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Publications 2013

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Adam Antebi

  • Adams P, Antebi A, Cuervo AM, Kennedy B, Sedivy J (2013). Aging Cell in 2012. Editorial. Aging Cell. 12, 1
  • Antebi A (2013a). Regulation of longevity by the reproductive system. Experimental gerontology. 48, 596-602
  • Antebi A (2013b). Steroid regulation of C. elegans. diapause, developmental timing, and longevity. Curr Top Dev Biol 105, 181-212
  • Heestand BN, Shen Y, Liu W, Magner DB, Storm N, Meharg C, Habermann B, Antebi A (2013). Dietary restriction induced longevity is mediated by nuclear receptor NHR-62 in Caenorhabditis elegans. PLoS Genetics. 9, e1003651
  • Magner DB, Wollam J, Shen Y, Hoppe C, Li D, Latza C, Rottiers V, Hutter H, Antebi A (2013). The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans. Cell metabolism. 18, 212-224
  • Rossi M, Duan S, Jeong YT, Horn M, Saraf A, Florens L, Washburn MP, Antebi A, Pagano M (2013). Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF (Fbxo11) ubiquitin ligase. Mol Cell. 49, 1159-1166

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Thomas Benzing

  • Anderson M, Kim E, Hagmann H, Benzing T, Dryer S (2013). Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol. Am J Physiol Cell Physiol. 305: C276-89
  • Bartram M, Höhne M, Dafinger C, Völker L, Albersmeyer M, Heiss J, Göbel H, Brönneke H, Burst V, Liebau M, Benzing T, Schermer B, Müller R (2013). Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT). J Mol Med. 91: 739–48
  • Brinkkoetter P, Ising C, Benzing T (2013). The role of the podocyte in albumin filtration. Nat Rev Nephrol. 9: 328–36
  • Burst V, Pütsch F, Kubacki T, Völker L, Bartram M, Müller R, Gillis M, Kurschat C, Grundmann F, Müller-Ehmsen J, Benzing T, Teschner S (2013). Survival and distribution of injected haematopoietic stem cells in acute kidney injury. Nephrol Dial Transplant. 28: 1131–9
  • Er F, Nia A, Dopp H, Dahlem K, Caglayan E, Erdmann E, Gassanov N, Hellmich M, Burst V, Kubacki T, Benzing T (2013). Response to letter regarding article, “Ischemic preconditioning for prevention of contrast medium-induced nephropathy: randomized Pilot RenPro-Trial (Renal Protection Trial)”. Circulation. 127: e536
  • Frank V, Habbig S, Bartram M, Eisenberger T, Veenstra-Knol H, Decker C, Boorsma R, Göbel H, Nürnberg G, Griessmann A, Franke M, Borgal L, Kohli P, Völker L, Dötsch J, Nürnberg P, Benzing T, Bolz H, Johnson C, Gerkes E, Schermer B, Bergmann C (2013). Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. Hum Mol Genet. 22: 2177–85
  • Gharbi H, Fabretti F, Bharill P, Rinschen M, Brinkkötter S, Frommolt P, Burst V, Schermer B, Benzing T, Müller R (2013). Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. Aging Cell. 12: 593–603
  • Grundmann F, Witthus M, Göbel H, Kisner T, Siewert R, Benzing T, Kurschat C (2013). Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib. Clin Kidney J. 6: 327–329
  • Habbig S, Frank V, Bartram M, Goebel H, Benzing T, Schermer B, Bergmann C (2013). First evidence of NPHP9 null-mutations in humans resulting in renal-pancreato-hepatic dysplasia. Pediatr Nephrol. 28: 1539–1539
  • Hackl M, Burford J, Villanueva K, Lam L, Suszták K, Schermer B, Benzing T, Peti-Peterdi J (2013). Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med. 19: 1661–6
  • Höhne M, Ising C, Hagmann H, Völker L, Brähler S, Schermer B, Brinkkoetter P, Benzing T (2013). Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. Am J Pathol. 182: 332–8
  • Kim E, Anderson M, Wilson C, Hagmann H, Benzing T, Dryer S (2013). NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex. Am J Physiol Cell Physiol. 305: C960-71
  • Liebau M, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller R, Brodesser S, Brodesser S, Saleem M, Benzing T, Schermer B, Cybulla M, Kurschat C, Kurschat C (2013). Dysregulated autophagy contributes to podocyte damage in Fabry’s disease. PLoS ONE. 8: e63506
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze J, Roodbergen M, Hoeijmakers J, Schumacher B, Nürnberg P, Dollé M, Benzing T, Müller R, Kurschat C (2013). Transcriptional profiling reveals progeroid Ercc1(-/?) mice as a model system for glomerular aging. BMC Genomics. 14: 559
  • Schuster J, Moinzadeh P, Kurschat C, Benzing T, Krieg T, Weber M, Hunzelmann N (2013). Proteinuria in systemic sclerosis: reversal by ACE inhibition. Rheumatol Int. 33: 2225–30
  • Völker L, Schurek E, Rinschen M, Tax J, Schutte B, Lamkemeyer T, Ungrue D, Schermer B, Benzing T, Höhne M (2013). Characterization of a short isoform of the kidney protein podocin in human kidney. BMC Nephrol. 14: 102

