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Publications 2009

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Adam Antebi

  • Antebi A, Cuervo AM, Miller R, Sedivy J (2009). Announcements from your Editorial Team. Aging Cell.  Feb;8(1):1-1
  • Bethke A, Fielenbach N, Wang Z, Mangelsdorf DJ, Antebi A (2009). Nuclear hormone receptor regulation of microRNAs controls developmental progression. Science. Apr 3;324(5923):95-8
  • Bratic I, Hench J, Henriksson J, Antebi A, Bürglin TR, Trifunovic A (2009). Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development. Nucleic Acids Res. Apr;37(6):1817-28. Epub 2009 Jan 30
  • Ogawa A, Streit A, Antebi A, Sommer RJ (2009). A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes. Curr Biol. Jan 13;19(1):67-71. Epub 2008 Dec 24

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Hisham Bazzi

  • Bazzi H, Demehri S, Potter CS, Barber AG, Awgulewitsch A, Kopan R, Christiano AM (2009). Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation. Differentiation. 78(5), 292-300
  • Richardson GD, Bazzi H, Fantauzzo KA, Waters JM, Crawford H, Hynd P, Christiano AM, Jahoda CAB (2009). KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development. 136(13), 2153-64
  • Richardson GD, Fantauzzo KA, Bazzi H, Määttä A, Jahoda CAB (2009). Dynamic expression of Syndecan-1 during hair follicle morphogenesis. Gene Expr Patterns. 9, 454-60

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Thomas Benzing

  • Benzing T (2009). The promise of well-being: stay in shape with N(i)ck. J Am Soc Nephrol. Jul;20(7):1425-7. Epub 2009 Jun 4
  • Larsson E, Fredlund Fuchs P, Heldin J, Barkefors I, Bondjers C, Genové G, Arrondel C, Gerwins P, Kurschat C, Schermer B, Benzing T, Harvey SJ, Kreuger J, Lindahl P (2009). Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1. Genome Med. 2009 Nov 16;1(11):108
  • Müller RU, Fabretti F, Zank S, Burst V, Benzing T, Schermer B (2009). The von Hippel Lindau tumor suppressor limits longevity. J Am Soc Nephrol. Dec;20(12):2513-7. Epub 2009 Sep 24
  • Schermer B, Benzing T (2009). Lipid-protein interactions along the slit diaphragm of podocytes. J Am Soc Nephrol. Mar;20(3):473-8. Epub 2009 Feb 25

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Susanne Brodesser

  • Bach C, Gilch S, Rost R, Greenwood AD, Horsch M, Hajj GN, Brodesser S, Facius A, Schädler S, Sandhoff K, Beckers J, Leib-Mösch C, Schätzl HM, Vorberg I (2009). Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells. J Biol Chem. Nov 6;284(45):31260-9. Epub 2009 Sep 11

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Jens C. Brüning

  • Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT (2009). Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity. J Neurosci. Sep 16;29(37):11582-93
  • Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U (2009). Inactivation of the Fto gene protects from obesity. Nature. Apr 16;458(7240):894-8. Epub 2009 Feb 22
  • Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M (2009). Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J. Oct;23(10):3315-24. Epub 2009 Jun 1
  • Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M (2009). IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J Neurochem. 2008 Nov;107(4):907-17. Epub 2008 Sep 18
  • Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B (2009). Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. May;11(5):604-15. Epub 2009 Apr 12
  • Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM (2009). Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. J Clin Invest. Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8
  • Kleinridders A, Könner AC, Brüning JC (2009). CNS-targets in control of energy and glucose homeostasis. Curr Opin Pharmacol. Dec;9(6):794-804. Epub Oct 31
  • Belgardt BF, Okamura T, Brüning JC (2009). Hormone and glucose signalling in POMC and AgRP neurons. J Physiol. Nov 15;587(Pt 22):5305-14. Epub 2009 Sep 21
  • Kleinridders A, Pogoda HM, Irlenbusch S, Smyth N, Koncz C, Hammerschmidt M, Brüning JC (2009). PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis. Mol Cell Biol. Jun;29(11):3173-85. Epub 2009 Mar 23
  • Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC (2009). MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. Oct;10(4):249-59
  • Könner AC, Klöckener T, Brüning JC (2009). Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond. Physiol Behav. Jul 14;97(5):632-8. Epub 2009 Apr 5
  • Remedi MS, Kurata HT, Scott A, Wunderlich FT, Rother E, Kleinridders A, Tong A, Brüning JC, Koster JC, Nichols CG (2009). Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus. Cell Metab. Feb;9(2):140-51
  • Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J (2009). VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding. Thromb Haemost. Jun;101(6):1044-50
  • Yazdanpanah B, Wiegmann K, Tchikov V, Krut O, Pongratz C, Schramm M, Kleinridders A, Wunderlich T, Kashkar H, Utermöhlen O, Brüning JC, Schütze S, Krönke M (2009). Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. Aug 27;460(7259):1159-63. Epub 2009 Jul 29

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Oliver A. Cornely

  • Cornely OA, Böhme A, Buchheidt D, Einsele H, Heinz WJ, Karthaus M, Krause SW, Krüger W, Maschmeyer G, Penack O, Ritter J, Ruhnke M, Sandherr M, Sieniawski M, Vehreschild JJ, Wolf HH, Ullmann AJ (2009). Primary prophylaxis of invasive fungal infections in patients with hematologic malignancies. Recommendations of the Infectious Diseases Working Party of the German Society for Haematology and Oncology. Haematologica. Jan;94(1):113-22. Epub 2008 Dec 9
  • Elter T, Vehreschild JJ, Gribben J, Cornely OA, Engert A, Hallek M (2009). Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. Ann Hematol. Feb;88(2):121-32. Epub 2008 Aug 6
  • Glöckner A, Steinbach A, Vehreschild JJ, Cornely OA (2009). Treatment of invasive candidiasis with echinocandins. Mycoses. Nov;52(6):476-86
  • Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO), Böhme A, Ruhnke M, Buchheidt D, Cornely OA, Einsele H, Enzensberger R, Hebart H, Heinz W, Junghanss C, Karthaus M, Krüger W, Krug U, Kubin T, Penack O, Reichert D, Reuter S, Silling G, Südhoff T, Ullmann AJ, Maschmeyer G (2009). Treatment of invasive fungal infections in cancer patients--recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol. Feb;88(2):97-110. Epub 2008 Oct 14
  • Mann PA, McNicholas PM, Chau AS, Patel R, Mendrick C, Ullmann AJ, Cornely OA, Patino H, Black TA (2009). Impact of antifungal prophylaxis on colonization and azole susceptibility of Candida species. Antimicrob Agents Chemother. Dec;53(12):5026-34. Epub 2009 Sep 28
  • Maschmeyer G, Beinert T, Buchheidt D, Cornely OA, Einsele H, Heinz W, Heussel CP, Kahl C, Kiehl M, Lorenz J, Hof H, Mattiuzzi G (2009). Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients: Guidelines of the infectious diseases working party of the German Society of Haematology and Oncology. Eur J Cancer. Sep;45(14):2462-72. Epub 2009 May 23
  • Müller A, Klinkenberg D, Vehreschild J, Cornely O, Tillmann RL, Franzen C, Simon A, Schildgen O (2009). Low prevalence of human metapneumovirus and human bocavirus in adult immunocompromised high risk patients suspected to suffer from Pneumocystis pneumonia. J Infect. Mar;58(3):227-31. Epub 2009 Feb 10
  • Rueping MJ, Vehreschild JJ, Cornely OA (2009). Invasive candidiasis and candidemia: from current opinions to future perspectives. Expert Opin Investig Drugs. Jun;18(6):735-48
  • Vehreschild JJ, Sieniawski M, Reuter S, Arenz D, Reichert D, Maertens J, Böhme A, Silling G, Martino R, Maschmeyer G, Rüping MJ, Ullmann AJ, Cornely OA (2009). Efficacy of caspofungin and itraconazole as secondary antifungal prophylaxis: analysis of data from a multinational case registry. Int J Antimicrob Agents. Nov;34(5):446-50. Epub 2009 Aug 22

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Martin Denzel

  • Denzel MS, Hebbard LW, Shostak G, Shapiro L, Cardiff RD, Ranscht B (2009). Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer. Clinical Cancer Research. 15 (10), 3256-3264

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Sabine Eming

  • Buchstein N, Hoffmann N, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA (2009). Alternative proteolytic processing of hepatocyte growth factor during wound repair.  Am J Pathol. 174(6):2116-28
  • Eming SA, Hammerschmidt M, Krieg T, Roers A (2009). Interrelation of immunity and tissue repair or regeneration. Seminars in Cell and Developmental Biology. 20(5):517-27

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Lukas P. Frenzel

  • Frenzel LP, Abdullah Z, Kriegeskorte AK, Dieterich R, Lange N, Busch DH, Krönke M, Utermöhlen O, Hescheler J, Sarić T (2009). Role of natural-killer group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes. Stem Cells. Feb;27(2):307-16
  • Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM (2009). miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood. Oct 8;114(15):3255-64. Epub 2009 Aug 19

