011). High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nat Neurosci. Jun 5;14(7):911-8. doi: 10.1038/nn.2847
  • Könner AC, Brüning JC (2011). Toll-like receptors: linking inflammation to metabolism. Trends Endocrinol Metab. Jan;22(1):16-23. Epub 2010 Oct 1. Review
  • Könner AC, Hess S, Tovar S, Mesaros A, Sánchez-Lasheras C, Evers N, Verhagen LA, Brönneke HS, Kleinridders A, Hampel B, Kloppenburg P, Brüning JC (2011). Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metab. Jun 8;13(6):720-8
  • Li P, Cavallero S, Gu Y, Chen TH, Hughes J, Hassan AB, Brüning JC, Pashmforoush M, Sucov HM (2011). IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. May;138(9):1795-805. Epub 2011 Mar 23

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Oliver Cornely

  • Cordonnier C, Rovira M, Maertens J, Cornely OA, Ljungman P, Einsele H (2011). Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants (VOSIFI) study group and the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation (EBMT). Voriconazole as secondary antifungal prophylaxis in stem cell transplant recipients. Haematologica. Feb;96(2):e9-10; author reply e11
  • Cornely OA, Aversa F, Cook P, Jones B, Michallet M, Shea T, Vallejo C (2011). Evaluating the role of prophylaxis in the management of invasive fungal infections in patients with hematologic malignancy. Eur J Haematol. Oct;87(4):289-301. doi: 10.1111/j.1600-0609.2011.01682.x. Epub 2011 Aug 19. Review
  • Cornely OA, Maertens J, Bresnik M, Ebrahimi R, Dellow E, Herbrecht R, Donnelly JP (2011). Efficacy outcomes in a randomised trial of liposomal amphotericin B based on revised EORTC/MSG 2008 definitions of invasive mould disease. Mycoses. Sep;54(5):e449-55. doi: 10.1111/j.1439-0507.2010.01947.x. Epub 2010 Oct 11
  • Cornely OA, Marty FM, Stucker F, Pappas PG, Ullmann AJ (2011). Efficacy and safety of micafungin for treatment of serious Candida infections in patients with or without malignant disease. Mycoses. Nov;54(6):e838-47. doi: 10.1111/j.1439-0507.2011.02045.x. Epub 2011 Jun 13
  • Cornely OA, Pappas PG, Young JA, Maddison P, Ullmann AJ (2011). Accumulated safety data of micafungin in therapy and prophylaxis in fungal diseases. Expert Opin Drug Saf. Mar;10(2):171-83. Epub 2011 Feb 10
  • Hussaini T, Rüping MJ, Farowski F, Vehreschild JJ, Cornely OA (2011). Therapeutic drug monitoring of voriconazole and posaconazole. Pharmacotherapy. Feb;31(2):214-25. Review
  • Maertens J, Marchetti O, Herbrecht R, Cornely OA, Flückiger U, Frêre P, Gachot B, Heinz WJ, Lass-Flörl C, Ribaud P, Thiebaut A, Cordonnier C (2011). Third European Conference on Infections in Leukemia. European guidelines for antifungal management in leukemia and hematopoietic stem cell transplant recipients: summary of the ECIL 3--2009 update. Bone Marrow Transplant. May;46(5):709-18. Epub 2010 Jul 26
  • Ruhnke M, Rickerts V, Cornely OA, Buchheidt D, Glöckner A, Heinz W, Höhl R, Horré R, Karthaus M, Kujath P, Willinger B, Presterl E, Rath P, Ritter J, Glasmacher A, Lass-Flörl C, Groll AH, German Speaking Mycological Society, Paul-Ehrlich-Society for Chemotherapy (2011). Diagnosis and therapy of Candida infections: joint recommendations of the German Speaking Mycological Society and the Paul-Ehrlich-Society for Chemotherapy. Mycoses. 54(4):279-310. doi: 10.1111/j.1439-0507.2011.02040.x. Review
  • Rüping MJ, Keulertz C, Vehreschild JJ, Lövenich H, Söhngen D, Wieland U, Cornely OA (2011). Association of HSV reactivation and pro-inflammatory cytokine levels with the severity of stomatitis after BEAM chemotherapy and autologous SCT. Support Care Cancer. Aug;19(8):1211-6. Epub 2010 Jul 11
  • Rüping MJ, Müller C, Vehreschild JJ, Böhme A, Mousset S, Harnischmacher U, Frommolt P, Wassmer G, Drzisga I, Hallek M, Cornely OA (2011). Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients. Mycoses. May;54(3):230-3. doi: 10.1111/j.1439-0507.2009.01803.x
  • Scheer M, Rabbels J, Neugebauer J, Cornely OA, Drebber U, Zöeller JE (2011). Combined intra- and extracranial cryptococcal infection of a 20-year-old patient in right temporal area. J Oral Maxillofac Surg. Jan;69(1):222-6. Epub 2010 Nov 2
  • Segal BH, Cornely OA, Bromley M (2011). Proceedings from the 4th Advances Against Aspergillosis Conference, February 4-6, 2010, Rome, Italy. Med Mycol. Apr;49 Suppl S5-176. Epub 2010 Nov 26
  • Thadhani R, Kisner T, Hagmann H, Bossung V, Noack S, Schaarschmidt W, Jank A, Kribs A, Cornely OA, Kreyssig C, Hemphill L, Rigby AC, Khedkar S, Lindner TH, Mallmann P, Stepan H, Karumanchi SA, Benzing T (2011). Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia. Circulation. Aug 23;124(8):940-50. Epub 2011 Aug 1
  • Vehreschild MJ, Meissner AM, Cornely OA, Maschmeyer G, Neumann S, von Lilienfeld-Toal M, Karthaus M, Wattad M, Staib P, Hellmich M, Christ H, Vehreschild JJ (2011). Clinically defined chemotherapy-associated bowel syndrome predicts severe complications and death in cancer patients. Haematologica. Dec;96(12):1855-60. Epub 2011 Aug 22

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Martin Denzel

  • Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ, Levine F, Ranscht B (2011). T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion. Islets. 3 (6), 327

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Lukas P. Frenzel

  • Frenzel LP, Claus R, Plume N, Schwamb J, Konermann C, Pallasch CP, Claasen J, Brinker R, Wollnik B, Plass C, Wendtner CM (2011). Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus. Int J Cancer. May 15;128(10):2495-500. doi: 10.1002/ijc.25579
  • Frenzel LP, Patz M, Pallasch CP, Brinker R, Claasen J, Schulz A, Hallek M, Kashkar H, Wendtner CM (2011). Novel X-linked inhibitor of apoptosis inhibiting compound as sensitizer for TRAIL-mediated apoptosis in chronic lymphocytic leukaemia with poor prognosis. Br J Haematol. Jan;152(2):191-200. doi: 10.1111/j.1365-2141.2010.08426.x. Epub 2010 Nov 23
  • Krause G, Patz M, Isaeve P, Wigger M, Baki I, Vondey V, Kerwien S, Kuckertz M, Brinker R, Claasen J, Frenzel LP, Wendtner CM, Heider KH, Hallek M (2011). Action of novel CD37 antibodies on chronic lymphoytic leukemia cells. Leukemia. Sep 2. doi:10.1038/leu.2011.233. Epub 2011 Sep 2
  • Kruse U, Pallasch CP, Bantscheff M, Eberhard D, Frenzel LP, Ghidelli S, Maier SK, Werner T, Wendtner CM, Drewes G (2011). Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells. Leukemia. Jan;25(1):89-100.Epub 2010 Oct 14
  • Patz M, Isaeva P, Forcob N, Müller B, Frenzel LP, Wendtner CM, Klein C, Umana P, Hallek M, Krause G (2011). Comparison of the in vitro effects of the anti-CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells. Br J Haematol. Feb;152(3):295-306. doi: 10.1111/j.1365-2141.2010.08428.x. Epub 2010 Dec 13

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Peter Frommolt

  • Huebner AK, Gandia M, Frommolt P, Maak A, Wicklein EM, Thiele H, Altmüller J, Wagner F, Viñuela A, Aguirre LA, Moreno F, Maier H, Rau I, Giesselmann S, Nürnberg G, Gal A, Nürnberg P, Hübner CA, del Castillo I, Kurth I (2011). Nonsense mutations in SMPX, encoding a protein responsive to physical force, result in X-chromosomal hearing loss. Am J Hum Genet. May 13;88(5):621-7. Epub 2011 May 5
  • Krug KB, Stützer H, Frommolt P, Boecker J, Bovenschulte H, Sendler V, Lackner K (2011). Image quality of digital direct flat-panel mammography versus an indirect small-field CCD technique using a high-contrast phantom. Int J Breast Cancer. 2011:701054. Epub 2010 Oct 17
  • Rüping MJ, Müller C, Vehreschild JJ, Böhme A, Mousset S, Harnischmacher U, Frommolt P, Wassmer G, Drzisga I, Hallek M, Cornely OA (2011). Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients. Mycoses. May;54(3):230-3. doi: 10.1111/j.1439-0507.2009.01803.x