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Matteo Bergami

  • Bergami M, Vignoli B, Motori E, Pifferi S, Zuccaro E, Menini A, Canossa M (2013). TrkB signaling directs the incorporation of newly-generated periglomerular cells in the adult olfactory bulb. J Neurosci. 33, 11464-11478
  • Deshpande A, Bergami M, Gahnem A, Conzelmann KK, Lepier A, Götz M, Berninger B (2013). Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb. Proc Natl Acad Sci U S A. 110, E1152-E1161
  • Motori E, Puyal J, Toni N, Ghanem A, Angeloni C, Malaguti M, Cantelli-Forti G, Berninger B, Conzelmann KK, Götz M, Winklhofer K, Hrelia S, Bergami M (2013). Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance. Cell Metab. 18, 844-859

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Andreas Beyer

  • Ackermann M, Sikora-Wohlfeld W, Beyer A (2013). Impact of natural genetic variation on gene expression dynamics. PLoS Genet. 9(6):e1003514
  • Biswas U, Wetzker C, Lange J, Christodoulou EG, Seifert M, Beyer A, Jessberger R (2013). Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. PLoS Genetics. 9(12):e1003985
  • Gunaratne J, Schmidt A, Quandt A, Neo SP, Saraç OS, Gracia T, Loguercio S, Ahrné E, Xia RL, Tan KH, Lössner C, Bähler J, Beyer A, Blackstock W, Aebersold R (2013). Extensive mass spectrometry-based analysis of the fission yeast proteome: the Schizosaccharomyces pombe PeptideAtlas. Molec. Cell. Prot. 12(6):1741-51
  • Lehtinen S, Marsellach FX, Codlin S, Schmidt A, Clément-Ziza M, Beyer A, Bähler J, Orengo C, Pancaldi V (2013). Stress induces remodelling of yeast interaction and co-expression networks. Molec. Biosyst. 9(7):1697-707
  • Picotti P, Clement-Ziza M, Lam H, Campbell DS, Schmidt A, Deutsch EW, Röst H, Sun Z, Rinner O, Reiter L, Shen Q, Michaelson JJ, Frei A, Alberti S, Kusebauch U, Wollscheid B, Moritz R, Beyer A, Aebersold R (2013). A complete mass spectrometric map for the analysis of the yeast proteome and its application to quantitative trait analysis. Nature. 494(7436):266-70
  • Sikora-Wohlfeld W, Ackermann M, Elefsinioti EG, Singaravelu K, Beyer A (2013). Assessing computational methods for transcription factor target gene identification based on ChIP-seq data. PLoS Comp. Biol. 9(11): e1003342