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Peter Frommolt

  • Frommolt P, Hellmich M (2009). Resampling in multiple-dose factorial designs. Biom J. Dec;51(6):915-31
  • Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, Heynck S, Beroukhim R, Lin W, Winckler W, Shah K, LaFramboise T, Moriarty WF, Hanna M, Tolosi L, Rahnenführer J, Verhaak R, Chiang D, Getz G, Hellmich M, Wolf J, Girard L, Peyton M, Weir BA, Chen TH, Greulich H, Barretina J, Shapiro GI, Garraway LA, Gazdar AF, Minna JD, Meyerson M, Wong KK, Thomas RK (2009). Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest. Jun;119(6):1727-40. doi: 10.1172/JCI37127. Epub 2009 May 18
  • Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, Gazdar AF, Minna JD, Garraway LA, Kashkar H, Pao W, Meyerson M, Thomas RK (2009). PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Res. Apr 15;69(8):3256-61. Epub 2009 Apr 7
  • Ullrich RT, Kracht L, Brunn A, Herholz K, Frommolt P, Miletic H, Deckert M, Heiss WD, Jacobs AH (2009). Methyl-L-11C-methionine PET as a diagnostic marker for malignant progression in patients with glioma. J Nucl Med. Dec;50(12):1962-8. Epub 2009 Nov 12

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Michael Hallek

  • Boucas J, Lux K, Huber A, Schievenbusch S, von Freyend MJ, Perabo L, Quadt-Humme S, Odenthal M, Hallek M, Büning H (2009). Engineering adeno-associated virus serotype 2-based targeting vectors using a new insertion site-position 453-and single point mutations. J Gene Med. Dec;11(12):1103-13
  • Eichhorst BF, Busch R, Stilgenbauer S, Stauch M, Bergmann MA, Ritgen M, Kranzhöfer N, Rohrberg R, Söling U, Burkhard O, Westermann A, Goede V, Schweighofer CD, Fischer K, Fink AM, Wendtner CM, Brittinger G, Döhner H, Emmerich B, Hallek M (2009). German CLL Study Group (GCLLSG). First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia. Blood. Oct 15;114(16):3382-91. Epub 2009 Jul 15
  • Eichhorst B, Goede V, Hallek M (2009). Treatment of elderly patients with chronic lymphocytic leukemia. Leuk Lymphoma. Feb;50(2):171-8. Review
  • Elter T, Kilp J, Borchmann P, Schulz H, Hallek M, Engert A (2009). Pharmacokinetics of alemtuzumab in combination with fludarabine in patients with relapsed or refractory B-cell chronic lymphocytic leukemia. Haematologica. Jan;94(1):150-2. Epub 2008 Nov 10
  • Elter T, Stipanov M, Heuser E, von Bergwelt-Baildon M, Bloch W, Hallek M, Baumann F (2009). Is physical exercise possible in patients with critical cytopenia undergoing intensive chemotherapy for acute leukaemia or aggressive lymphoma? Int J Hematol. Sep;90(2):199-204. Epub 2009 Jul 24
  • Elter T, Vehreschild JJ, Gribben J, Cornely OA, Engert A, Hallek M (2009). Management of infections in patients with chronic lymphocytic leukemia treated with alemtuzumab. Ann Hematol. Feb;88(2):121-32. Epub 2008 Aug 6. Review
  • Fingerle-Rowson G, Kaleswarapu DR, Schlander C, Kabgani N, Brocks T, Reinart N, Busch R, Schütz A, Lue H, Du X, Liu A, Xiong H, Chen Y, Nemajerova A, Hallek M, Bernhagen J, Leng L, Bucala R (2009). A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol. Apr;29(7):1922-32. Epub 2009 Feb 2
  • Gribben JG, Hallek M (2009). Rediscovering alemtuzumab: current and emerging therapeutic roles. Br J Haematol. Mar;144(6):818-31. Epub 2009 Jan 8. Review
  • Herling M, Patel KA, Weit N, Lilienthal N, Hallek M, Keating MJ, Jones D (2009). High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia. Blood. Nov 19;114(21):4675-86. Epub 2009 Sep 21
  • Hallek M (2009). State-of-the-art treatment of chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program. 2009:440-9. Review
  • Hallek M (2009). New menus for CLL treatment. Oncology (Williston Park). Nov 15;23(12):1046, 1051, 1056
  • Kunze M, Huber A, Krajewski A, Lowden E, Schuhmann N, Buening H, Hallek M, Noack M, Perabo L (2009). Efficient gene transfer to periodontal ligament cells and human gingival fibroblasts by adeno-associated virus vectors. J Dent. Jul;37(7):502-8. Epub 2009 Apr 11
  • Minke KS, Staib P, Puetter A, Gehrke I, Gandhirajan RK, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA (2009). Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells. Eur J Haematol. Mar;82(3):165-75. Epub 2008 Nov 20
  • Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM (2009). miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood. Oct 8;114(15):3255-64. Epub 2009 Aug 19
  • Pallasch CP, Ulbrich S, Brinker R, Hallek M, Uger RA, Wendtner CM (2009). Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade. Leuk Res. Mar;33(3):460-4. Epub 2008 Oct 5
  • Schweighofer CD, Ritgen M, Eichhorst BF, Busch R, Abenhardt W, Kneba M, Hallek M, Wendtner CM (2009). Consolidation with alemtuzumab improves progression-free survival in patients with chronic lymphocytic leukaemia (CLL) in first remission: long-term follow-up of a randomized phase III trial of the German CLL Study Group (GCLLSG). Br J Haematol. Jan;144(1):95-8. Epub 2008 Oct 30
  • Shimabukuro-Vornhagen A, Hallek MJ, Storb RF, von Bergwelt-Baildon MS (2009). The role of B cells in the pathogenesis of graft-versus-host disease. Blood. Dec 3;114(24):4919-27. Epub 2009 Sep 11. Review
  • Stilgenbauer S, Zenz T, Winkler D, Bühler A, Schlenk RF, Groner S, Busch R, Hensel M, Dührsen U, Finke J, Dreger P, Jäger U, Lengfelder E, Hohloch K, Söling U, Schlag R, Kneba M, Hallek M, Döhner H (2009). German Chronic Lymphocytic Leukemia Study Group. Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol. Aug 20;27(24):3994-4001. Epub 2009 Jul 13
  • Zenz T, Häbe S, Denzel T, Mohr J, Winkler D, Bühler A, Sarno A, Groner S, Mertens D, Busch R, Hallek M, Döhner H, Stilgenbauer S (2009). Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial. Blood. Sep 24;114(13):2589-97. Epub 2009 Jul 30

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Matthias Hammerschmidt

  • Dodd ME, Hatzold J, Mathias JR, Walters KB, Bennin DA, Rhodes J, Kanki JP, Look AT, Hammerschmidt M, Huttenlocher A (2009). The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish. Development. Aug;136(15):2591-600. Epub 2009 Jul 1
  • Eming SA, Hammerschmidt M, Krieg T, Roers A (2009). Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol. Jul;20(5):517-27. Epub 2009 Apr 22. Review
  • Hammond KL, Loynes HE, Mowbray C, Runke G, Hammerschmidt M, Mullins MC, Hildreth V, Chaudhry B, Whitfield TT (2009). A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner ear. PLoS One.;4(2):e4368. Epub 2009 Feb 3
  • Kleinridders A, Pogoda HM, Irlenbusch S, Smyth N, Koncz C, Hammerschmidt M, Brüning JC (2009). PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis. Mol Cell Biol. Jun;29(11):3173-85. Epub 2009 Mar 23
  • Pogoda HM, Hammerschmidt M (2009). How to make a teleost adenohypophysis: molecular pathways of pituitary development in zebrafish. Mol Cell Endocrinol. Nov 27;312(1-2):2-13. Epub 2009 Mar 28. Review
  • Slanchev K, Carney TJ, Stemmler MP, Koschorz B, Amsterdam A, Schwarz H, Hammerschmidt M (2009). The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet. Jul;5(7):e1000563. Epub 2009 Jul 17