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Michael Hallek

  • Büning H, Bolyard CM, Hallek M, Bartlett JS (2011). Modification and Labeling of AAV Vector Particles. Methods Mol Biol. 2011;807:273-300
  • Cartron G, Trappe RU, Solal-Céligny P, Hallek M (2011). Interindividual variability of response to rituximab: from biological origins to individualized therapies. Clin Cancer Res. Jan 1;17(1):19-30. Review
  • Chemnitz JM, von Lilienfeld-Toal M, Holtick U, Theurich S, Shimabukuro-Vornhagen A, Krause A, Brossart P, Hallek M, Scheid C (2011). Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia. Ann Hematol.  2012 Jan;91(1):47-55. doi: 10.1007/s00277-011-1253-9. Epub 2011 May 17
  • Cramer P, Hallek M (2011). Prognostic factors in chronic lymphocytic leukemia-what do we need to know? Nat Rev Clin Oncol. Jan;8(1):38-47. Epub 2010 Oct 19. Review
  • Eichhorst BF, Fischer K, Fink AM, Elter T, Wendtner CM, Goede V, Bergmann M, Stilgenbauer S, Hopfinger G, Ritgen M, Bahlo J, Busch R, Hallek M (2011). German CLL Study Group (GCLLSG). Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis. Blood. Feb 10;117(6):1817-21. Epub 2010 Dec 7
  • Elter T, Hallek M, Montillo M (2011). Alemtuzumab: what is the secret to safe therapy? Clin Adv Hematol Oncol. May;9(5):364-73. Review
  • Elter T, Gercheva-Kyuchukova L, Pylylpenko H, Robak T, Jaksic B, Rekhtman G, Kyrcz-Krzemień S, Vatutin M, Wu J, Sirard C, Hallek M, Engert A (2011). Fludarabine plus alemtuzumab versus fludarabine alone in patients with previously treated chronic lymphocytic leukaemia: a randomised phase 3 trial. Lancet Oncol. Oct 10. Epub 2011 Oct 10
  • Fischer K, Cramer P, Busch R, Stilgenbauer S, Bahlo J, Schweighofer CD, Böttcher S, Staib P, Kiehl M, Eckart MJ, Kranz G, Goede V, Elter T, Bühler A, Winkler D, Kneba M, Döhner H, Eichhorst BF, Hallek M, Wendtner CM (2011). Bendamustine combined with rituximab in patients with relapsed and/or refractory chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol. Sep 10; 29(26):3559-66. Epub 2011 Aug 15
  • Frenzel LP, Patz M, Pallasch CP, Brinker R, Claasen J, Schulz A, Hallek M, Kashkar H, Wendtner CM (2011). Novel X-linked inhibitor of apoptosis inhibiting compound as sensitizer for TRAIL-mediated apoptosis in chronic lymphocytic leukaemia with poor prognosis. Br J Haematol. Jan;152(2):191-200. doi: 10.1111/j.1365-2141.2010.08426.x. Epub 2010 Nov 23
  • Gaertner J, Wolf J, Hallek M, Glossmann JP, Voltz R (2011). Standardizing integration of palliative care into comprehensive cancer therapy--a disease specific approach. Support Care Cancer. Jul;19(7):1037-43. Epub 2011 Mar 24
  • Gaertner J, Wolf J, Frechen S, Klein U, Scheicht D, Hellmich M, Toepelt K, Glossmann JP, Ostgathe C, Hallek M, Voltz R (2011). Recommending early integration of palliative care - does it work? Support Care Cancer. 2012 Mar;20(3):507-13. doi: 10.1007/s00520-011-1111-2. Epub 2011 Feb 19
  • Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA (2011). Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells. Mol Med. 17(7-8):619-27. doi: 10.2119/molmed.2010.00210. Epub 2011 Apr 14
  • Goede V, Hallek M (2011). Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: considerations in the elderly. Drugs Aging. Mar 1;28(3):163-76. doi: 10.2165/11587650-000000000-00000. Review
  • Hallek M, Pflug N (2011). State of the art treatment of chronic lymphocytic leukaemia. Blood Rev. Jan;25(1):1-9. Epub 2010 Nov 20. Review
  • Hehlmann R, Grimwade D, Simonsson B, Apperley J, Baccarani M, Barbui T, Barosi G, Bassan R, Béné MC, Berger U, Büchner T, Burnett A, Cross NC, de Witte TJ, Döhner H, Dombret H, Einsele H, Engelich G, Foà R, Fonatsch C, Gökbuget N, Gluckman E, Gratwohl A, Guilhot F, Haferlach C, Haferlach T, Hallek M, Hasford J, Hochhaus A, Hoelzer D, Kiladjian JJ, Labar B, Ljungman P, Mansmann U, Niederwieser D, Ossenkoppele G, Ribera JM, Rieder H, Serve H, Schrotz-King P, Sanz MA, Saussele S (2011). European LeukemiaNet. The European LeukemiaNet: achievements and perspectives. Haematologica. Jan;96(1):156-62. Epub 2010 Nov 3
  • Hösel M, Broxtermann M, Janicki H, Esser K, Arzberger S, Hartmann P, Gillen S, Kleeff J, Stabenow D, Odenthal M, Knolle P, Hallek M, Protzer U, Büning H (2011). TLR2-mediated innate immune response in human non-parenchymal liver cells towards adeno-associated viral (AAV) vectors. Hepatology. Aug 24. doi: 10.1002/hep.24625
  • Koehler P, Schmidt P, Hombach AA, Hallek M, Abken H (2011). Engineered T cells for the adoptive therapy of B-cell chronic lymphocytic leukaemia. Adv Hematol. 2012:595060. Epub 2011 Aug 8
  • Krause G, Hallek M (2011). On the assessment of dasatinib-induced autophagy in CLL. Leuk Res. Jan;35(1):137-8. Epub 2010 Oct 14
  • Krings Rocha C, Wendtner CM, Hallek M, Kreuzer KA (2011). Conventional cytogenetics in chronic lymphocytic leukemia (CLL). Leuk Res. Mar;35(3):e25. Epub 2010 Nov 11
  • Lilienthal N, Prinz C, Peer-Zada AA, Doering M, Ba LA, Hallek M, Jacob C, Herling M (2011). Targeting the disturbed redox equilibrium in chronic lymphocytic leukemia by novel reactive oxygen species-catalytic 'sensor/effector' compounds. Leuk Lymphoma. Jul; 52(7):1407-11. Epub 2011 Mar 29
  • Michallet M, Dreger P, Sutton L, Brand R, Richards S, van Os M, Sobh M, Choquet S, Corront B, Dearden C, Gratwohl A, Herr W, Catovsky D, Hallek M, de Witte T, Niederwieser D, Leporrier M, Milligan D (2011) EBMT Chronic Leukemia Working Party. Autologous hematopoietic stem cell transplantation in chronic lymphocytic leukemia: results of European intergroup randomized trial comparing autografting versus observation. Blood. Feb 3;117(5):1516-21. Epub 2010 Nov 24
  • Patz M, Isaeva P, Forcob N, Müller B, Frenzel LP, Wendtner CM, Klein C, Umana P, Hallek M, Krause G (2011). Comparison of the in vitro effects of the anti-CD20 antibodies rituximab and GA101 on chronic lymphocytic leukaemia cells. Br J Haematol. Feb;152(3):295-306. doi: 10.1111/j.1365-2141.2010.08428.x. Epub 2010 Dec 13
  • Razavi R, Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA (2011). Nitric oxide-donating acetylsalicylic acid induces apoptosis in chronic lymphocytic leukemia cells and shows strong antitumor efficacy in vivo. Clin Cancer Res. Jan 15;17(2):286-93. Epub 2010 Nov 19
  • Rocha CK, Praulich I, Gehrke I, Hallek M, Kreuzer KA (2011). A rare case of t(11;22) in a mantle cell lymphoma like B-cell neoplasia resulting in a fusion of IGL and CCNDcase report. Mol Cytogenet. Apr 1;4(1):8
  • Rüping MJ, Müller C, Vehreschild JJ, Böhme A, Mousset S, Harnischmacher U, Frommolt P, Wassmer G, Drzisga I, Hallek M, Cornely OA (2011). Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients. Mycoses. May;54(3):230-3. doi: 10.1111/j.1439-0507.2009.01803.x
  • Stahnke S, Lux K, Uhrig S, Kreppel F, Hösel M, Coutelle O, Ogris M, Hallek M, Büning H (2011). Intrinsic phospholipase A2 activity of adeno-associated virus is involved in endosomal escape of incoming particles. Virology. Jan 5;409(1):77-83. Epub 2010 Oct 25
  • Tichelli A, Schrezenmeier H, Socié G, Marsh J, Bacigalupo A, Dührsen U, Franzke A, Hallek M, Thiel E, Wilhelm M, Höchsmann B, Barrois A, Champion K, Passweg JR (2011). A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation. Blood. Apr 28;117(17):4434-41. Epub 2011 Jan 13
  • Uhrmacher S, Schmidt C, Erdfelder F, Poll-Wolbeck SJ, Gehrke I, Hallek M, Kreuzer KA (2011). Use of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) as a diagnostic tool in chronic lymphocytic leukemia (CLL). Leuk Res. Oct; 35(10):1360-6. doi: 10.1016/j.leukres.2011.04.006. Epub 2011 Apr 30
  • Wendtner CM, Hillmen P, Mahadevan D, Bühler A, Uharek L, Coutré S, Frankfurt O, Bloor A, Bosch F, Furman RR, Kimby E, Gribben JG, Gobbi M, Dreisbach L, Hurd DD, Sekeres MA, Ferrajoli A, Shah S, Zhang J, Moutouh-de Parseval L, Hallek M, Heerema NA, Stilgenbauer S, Chanan-Khan AA (2011). Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia. Leuk Lymphoma. Aug 31. Epub 2011 Nov 15
  • Zander T, Scheffler M, Nogova L, Kobe C, Engel-Riedel W, Hellmich M, Papachristou I, Toepelt K, Draube A, Heukamp L, Buettner R, Ko YD, Ullrich RT, Smit E, Boellaard R, Lammertsma AA, Hallek M, Jacobs AH, Schlesinger A, Schulte K, Querings S, Stoelben E, Neumaier B, Thomas RK, Dietlein M, Wolf J (2011). Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F] fluorodeoxyglucose and [(18)F] luorothymidine positron emission tomography. J Clin Oncol. May 1;29(13):1701-8. Epub 2011 Mar 21