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Susanne Brodesser

  • Franko A, von Kleist-Retzow JC, Neschen S, Wu M, Schommers P, Böse M, Kunze A, Hartmann U, Sanchez-Lasheras C, Stoehr O, Huntgeburth M, Brodesser S, Irmler M, Beckers J, de Angelis MH, Paulsson M, Schubert M, Wiesner RJ (2013). Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. J Hepatol. Nov 28. pii: S0168-8278(13)00821-0. Doi: 10.1016/j.jhep.2013.11.020. Epub 2013 Nov 28
  • Liebau MC, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller RU, Brodesser S, Saleem MA, Benzing T, Schermer B, Cybulla M, Kurschat CE (2013) Dysregulated Autophagy Contributes to Podocyte Damage in Fabry's Disease. PLoS One. May 17;8(5):e63506. doi: 10.1371/journal.pone.0063506. Print 2013 
  • Eckl KM, Tidhar R, Thiele H, Oji V, Hausser I, Brodesser S, Preil ML, Onal-Akan A, Stock F, Müller D, Becker K, Casper R, Nürnberg G, Altmüller J, Nürnberg P, Traupe H, Futerman AH, Hennies HC (2013). Impaired Epidermal Ceramide Synthesis Causes Autosomal Recessive Congenital Ichthyosis and Reveals the Importance of Ceramide Acyl Chain Length. J Invest Dermatol. Apr 2. doi: 10.1038/jid.2013.153. Epub 2013 Apr 2 
  • Angelbeck-Schulze M, Stahl J, Brodesser S, Rohn K, Naim H, Hewicker-Trautwein M, Kietzmann M, Bäumer W, Mischke R (2013). Comparison of three different sampling methods for canine skin lipids.
    Vet Dermatol.
    Apr;24(2):233-e51. doi: 10.1111/vde.12015

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Jens Brüning

  • Gahete MD, Córdoba-Chacón J, Lin Q, Brüning JC, Kahn CR, Castaño JP, Christian H, Luque RM, Kineman RD (2013). Insulin and IGF-I Inhibit GH Synthesis and Release in Vitro and in Vivo by Separate Mechanisms. Endocrinology. 154: 2410 – 20
  • Gouni-Berthold I, Brüning JC, Berthold HK (2013). Novel Approaches to the Pharmacotherapy of Obesity. Curr Pharm Des. 2013;19(27):4938-52
  • Gruber S, Straub BK, Ackermann PJ, Wunderlich CM, Mauer J, Seeger JM, Büning H, Heukamp L, Kashkar H, Schirmacher P, Brüning JC, Wunderlich FT (2013). Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Rep. 4: 669-80
  • Günschmann C, Stachelscheid H, Akyüz MD, Schmitz A, Missero C, Brüning JC, Niessen CM (2013). Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. Dev Cell. 26: 176-87
  • Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, Franz T, Horvath TL, Rüther U, Jaffrey SR, Kloppenburg P, Brüning JC (2013). The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat Neurosci. Aug;16(8):1042-8
  • Karra E, O'Daly OG, Choudhury AI, Yousseif A, Millership S, Neary MT, Scott WR, Chandarana K, Manning S, Hess ME, Iwakura H, Akamizu T, Millet Q, Gelegen C, Drew ME, Rahman S, Emmanuel JJ, Williams SC, Rüther UU, Brüning JC, Withers DJ, Zelaya FO, Batterham RL (2013). A link between FTO, ghrelin, and impaired brain food-cue responsivity. J Clin Invest. 123: 3539-51
  • Kornfeld JW, Baitzel C, Könner AC, Nicholls HT, Vogt MC, Herrmanns K, Scheja L, Haumaitre C, Wolf AM, Knippschild U, Seibler J, Cereghini S, Heeren J, Stoffel M, Brüning JC (2013). Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature. 494: 111 - 5
  • Qiu X, Dowling AR, Marino JS, Faulkner LD, Bryant B, Brüning JC, Elias CF, Hill JW (2013). Delayed Puberty but Normal Fertility in Mice With Selective Deletion of Insulin Receptors From Kiss1 Cell. Endocrinology. 154: 1337 - 48
  • Steculorum SM, Vogt MC, Brüning JC (2013). Perinatal Programming of Metabolic Diseases: Role of Insulin in the Development of Hypothalamic Neurocircuits. Endocrinol Metab Clin North Am. 42: 149 - 164
  • Tovar S, Paeger L, Hess S, Morgan DA, Hausen AC, Brönneke HS, Hampel B, Ackermann PJ, Evers N, Büning H, Wunderlich FT, Rahmouni K, Kloppenburg P, Brüning JC (2013). K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metab. 18: 445-55