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Hans Christian Hennies

  • Alef T, Torres S, Hausser I, Metze D, Türsen U, Lestringant GG , Hennies HC (2009). Ichthyosis, follicular atrophoderma, and hypotrichosis caused by mutations in ST14 is associated with impaired profilaggrin processing. J Invest Dermatol. Apr;129(4):862-9. Epub 2008 Oct 9
  • Aufenvenne K, Oji V, Walker T, Becker-Pauly C, Hennies HC, Stöcker W , Traupe H (2009). Transglutaminase-1 and bathing suit ichthyosis: molecular analysis of gene/environment interactions. J Invest Dermatol. Aug;129(8):2068-71. Epub 2009 Feb 12
  • Basel-Vanagaite L, Sarig O, Hershkovitz D, Fuchs-Telem D, Rapaport D, Gat A, Isman G, Shirazi I, Shohat M, Enk CD, Birk E, Kohlhase J, Matysiak-Scholze U, Maya I, Knopf C, Peffekoven A, Hennies HC, Bergman R, Horowitz M, Ishida-Yamamoto A , Sprecher E (2009). RIN2 deficiency results in macrocephaly, alopecia, cutis laxa, and scoliosis: MACS syndrome. Am J Hum Genet. Aug;85(2):254-63. Epub 2009 Jul 23
  • Eckl KM, de Juanes S, Kurtenbach J, Nätebus M, Lugassy J, Oji V, Traupe H, Preil ML, Marinez F, Smolle J, Harel A, Krieg P, Sprecher E, Hennies HC (2009). Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: Evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B. J Invest Dermatol 129: 1421-1428
  • Seifert W, Holder-Espinasse M, Kühnisch J, Kahrizi K, Tzschach A, Garshasbi M, Najmabadi H, Walter Kuss A, Kress W, Laureys G, Loeys B, Brilstra E, Mancini GM, Dollfus H, Dahan K, Apse K, Hennies HC , Horn D (2009). Expanded mutational spectrum in Cohen syndrome, tissue expression, and transcript variants of COH1. Hum Mutat. Feb;30(2):E404-20
  • zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka G, Griffiths G, Ehl S , Hennies HC (2009). Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11. Am J Hum Genet. Oct;85(4):482-92

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Marco Herling

  • Herling M, Patel KA, Weit N, Lilienthal N, Hallek M, Keating MJ, Jones D (2009). High TCL1 levels are a marker of B-cell receptor pathway responsiveness and therapy resistance in chronic lymphocytic leukemia. Blood. Nov 19;114(21):4675-86. Epub 2009 Sep 21

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Thorsten Hoppe

  • Deichsel A, Mouysset J, Hoppe T (2009). The ubiquitin-selective chaperone CDC-48/p97, a new player in DNA replication. Cell Cycle. 8, 1-6
  • Hoppe T (2009). Less is more: how protein degradation regulates muscle development. Ernst Schering Found Symp Proc. 1, 67-73
  • Segref A, Hoppe T (2009). Think locally: control of ubiquitin-dependent protein degradation in neurons. EMBO reports. 10, 44-50

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Hamid Kashkar

  • Herz J, Pardo J, Kashkar H, Schramm M, Kuzmenkina E, Bos E, Wiegmann K, Wallich R, Peters PJ, Herzig S, Schmelzer E, Krönke M, Simon MM, Utermöhlen O (2009). Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes. Nat Immunol. Jul;10(7):761-8. Epub 2009 Jun 14
  • Mertens J, Fabri M, Zingarelli A, Kubacki T, Meemboor S, Groneck L, Seeger J, Bessler M, Hafke H, Odenthal M, Bieler JG, Kalka C, Schneck JP, Kashkar H, Kalka-Moll WM (2009). Streptococcus pneumoniae serotype 1 capsular polysaccharide induces CD8CD28 regulatory T lymphocytes by TCR crosslinking. PLoS Pathog. Sep;5(9):e1000596. Epub 2009 Sep 25
  • Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, Gazdar AF, Minna JD, Garraway LA, Kashkar H, Pao W, Meyerson M, Thomas RK (2009). PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Res. Apr 15;69(8):3256-61. Epub 2009 Apr 7
  • Yazdanpanah B, Wiegmann K, Tchikov V, Krut O, Pongratz C, Schramm M, Kleinridders A, Wunderlich T, Kashkar H, Utermöhlen O, Brüning JC, Schütze S, Krönke M (2009). Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. Aug 27;460(7259):1159-63. Epub 2009 Jul 29

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Peter Kloppenburg

  • Demmer H, Kloppenburg P (2009). Intrinsic membrane properties and inhibitory synaptic input of kenyon cells as mechanisms for sparse coding? J Neurophysiol. Sep;102(3):1538-50. Epub 2009 Jun 24
  • Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT (2009). Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity. J Neurosci. Sep 16;29(37):11582-93
  • Husch A, Paehler M, Fusca D, Paeger L, Kloppenburg P (2009). Calcium current diversity in physiologically different local interneuron types of the antennal lobe. J Neurosci. Jan 21;29(3):716-26
  • Husch A, Paehler M, Fusca D, Paeger L, Kloppenburg P (2009). Distinct electrophysiological properties in subtypes of nonspiking olfactory local interneurons correlate with their cell type-specific Ca2+ current profiles. J Neurophysiol. Nov;102(5):2834-45. Epub 2009 Sep 16
  • Pippow A, Husch A, Pouzat C, Kloppenburg P (2009). Differences of Ca2+ handling properties in identified central olfactory neurons of the antennal lobe. Cell Calcium. Aug;46(2):87-98. Epub 2009 Jul 9

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Thomas Krieg

  • Buchstein N, Hoffmann D, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA (2009). Alternative proteolytic processing of hepatocyte growth factor during wound repair. Am J Pathol. Jun;174(6):2116-28. Epub 2009 Apr 23
  • Eming SA, Hammerschmidt M, Krieg T, Roers A (2009). Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol. Jul;20(5):517-27. Epub 2009 Apr 22. Review
  • Gabrielli A, Avvedimento EV, Krieg T (2009). Scleroderma. N Engl J Med. May 7;360(19):1989-2003. Review
  • Hunzelmann N, Moinzadeh P, Genth E, Krieg T, Lehmacher W, Melchers I, Meurer M, Müller-Ladner U, Olski TM, Pfeiffer C, Riemekasten G, Schulze-Lohoff E, Sunderkoetter C, Weber M; German Network for Systemic Scleroderma Centers (2009). High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy. Arthritis Res Ther. 2009;11(2):R30. Epub 2009 Mar 4
  • Kreuter A, Krieg T, Worm M, Wenzel J, Gambichler T, Kuhn A, Aberer E, Scharffetter-Kochanek K, Hunzelmann N (2009). Deutsche Dermatologische Gesellschaft. AWMF Guideline no. 013/066. Diagnosis and therapy of circumscribed scleroderma. J Dtsch Dermatol Ges. Sep;7 Suppl 6:S1-14. German
  • Krieg T, Liu Y, Rütz T, Methner C, Yang XM, Dost T, Felix SB, Stasch JP, Cohen MV, Downey JM (2009). BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts. Eur Heart J. Jul;30(13):1607-13. Epub 2009 Apr 30
  • Michels C, Buchta T, Bloch W, Krieg T, Niessen CM (2009). Classical cadherins regulate desmosome formation. J Invest Dermatol. Aug;129(8):2072-5. Epub 2009 Mar 5
  • Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV (2009). Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood. Nov 26;114(23):4897-906. Epub 2009 Sep 29
  • Terheyden P, Grimberg G, Hausser I, Rose C, Korge BP, Krieg T, Arin MJ (2009). Recessive epidermolytic hyperkeratosis caused by a previously unreported termination codon mutation in the keratin 10 gene. J Invest Dermatol. Nov;129(11):2721-3. Epub 2009 May 28
  • Wieland U, Mauch C, Kreuter A, Krieg T, Pfister H (2009). Merkel cell polyomavirus DNA in persons without merkel cell carcinoma. Emerg Infect Dis. Sep;15(9):1496-8

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Martin Krönke

  • Frenzel LP, Abdullah Z, Kriegeskorte AK, Dieterich R, Lange N, Busch DH, Krönke M, Utermöhlen O, Hescheler J, Sarić T (2009). Role of natural-killer group 2 member D ligands and intercellular adhesion molecule 1 in natural killer cell-mediated lysis of murine embryonic stem cells and embryonic stem cell-derived cardiomyocytes. Stem Cells. Feb;27(2):307-16
  • Glowalla E, Tosetti B, Krönke M, Krut O (2009). Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus. Infect Immun. Jul;77(7):2719-29. Epub 2009 Apr 13
  • Herz J, Pardo J, Kashkar H, Schramm M, Kuzmenkina E, Bos E, Wiegmann K, Wallich R, Peters PJ, Herzig S, Schmelzer E, Krönke M, Simon MM, Utermöhlen O (2009). Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes. Nat Immunol. Jul;10(7):761-8. Epub 2009 Jun 14
  • Mathew SJ, Haubert D, Krönke M, Leptin M (2009). Looking beyond death: a morphogenetic role for the TNF signalling pathway. J Cell Sci. Jun 15;122(Pt 12):1939-46. Review
  • Palka-Santini M, Cleven BE, Eichinger L, Krönke M, Krut O (2009). Large scale multiplex PCR improves pathogen detection by DNA microarrays. BMC Microbiol. Jan 3;9:1
  • Utermöhlen O, Baschuk N, Abdullah Z, Engelmann A, Siebolts U, Wickenhauser C, Stocking C, Krönke M (2009). Immunologic hurdles of therapeutic stem cell transplantation. Biol Chem. Oct;390(10):977-83. Review
  • Yazdanpanah B, Wiegmann K, Tchikov V, Krut O, Pongratz C, Schramm M, Kleinridders A, Wunderlich T, Kashkar H, Utermöhlen O, Brüning JC, Schütze S, Krönke M (2009). Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. Aug 27;460(7259):1159-63. Epub 2009 Jul 29