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Matthias Hammerschmidt

  • Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nürnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Müller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C (2011). Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet. Feb 11;88(2):127-37. Epub 2011 Jan 20
  • Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, Xu X, Hammerschmidt M, Ekker SC (2011). In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nat Methods. Jun;8(6):506-15. Epub 2011 May 8
  • Feitosa NM, Richardson R, Bloch W, Hammerschmidt M (2011). Basement membrane diseases in zebrafish. Methods Cell Biol. 105:191-222
  • Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG (2011). BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin. PLoS One. Jan 21;6(1):e14553
  • Laue K, Pogoda HM, Daniel PB, van Haeringen A, Alanay Y, von Ameln S, Rachwalski M, Morgan T, Gray MJ, Breuning MH, Sawyer GM, Sutherland-Smith AJ, Nikkels PG, Kubisch C, Bloch W, Wollnik B, Hammerschmidt M, Robertson SP (2011). Craniosynostosis and Multiple Skeletal Anomalies in Humans and Zebrafish Result from a Defect in the Localized Degradation of Retinoic Acid. Am J Hum Genet. 2011 Nov 11;89(5):595-606. doi: 10.1016/j.ajhg.2011.09.015. Epub 2011 Oct 20
  • Löhr H, Hammerschmidt M (2011). Zebrafish in endocrine systems: recent advances and implications for human disease. Annu Rev Physiol. Mar 17;73:183-211. Review

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Hans Christian Hennies

  • Arweiler-Harbeck D, Horsthemke B, Jahnke K, Hennies HC (2011). Genetic Aspects of Familial Ménière's Disease. Otol Neurotol. Jun;32(4):695-700
  • Blaydon DC, Nitoiu D, Eckl KM, Cabral RM, Bland P, Hausser I, van Heel DA, Rajpopat S, Fischer J, Oji V, Zvulunov A, Traupe H, Hennies HC, Kelsell DP (2011). Mutations in CSTA, encoding Cystatin A, underlie exfoliative ichthyosis and reveal a role for this protease inhibitor in cell-cell adhesion. Am J Hum Genet. Oct 7;89(4):564-71. doi: 10.1016/j.ajhg.2011.09.001. Epub 2011 Sep 22
  • Eckl KM, Alef T, Torres S, Hennies HC (2011). Full-Thickness Human Skin Models for Congenital Ichthyosis and Related Keratinization Disorders. J Invest Dermatol. Epub 2011 May 19
  • Forstbauer LM, Brockschmidt FF, Moskvina V, Herold C, Redler S, Herzog A, Hillmer AM, Meesters C, Heilmann S, Albert F, Alblas M, Hanneken S, Eigelshoven S, Giehl KA, Jagielska D, Blume-Peytavi U, Bartels NG, Kuhn J, Hennies HC, Goebeler M, Jung A, Peitsch WK, Kortüm AK, Moll I, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Kirov G, Becker T, Nöthen MM, Betz RC (2011). Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata. Eur J Hum Genet. Oct 26. doi: 10.1038/ejhg.2011.185. Epub 2011 Oct 26
  • Nousbeck J, Ishida-Yamamoto A, Bidder M, Fuchs D, Eckl K, Hennies HC, Sagiv N, Gat A, Gini M, Filip I, Matz H, Goldberg I, Enk CD, Sarig O, Meilik B, Aberdam D, Gilhar A, Sprecher E (2011). IGFBP7 as a Potential Therapeutic Target in Psoriasis. J Invest Dermatol. Aug;131(8):1767-70. doi: 10.1038/jid.2011.108. Epub 2011 May 12
  • Seifert W, Kühnisch J, Maritzen T, Horn D, Haucke V, Hennies HC (2011). Cohen Syndrome-associated Protein, COH1, Is a Novel, Giant Golgi Matrix Protein Required for Golgi Integrity. J Biol Chem. Oct 28;286(43):37665-75. Epub 2011 Aug 24

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Marco Herling

  • Lilienthal N, Prinz C, Peer-Zada AA, Doering M, Ba LA, Hallek M, Jacob C, Herling M (2011). Targeting the disturbed redox equilibrium in chronic lymphocytic leukemia by novel reactive oxygen species-catalytic 'sensor/effector' compounds. Leuk Lymphoma. Jul;52(7):1407-11. Epub 2011 Mar 29

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Thorsten Hoppe

  • Acs K, Luijsterburg MS, Ackermann L, Salomons FA, Hoppe T, Dantuma NP (2011). The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat Struct Mol Biol. Nov 27;18(12):1345-50
  • Franz A, Orth M, Pirson PA, Sonneville R, Blow JJ, Gartner A, Stemmann O, Hoppe T (2011). CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication. Mol Cell. 44, 85-96
  • Hoppe T (2011). Too salty for worms: hypertonic stress challenges proteostasis networks. Focus on "Hypertonic stress induces rapid and widespread protein damage in C. elegans". Am J Physiol Cell Physiol. Sep;301(3):C555-6. Epub 2011 Jun 29
  • Kuhlbrodt K, Janiesch PC, Kevei É, Segref A, Barikbin R, Hoppe T (2011). The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis. Nat Cell Biol. Mar;13(3):273-81. Epub 2011 Feb 13
  • Segref A, Torres S, Hoppe T (2011). A screenable in vivo assay to study proteostasis networks in Caenorhabditis elegans. Genetics. Apr;187(4):1235-40. Epub 2011 Feb 1

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Sandra Iden

  • Iden S, Misselwitz S, Peddibhotla S, Tuncay H, Rehder D, Gerke V, Robenek H, Suzuki A, Ebnet K (2011). Atypical PKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J Cell Biol. In Press

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Hamid Kashkar

  • Frenzel LP, Patz M, Pallasch CP, Brinker R, Claasen J, Schulz A, Hallek M, Kashkar H, Wendtner CM (2011). Novel X-linked inhibitor of apoptosis inhibiting compound as sensitizer for TRAIL-mediated apoptosis in chronic lymphocytic leukaemia with poor prognosis. Br J Haematol. Jan;152(2):191-200. doi: 10.1111/j.1365-2141.2010.08426.x. Epub 2010 Nov 23
  • Jordan SD, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC (2011). Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol. Apr;13(4):434-46. Epub 2011 Mar 27

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Peter Kloppenburg

  • Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, Brüning JC (2011). High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nat Neurosci. Jun 5;14(7):911-8. doi: 10.1038/nn.2847
  • Könner AC, Hess S, Tovar S, Mesaros A, Sánchez-Lasheras C, Evers N, Verhagen LA, Brönneke HS, Kleinridders A, Hampel B, Kloppenburg P, Brüning JC (2011). Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metab. Jun 8;13(6):720-8
  • Neupert S, Fusca D, Schachtner J, Kloppenburg P, Predel R (2011). Towards a Single-cell-based analysis of neuropeptide expression in Periplaneta americana antennal lobe neurons. J Comp Neurol. Aug 8. doi: 10.1002/cne.22745 
  • Oliveira EE, Schleicher S, Büschges A, Schmidt J, Kloppenburg P, Salgado VL (2011). Desensitization of nicotinic acetylcholine receptors in central nervous system neurons of the stick insect (Carausius morosus) by imidacloprid and sulfoximine insecticides. Insect Biochem Mol Biol. Nov;41(11):872-80. Epub 2011 Aug 23

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Jan-Wilhelm Kornfeld

  • Kornfeld JW, Meder S, Wohlberg M, Friedrich RE, Rau T, Riethdorf L, Löning T, Pantel K, Riethdorf S (2011). Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression. Br J Cancer. Jan 4;104(1):138-45
  • Mueller KM, Kornfeld JW, Friedbichler K, Blaas L, Egger G, Esterbauer H, Hasselblatt P, Schlederer M, Haindl S, Wagner KU, Engblom D, Haemmerle G, Kratky D, Sexl V, Kenner L, Kozlov AV, Terracciano L, Zechner R, Schuetz G, Casanova E, Pospisilik JA, Heim MH, Moriggl R (2011). Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. Hepatology. Oct;54(4):1398-409