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Oliver A. Cornely

  • Arendrup MC, Boekhout T, Akova M, Meis JF, Cornely OA, Lortholary O, The ESCMID EFISG study group and ECMM, Arikan-Akdagli S, Cuenca-Estrella M, Dannaoui E, van Diepeningen AD, Groll AH, Guarro J, Guinea J, Hope W, Lackner M, Lagrou K, Lanternier F, Lass-Flörl C, Meletiadis J, Munoz P, Pagano L, Richardson MD, Roilides E, Tortorano AM, Ullmann AJ (2013). ESCMID/ECMM Joint Clinical Guideline for the Diagnosis and Management of Rare Invasive Yeast Infections. Clin Microbiol Infect. Sep 18
  • Cornely OA, Miller MA, Fantin BR, Mullane KM, Kean Y, Gorbach SL (2013). Reply to M.R. Green et al. J Clin Oncol. Dec 1;31(34):4379
  • Cornely OA, Miller MA, Fantin B, Mullane K, Kean Y, Gorbach S (2013). Resolution of Clostridium difficile-Associated Diarrhea in Patients With Cancer Treated With Fidaxomicin or Vancomycin. J Clin Oncol. May 28. 2013;31(19):2493-9
  • Farowski F, Cornely OA, Vehreschild JJ, Wiesen M, Steinbach A, Vehreschild MJ, Müller C (2013). Intracellular concentrations of anidulafungin in different compartments of the peripheral blood. Int J Antimicrob Agents. Apr;41(4):379-82
  • Glockner A, Cornely OA (2013). Invasive candidiasis in non-neutropenic adults : Guideline-based management in the intensive care unit. Anaesthesist. 2013;62(12):1003-9
  • Knoll P, Oppermann J, Vehreschild J, Beyer F, Kaulhausen T, Siewe J, et al (2013). Rotating physician in CHIR-Net. Evaluation of the curriculum. Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen. 2013;84(12):1062-6
  • Maschmeyer G, Heinz WJ, Hertenstein B, Horst HA, Requadt C, Wagner T, et al (2013). Immediate versus deferred empirical antifungal (IDEA) therapy in high-risk patients with febrile neutropenia: a randomized, double-blind, placebo-controlled, multicenter study. Eur J Clin Microbiol Infect Dis. 2013;32(5):679-89
  • Mullane KM, Cornely OA, Crook DW, Golan Y, Louie TJ, Miller MA, Josephson MA, Gorbach SL (2013). Renal impairment and clinical outcomes of Clostridium difficile infection in two randomized trials. Am J Nephrol. 2013;38(1):1-11
  • Pagano L, Cornely OA, Busca A, Caira M, Cesaro S, Gasbarrino C, Girmenia C, Heinz WJ, Herbrecht R, Lass-Flörl C, Nosari A, Potenza L, Racil Z, Rickerts V, Sheppard DC, Simon A, Ullmann AJ, Valentini CG, Vehreschild JJ, Candoni A, Vehreschild MJ (2013). Combined antifungal approach for the treatment of invasive mucormycosis in patients with hematological diseases: a report from the SEIFEM and FUNGISCOPE registrier. Haematologica. 2013;98(10):e127-30
  • Pagano L, Cornely OA, Busca A, Caira M, Cesaro S, Gasbarrino C, et al (2013). Combination therapy of Mucormycosis in Hematology: An Analysis of SEIFEM and FUNGISCOPE Register Studies. Internist. 2013;54:73
  • Reinwald M, Spiess B, Heinz WJ, Heussel CP, Bertz H, Cornely OA, et al (2013). Aspergillus PCR-Based Investigation of Fresh Tissue and Effusion Samples in Patients with Suspected Invasive Aspergillosis Enhances Diagnostic Capabilities. J Clin Microbiol. 2013;51(12):4178-85
  • Tacke D, Koehler P, Cornely OA (2013). Fungal endocarditis. Curr Opin Infect Dis. Dec;26(6):501-7
  • Vehreschild JJ, Birtel A, Vehreschild MJ, Liss B, Farowski F, Kochanek M, Sieniawski M, Steinbach A, Wahlers K, Fätkenheuer G, Cornely OA (2013). Mucormycosis treated with posaconazole: review of 96 case reports. Crit Rev Microbiol. Aug;39(3):310-24
  • Vehreschild MJ, Vehreschild JJ, Hubel K, Hentrich M, Schmidt-Hieber M, Christopeit M, et al (2013). Diagnosis and management of gastrointestinal complications in adult cancer patients: evidence-based guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Oncol. 2013;24(5):1189-202 
  • Vehreschild JJ, Morgen G, Cornely OA, Hartmann P, Koch S, Kalka-Moll W, et al (2013). Evaluation of an infectious disease consultation programme in a German tertiary care hospital. Infection. 2013;41(6):1121-8
  • Würthwein G, Cornely OA, Trame MN, Vehreschild JJ, Vehreschild MJ, Farowski F, Müller C, Boos J, Hempel G, Hallek M, Groll AH (2013). Population pharmacokinetics of escalating doses of caspofungin in a phase II study of patients with invasive aspergillosis. Antimicrob Agents Chemother. Apr;57(4):1664-71