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Wilhelm Krone

  • Berthold HK, Giannakidou E, Krone W, Mantzoros CS, Gouni-Berthold I (2009). The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes. Clin Chim Acta. Jan;399(1-2):112-6. Epub 2008 Sep 25
  • Berthold HK, Gouni-Berthold I, Böhm M, Krone W, Bestehorn KP (2009). Patterns and predictors of statin prescription in patients with type 2 diabetes. Cardiovasc Diabetol. May 13;8:25
  • Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M (2009). Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J. Oct;23(10):3315-24. Epub 2009 Jun 1
  • Gouni-Berthold I, Krone W, Berthold HK (2009). Vitamin D and cardiovascular disease. Curr Vasc Pharmacol. Jul;7(3):414-22. Review

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Christian Kubisch

  • Bchetnia M, Charfeddine C, Kassar S, Hanchi I, Tounsi-Guettiti H, Rebai A, Osman AD, Kubisch C, Abdelhak S, Boubaker S, Mokni M (2009). Clinical, histological and genetic investigation of Buschke-Fischer-Brauer's disease in Tunisian families. J Dermatol Sci. Apr;54(1):54-6. Epub 2009 Jan 10
  • Borck G, Seewi O, Jung A, Schönau E, Kubisch C (2009). Genetic causes of goiter and deafness: Pendred syndrome in a girl and cooccurrence of Pendred syndrome and resistance to thyroid hormone in her sister. J Clin Endocrinol Metab. Jun;94(6):2106-9. Epub 2009 Mar 24
  • Chung BD, Kayserili H, Ai M, Freudenberg J, Uzümcü A, Uyguner O, Bartels CF, Höning S, Ramirez A, Hanisch FG, Nürnberg G, Nürnberg P, Warman ML, Wollnik B, Kubisch C, Netzer C (2009). A mutation in the signal sequence of LRP5 in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeats. Hum Mutat. Apr;30(4):641-8
  • Haug K, Warnstedt M, Alekov AK, Sander T, Ramírez A, Poser B, Maljevic S, Hebeisen S, Kubisch C, Rebstock J, Horvath S, Hallmann K, Dullinger JS, Rau B, Haverkamp F, Beyenburg S, Schulz H, Janz D, Giese B, Müller-Newen G, Propping P, Elger CE, Fahlke C, Lerche H (2009). Retraction: Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. Nat Genet. Sep;41(9):1043
  • Karsak M, Malkin I, Toliat MR, Kubisch C, Nürnberg P, Zimmer A, Livshits G (2009). The cannabinoid receptor type 2 (CNR2) gene is associated with hand bone strength phenotypes in an ethnically homogeneous family sample. Hum Genet. Nov;126(5):629-36. Epub 2009 Jun 30
  • Kleefuss-Lie A, Friedl W, Cichon S, Haug K, Warnstedt M, Alekov A, Sander T, Ramirez A, Poser B, Maljevic S, Hebeisen S, Kubisch C, Rebstock J, Horvath S, Hallmann K, Dullinger JS, Rau B, Haverkamp F, Beyenburg S, Schulz H, Janz D, Giese B, Müller-Newen G, Propping P, Elger CE, Fahlke C, Lerche H (2009). CLCN2 variants in idiopathic generalized epilepsy. Nat Genet. Sep;41(9):954-5
  • Kubisch C (2009). Chromosomal microdeletions: minor imbalances with major consequences. Neurology. Mar 3;72(9):782-3. Epub 2008 Dec 10
  • Miró X, Zhou X, Boretius S, Michaelis T, Kubisch C, Alvarez-Bolado G, Gruss P (2009). Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. Dis Model Mech. Jul-Aug;2(7-8):412-8. Epub 2009 Jun 17
  • Schoser B, Jacob S, Hilton-Jones D, Müller-Felber W, Kubisch C, Claus D, Goebel HH, Vita G, Vincent A, Toscano A, Van den Bergh P (2009). Immune-mediated rippling muscle disease with myasthenia gravis: a report of seven patients with long-term follow-up in two. Neuromuscul Disord. Mar;19(3):223-8. Epub 2009 Feb 8
  • Todt U, Netzer C, Toliat M, Heinze A, Goebel I, Nürnberg P, Göbel H, Freudenberg J, Kubisch C (2009). New genetic evidence for involvement of the dopamine system in migraine with aura. Hum Genet. Apr;125(3):265-79. Epub 2009 Jan 17
  • Rakovic A, Stiller B, Djarmati A, Flaquer A, Freudenberg J, Toliat MR, Linnebank M, Kostic V, Lohmann K, Paus S, Nürnberg P, Kubisch C, Klein C, Wüllner U, Ramirez A (2009). Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease. Mov Disord. Feb 15;24(3):429-33

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Tobias Lamkemeyer

  • Biswas L, Biswas R, Nerz C, Ohlsen K, Schlag M, Schäfer T, Lamkemeyer T, Ziebandt AK, Hantke K, Rosenstein R, Götz F (2009). Role of the twin-arginine translocation pathway in Staphylococcus. J Bacteriol. Oct;191(19):5921-9. Epub 2009 Jul 24
  • Pirow R, Buchen I, Richter M, Allmer C, Nunes F, Günsel A, Heikens W, Lamkemeyer T, von Reumont BM, Hetz SK (2009). Cationic composition and acid-base state of the extracellular fluid, and specific buffer value of hemoglobin from the branchiopod crustacean Triops cancriformis. J Comp Physiol B. Apr;179(3):369-81. Epub 2008 Dec 9
  • Saleem M, Lamkemeyer T, Schützenmeister A, Fladerer C, Piepho HP, Nordheim A, Hochholdinger F. (2009). Tissue specific control of the maize (Zea mays L.) embryo, cortical parenchyma, and stele proteomes by RUM1 which regulates seminal and lateral root initiation. J Proteome Res. May;8(5):2285-97
  • Schwerin S, Zeis B, Lamkemeyer T, Paul RJ, Koch M, Madlung J, Fladerer C, Pirow R (2009). Acclimatory responses of the Daphnia pulex proteome to environmental changes. II. Chronic exposure to different temperatures (10 and 20 degrees C) mainly affects protein metabolism. BMC Physiol. Apr 21;9:8
  • Sprossmann F, Pankert P, Sausbier U, Wirth A, Zhou XB, Madlung J, Zhao H, Bucurenciu I, Jakob A, Lamkemeyer T, Neuhuber W, Offermanns S, Shipston MJ, Korth M, Nordheim A, Ruth P, Sausbier M (2009). Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder. FEBS J. Mar;276(6):1680-97. Epub 2008 Feb 12
  • Zeis B, Lamkemeyer T, Paul RJ, Nunes F, Schwerin S, Koch M, Schütz W, Madlung J, Fladerer C, Pirow R (2009). Acclimatory responses of the Daphnia pulex proteome to environmental changes. I. Chronic exposure to hypoxia affects the oxygen transport system and carbohydrate metabolism. BMC Physiol. Apr 21;9:7

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Michael Lammers

  • Price AJ, Marzetta F, Lammers M, Ylinen LM, Schaller T, Wilson SJ, Towers GJ, James LC (2009). Active site remodeling switches HIV specificity of antiretroviral TRIMCyp. Nat Struct Mol Biol. Oct;16(10):1036-42. Epub 2009 Sep 20

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Thomas Langer

  • Augustin S, Gerdes F, Lee S, Tsai FT, Langer T, Tatsuta T (2009). An intersub­unit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell. 35, 574-585
  • Ehses S, Raschke I, Mancuso G, Bernacchia A, Geimer S, Tondera D, Marti­nou JC, Westermann B, Rugarli EI, Langer T (2009). Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J Cell Biol. 187, 1023-1036
  • Graef M, Langer T, Engmann T (2009). The recognition of substrates by AAA proteases in mitochondria. In: ATP-dependent proteases. Ed.: Eva Kutejová. Research Signpost, Kerala, India. 179-195
  • Koppen M, Bonn F, Ehses S, Langer T (2009). Autocatalytic processing of m-AAA protease subunits in mitochondria. Mol Biol Cell. 20, 4216-4224
  • Merkwirth C, Langer T (2009). Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta. 1793, 27-32
  • Osman C, Haag M, Potting C, Rodenfels J, Dip PV, Wieland FT, Brügger B, Westermann B, Langer T (2009). The genetic interactome of prohibitins: coordi­nated control of cardiolipin and phosphatidylethanolamine by conserved regula­tors in mitochondria. J Cell Biol. 184, 583-596
  • Osman C, Merkwirth C, Langer T (2009). Prohibitins and the functional com­part­mentalization of mitochondrial membranes. J Cell Science. 122, 3823-3820
  • Tatsuta T, Langer T (2009). AAA proteases in mitochondria: diverse functions of mem­brane-bound proteolytic machines. Res Microbiol. 160, 711-717
  • Tondera D, Grandemange S, Jourdain A, Karbowski M, Mattenberger Y, Herzig S, Da Cruz S, Clerc P, Raschke I, Merkwirth C, Ehses S, Krause F, Chan DC, Alexander C, Bauer C, Youle R, Langer T, Martinou JC (2009). SLP-2 is required for stress-induced mitochondrial hyperfusion. EMBO J. 28, 1589-1600