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    Thomas Krieg

    • Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JF, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R, Wiesner RJ (2011). The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells. Sep;29(9):1459-68. doi: 10.1002/stem.695
    • Bartenwerffer W von, Has C, Arin MJ, Tantcheva-Poór I, Kreuter A, Kremer K, Arshah T, Hoffmann M, Eming SA, Kohlhase J, Krieg T, Bruckner-Tuderman L, Hartmann K (2011). Mild recessive dystrophic epidermolysis bullosa associated with two compound heterozygous COL7A1 mutations. Eur J Dermatol. Mar-Apr;21(2):170-2
    • Dudeck A, Dudeck J, Scholten J, Petzold A, Surianarayanan S, Köhler A, Peschke K, Vöhringer D, Waskow C, Krieg T, Müller W, Waisman A, Hartmann K, Gunzer M, Roers A (2011). Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity. Jun 24;34(6):973-84
    • Galluccio F, Walker UA, Nihtyanova S, Moinzadeh P, Hunzelmann N, Krieg T, Steen V, Baron M, Sampaio-Barros P, Kayser C, Nash P, Denton CP, Tyndall A, Müller-Ladner U, Matucci-Cerinic M (2011). Registries in systemic sclerosis: a worldwide experience. Rheumatology. Jan;50(1):60-8. Review
    • Gerbaulet A, Wickenhauser C, Scholten J, Peschke K, Drube S, Horny HP, Kamradt T, Naumann R, Müller W, Krieg T, Waskow C, Hartmann K, Roers A (2011). Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit. Blood. Feb 10;117(6):2012-21. Epub 2010 Dec 9
    • Grube K, Rüdebusch J, Xu Z, Böckenholt T, Methner C, Müller T, Cuello F, Zimmermann K, Yang X, Felix SB, Cohen MV, Downey JM, Krieg T (2011). Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes. Basic Res Cardiol. May;106(3):385-96. Epub 2011 Jan 19
    • Hoffmann DC, Textoris C, Oehme F, Klaassen T, Goppelt A, Römer A, Fugmann B, Davidson JM, Werner S, Krieg T, Eming SA (2011). Pivotal role for alpha1-antichymotrypsin in skin repair. J Biol Chem. Aug 19;286(33):28889-901. Epub 2011 Jun 21
    • Hovest MG, Krieg T, Herrmann G (2011). Differential roles for Chk1 and FANCD2 in ATR-mediated signalling for psoralen photoactivation-induced senescence. Exp Dermatol. Nov;20(11):883-9. doi: 10.1111/j.1600-0625.2011.01365.x
    • Krieg T, Aumailley M (2011). The extracellular matrix of the dermis: flexible structures with dynamic functions. Exp Dermatol. Aug;20(8):689-95. doi: 10.1111/j.1600-0625.2011.01313.x. Epub 2011 May 25. Review
    • Methner C, Krieg T (2011). A2b adenosine receptors in cardioprotection: timing is everything. J Mol Cell Cardiol. Mar;50(3):582-3. Epub 2010 Nov 2
    • Mierau R, Moinzadeh P, Riemekasten G, Melchers I, Meurer M, Reichenberger F, Buslau M, Worm M, Blank N, Hein R, Müller-Ladner U, Kuhn A, Sunderkötter C, Juche A, Pfeiffer C, Fiehn C, Sticherling M, Lehmann P, Stadler R, Schulze-Lohoff E, Seitz C, Foeldvari I, Krieg T, Genth E, Hunzelmann N (2011). Frequency of disease-associated and other nuclear autoantibodies in patients of the German Network for Systemic Scleroderma: correlation with characteristic clinical features. Arthritis Res Ther. 13(5):R172. Epub 2011 Oct 21
    • Moinzadeh P, Krieg T, Hellmich M, Brinckmann J, Neumann E, Müller-Ladner U, Kreuter A, Dumitrescu D, Rosenkranz S, Hunzelmann N (2011). Elevated MMP-7 levels in patients with systemic sclerosis: correlation with pulmonary involvement. Exp Dermatol. Sep;20(9):770-3. doi: 10.1111/j.1600-0625.2011.01321.x. Epub 2011 Jun 26
    • Moinzadeh P, Hunzelmann N, Krieg T (2011). Combination therapy with an endothelin-1 receptor antagonist (bosentan) and a phosphodiesterase V inhibitor (sildenafil) for the management of severe digital ulcerations in systemic sclerosis. J Am Acad Dermatol. Sep;65(3):e102-4
    • Veit G, Zwolanek D, Eckes B, Niland S, Käpylä J, Zweers MC, Ishada-Yamamoto A, Krieg T, Heino J, Eble JA, Koch M (2011). Collagen XXIII, novel ligand for integrin alpha2beta1 in the epidermis. J Biol Chem. Aug 5;286(31):27804-13. Epub 2011 Jun 7
    • Walker KM, Pope J, Scleroderma Clinical Trias Consortium, Canadian Scleroderma Research Group (2011).  Expert agreement on EULAR/EUSTAR recommendations for the management of systemic sclerosis. J Rheumatol. Jul;38(7):1326-8. Epub 2011 Apr 1
    • Zhang Z, Chometon G, Wen T, Qu H, Mauch C, Krieg T, Aumailley M (2011). Migration of epithelial cells on laminins: RhoA antagonizes directionally persistent migration. Eur J Cell Biol. Jan;90(1):1-12. Epub 2010 Oct 23

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    Martin Krönke

    • Bielig H, Velder J, Saiai A, Menning M, Meemboor S, Kalka-Moll W, Krönke M, Schmalz HG, Kufer TA (2011). Anti-inflammatory arene--chromium complexes acting as specific inhibitors of NOD2 signalling. Chem Med Chem. 2010 Dec 3;5(12):2065-71
    • Schnitger AK, Machova A, Mueller RU, Androulidaki A, Schermer B, Pasparakis M, Krönke M, Papadopoulou N (2011). Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response. PLoS One. 2011;6(11):e27435. Epub 2011 Nov 17

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    Wilhelm Krone

    • Berthold HK, Laudes M, Krone W, Gouni-Berthold I (2011). Association between the interleukin-6 promoter polymorphism -174G/C and serum lipoprotein(a) concentrations in humans. PLoS One. 6(9):e24719. Epub 2011 Sep 14
    • Berthold HK, Bestehorn KP, Jannowitz C, Krone W, Gouni-Berthold I (2011). Disease management programs in type 2 diabetes: quality of care. Am J Manag Care. Jun;17(6):393-403
    • Gouni-Berthold I, Schulte DM, Krone W, Lapointe JF, Lemieux P, Predel HG, Berthold HK (2011). The whey fermentation product malleable protein matrix decreases TAG concentrations in patients with the metabolic syndrome: a randomised placebo-controlled trial. Br J Nutr. 2012 Jun;107(11):1694-706. doi: 10.1017/S0007114511004843
    • Stöhr O, Hahn J, Moll L, Leeser U, Freude S, Bernard C, Schilbach K, Markl A, Udelhoven M, Krone W, Schubert M (2011). Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells. Biochim Biophys Acta. May;1812(5):573-80. Epub 2011 Feb 24
    • Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M (2011). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. Age. (Dordr.) 2013 Feb;35(1):83-101. doi: 10.1007/s11357-011-9333-2. Epub 2011 Nov 6

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    Christian Kubisch

    • Ahmad A, Daud S, Kakar N, Nürnberg G, Nürnberg P, Babar ME, Thoenes M, Kubisch C, Ahmad J, Bolz HJ (2011). Identification of a novel LCA5 mutation in a Pakistani family with Leber congenital amaurosis and cataracts. Mol Vis. 17:1940-5. Epub 2011 Jul 16
    • Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS, Nyholt DR, Dimas AS, Freilinger T, Müller-Myhsok B, Artto V, Inouye M, Alakurtti K, Kaunisto MA, Hämäläinen E, de Vries B, Stam AH, Weller CM, Heinze A, Heinze-Kuhn K, Goebel I, Borck G, Göbel H, Steinberg S, Wolf C, Björnsson A, Gudmundsson G, Kirchmann M, Hauge A, Werge T, Schoenen J, Eriksson JG, Hagen K, Stovner L, Wichmann HE, Meitinger T, Alexander M, Moebus S, Schreiber S, Aulchenko YS, Breteler MM, Uitterlinden AG, Hofman A, van Duijn CM, Tikka-Kleemola P, Vepsäläinen S, Lucae S, Tozzi F, Muglia P, Barrett J, Kaprio J, Färkkilä M, Peltonen L, Stefansson K, Zwart JA, Ferrari MD, Olesen J, Daly M, Wessman M, van den Maagdenberg AM, Dichgans M, Kubisch C, Dermitzakis ET, Frants RR, Palotie A (2010). International Headache Genetics Consortium. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat Genet. Oct;42(10):869-73. Epub 2010 Aug 29
    • Borck G, Kakar N, Hoch J, Friedrich K, Freudenberg J, Nürnberg G, Yilmaz R, Daud S, Baloch DM, Nürnberg P, Oldenburg J, Ahmad J, Kubisch C (2011). An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group. Hum Genet. 2012 Feb;131(2):209-16. doi: 10.1007/s00439-011-1062-1. Epub 2011 Jul 15
    • Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nürnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Müller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C (2011). Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet. Feb 11;88(2):127-37. Epub 2011 Jan 20
    • Borck G, Wunram H, Steiert A, Volk AE, Körber F, Roters S, Herkenrath P, Wollnik B, Morris-Rosendahl DJ, Kubisch C (2011). A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome. Hum Genet. Jan;129(1):45-50. Epub 2010 Oct 22
    • Chasman DI, Schürks M, Anttila V, de Vries B, Schminke U, Launer LJ, Terwindt GM, van den Maagdenberg AM, Fendrich K, Völzke H, Ernst F, Griffiths LR, Buring JE, Kallela M, Freilinger T, Kubisch C, Ridker PM, Palotie A, Ferrari MD, Hoffmann W, Zee RY, Kurth T (2011). Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat Genet. Jun 12;43(7):695-8. doi: 10.1038/ng.856
    • Hisama FM, Lessel D, Leistritz D, Friedrich K, McBride KL, Pastore MT, Gottesman GS, Saha B, Martin GM, Kubisch C, Oshima J (2011). Coronary artery disease in a Werner syndrome-like form of progeria characterized by low levels of progerin, a splice variant of lamin A. Am J Med Genet A. Dec;155A(12):3002-6. doi: 10.1002/ajmg.a.34336. Epub 2011 Nov 7
    • Laue K, Pogoda HM, Daniel PB, van Haeringen A, Alanay Y, von Ameln S, Rachwalski M, Morgan T, Gray MJ, Breuning MH, Sawyer GM, Sutherland-Smith AJ, Nikkels PG, Kubisch C, Bloch W, Wollnik B, Hammerschmidt M, Robertson SP (2011). Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. Am J Hum Genet. Nov 11;89(5):595-606. doi: 10.1016/j.ajhg.2011.09.015. Epub 2011 Oct 20
    • Park JS, Mehta P, Cooper AA, Veivers D, Heimbach A, Stiller B, Kubisch C, Fung VS, Krainc D, Mackay-Sim A, Sue CM (2011). Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism. Hum Mutat. Aug;32(8):956-64. doi: 10.1002/humu.21527. Epub 2011 Jul 12
    • Ugolino J, Fang S, Kubisch C, Monteiro MJ (2011). Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death. Hum Mol Genet. Sep 15;20(18):3565-77. Epub 2011 Jun 10
    • Volk AE, Carter O, Fricke J, Herkenrath P, Poggenborg J, Borck G, Demant AW, Ivo R, Eysel P, Kubisch C, Neugebauer A (2011). Horizontal gaze palsy with progressive scoliosis: three novel ROBO3 mutations and descriptions of the phenotypes of four patients. Mol Vis. 17:1978-86. Epub 2011 Jul 20

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    Leo Kurian

    • Kurian L, Palanimurugan R, Gödderz D, Dohmen RJ (2011). Polyamine sensing by nascent ODC antizyme stimulates decoding of its mRNA. Nature. Sep 7;477(7365):490-4
    • Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC (2011). Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature. Apr 14;472(7342):221-5