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Martin Denzel

  • Parker-Duffen JL, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel MS, Ranscht B, Walsh K (2013). T-Cadherin is essential for adiponectin-mediated revascularization. Journal of Biological Chemistry. 288 (34), 24886-24897
  • Cattaruzza S, Ozerdem U, Denzel MS, Ranscht B, Bulian P, Cavallaro U, Zanocco D, Colombatti A, Stallcup WB, Perris R (2013). Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells. Angiogenesis. 16 (2), 309-32

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Sabine Eming

  • Agarwal P, Schulz JN, Blumbach K, Andreasson K, Heinegård D, Paulsson M, Mauch C, Eming SA, Eckes B, Krieg T (2013). Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies. Matrix Biol. 8;32(6):325-31
  • Al Ghazal P, Herberger K, Schaller J, Strölin A, Hoff NP, Goerge T, Roth H, Rabe E, Karrer S, Renner R, Maschke J, Horn T, Hepp J, Eming SA, Wollina U, Zutt M, Sick I, Splieth B, Dill D, Klode J, Dissemond J (2013). Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients. Orphanet J Rare Dis. 8;8(1):136
  • Deppermann C, Cherpokova D, Nurden P, Schulz JN, Thielmann I, Kraft P, Vögtle T, Kleinschnitz C, Dütting S, Krohne G, Eming SA, Nurden AT, Eckes B, Stoll G, Stegner D, Nieswandt B (2013). Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice. J Clin Invest Jul. 1. pii: 69210 
  • Etich J, Bergmeier V, Frie C, Kreft S, Bengestrate L, Eming SA, Mauch C, Eckes B, Ulus H, Lund FE, Rappl G, Abken H, Paulsson M, Brachvogel B (2013). PECAM1(+)/Sca1(+)/CD38(+) vascular cells transform into myofibroblast-like cells in skin wound repair. PLoS One. 8(1):e53262
  • Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA (2013). Proteolytic processing regulates placental growth factor activities. J Biol Chem. 21;288(25):17976-89
  • Richardson R, Slanchev K, Kraus C, Knyphausen P, Eming SA, Hammerschmidt M (2013). Adult zebrafish as a model system for cutaneous wound-healing research. J Invest Dermatol. 133(6):1655-65
  • Traub S, Morgner J, Martino MM, Höning S, Swartz MA, Wickström SA, Hubbell JA, Eming SA (2013). The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 34(24):5958-68