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Nils-Göran Larsson

  • Aydin J, Andersson DC, Hänninen SL, Wredenberg A, Tavi P, Park CB, Larsson NG, Bruton JD, Westerblad H (2009). Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy. Hum Mol Genet. Jan 15;18(2):278-88. Epub 2008 Oct 22
  • Baranowska I, Jäderlund KH, Nennesmo I, Holmqvist E, Heidrich N, Larsson NG, Andersson G, Wagner EG, Hedhammar A, Wibom R, Andersson L (2009). Sensory ataxic neuropathy in golden retriever dogs is caused by a deletion in the mitochondrial tRNATyr gene. PLoS Genet. May;5(5):e1000499. Epub 2009 May 29
  • Edgar D, Shabalina I, Camara Y, Wredenberg A, Calvaruso MA, Nijtmans L, Nedergaard J, Cannon B, Larsson NG, Trifunovic A (2009). Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. Cell Metab. Aug;10(2):131-8
  • Falkenberg M, Larsson NG (2009). Structure casts light on mtDNA replication. Cell. Oct 16;139(2):231-3
  • Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Björklund A, Ichinose H, Perlmann T (2009). Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci. Dec 16;29(50):15923-32
  • Metodiev MD, Lesko N, Park CB, Cámara Y, Shi Y, Wibom R, Hultenby K, Gustafsson CM, Larsson NG (2009). Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome. Cell Metab. Apr;9(4):386-97
  • Naess K, Freyer C, Bruhn H, Wibom R, Malm G, Nennesmo I, von Döbeln U, Larsson NG (2009). MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome. Biochim Biophys Acta. May;1787(5):484-90. Epub 2008 Dec 6
  • Pellegrini M, Asin-Cayuela J, Erdjument-Bromage H, Tempst P, Larsson NG, Gustafsson CM (2009). MTERF2 is a nucleoid component in mammalian mitochondria. Biochim Biophys Acta. May;1787(5):296-302. Epub 2009 Feb 3

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Ivan Matic 

  • Andersen JS, Matic I, Vertegaal AC (2009). Identification of SUMO target proteins by quantitative proteomics. Methods in molecular biology. 2009, 497, 19-31
  • Cox J, Matic I, Hilger M, Nagaraj N, Selbach M, Olsen JV, Mann M (2009). A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics. Nature protocols. 2009, 4, (5), 698-705
  • Golebiowski F, Matic I, Tatham MH, Cole C, Yin Y, Nakamura A, Cox J, Barton GJ, Mann M, Hay RT (2009). System-wide changes to SUMO modifications in response to heat shock. Science signaling. 2009, 2, (72), ra24

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Carien M. Niessen

  • Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B (2009). Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. May;11(5):604-15. Epub 2009 Apr 12
  • Kayserili H, Uz E, Niessen C, Vargel I, Alanay Y, Tuncbilek G, Yigit G, Uyguner O, Candan S, Okur H, Kaygin S, Balci S, Mavili E, Alikasifoglu M, Haase I, Wollnik B, Akarsu NA (2009). ALX4 dysfunction disrupts craniofacial and epidermal development. Hum Mol Genet. Nov 15;18(22):4357-66. Epub 2009 Aug 19
  • Michels C, Aghdam SY, Niessen CM (2009). Cadherin-mediated regulation of tight junctions in stratifying epithelia. Ann N Y Acad Sci. May;1165:163-8
  • Michels C, Buchta T, Bloch W, Krieg T, Niessen CM (2009). Classical cadherins regulate desmosome formation. J Invest Dermatol. Aug;129(8):2072-5. Epub 2009 Mar 5
  • Seifert K, Ibrahim H, Stodtmeister T, Winklbauer R, Niessen CM (2009). An adhesion-independent, aPKC-dependent function for cadherins in morphogenetic movements. J Cell Sci. Jul 15;122(Pt 14):2514-23. Epub 2009 Jun 23

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Angelika A. Noegel

  • Blau-Wasser R, Euteneuer U, Xiong H, Gassen B, Schleicher M, Noegel AA (2009). CP250, a novel acidic coiled-coil protein of the Dictyostelium centrosome, affects growth, chemotaxis, and the nuclear envelope. Mol Biol Cell. Oct;20(20):4348-61. Epub 2009 Aug 19
  • Dawe HR, Adams M, Wheway G, Szymanska K, Logan CV, Noegel AA, Gull K, Johnson CA (2009). Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci. Aug 1;122(Pt 15):2716-26. Epub 2009 Jul 13
  • Lang PA, Kasinathan RS, Brand VB, Duranton C, Lang C, Koka S, Shumilina E, Kempe DS, Tanneur V, Akel A, Lang KS, Foller M, Kun JF, Kremsner PG, Wesselborg S, Laufer S, Clemen CS, Herr C, Noegel AA, Wieder T, Gulbins E, Lang F, Huber SM (2009). Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cell Physiol Biochem. 24(5-6):415-28. Epub 2009 Nov 4
  • Olins AL, Hoang TV, Zwerger M, Herrmann H, Zentgraf H, Noegel AA, Karakesisoglou I, Hodzic D, Olins DE (2009). The LINC-less granulocyte nucleus. Eur J Cell Biol. Apr;88(4):203-14. Epub 2008 Nov 18
  • Sultana H, Neelakanta G, Eichinger L, Rivero F, Noegel AA (2009). Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in Dictyostelium. Exp Cell Res. Jan 15;315(2):127-40. Epub 2008 Oct 31
  • Xavier CP, Rastetter RH, Stumpf M, Rosentreter A, Müller R, Reimann J, Cornfine S, Linder S, van Vliet V, Hofmann A, Morgan RO, Fernandez MP, Schröder R, Noegel AA, Clemen CS (2009). Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle. J Mol Biol. Oct 23;393(2):287-99. Epub 2009 Aug 3