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    Thomas Langer

    • Alikhani N, Berglund AK, Engmann T, Spanning E, Vögtle FN, Pavlov P, Meisinger C, Langer T, Glaser E (2011). Targeting capacity and conservation of PreP homologues localization in mitochondria of different species. J Mol Biol. 410, 400-410
    • Anton F, Fres JM, Schauss A, Pinson B, Praefcke GJK, Langer T, Esco­bar-Henriques M (2011). Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci. 124, 1126-1135
    • Baker MJ, Tatsuta T, Langer T (2011). Quality control of mitochondrial proteosta­sis. CSH Perspect. Biol. 3. Cold Spring Harbor Laboratory Press
    • Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JFG, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R, Wiesner, RJ (2011). The mitochondrial electron transport chain is dis­pensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells. 29, 1459-1468
    • Bonn F, Tatsuta T, Petrungaro C, Riemer J, Langer T (2011). Presequence-dependent folding ensures MRPL32 processing by the m-AAA protease in mitochon­dria. EMBO J. 30, 2545-2556
    • Gerdes F, Tatsuta T, Langer T (2011). Mitochondrial AAA proteases: Towards a molecular understanding of membrane-bound proteolytic machines. Biochim Bio­phys. Acta 1823, 49-55
        • Lee S, Augustin S, Tatsuta T, Gerdes F, Langer T, Tsai FT (2011). Elec­tron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease. J Biol Chem. 286, 4404-4411
        • Morimoto RI, Driessen AJ, Hegde RS, Langer T (2011). The life of proteins: the good, the mostly good and the ugly. Nat Struct Mol Biol. 18, 1-4
        • Osman C, Voelker DR, Langer T (2011). Making heads or tails of phospholip­ids in mitochondria. J Cell Biol. 192, 7-16
        • Pierson TM, Adams D, Bonn F, Martinelli P, Cherukuri PF, Teer JK, Hansen NF, Cruz P, Mullikin JC for the NISC Comparative Sequencing Program, Blakesley RW, Golas G, Kwan J, Sandler A, Fuentes Fajardo K, Markello T, Tifft C, Blackstone C, Rugarli EI, Langer T, Gahl WA, Toro C (2011). Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxie-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genet. 7: e1002325
        • Potting C, Wilmes C, Engmann T, Osman C, Langer T (2011). Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. EMBO J. 29, 2888-2898

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        Nils-Göran Larsson

        • Ameur A, Stewart JB, Freyer C, Hagström E, Ingman M, Larsson NG, Gyllensten U (2011). Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins. PLoS Genet. Mar;7(3):e1002028. Epub 2011 Mar 24
        • Andersson DC, Fauconnier J, Park CB, Zhang SJ, Thireau J, Ivarsson N, Larsson NG (2011). Enhanced cardiomyocyte Ca(2+) cycling precedes terminal AV-block in mitochondrial cardiomyopathy Mterf3 KO mice. Antioxid Redox Signal. Nov 1;15(9):2455-64. Epub 2011 May 25
        • Atanassova N, Fusté JM, Wanrooij S, Macao B, Goffart S, Bäckström S, Farge G, Khvorostov I, Larsson NG, Spelbrink JN, Falkenberg M (2011). Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia. Hum Mol Genet. Mar 15;20(6):1212-23. Epub 2011 Jan 12
        • Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JF, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R (2011). The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells. Sep;29(9):1459-68. doi: 10.1002/stem.695
        • Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG (2011). The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet. Oct;7(10):e1002324. Epub 2011 Oct 13
        • Cámara Y, Asin-Cayuela J, Park CB, Metodiev MD, Shi Y, Ruzzenente B, Kukat C, Habermann B, Wibom R, Hultenby K, Franz T, Erdjument-Bromage H, Tempst P, Hallberg BM, Gustafsson CM, Larsson NG (2011). MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome. Cell Metab. May 4;13(5):527-39
        • Good CH, Hoffman AF, Hoffer BJ, Chefer VI, Shippenberg TS, Bäckman CM, Larsson NG, Olson L, Gellhaar S, Galter D, Lupica CR (2011). Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease. FASEB J. Apr;25(4):1333-44. Epub 2011 Jan 13
        • Hallberg BM, Larsson NG (2011). TFAM forces mtDNA to make a U-turn. Nat Struct Mol Biol. Nov 4;18(11):1179-81. doi: 10.1038/nsmb.2167
        • Koeck T, Olsson AH, Nitert MD, Sharoyko VV, Ladenvall C, Kotova O, Reiling E, Rönn T, Parikh H, Taneera J, Eriksson JG, Metodiev MD, Larsson NG, Balhuizen A, Luthman H, Stančáková A, Kuusisto J, Laakso M, Poulsen P, Vaag A, Groop L, Lyssenko V, Mulder H, Ling C (2011). A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes. Cell Metab. Jan 5;13(1):80-91
        • Kukat C, Wurm CA, Spåhr H, Falkenberg M, Larsson NG (2011). Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. Proc Natl Acad Sci U S A. Aug 16;108(33):13534-9. Epub 2011 Aug 1
        • Mourier A, Larsson NG (2011). Tracing the trail of protons through complex I of the mitochondrial respiratory chain. PLoS Biol. Aug;9(8):e1001129. Epub 2011 Aug 23
        • Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC (2011). Unraveling the biological roles of reactive oxygen species. Cell Metab. Apr 6;13(4):361-6
        • Park CB, Larsson NG (2011). Mitochondrial DNA mutations in disease and aging. J Cell Biol. May 30;193(5):809-18. Epub 2011 May 23. Review
        • Ruzzenente B, Metodiev MD, Wredenberg A, Bratic A, Park CB, Cámara Y, Milenkovic D, Zickermann V, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Brandt U, Stewart JB, Gustafsson CM, Larsson NG (2011). LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs. EMBO J. Nov 1;31(2):443-56. doi: 10.1038/emboj.2011.392
        • Sterky FH, Lee S, Wibom R, Olson L, Larsson NG (2011). Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc Natl Acad Sci U S A. Aug 2;108(31):12937-42. Epub 2011 Jul 18

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        Ivan Matic

        • Bruderer R, Tatham MH, Plechanovova A, Matic I, Garg AK, Hay RT (2011). Purification and identification of endogenous polySUMO conjugates. EMBO reports. 12, (2), 142-8
        • Matic I, Jaffray E G, Oxenham SK, Groves MJ, Barratt CL, Tauro S, Stanley-Wall NR, Hay RT (2011). Absolute SILAC-compatible expression strain allows Sumo-2 copy number determination in clinical samples. Journal of proteome research. 10, (10), 4869-75
        • Tatham MH, Matic I, Mann M, Hay RT (2011). Comparative proteomic analysis identifies a role for SUMO in protein quality control. Science signaling. 4, (178), rs4

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        Pierluigi Nicotera

        • Agostini M, Tucci P, Killick R, Candi E, Sayan BS, Rivetti di Val Cervo P, Nicotera P, McKeon F, Knight RA, Mak TW, Melino G (2011). Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A. Dec 27;108(52):21093-8. Epub 2011 Dec 12
        • Bano D, Agostini M, Melino G, Nicotera P (2011). Ageing, neuronal connectivity and brain disorders: an unsolved ripple effect. Mol Neurobiol. 43(2):124-30. Epub 2011 Jan 15. Review
        • Killick R, Niklison-Chirou M, Tomasini R, Bano D, Rufini A, Grespi F, Velletri T, Tucci P, Sayan BS, Conforti F, Gallagher E, Nicotera P, Mak TW, Melino G, Knight RA, Agostini M (2011). pa multifunctional protein in neurobiology. Mol Neurobiol. 43(2):139-46. Epub 2011 Mar 8. Review
        • Levi-Montalcini R, Knight RA, Nicotera P, Nisticó G, Bazan N, Melino G (2011). Rita's 102!! Mol Neurobiol. 43(2):77-9
        • Lippi G, Steinert JR, Marczylo EL, D'Oro S, Fiore R, Forsythe ID, Schratt G, Zoli M, Nicotera P, Young KW (2011). Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology. J Cell Biol. Sep 19;194(6):889-904
        • Nicotera P, Hampel H (2011). Perspectives of worldwide translational biomarker research in neurodegenerative diseases. Prog Neurobiol. 95(4):496-7. Epub 2011 Jul 23
        • Orrenius S, Nicotera P, Zhivotovsky B (2011). Cell death mechanisms and their implications in toxicology. Toxicol Sci. 119(1):3-19. Epub 2010 Sep 9. Review
        • Ziviani E, Lippi G, Bano D, Munarriz E, Guiducci S, Zoli M, Young KW, Nicotera P (2011). Ryanodine receptor-2 upregulation and nicotine-mediated plasticity. EMBO J. Jan 5;30(1):194-204. Epub 2010 Nov 26

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        Carien M. Niessen

        • Cianfarani F, Bernardini S, De Luca N, Dellambra E, Tatangelo L, Tiveron C, Niessen CM, Zambruno G, Castiglia D, Odorisio T (2011). Impaired keratinocyte proliferative and clonogenic potential in transgenic mice overexpressing 14-3-3σ in the epidermis. J Invest Dermatol. 131(9):1821-9. doi: 10.1038/jid.2011.137. Epub 2011 Jun 9
        • Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Günschmann C, Sandhoff K, Niessen CM, Niemann C (2011). TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function. J Invest Dermatol. Sep 22. doi: 10.1038/jid.2011.301. Epub 2011 Sep 22
        • Kirschner N, Haftek M, Niessen CM, Behne MJ, Furuse M, Moll I, Brandner JM (2011). CD44 regulates tight-junction assembly and barrier function. J Invest Dermatol. Apr;131(4):932-43. Epub 2010 Dec 30
        • Niessen CM, Leckband D, Yap AS (2011). Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation. Physiol Rev. 91(2):691-731. Review
        • Weber S, Niessen MT, Prox J, Lüllmann-Rauch R, Schmitz A, Schwanbeck R, Blobel CP, Jorissen E, de Strooper B, Niessen CM, Saftig P (2011). The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling. Development. 138(3):495-505