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Lukas P. Frenzel

  • Leskov I, Pallasch CP, Drake A, Iliopoulou BP, Souza A, Shen CH, Schweighofer CD, Abruzzo L, Frenzel LP, Wendtner CM, Hemann MT, Chen J (2013). Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies. Oncogene. Feb 21;32(8):1066-72
  • Riabinska A, Daheim M, Herter-Sprie GS, Winkler J, Fritz C, Hallek M, Thomas RK, Kreuzer KA, Frenzel LP, Monfared P, Martins-Boucas J, Chen S, Reinhardt HC (2013). Therapeutic Targeting of a Robust Non-Oncogene Addiction to PRKDC in ATM-Defective Tumors. Sci Transl Med. Jun 12;5(189):189ra78. doi: 10.1126/scitranslmed.3005814

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Peter Frommolt

  • Schiffer PH, Kroiher M, Kraus C, Koutsovoulos GD, Kumar S, Camps JI, Nsah NA, Stappert D, Morris K, Heger P, Altmüller J, Frommolt P, Nürnberg P, Thomas WK, Blaxter ML, Schierenberg E (2013). The genome of Romanomermis culicivorax: revealing fundamental changes in the core developmental genetic toolkit in Nematoda. BMC Genomics. 2013 Dec 27;14:923. doi: 10.1186/1471-2164-14-923
  • Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Khan TN, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Neubauer BA, Nürnberg P, Noegel AA (2013). CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013 Dec 20;22(25):5199-214. doi: 10.1093/hmg/ddt374. Epub 2013 Aug 4
  • Jordanovski D, Herwartz C, Pawlowski A, Taute S, Frommolt P, Steger G (2013). The hypoxia-inducible transcription factor ZNF395 is controlled by IĸB kinase-signaling and activates genes involved in the innate immune response and cancer. PLoS One. 2013 Sep 23;8(9):e74911. doi: 10.1371/journal.pone.0074911. ECollection 2013
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU, Kurschat CE (2013). Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.
    BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559
  • Elfimova N, Sievers E, Eischeid H, Kwiecinski M, Noetel A, Hunt H, Becker D, Frommolt P, Quasdorff M, Steffen HM, Nürnberg P, Büttner R, Teufel A, Dienes HP, Drebber U, Odenthal M (2013). Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration.
    Biochim Biophys Acta. May;1833(5):1190-8. doi: 10.1016/j.bbamcr.2013.01.023. Epub 2013 Feb 5
  • Gharbi H, Fabretti F, Bharill P, Rinschen MM, Brinkkötter S, Frommolt P, Burst V, Schermer B, Benzing T, Müller RU (2013). Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. Aging Cell. Apr 9. doi: 10.1111/acel.12081. Epub 2013 May 15

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Martin Graef

  • Graef M, Friedman J, Graham C, Babu M, Nunnari J (2013). ER exit sites are physical and functional core autophagosome biogenesis components. Mol Biol Cell. Sep;24(18):2918-31. doi: 10.1091/mbc.E13-07-0381. Epub 2013 Jul 31 
  • Lackner LL, Ping H, Graef M, Murley A, Nunnari J (2013). Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria. Proc Natl Acad Sci USA. 110, 458-467