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Peter Nürnberg

  • Chung BD, Kayserili H, Ai M, Freudenberg J, Uzümcü A, Uyguner O, Bartels CF, Höning S, Ramirez A, Hanisch FG, Nürnberg G, Nürnberg P, Warman ML, Wollnik B, Kubisch C, Netzer C (2009). A mutation in the signal sequence of LRP5 in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeats. Hum Mutat. Apr;30(4):641-8
  • Dathe K, Kjaer KW, Brehm A, Meinecke P, Nürnberg P, Neto JC, Brunoni D, Tommerup N, Ott CE, Klopocki E, Seemann P, Mundlos S (2009). Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2. Am J Hum Genet. Apr;84(4):483-92. Epub 2009 Mar 26
  • El-Harith el-HA, Roesl C, Ballmaier M, Germeshausen M, Frye-Boukhriss H, von Neuhoff N, Becker C, Nürnberg G, Nürnberg P, Ahmed MA, Hübener J, Schmidtke J, Welte K, Stuhrmann M (2009). Familial thrombocytosis caused by the novel germ-line mutation p.Pro106Leu in the MPL gene. Br J Haematol. Jan;144(2):185-94. Epub 2008 Nov 19
  • Hansen L, Mikkelsen A, Nürnberg P, Nürnberg G, Anjum I, Eiberg H, Rosenberg T (2009). Comprehensive mutational screening in a cohort of Danish families with hereditary congenital cataract. 
    Invest Ophthalmol Vis Sci. Jul;50(7):3291-303. Epub 2009 Jan 31
  • Hassel D, Dahme T, Erdmann J, Meder B, Huge A, Stoll M, Just S, Hess A, Ehlermann P, Weichenhan D, Grimmler M, Liptau H, Hetzer R, Regitz-Zagrosek V, Fischer C, Nürnberg P, Schunkert H, Katus HA, Rottbauer W (2009). Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nat Med. Nov;15(11):1281-8. Epub 2009 Nov 1
  • Heinz-Erian P, Müller T, Krabichler B, Schranz M, Becker C, Rüschendorf F, Nürnberg P, Rossier B, Vujic M, Booth IW, Holmberg C, Wijmenga C, Grigelioniene G, Kneepkens CM, Rosipal S, Mistrik M, Kappler M, Michaud L, Dóczy LC, Siu VM, Krantz M, Zoller H, Utermann G, Janecke AR (2009). Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea. Am J Hum Genet. Feb;84(2):188-96. Epub 2009 Jan 29
  • Helbig I, Mefford HC, Sharp AJ, Guipponi M, Fichera M, Franke A, Muhle H, de Kovel C, Baker C, von Spiczak S, Kron KL, Steinich I, Kleefuss-Lie AA, Leu C, Gaus V, Schmitz B, Klein KM, Reif PS, Rosenow F, Weber Y, Lerche H, Zimprich F, Urak L, Fuchs K, Feucht M, Genton P, Thomas P, Visscher F, de Haan GJ, Møller RS, Hjalgrim H, Luciano D, Wittig M, Nothnagel M, Elger CE, Nürnberg P, Romano C, Malafosse A, Koeleman BP, Lindhout D, Stephani U, Schreiber S, Eichler EE, Sander T (2009). 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet. Feb;41(2):160-2. Epub 2009 Jan 11
  • Henneke M, Diekmann S, Ohlenbusch A, Kaiser J, Engelbrecht V, Kohlschütter A, Krätzner R, Madruga-Garrido M, Mayer M, Opitz L, Rodriguez D, Rüschendorf F, Schumacher J, Thiele H, Thoms S, Steinfeld R, Nürnberg P, Gärtner J (2009). RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection. Nat Genet. Jul;41(7):773-5. Epub 2009 Jun 14
  • Hildebrandt F, Heeringa SF, Rüschendorf F, Attanasio M, Nürnberg G, Becker C, Seelow D, Huebner N, Chernin G, Vlangos CN, Zhou W, O'Toole JF, Hoskins BE, Wolf MT, Hinkes BG, Chaib H, Ashraf S, Schoeb DS, Ovunc B, Allen SJ, Vega-Warner V, Wise E, Harville HM, Lyons RH, Washburn J, Macdonald J, Nürnberg P, Otto EA (2009). A systematic approach to mapping recessive disease genes in individuals from outbred populations. PLoS Genet. Jan;5(1):e1000353. Epub 2009 Jan 23
  • Hoffmann K, Planitz C, Rüschendorf F, Müller-Myhsok B, Stassen HH, Lucke B, Mattheisen M, Stumvoll M, Bochmann R, Zschornack M, Wienker TF, Nürnberg P, Reis A, Luft FC, Lindner TH (2009). A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany. J Hypertens. May;27(5):983-90
  • Iseri SU, Osborne RJ, Farrall M, Wyatt AW, Mirza G, Nürnberg G, Kluck C, Herbert H, Martin A, Hussain MS, Collin JR, Lathrop M, Nürnberg P, Ragoussis J, Ragge NK (2009). Seeing clearly: the dominant and recessive nature of FOXE3 in eye developmental anomalies. Hum Mutat. Oct;30(10):1378-86
  • Karsak M, Malkin I, Toliat MR, Kubisch C, Nürnberg P, Zimmer A, Livshits G (2009). The cannabinoid receptor type 2 (CNR2) gene is associated with hand bone strength phenotypes in an ethnically homogeneous family sample. Hum Genet. Nov;126(5):629-36. Epub 2009 Jun 30
  • Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nürnberg G, Nürnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hübner CA (2009). Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy. Nat Genet. Nov;41(11):1179-81. Epub 2009 Oct 18
  • Loges NT, Olbrich H, Becker-Heck A, Häffner K, Heer A, Reinhard C, Schmidts M, Kispert A, Zariwala MA, Leigh MW, Knowles MR, Zentgraf H, Seithe H, Nürnberg G, Nürnberg P, Reinhardt R, Omran H (2009). Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Am J Hum Genet. Dec;85(6):883-9
  • Muhammad F, Mahmood Baig S, Hansen L, Sajid Hussain M, Anjum Inayat I, Aslam M, Anver Qureshi J, Toilat M, Kirst E, Wajid M, Nürnberg P, Eiberg H, Tommerup N, Kjaer KW (2009). Compound heterozygous ASPM mutations in Pakistani MCPH families. Am J Med Genet A. May;149A(5):926-30
  • Lu TT, Lao O, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Nielsen F, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Ruether A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Kayser M, Krawczak M (2009). An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population. Eur J Hum Genet. Jul;17(7):967-75. Epub 2009 Jan 21
  • Mégarbané A, Slim R, Nürnberg G, Ebermann I, Nürnberg P, Bolz HJ (2009). A novel VPS13B mutation in two brothers with Cohen syndrome, cutis verticis gyrata and sensorineural deafness. Eur J Hum Genet. Aug;17(8):1076-9. Epub 2009 Feb 4
  • Metherell LA, Naville D, Halaby G, Begeot M, Huebner A, Nürnberg G, Nürnberg P, Green J, Tomlinson JW, Krone NP, Lin L, Racine M, Berney DM, Achermann JC, Arlt W, Clark AJ (2009). Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency. J Clin Endocrinol Metab. Oct;94(10):3865-71. Epub 2009 Sep 22
  • Puk O, Esposito I, Söker T, Löster J, Budde B, Nürnberg P, Michel-Soewarto D, Fuchs H, Wolf E, Hrabé de Angelis M, Graw J (2009). A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease? Invest Ophthalmol Vis Sci. Sep;50(9):4311-8. Epub 2009 Apr 30
  • Rakovic A, Stiller B, Djarmati A, Flaquer A, Freudenberg J, Toliat MR, Linnebank M, Kostic V, Lohmann K, Paus S, Nürnberg P, Kubisch C, Klein C, Wüllner U, Ramirez A (2009). Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease. Mov Disord. Feb 15;24(3):429-33
  • Reversade B, Escande-Beillard N, Dimopoulou A, Fischer B, Chng SC, Li Y, Shboul M, Tham PY, Kayserili H, Al-Gazali L, Shahwan M, Brancati F, Lee H, O'Connor BD, Schmidt-von Kegler M, Merriman B, Nelson SF, Masri A, Alkazaleh F, Guerra D, Ferrari P, Nanda A, Rajab A, Markie D, Gray M, Nelson J, Grix A, Sommer A, Savarirayan R, Janecke AR, Steichen E, Sillence D, Hausser I, Budde B, Nürnberg G, Nürnberg P, Seemann P, Kunkel D, Zambruno G, Dallapiccola B, Schuelke M, Robertson S, Hamamy H, Wollnik B, Van Maldergem L, Mundlos S, Kornak U (2009). Mutations in PYCR1 cause cutis laxa with progeroid features. Nat Genet. Sep;41(9):1016-21. Epub 2009 Aug 2
  • Rutsch F, Gailus S, Miousse IR, Suormala T, Sagné C, Toliat MR, Nürnberg G, Wittkampf T, Buers I, Sharifi A, Stucki M, Becker C, Baumgartner M, Robenek H, Marquardt T, Höhne W, Gasnier B, Rosenblatt DS, Fowler B, Nürnberg P (2009). Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism. Nat Genet. Feb;41(2):234-9. Epub 2009 Jan 11
  • Seelow D, Schuelke M, Hildebrandt F, Nürnberg P (2009). HomozygosityMapper--an interactive approach to homozygosity mapping. Nucleic Acids Res. Jul 1;37(Web Server issue):W593-9. Epub 2009 May 21
  • Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M (2009). X chromosomal variation is associated with slow progression to AIDS in HIV-1-infected women. Am J Hum Genet. Aug;85(2):228-39
  • Todt U, Netzer C, Toliat M, Heinze A, Goebel I, Nürnberg P, Göbel H, Freudenberg J, Kubisch C (2009). New genetic evidence for involvement of the dopamine system in migraine with aura. Hum Genet. Apr;125(3):265-79. Epub 2009 Jan 17
  • Twigg SR, Versnel SL, Nürnberg G, Lees MM, Bhat M, Hammond P, Hennekam RC, Hoogeboom AJ, Hurst JA, Johnson D, Robinson AA, Scambler PJ, Gerrelli D, Nürnberg P, Mathijssen IM, Wilkie AO (2009). Frontorhiny, a distinctive presentation of frontonasal dysplasia caused by recessive mutations in the ALX3 homeobox gene. Am J Hum Genet. May;84(5):698-705. Epub 2009 Apr 30

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Linda Partridge

  • Augustin H, Partridge L (2009). Invertebrate models of age-related muscle degeneration. Biochim Biophys Acta. Oct;1790(10):1084-94. Epub 2009 Jun 27. Review
  • Broughton S, Partridge L (2009). Insulin/IGF-like signalling, the central nervous system and aging. Biochem J. Feb 15;418(1):1-12. Review
  • Grandison RC, Piper MD, Partridge L (2009). Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature. Dec 24;462(7276):1061-4. Epub 2009 Dec 2
  • Grandison RC, Wong R, Bass TM, Partridge L, Piper MD (2009). Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. PLoS One. ;4(1):e4067. Epub 2009 Jan 1
  • Humphrey DM, Toivonen JM, Giannakou M, Partridge L, Brand MD (2009). Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Exp Gerontol. May;44(5):316-27
  • Ikeya T, Broughton S, Alic N, Grandison R, Partridge L (2009). The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proc Biol Sci. Nov 7;276(1674):3799-807. Epub 2009 Aug 19
  • Iqbal A, Piper M, Faragher RG, Naughton DP, Partridge L, Ostler EL (2009). Chemical changes in aging Drosophila melanogaster. Age (Dordr). Dec;31(4):343-51
  • Partridge L (2009). Some highlights of research on aging with invertebrates, 2009. Aging Cell. Sep;8(5):509-13. Epub 2009 Jul 22
  • Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, Thomas G, Carling D, Okkenhaug K, Thornton JM, Partridge L, Gems D, Withers DJ (2009). Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science. Oct 2;326(5949):140-4. Erratum in: Science. 2011 Oct 7;334(6052):39
  • Slaidina M, Delanoue R, Gronke S, Partridge L, Léopold P (2009). A Drosophila insulin-like peptide promotes growth during nonfeeding states. Dev Cell. Dec;17(6):874-84
  • Toivonen JM, Gems D, Partridge L (2009). Longevity of Indy mutant Drosophila not attributable to Indy mutation. Proc Natl Acad Sci U S A. May 26;106(21):E53; author reply E54. Epub 2009 May 12
  • Toivonen JM, Partridge L (2009). Endocrine regulation of aging and reproduction in Drosophila. Mol Cell Endocrinol. Feb 5;299(1):39-50. Epub 2008 Jul 17. Review
  • Wong R, Piper MD, Wertheim B, Partridge L (2009). Quantification of food intake in Drosophila. PLoS One. Jun 26;4(6):e6063