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        Angelika A. Noegel

        • Heidel AJ, Lawal HM, Felder M, Schilde C, Helps NR, Tunggal B, Rivero F, John U, Schleicher M, Eichinger L, Platzer M, Noegel AA, Schaap P, Glöckner G (2011). Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication. Genome Res. 21(11):1882-91. Epub 2011 Jul 14
        • Noegel AA, Neumann S (2011). The role of nesprins as multifunctional organizers in the nucleus and the cytoskeleton. Biochem Soc Trans. 39(6):1725-8
        • Rashmi RN, Eckes B, Glöckner G, Groth M, Neumann S, Gloy J, Sellin L, Walz G, Schneider M, Karakesisoglou I, Eichinger L, Noegel AA (2011). The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus. Mar 1;3(2). Epub 2012 Mar 1
        • Riyahi TY, Frese F, Steinert M, Omosigho NN, Glöckner G, Eichinger L, Orabi B, Williams RS, Noegel AA (2011). RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense. PLoS One. 6(11):e27311. Epub 2011 Nov 2
        • Schneider M, Lu W, Neumann S, Brachner A, Gotzmann J, Noegel AA, Karakesisoglou I (2011). Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope. Cell Mol Life Sci. 68(9):1593-610. Epub Oct 5
        • Shina MC, Müller-Taubenberger A, Unal C, Schleicher M, Steinert M, Eichinger L, Müller R, Blau-Wasser R, Glöckner G, Noegel AA (2011). Redundant and unique roles of coronin proteins in Dictyostelium.
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        • Sitar T, Gallinger J, Ducka AM, Ikonen TP, Wohlhoefler M, Schmoller KM, Bausch AR, Joel P, Trybus KM, Noegel AA, Schleicher M, Huber R, Holak TA (2011). Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly. Proc Natl Acad Sci U S A. Dec 6;108(49):19575-80. Epub 2011 Nov 21

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        Peter Nürnberg

        • Ahmad A, Daud S, Kakar N, Nürnberg G, Nürnberg P, Babar ME, Thoenes M, Kubisch C, Ahmad J, Bolz HJ (2011). Identification of a novel LCA5 mutation in a Pakistani family with Leber congenital amaurosis and cataracts. Mol Vis. 17:1940-5. Epub 2011 Jul 16
        • Baasanjav S, Al-Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn D, Seelow D, Ali BR, Aziz SA, Langer R, Saleh AA, Becker C, Nürnberg G, Cantagrel V, Gleeson JG, Gomez D, Michel JB, Stricker S, Lindner TH, Nürnberg P, Sugahara K, Mundlos S, Hoffmann K (2011). Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. Am J Hum Genet. Jul 15;89(1):15-27
        • Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ (2011). Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Nat Neurosci. Jan 12;14(1):77-84. Epub 2010 Dec 5
        • Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nürnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Müller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C (2011). Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet. Feb 11;88(2):127-37. Epub 2011 Jan 20
        • Dafinger C, Liebau MC, Elsayed SM, Hellenbroich Y, Boltshauser E, Korenke GC, Fabretti F, Janecke AR, Ebermann I, Nürnberg G, Nürnberg P, Zentgraf H, Koerber F, Addicks K, Elsobky E, Benzing T, Schermer B, Bolz HJ (2011). Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. J Clin Invest. Jul 10;121(7):2662-7. doi: 10.1172/JCI43639
        • Debrah AY, Batsa L, Albers A, Mand S, Toliat MR, Nürnberg P, Adjei O, Hoerauf A, Pfarr K (2011). Transforming growth factor-β1 variant Leu10Pro is associated with both lack of microfilariae and differential microfilarial loads in the blood of persons infected with lymphatic filariasis. Hum Immunol. Nov 14;72(11):1143-8. Epub 2011 Jul 31
        • Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, Nürnberg P, Giele H, Ophoff RA, Wijmenga C, Dutch Dupuytren Study Group; German Dupuytren Study Group; LifeLines Cohort Study; BSSH-GODD Consortium (2011). Wnt signaling and Dupuytren's disease. N Engl J Med. Jul 28;365(4):307-17. Epub 2011 Jul 6
        • du Moulin M, Nürnberg P, Crow YJ, Rutsch F (2011). Cerebral vasculopathy is a common feature in Aicardi-Goutieres syndrome associated with SAMHD1 mutations. Proc Natl Acad Sci U S A. Jun 28;108(26):E232; author reply E233. Epub 2011 Jun 1
        • Huebner AK, Gandia M, Frommolt P, Maak A, Wicklein EM, Thiele H, Altmüller J, Wagner F, Viñuela A, Aguirre LA, Moreno F, Maier H, Rau I, Giesselmann S, Nürnberg G, Gal A, Nürnberg P, Hübner CA, del Castillo I, Kurth I (2011). Nonsense mutations in SMPX, encoding a protein responsive to physical force, result in X-chromosomal hearing loss. Am J Hum Genet. May 13;88(5):621-7. Epub 2011 May 5
        • Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F (2011). COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest. May 20;121(5):2013-24. doi: 10.1172/JCI45693. Epub 2011 Apr 11
        • Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert R, Hampe J (2011). Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors. PLoS One. 6(7):e21332. Epub 2011 Jul 5
        • Kalay E, Yigit G, Aslan Y, Brown KE, Pohl E, Bicknell LS, Kayserili H, Li Y, Tüysüz B, Nürnberg G, Kiess W, Koegl M, Baessmann I, Buruk K, Toraman B, Kayipmaz S, Kul S, Ikbal M, Turner DJ, Taylor MS, Aerts J, Scott C, Milstein K, Dollfus H, Wieczorek D, Brunner HG, Hurles M, Jackson AP, Rauch A, Nürnberg P, Karagüzel A, Wollnik B (2011). CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet. 43(1):23-6. Epub 2010 Dec 5
        • Krumbiegel M, Pasutto F, Schlötzer-Schrehardt U, Uebe S, Zenkel M, Mardin CY, Weisschuh N, Paoli D, Gramer E, Becker C, Ekici AB, Weber BH, Nürnberg P, Kruse FE, Reis A (2011). Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome. Eur J Hum Genet. 19(2):186-93. Epub 2010 Sep 1
        • Querings S, Altmüller J, Ansén S, Zander T, Seidel D, Gabler F, Peifer M, Markert E, Stemshorn K, Timmermann B, Saal B, Klose S, Ernestus K, Scheffler M, Engel-Riedel W, Stoelben E, Brambilla E, Wolf J, Nürnberg P, Thomas RK (2011). Benchmarking of mutation diagnostics in clinical lung cancer specimens. PLoS One. May 5;6(5):e19601
        • Schmid F, Glaus E, Barthelmes D, Fliegauf M, Gaspar H, Nürnberg G, Nürnberg P, Omran H, Berger W, Neidhardt J (2011). U1 snRNA-mediated gene therapeutic correction of splice defects caused by an exceptionally mild BBS mutation. Hum Mutat. Jul 9;32(7):815-24. doi: 10.1002/humu.21509

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        Linda Partridge

        • Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L (2011). Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Mol Syst Biol. Jun 21;7:502. doi: 10.1038/msb.2011.36
        • Alic N, Partridge L (2011). Death and dessert: nutrient signalling pathways and ageing. Curr Opin Cell Biol. Dec;23(6):738-43. Epub 2011 Aug 9
        • Alic N, Hoddinott MP, Vinti G, Partridge L (2011). Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. Aging Cell. Feb;10(1):137-47. doi: 10.1111/j.1474-9726.2010.00653.x
        • Augustin H, Allen MJ, Partridge L (2011). Electrophysiological recordings from the giant fiber pathway of D. melanogaster. J Vis Exp. Jan 14;(47). pii: 2412. doi: 10.3791/2412
        • Bjedov I, Partridge L (2011). A longer and healthier life with TOR down-regulation: genetics and drugs. Biochem Soc Trans. Apr;39(2):460-5. Review
        • Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG (2011). The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PLoS Genet. Oct;7(10):e1002324. Epub 2011 Oct 13
        • Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D (2011). Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. Sep 21;477(7365):482-5. doi: 10.1038/nature10296
        • Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP (2011). Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metab. Mar 2;13(3):340-50
        • Lee SF, Chen Y, Varan AK, Wee CW, Rako L, Axford JK, Good RT, Blacket MJ, Reuter C, Partridge L, Hoffmann AA (2011). Molecular basis of adaptive shift in body size in Drosophila melanogaster: functional and sequence analyses of the Dca gene. Mol Biol Evol. Aug;28(8):2393-402. Epub 2011 Apr 4
        • Partridge L (2011). Some highlights of research on aging with invertebrates, 2010. Aging Cell. Feb;10(1):5-9. doi: 10.1111/j.1474-9726.2010.00649.x. Epub 2010 Dec 7. Review
        • Selman C, Partridge L, Withers DJ (2011) Replication of extended lifespan phenotype in mice with deletion of insulin receptor substrate 1. PLoS One. Jan 25;6(1):e16144
        • Partridge L, Alic N, Bjedov I, Piper MD (2011). Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Exp Gerontol. May;46(5):376-81. Epub 2010 Sep 16. Review
        • Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC (2011). Unraveling the biological roles of reactive oxygen species. Cell Metab. Apr 6;13(4):361-6
        • Partridge L, Thornton J, Bates G (2011). The new science of ageing. Philos Trans Soc B Biol Sci. Jan 12;366(1561):6-8
        • Piper MD, Partridge L, Raubenheimer D, Simpson SJ (2011). Dietary restriction and aging: a unifying perspective. Cell Metab. Aug 3;14(2):154-60
        • Slack C, Giannakou ME, Foley A, Goss M, Partridge L (2011). dFOXO-independent effects of reduced insulin-like signaling in Drosophila. Aging Cell. Oct;10(5):735-48. doi: 10.1111/j.1474-9726.2011.00707.x. Epub 2011 May 6
        • Wigby S, Slack C, Grönke S, Martinez P, Calboli FC, Chapman T, Partridge L (2011). Insulin signalling regulates remating in female Drosophila. Proc Biol Sci. Feb 7;278(1704):424-31. Epub 2010 Aug 25