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Michael Hallek

  • Böttcher S, Hallek M, Ritgen M, Kneba M (2013). The role of minimal residual disease measurements in the therapy for CLL: is it ready for prime time? Hematol Oncol Clin North Am. Apr;27(2):267-88. doi: 10.1016/j.hoc.2013.01.005
  • Clinical Lung Cancer Genome Project (CLCGP); Network Genomic Medicine (NGM) (2013). A genomics-based classification of human lung tumors. Sci Transl Med. Oct 30;5(209):209ra153. doi: 10.1126/scitranslmed.3006802
  • Cramer P, Fink AM, Busch R, Eichhorst B, Wendtner CM, Pflug N, Langerbeins P, Bahlo J, Goede V, Schubert F, Döhner H, Stilgenbauer S, Dreger P, Kneba M, Böttcher S, Mayer J, Hallek M, Fischer K (2013). Second-line therapies of patients initially treated with fludarabine and cyclophosphamide or fludarabine, cyclophosphamide and rituximab for chronic lymphocytic leukemia within the CLL8 protocol of the German CLL Study Group. Leuk Lymphoma. 2013 Aug;54(8):1821-2. doi: 10.3109/10428194.2013.796050. Epub 2013 Jun 12
  • Dreger P, Schnaiter A, Zenz T, Böttcher S, Rossi M, Paschka P, Bühler A, Dietrich S, Busch R, Ritgen M, Bunjes D, Zeis M, Stadler M, Uharek L, Scheid C, Hegenbart U, Hallek M, Kneba M, Schmitz N, Döhner H, Stilgenbauer S (2013). TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial. Blood. Apr 18;121(16):3284-8. doi: 10.1182/blood-2012-11-469627. Epub 2013 Feb 22
  • Fedorchenko O, Stiefelhagen M, Peer-Zada AA, Barthel R, Mayer P, Eckei L, Breuer A, Crispatzu G, Rosen N, Landwehr T, Lilienthal N, Möllmann M, Montesinos-Rongen M, Heukamp L, Dürig J, Hallek M, Fingerle-Rowson G, Herling M (2013). CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. May 16;121(20):4126-36. doi: 10.1182/blood-2012-11-466250. Epub 2013 Apr 1
  • Hallek M (2013). Signaling the end of chronic lymphocytic leukemia: new frontline treatment strategies. Blood. 2013 Nov 28;122(23):3723-34. doi: 10.1182/blood-2013-05-498287. Epub 2013 Sep 24
  • Hallek M (2013). Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment. Am J Hematol. 2013 Sep;88(9):803-16. doi :10.1002/ajh.23491. Review
  • Hallek M (2013). Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment. Am J Hematol. May 30. doi: 10.1002/ajh.23491 
  • Hallek M, Knauf W, Dreyling M, Trümper L (2013). Current and future indications for bendamustine: chronic lymphocytic leukemia, indolent lymphoma, mantle cell lymphoma and diffuse large B-cell lymphomas. Onkologie. 36 Suppl 1:11-8. doi: 10.1159/000346106. Epub 2013 Jan 28
  • Held G, Zeynalova S, Murawski N, Ziepert M, Kempf B, Viardot A, Dreyling M, Hallek M, Witzens-Harig M, Fleckenstein J, Rübe C, Zwick C, Glass B, Schmitz N, Pfreundschuh M (2013). Impact of rituximab and radiotherapy on outcome of patients with aggressive B-cell lymphoma and skeletal involvement. J Clin Oncol. 2013 Nov 10;31(32):4115-22. doi: 10.1200/JCO.2012.48.0467. Epub 2013 Sep 23
  • Hopfinger G, Busch R, Pflug N, Weit N, Westermann A, Fink AM, Cramer P, Reinart N, Winkler D, Fingerle-Rowson G, Stilgenbauer S, Döhner H, Kandler G, Eichhorst B, Hallek M, Herling M (2013). Sequential chemoimmunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia. Cancer. Jun 15;119(12):2258-67. doi: 10.1002/cncr.27972. Epub 2013 Mar 19
  • Ihrig K, Fath B, Fuchs M, Hallek M, Marschner N, Naumann R, Röllig C, Saussele S, Tesch H, Gökbuget N (2013). Focus on academic multicenter trials: impact of the German drug law on hematological/oncological therapy optimization trials. Onkologie. 36 Suppl 2:23-8. doi: 10.1159/000348254