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Manolis Pasparakis 

  • Bockhart V, Constantin CE, Häussler A, Wijnvoord N, Kanngiesser M, Myrczek T, Pickert G, Popp L, Sobotzik JM, Pasparakis M, Kuner R, Geisslinger G, Schultz C, Kress M, Tegeder I (2009). Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity. J Neurosci. 2009, 29(41):12919-29
  • De Lorenzi R, Gareus R, Fengler S, Pasparakis M (2009). GFP-p65 knock-in mice as a tool to study NF-kappaB dynamics in vivo. Genesis. 2009, 47(5):323-9
  • Derudder E, Cadera EJ, Vahl JC, Wang J, Fox CJ, Zha S, van Loo G, Pasparakis M, Schlissel MS, Schmidt-Supprian M, Rajewsky K (2009). Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals. Nat Immunol. 2009, 10(6):647-54
  • Marques R, Williams A, Eksmond U, Wullaert A, Killeen N, Pasparakis M, Kioussis D, Kassiotis G (2009). Generalized immune activation as a direct result of activated CD4+ T cell killing. J Biol. 2009, 8(10):93
  • Pasparakis M (2009). Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Nat Rev Immunol. 2009, 9(11):778-88
  • Sung MH, Salvatore L, De Lorenzi R, Indrawan A, Pasparakis M, Hager GL, Bianchi ME, Agresti A (2009). Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles. PLoS One. 2009, 4(9):e7163

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Mats Paulsson

  • Buchstein N, Hoffmann D, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA (2009). Alternative proteolytic processing of hepatocyte growth factor during wound repair. Am J Pathol. Jun;174(6):2116-28. Epub 2009 Apr 23
  • Ehlen HW, Sengle G, Klatt AR, Talke A, Müller S, Paulsson M, Wagener R (2009). Proteolytic processing causes extensive heterogeneity of tissue matrilin forms. J Biol Chem. Aug 7;284(32):21545-56. Epub 2009 Jun 16
  • Gebauer JM, Keene DR, Olsen BR, Sorokin LM, Paulsson M, Wagener R (2009). Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment. Matrix Biol. Oct;28(8):456-62. Epub 2009 Aug 3
  • Klatt AR, Klinger G, Paul-Klausch B, Kühn G, Renno JH, Wagener R, Paulsson M, Schmidt J, Malchau G, Wielckens K (2009). Matrilin-3 activates the expression of osteoarthritis-associated genes in primary human chondrocytes. FEBS Lett. Nov 19;583(22):3611-7. Epub 2009 Oct 17
  • Malan D, Reppel M, Dobrowolski R, Roell W, Smyth N, Hescheler J, Paulsson M, Bloch W, Fleischmann BK (2009). Lack of laminin gamma1 in embryonic stem cell-derived cardiomyocytes causes inhomogeneous electrical spreading despite intact differentiation and function. Stem Cells. Jan;27(1):88-99
  • Smyth N, Odenthal U, Merkl B, Paulsson M (2009). Eukaryotic expression and purification of recombinant extracellular matrix proteins carrying the strep II tag. Methods Mol Biol. 2009;522:63-72
  • Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J (2009). VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding. Thromb Haemost. Jun;101(6):1044-50
  • Wagener R, Gara SK, Kobbe B, Paulsson M, Zaucke F (2009). The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5' part of the split COL6A4 gene. Matrix Biol. Jul;28(6):307-10. Epub 2009 May 30

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Alvaro Rada-Iglesias

  • Andersson R, Enroth S, Rada-Iglesias A, Wadelius C, Komorowski J (2009). Nucleosomes are well positioned in exons and carry characteristic histone modifications. Genome Res. Oct;19(10):1732-41
  • Ameur A, Rada-Iglesias A, Komorowski J, Wadelius C (2009). Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP. Nucleic Acids ResJul;37(12):e85. 
  • Rada-Iglesias A, Enroth S, Andersson R, Wanders A, Påhlman L, Komorowski J, Wadelius C (2009). Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation. Epigenetics. Feb 16;4(2):107-13

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H. Christian Reinhardt

  • Jiang H, Reinhardt HC, Bartkova J, Tommiska J, Blomqvist C, Nevanlinna H, Bartek J, Yaffe MB, Hemann MT (2009). The combined status of ATM and p53 link tumor development with therapeutic response. Genes Dev. Aug 15;23(16):1895-909. Epub 2009 Jul 16
  • Reinhardt HC, Jiang H, Hemann MT, Yaffe MB (2009). Exploiting synthetic lethal interactions for targeted cancer therapy. Cell Cycle. Oct 1;8(19):3112-9. Review
  • Reinhardt HC, Yaffe MB (2009). Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Curr Opin Cell Biol. Apr;21(2):245-55. Epub 2009 Feb 21. Review

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Nirmal Robinson

  • Albaghdadi H, Robinson N, Dudani R, Krishnan L, Sad S (2009). Selectively reduced intracellular proliferation of Salmonella Typhimurium within antigen-presenting cells limits antigen-presentation and development of a rapid CD8 T cell response. Journal of Immunology. 183(6):3778-87

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Elena I. Rugarli

  • Ehses S, Raschke I, Mancuso G, Bernacchia A, Geimer S, Tondera D, Martinou JC, Westermann B, Rugarli EI, Langer T (2009). Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J Cell Biol. Dec 28;187(7):1023-36
  • Martinelli P, La Mattina V, Bernacchia A, Magnoni R, Cerri F, Cox G, Quattrini A, Casari G, Rugarli EI (2009). Genetic interaction between the m-AAA protease isoenzymes reveals novel roles in cerebellar degeneration. Hum Mol Genet. Jun 1;18(11):2001-13. Epub 2009 Mar 16
  • Riano E, Martignoni M, Mancuso G, Cartelli D, Crippa F, Toldo I, Siciliano G, Di Bella D, Taroni F, Bassi MT, Cappelletti G, Rugarli EI (2009). Pleiotropic effects of spastin on neurite growth depending on expression levels. J Neurochem. Mar;108(5):1277-88. Epub 2009 Jan 29

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Markus Schubert

  • Freude S, Hettich MM, Schumann C, Stöhr O, Koch L, Köhler C, Udelhoven M, Leeser U, Müller M, Kubota N, Kadowaki T, Krone W, Schröder H, Brüning JC, Schubert M (2009). Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J. Oct;23(10):3315-24. Epub 2009 Jun 1
  • Jockenhövel F, Minnemann T, Schubert M, Freude S, Hübler D, Schumann C, Christoph A, Gooren L, Ernst M (2009). Timetable of effects of testosterone administration to hypogonadal men on variables of sex and mood. Aging Male. Dec;12(4):113-8

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Björn Schumacher

  • Garinis GA, Schumacher B (2009). Transcription-blocking DNA damage in aging and longevity. Cell Cycle. Jul 15;8(14):2134-5. Epub 2009 Jul 20
  • Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B (2009). Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity. Nat Cell Biol. May;11(5):604-15. Epub 2009 Apr 12
  • Schumacher B (2009). Transcription-blocking DNA damage in aging: a mechanism for hormesis. Bioessays. Dec;31(12):1347-56. Review
  • Schumacher B, Hoeijmakers JH, Garinis GA (2009). Sealing the gap between nuclear DNA damage and longevity. Mol Cell Endocrinol. Feb 5;299(1):112-7. Epub 2008 Nov 5. Review. Erratum in: Mol Cell Endocrinol. 2009 May 6;303(1-2):107

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Günter Schwarz

  • Kolmos E, Nowak M, Werner M, Fischer K, Schwarz G, Mathews S, Schoof H, Nagy F, Bujnicki JM, Davis SJ (2009). Integrating ELF4 into the circadian system through combined structural and functional studies. HFSP J. Oct;3(5):350-66. Epub 2009 Oct 22
  • Eichler SA, Förstera B, Smolinsky B, Jüttner R, Lehmann TN, Fähling M, Schwarz G, Legendre P, Meier JC (2009). Splice-specific roles of glycine recepror ?3 in the hippocampus. Eur. J. Neursci. 3: 1077-91
  • Schwarz G, Mendel RR, Ribbe WM (2009). Molybdenum cofactors, enzymes and pathways. Nature. 460: 839-47