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        Manolis Pasparakis

        • Bonnet MC, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W, Haase I, Pasparakis M (2011). The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation. Immunity. 35(4):572-82.
        • Ehlken H, Kondylis V, Heinrichsdorff J, Ochoa-Callejero L, Roskams T, Pasparakis M (2011). Hepatocyte IKK2 Protects Mdr2 Mice from Chronic Liver Failure. PLoS One. 6(10):e25942
        • Ikeda F, Deribe YL, Skånland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJ, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I (2011). SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature. 471(7340):637-41
        • Isfort K, Ebert F, Bornhorst J, Sargin S, Kardakaris R, Pasparakis M, Baehler M, Schwerdtle T, Schwab A, Hanley PJ (2011). Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to C5a is PI3K- and p38 MAPK-independent. J Biol Chem. 286(52):44776-87
        • Kardakaris R, Gareus R, Xanthoulea S, Pasparakis M (2011). Endothelial and Macrophage-Specific Deficiency of P38α MAPK Does Not Affect the Pathogenesis of Atherosclerosis in ApoE Mice. PLoS One. 6(6):e21055
        • Lippens S, Lefebvre S, Gilbert B, Sze M, Devos M, Verhelst K, Vereecke L, Guire CM, Guérin C, Vandenabeele P, Pasparakis M, Mikkola ML, Beyaert R, Declercq W, van Loo G (2011). Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis. Cell Death Differ. 18(12): 1845–1853
        • Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, Geboes L, Louagie E, Guire CM, Vereecke L, Chu Y, Boon L, Staelens S, Matthys P, Lambrecht BN, Schmidt-Supprian M, Pasparakis M, Elewaut D, Beyaert R, van Loo G (2011). A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis. Nat Genet. 43(9):908-12
        • Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Turco DD, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M (2011). IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system. Brain. 134(4): 1184-94
        • Schnitger AK, Machova A, Mueller RU, Androulidaki A, Schermer B, Pasparakis M, Krönke M, Papadopoulou N (2011). Listeria monocytogenes infection in macrophages induces vacuolar-dependent host miRNA response. PLoS One. 6(11):e27435     
        • Vlantis K, Wullaert A, Sasaki Y, Schmidt-Supprian M, Rajewsky K, Roskams T, Pasparakis M (2011). Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice. J Clin Invest. 121(7):2781-93
        • Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M (2011). FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature. 477: 330-4
        • Wullaert A, Bonnet MC, Pasparakis M (2011). NF-κB in the regulation of epithelial homeostasis and inflammation. Cell Res. 21(1):146-58

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        Mats Paulsson

        • Gara SK, Grumati P, Squarzoni S, Sabatelli P, Urciuolo A, Bonaldo P, Paulsson M, Wagener R (2011). Differential and restricted expression of novel collagen VI chains in mouse. Matrix Biol. May;30(4):248-57. doi: 10.1016/j.matbio.2011.03.006. Epub 2011 Apr 6
        • Groma G, Grskovic I, Schael S, Ehlen HW, Wagener R, Fosang A, Aszodi A, Paulsson M, Brachvogel B, Zaucke F (2011). Matrilin-4 is processed by ADAMTS-5 in late Golgi vesicles present in growth plate chondrocytes of defined differentiation state. Matrix Biol. May;30(4):275-80. doi: 10.1016/j.matbio.2011.04.002. Epub 2011 Apr 22
        • Hansen U, Platz N, Becker A, Bruckner P, Paulsson M, Zaucke F (2011). A secreted variant of cartilage oligomeric matrix protein carrying a chondrodysplasia-causing mutation (p.H587R) disrupts collagen fibrillogenesis. Arthritis Rheum. Jan;63(1):159-67. doi: 10.1002/art.30073
        • Iorga B, Neacsu CD, Neiss WF, Wagener R, Paulsson M, Stehle R, Pfitzer G (2011). Micromechanical function of myofibrils isolated from skeletal and cardiac muscles of the zebrafish. J Gen Physiol. Mar;137(3):255-70
        • Klatt AR, Becker AK, Neacsu CD, Paulsson M, Wagener R (2011). The matrilins: modulators of extracellular matrix assembly. Int J Biochem Cell Biol. Mar;43(3):320-30. Epub 2010 Dec 14. Review
        • Neacsu CD, Grosch M, Tejada M, Winterpacht A, Paulsson M, Wagener R, Tagariello A (2011). Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation. Matrix Biol. Sep;30(7-8):369-78. Epub 2011 Aug 1
        • Rosenbaum S, Kreft S, Etich J, Frie C, Stermann J, Grskovic I, Frey B, Mielenz D, Pöschl E, Gaipl U, Paulsson M, Brachvogel B (2011). Identification of novel binding partners (annexins) for the cell death signal phosphatidylserine and definition of their recognition motif. J Biol Chem. Feb 18;286(7):5708-16. Epub 2010 Dec 3
        • Sabatelli P, Gara SK, Grumati P, Urciuolo A, Gualandi F, Curci R, Squarzoni S, Zamparelli A, Martoni E, Merlini L, Paulsson M, Bonaldo P, Wagener R (2011). Expression of the collagen VI α5 and α6 chains in normal human skin and in skin of patients with collagen VI-related myopathies. J Invest Dermatol. Jan;131(1):99-107. Epub 2010 Sep 30
        • Sabatelli P, Gualandi F, Gara SK, Grumati P, Zamparelli A, Martoni E, Pellegrini C, Merlini L, Ferlini A, Bonaldo P, Maraldi NM, Paulsson M, Squarzoni S, Wagener R (2011). Expression of collagen VI α5 and α6 chains in human muscle and in Duchenne muscular dystrophy-related muscle fibrosis. Matrix Biol. Dec 30. Epub 2011 Dec 30

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        Alvaro Rada-Iglesias

        • Enroth S, Rada-Iglesias A, Andersson R, Wallerman O, Wanders A, Påhlman L, Komorowski J, Wadelius C (2011). Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa. BMC Cancer. Oct 19; 11:450
        • Ma Z, Swigut T, Valouev A, Rada-Iglesias A, Wysocka J (2011). Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates. Nat Struct Mol Biol. Feb;18(2):120-7
        • Rada-Iglesias A, Wysocka J (2011). Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease. Genome Med. Jun 7;3(6):36
        • Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J (2011). A unique chromatin signature uncovers early developmental enhancers in humans. Nature. Feb 10;470(7333):279-83

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        Hans Christian Reinhardt

        • Habbig S, Bartram MP, Müller RU, Schwarz R, Andriopoulos N, Chen S, Sägmüller JG, Hoehne M, Burst V, Liebau MC, Reinhardt HC, Benzing T, Schermer B (2011). NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. J Cell Biol. May 16;193(4):633-42. Epub 2011 May 9
        • Herter-Sprie GS, Chen S, Höpker K, Reinhardt HC (2011). Synthetic lethality as a new concept for the treatment of cancer. Dtsch Med Wochenschr. Jul;136(30):1526-30. doi: 10.1055/s-0031-1281549. Epub 2011 Jul 25. Review. German
        • Höhne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Gödel M, Helmstädter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, Benzing T (2011). The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins. Mol Cell Biol. Aug;31(16):3241-51. Epub 2011 Jun 20
        • Reinhardt HC, Cannell IG, Morandell S, Yaffe MB (2011). Is post-transcriptional stabilization, splicing and translation of selective mRNAs a key to the DNA damage response? Cell Cycle. Jan 1;10(1):23-7. Epub 2011 Jan 1. Review

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        Elena Rugarli

        • Pierson TM, Adams D, Bonn F, Martinelli P, Cherukuri PF, Teer JK, Hansen NF, Cruz P, Mullikin For The Nisc Comparative Sequencing Program JC, Blakesley RW, Golas G, Kwan J, Sandler A, Fuentes Fajardo K, Markello T, Tifft C, Blackstone C, Rugarli EI, Langer T, Gahl WA, Toro C (2011). Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genet. 2011 Oct;7(10):e1002325. Epub 2011 Oct 13
        • Vantaggiato C, Bondioni S, Airoldi G, Bozzato A, Borsani G, Rugarli EI, Bresolin N, Clementi E, Bassi MT (2011). Senataxin modulates neurite growth through fibroblast growth factor 8 signalling. Brain. 2011 Jun;134(Pt 6):1808-28. Epub 2011 May 15

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        Markus Schubert

        • Blumbach K, Niehoff A, Belgardt BF, Ehlen HW, Schmitz M, Hallinger R, Schulz JN, Bruning JC, Gullberg D, Krieg T, Schubert M, Eckes B (2011). Dwarfism in Mice Lacking Collagen-Binding Integrins α2β1 and α11β1 Is Caused by Severely Diminished IGF-1 Levels. J Biol Chem. Dec 30. Epub 2011 Dec 30
        • Freude S, Schilbach K, Hettich MM, Brönneke HS, Zemva J, Krone W, Brüning JC, Schubert M (2011). Neuron-specific deletion of one copy of the insulin-like growth factor-1 receptor gene causes extended lifespan in male mice. Horm Metab Res. In press
        • Stöhr O, Hahn J, Moll L, Leeser U, Freude S, Bernard C, Schilbach K, Markl A, Udelhoven M, Krone W, Schubert M (2011). Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells. Biochim Biophys Acta. May;1812(5):573-80. Epub 2011 Feb 24
        • Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M (2011). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. Age (Dordr). 2011 Nov 6
        • Zemva J, Schilbach K, Stöhr O, Moll L, Franko A, Wiesner R, Krone W, Schubert M (2011). Central FoxO3a and 6 expression is downregulated in response to high fat diet induced diabetes but not during aging. Exp Clin Endocrinol Diabetes. In press
        • Zemva J, Schubert M (2011). Central insulin and insulin-like growth factor-1 signaling: implications for diabetes associated dementia. Curr Diabetes Rev. Sep 1;7(5):356-66