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Philipp Steven

  • Steven P, Gebert A (2009). Conjunctiva-associated lymphoid tissue - current knowledge, animal models and experimental prospects. Ophthalmic Res. 2009;42(1):2-8. Epub 2009 May 28. Review

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Wilhelm Stoffel

  • Dours-Zimmermann MT, Maurer K, Rauch U, Stoffel W, Fässler R, Zimmermann DR (2009). Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. J Neurosci. Jun 17;29(24):7731-42

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Peter Tessarz

  • Tessarz P, Schwarz M, Mogk A, Bukau B (2009). The yeast AAA+ chaperone Hsp104 is part of a network that links the actin cytoskeleton with the inheritance of damaged proteins. Mol Cell Biol. 29, 3738–3745

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Mathias Treier

  • Uhlenhaut NH, Jakob S, Anlag K, Eisenberger T, Sekido R, Kress J, Treier AC, Klugmann C, Klasen C, Holter NI, Riethmacher D, Schütz G, Cooney AJ, Lovell-Badge R, Treier M (2009). Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell. Dec 11;139(6):1130-42
  • Storm R, Cholewa-Waclaw J, Reuter K, Bröhl D, Sieber M, Treier M, Müller T, Birchmeier C (2009). The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei. Development. Jan;136(2):295-305. Epub 2008 Dec 15

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Aleksandra Trifunovic

  • Bratic I, Hench J, Henriksson J, Antebi A, Burglin T, Trifunovic A (2009). Mitochondrial DNA levels, but not mitochondrial DNA polymerase, are essential for C. elegans development. Nucleic Acids Res. 37(6):1817-28
  • Edgar D, Shabalina I, Camara Y, Wredenberg A, Calvaruso MA, Nijtmans  L, Nedergaard J, Cannon B, Larsson NG,  Trifunovic A (2009). Random point mutations with major effects on protein coding genes drive premature ageing in mtDNA mutator mice. Cell Metab. 10:131-138

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Clemens Wendtner

  • Baumert J, Schmidt M, Giehl KA, Volkenandt M, Plewig G, Wendtner C, Schmid-Wendtner MH (2009). Time trends in tumour thickness vary in subgroups: analysis of 6475 patients by age, tumour site and melanoma subtype. Melanoma Res. Feb;19(1):24-30
  • Eichhorst BF, Busch R, Stilgenbauer S, Stauch M, Bergmann MA, Ritgen M, Kranzhöfer N, Rohrberg R, Söling U, Burkhard O, Westermann A, Goede V, Schweighofer CD, Fischer K, Fink AM, Wendtner CM, Brittinger G, Döhner H, Emmerich B, Hallek M (2009). German CLL Study Group (GCLLSG). First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia. Blood. Oct 15;114(16):3382-91. Epub 2009 Jul 15
  • Kalaycio M, Wendtner CM (2009). Review: what causes neurotoxicity after exposure to purine analogs? Clin Adv Hematol Oncol. Nov;7(11):745-6. Review
  • Pallasch CP, Wendtner CM (2009). Overexpression of the Fas-inhibitory molecule TOSO: a novel antiapoptotic factor in chronic lymphocytic leukemia. Leuk Lymphoma. Mar;50(3):498-501. Review
  • Schmid-Wendtner MH, Wendtner CM (2009). Intensified inflammatory reaction of actinic keratoses after single application of topical 5-fluorouracil in a patient treated with nilotinib for chronic myeloid leukemia. Dermatology. ;219(4):341-3. Epub 2009 May 22

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Sara Wickström

  • Lange A, Wickström SA, Jakobson M, Zent R, Sainio K, Fässler R (2009). Integrin-linked kinase is an adaptor with essential functions during mouse development.  Nature. 461, 1002-1006
  • Legate KR, Wickström SA, Fässler R (2009). Genetic and cell biological analysis of integrin inside-out signaling. Genes Dev. 23, 397-418
  • Montanez E, Wickström SA, Altstätter J, Chu H, Fässler R (2009). α-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling. EMBO J. 28, 3132 - 3144
  • Wickström SA, Fässler R (2009). Integrins anchor the invasive machinery. Dev Cell. 17, 158-160

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Rudolf J. Wiesner

  • Gekeler J, Zsurka G, Kunz WS, Preuss SF, Klussmann JP, Guntinas-Lichius O, Wiesner RJ (2009). Clonal expansion of different mtDNA variants without selective advantage in solid tumors. Mutat Res. Mar 9;662(1-2):28-32. Epub 2008 Dec 9
  • Hornig-Do HT, Günther G, Bust M, Lehnartz P, Bosio A, Wiesner RJ (2009). Isolation of functional pure mitochondria by superparamagnetic microbeads. Anal Biochem. Jun 1;389(1):1-5. Epub 2009 Mar 11

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Bernd Wollnik

  • Baş F, Kayserili H, Darendeliler F, Uyguner O, Günöz H, Yüksel Apak M, Atalar F, Bundak R, Wilson RC, New MI, Wollnik B, Saka N (2009). CYP21A2 Gene Mutations in Congenital Adrenal Hyperplasia: Genotype-phenotype correlation in Turkish children. J Clin Res Pediatr Endocrinol. Mar;1(3):116-28. Epub 2009 Feb 2
  • Chung BD, Kayserili H, Ai M, Freudenberg J, Uzümcü A, Uyguner O, Bartels CF, Höning S, Ramirez A, Hanisch FG, Nürnberg G, Nürnberg P, Warman ML, Wollnik B, Kubisch C, Netzer C (2009). A mutation in the signal sequence of LRP5 in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeats. Hum Mutat. Apr;30(4):641-8
  • Durmaz B, Wollnik B, Cogulu O, Li Y, Tekgul H, Hazan F, Ozkinay F (2009). Pontocerebellar hypoplasia type III (CLAM): extended phenotype and novel molecular findings. J Neurol. Mar;256(3):416-9. Epub 2009 Mar 14
  • Kayserili H, Uz E, Niessen C, Vargel I, Alanay Y, Tuncbilek G, Yigit G, Uyguner O, Candan S, Okur H, Kaygin S, Balci S, Mavili E, Alikasifoglu M, Haase I, Wollnik B, Akarsu NA (2009). ALX4 dysfunction disrupts craniofacial and epidermal development. Hum Mol Genet. Nov 15;18(22):4357-66. Epub 2009 Aug 19
  • Nahum S, Pasternack SM, Pforr J, Indelman M, Wollnik B, Bergman R, Nöthen MM, König A, Khamaysi Z, Betz RC, Sprecher E (2009). A large duplication in LIPH underlies autosomal recessive hypotrichosis simplex in four Middle Eastern families. Arch Dermatol Res. Jun;301(5):391-3. Epub 2008 Sep 27
  • Reversade B, Escande-Beillard N, Dimopoulou A, Fischer B, Chng SC, Li Y, Shboul M, Tham PY, Kayserili H, Al-Gazali L, Shahwan M, Brancati F, Lee H, O'Connor BD, Schmidt-von Kegler M, Merriman B, Nelson SF, Masri A, Alkazaleh F, Guerra D, Ferrari P, Nanda A, Rajab A, Markie D, Gray M, Nelson J, Grix A, Sommer A, Savarirayan R, Janecke AR, Steichen E, Sillence D, Hausser I, Budde B, Nürnberg G, Nürnberg P, Seemann P, Kunkel D, Zambruno G, Dallapiccola B, Schuelke M, Robertson S, Hamamy H, Wollnik B, Van Maldergem L, Mundlos S, Kornak U (2009). Mutations in PYCR1 cause cutis laxa with progeroid features. Nat Genet. Sep;41(9):1016-21. Epub 2009 Aug 2
  • Valencia M, Lapunzina P, Lim D, Zannolli R, Bartholdi D, Wollnik B, Al-Ajlouni O, Eid SS, Cox H, Buoni S, Hayek J, Martinez-Frias ML, Antonio PA, Temtamy S, Aglan M, Goodship JA, Ruiz-Perez VL (2009). Widening the mutation spectrum of EVC and EVCectopic expression of Weyer variants in NIH 3T3 fibroblasts disrupts Hedgehog signaling. Hum Mutat. Dec;30(12):1667-75

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Thomas Wunderlich

  • Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT (2009). Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity. J Neurosci. Sep 16;29(37):11582-93
  • Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM (2009). Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes. J Clin Invest. Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8
  • Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC (2009). MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. Oct;10(4):249-59
  • Remedi MS, Kurata HT, Scott A, Wunderlich FT, Rother E, Kleinridders A, Tong A, Brüning JC, Koster JC, Nichols CG (2009). Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus. Cell Metab. Feb;9(2):140-51
  • Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J (2009). VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding. Thromb Haemost. Jun;101(6):1044-50
  • Yazdanpanah B, Wiegmann K, Tchikov V, Krut O, Pongratz C, Schramm M, Kleinridders A, Wunderlich T, Kashkar H, Utermöhlen O, Brüning JC, Schütze S, Krönke M (2009). Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. Aug 27;460(7259):1159-63. Epub 2009 Jul 29

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