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        Günter Schwarz

        • Belaidi AA, Arjune S, Santamaria-Araujo JS, Sass JO, Schwarz G (2011
). Molybdenum cofactor deficiency: a new HPLC method for fast quantification of S-sulfocysteine in urine and serum.
 J Inh Met Dis Reports. Epub 2011 Dec 17
        • Bevers LE, Schwarz G, Hagen WR (2011). 
A molecular basis for tungstate selectivity in prokaryotic ABC-transport systems.
 J Bacteriol. 193: 4999-5001
        • Lambeck I, Chi JC, Krizowski S, Mueller S, Mehlmer N, Teige M, Fischer K, Schwarz G (2010). Kinetic analysis of 14-3-3-inhibited Arabidopsis thaliana nitrate reductase. Biochemistry. Sep 21;49(37):8177-86
        • Lambeck I, Fischer-Schrader K, Nick D, Röper J, Chi JC, Hille R, Schwarz G (2011). 
The molecular mechanism of 14-3-3-mediated inhibition of plant nitrate reductase. J Biol Chem. 287: 4562-4571
        • Mendel RR, Schwarz G (2011). 
Molybdenum cofactor biosynthesis in plants and humans.
 Coord Chem Rev. 255 : 1145-58
        • Ogino K, Ramsden SL, Keib N, Schwarz G, Harvey RJ, Hirata H (2011). 
Duplicated gephyrin genes showing distinct tissue distribution and alternative splicing patterns mediate molybdenum cofactor biosynthesis, glycine receptor clustering, and escape behavior in zebrafish. J Biol Chem. 286: 806-17
        • Santamaria-Araujo JA, Wray V, Schwarz G (2011). 
Structure and stability of the molybdenum cofactor intermediate cyclic pyranopterin monophosphate.
 J Biol Inorg Chem. Epub 2011 Aug 30
        • Specht CG, Grünewald N, Pascual O, Rostgaard N, Schwarz G, Triller A (2011
). Regulation of Glycine Receptor Diffusion Properties and Gephyrin Interaction by Protein Kinase C. EMBO J. 30: 3842-53
        • Veldman A, Hennermann JB, Schwarz G, van Spronsen F, Weis I, Wong FY, Schwahn BC (2011). Timing of Cerebral Developmental Disruption in Molybdenum Cofactor Deficiency. J Child Neurol. 26: 1059-60

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        Philipp Steven

        • Steven P, Bock F, Hüttmann G, Cursiefen C (2011). Intravital two-photon microscopy of immune cell dynamics in corneal lymphatic vessels. PLoS One. 6(10):e26253. Epub 2011 Oct 20

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        Peter Tessarz

        • Kohl C, Tessarz P, von der Malsburg K, Zahn R, Bukau B, Mogk A (2011). Cooperative and independent activities of Sgt2 and Get5 in the targeting of tail-anchored proteins. Biol Chem. 392, 601-608

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        Aleksandra Trifunovic

        • Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, Götz A, Forsström S, Salven P, Angers-Loustau A, Kopra OH, Tyynismaa H, Larsson NG, Wartiovaara K, Prolla T, Trifunovic A, Suomalainen A (2011). Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in polg mutator mice. Cell Metab. Jan 4;15(1):100-9
        • Hench J, Bratić Hench I, Pujol C, Ipsen S, Brodesser S, Mourier A, Tolnay M, Frank S, Trifunovic A (2011). A Tissue-Specific Approach to the Analysis of Metabolic Changes in Caenorhabditis elegans. PLoS One. 6(12):e28417. Epub 2011 Dec 5
        • Kukat A, Edgar D, Bratic I, Maiti P, Trifunovic A (2011). Random mtDNA mutations modulate proliferation capacity in mouse embryonic fibroblasts. Biochem Biophys Res Commun. Jun 10;409(3):394-9. Epub 2011 May 7

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        Clemens Wendtner

        • Wendtner CM (2011). Lenalidomide in CLL: what is the optimal dose? Clin Adv Hematol Oncol. Mar;9(3):220-4
        • von Bergwelt-Baildon MS, Kondo E, Klein-González N, Wendtner CM (2011). The cyclins: a family of widely expressed tumor antigens? Expert Rev Vaccines. Mar;10(3):389-95. Review
        • Krings Rocha C, Wendtner CM, Hallek M, Kreuzer KA (2011). Conventional cytogenetics in chronic lymphocytic leukemia (CLL). Leuk Res. Mar;35(3):e25. Epub 2010 Nov 11
        • Eichhorst BF, Fischer K, Fink AM, Elter T, Wendtner CM, Goede V, Bergmann M, Stilgenbauer S, Hopfinger G, Ritgen M, Bahlo J, Busch R, Hallek M (2011). German CLL Study Group (GCLLSG). Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis. Blood. Feb 10;117(6):1817-21. Epub 2010 Dec 7
        • Delank KS, Wendtner CM, Eich HT, Eysel P (2011). The treatment of spinal metastases. Dtsch Arztebl Int. Feb;108(5):71-9; quiz 80. Epub 2011 Feb 4. Review

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        Sara Wickström

        • Wickström SA, Fässler R (2011). Regulation of membrane traffic by integrin signaling. Trends Cell Biol. 21, 266-273
        • Wickström SA,  Radovanac K, Fässler R (2011). Genetic analyses of integrin signaling. Cold Spring Harb Perspect Biol. 3, a005116.r

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        Rudolf J. Wiesner

        • Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JF, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R, Wiesner RJ (2011). The Mitochondrial Electron Transport Chain is Dispensable for Proliferation and Differentiation of Epidermal Progenitor Cells. Stem Cells. Jul 20. 29, 1459-1468
        • Vlahou G, Eliáš M, von Kleist-Retzow JC, Wiesner RJ, Rivero F (2011). The Ras related GTPase Miro is not required for mitochondrial transport in Dictyostelium discoideum. Eur J Cell Biol. Apr;90(4):342-55. Epub 2010 Dec 4

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        Bernd Wollnik

        • Becker J, Semler O, Gilissen C, Li Y, Bolz HJ, Giunta C, Bergmann C, Rohrbach M, Koerber F, Zimmermann K, de Vries P, Wirth B, Schoenau E, Wollnik B, Veltman JA, Hoischen A, Netzer C (2011). Exome sequencing identifies truncating mutations in human SERPINF1 in autosomal-recessive osteogenesis imperfecta. Am J Hum Genet. Mar 11;88(3):362-71. Epub 2011 Feb 25
        • Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, Nürnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, Nürnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, Müller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C (2011). Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42. Am J Hum Genet. Feb 11;88(2):127-37. Epub 2011 Jan 20
        • Borck G, Wunram H, Steiert A, Volk AE, Körber F, Roters S, Herkenrath P, Wollnik B, Morris-Rosendahl DJ, Kubisch C (2011). A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome. Hum Genet. Jan;129(1):45-50. Epub 2010 Oct 22
        • Frenzel LP, Claus R, Plume N, Schwamb J, Konermann C, Pallasch CP, Claasen J, Brinker R, Wollnik B, Plass C, Wendtner CM (2011). Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus. Int J Cancer. May 15;128(10):2495-500. doi: 10.1002/ijc.25579
        • Kalay E, Yigit G, Aslan Y, Brown KE, Pohl E, Bicknell LS, Kayserili H, Li Y, Tüysüz B, Nürnberg G, Kiess W, Koegl M, Baessmann I, Buruk K, Toraman B, Kayipmaz S, Kul S, Ikbal M, Turner DJ, Taylor MS, Aerts J, Scott C, Milstein K, Dollfus H, Wieczorek D, Brunner HG, Hurles M, Jackson AP, Rauch A, Nürnberg P, Karagüzel A, Wollnik B (2011). CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet. Jan;43(1):23-6. Epub 2010 Dec 5
        • Kayserili H, Wollnik B, Güven G, Emiroğlu MU, Başerer N, Uyguner ZO (2011). A novel homozygous COL11A2 deletion causes a C-terminal protein truncation with incomplete mRNA decay in a Turkish patient. Am J Med Genet A. Jan;155A(1):180-5. doi: 10.1002/ajmg.a.33780
        • Laue K, Pogoda HM, Daniel PB, van Haeringen A, Alanay Y, von Ameln S, Rachwalski M, Morgan T, Gray MJ, Breuning MH, Sawyer GM, Sutherland-Smith AJ, Nikkels PG, Kubisch C, Bloch W, Wollnik B, Hammerschmidt M, Robertson SP (2011). Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. Am J Hum Genet. Nov 11;89(5):595-606. Epub 2011 Oct 20
        • Li Y, Bögershausen N, Alanay Y, Simsek Kiper PO, Plume N, Keupp K, Pohl E, Pawlik B, Rachwalski M, Milz E, Thoenes M, Albrecht B, Prott EC, Lehmkühler M, Demuth S, Utine GE, Boduroglu K, Frankenbusch K, Borck G, Gillessen-Kaesbach G, Yigit G, Wieczorek D, Wollnik B (2011). A mutation screen in patients with Kabuki syndrome. Hum Genet. May 24. Epub 2011 May 24

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        Thomas Wunderlich

        • Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, Wunderlich FT, Anders HJ, Klein L, Schmidt-Supprian M (2011). Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. Aug 29;208(9):1749-56. Epub 2011 Aug 15
        • Chaudhry A, Samstein RM, Treuting P, Liang Y, Pils MC, Heinrich JM, Jack RS, Wunderlich FT, Brüning JC, Müller W, Rudensky AY (2011). Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity. Apr 22;34(4):566-78
        • Jordan SD, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC (2011). Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol. Apr;13(4):434-46. Epub 2011 Mar 27
        • Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M (2011). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. Age (Dordr). Epub 2011 Nov 6

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