  • Münch RC, Janicki H, Völker I, Rasbach A, Hallek M, Büning H, Buchholz CJ (2013). Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene Transfer. Mol Ther. Jan;21(1):109-18. doi: 10.1038/mt.2012.186. Epub 2012 Sep 11
  • Reinart N, Nguyen PH, Boucas J, Rosen N, Kvasnicka HM, Heukamp L, Rudolph C, Ristovska V, Velmans T, Mueller C, Reiners KS, von Strandmann EP, Krause G, Montesinos-Rongen M, Schlegelberger B, Herling M, Hallek M, Fingerle-Rowson G (2013). Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor. Blood. Jan 31;121(5):812-21. doi: 10.1182/blood-2012-05-431452. Epub 2012 Nov 1
  • Reiners KS, Topolar D, Henke A, Simhadri VR, Kessler J, Sauer M, Bessler M, Hansen HP, Tawadros S, Herling M, Krönke M, Hallek M, Pogge von Strandmann E (2013). Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity. Blood. May 2;121(18):3658-65. doi: 10.1182/blood-2013-01-476606. Epub 2013 Mar 18
  • Riabinska A, Daheim M, Herter-Sprie GS, Winkler J, Fritz C, Hallek M, Thomas RK, Kreuzer KA, Frenzel LP, Monfared P, Martins-Boucas J, Chen S, Reinhardt HC (2013). Therapeutic Targeting of a Robust Non-Oncogene Addiction to PRKDC in ATM-Defective Tumors. Sci Transl Med. Jun 12;5(189):189ra78. doi: 10.1126/scitranslmed.3005814
  • Rothe A, Jachimowicz RD, Borchmann S, Madlener M, Keßler J, Reiners KS, Sauer M, Hansen HP, Ullrich RT, Chatterjee S, Borchmann P, Yazaki P, Koslowsky TC, Engert A, Heukamp LC, Hallek M, von Strandmann EP (2013). The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma. Int J Cancer. 2013 Nov 14. doi: 10.1002/ijc.28609. Epub 2013 Nov 29
  • Schnaiter A, Paschka P, Rossi M, Zenz T, Bühler A, Winkler D, Cazzola M, Döhner K, Edelmann J, Mertens D, Kless S, Mack S, Busch R, Hallek M, Döhner H, Stilgenbauer S (2013). NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG. Blood. Aug 15;122(7):1266-70. doi: 10.1182/blood-2013-03-488197. Epub 2013 Jul 2
  • Theurich S, Fischmann H, Chakupurakal G, Shimabukuro-Vornhagen A, Chemnitz JM, Holtick U, Rothe A, Scheid C, Hallek M, Skoetz N, von Bergwelt-Baildon M (2013). Anti-thymocyte globulins for post-transplant graft-versus-host disease prophylaxis-A systematic review and meta-analysis. Crit Rev Oncol Hematol. 2013 Oct;88(1):178-86. doi: 10.1016/j.critrevonc.2013.03.009. Epub 2013 Apr 2
  • Theurich S, Malcher J, Wennhold K, Shimabukuro-Vornhagen A, Chemnitz J, Holtick U, Krause A, Kobe C, Kahraman D, Engert A, Scheid C, Chakupurakal G, Hallek M, von Bergwelt-Baildon M (2013). Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission. J Clin Oncol. Feb 10;31(5):e59-63. doi: 10.1200/JCO.2012.43.6832. Epub 2012 Dec 26
  • Theurich S, Wennhold K, Wedemeyer I, Rothe A, Hübel K, Shimabukuro-Vornhagen A, Holtick U, Hallek M, Scheid C, von Bergwelt-Baildon M (2013). CD30-targeted therapy with brentuximab vedotin and DLI in a patient with T-cell posttransplantation lymphoma: induction of clinical remission and cellular immunity. Transplantation. Aug 15;96(3):e16-8. doi: 10.1097/TP.0b013e31829a9258
  • Theurich S, Fischmann H, Chakupurakal G, Shimabukuro-Vornhagen A, Chemnitz JM, Holtick U, Rothe A, Scheid C, Hallek M, Skoetz N, von Bergwelt-Baildon M (2013). Anti-thymocyte globulins for post-transplant graft-versus-host disease prophylaxis-A systematic review and meta-analysis. Crit Rev Oncol Hematol. 2013 Oct; doi:pii: S1040-8428(13)00069-3. 10.1016/j.critrevonc.2013.03.009. Epub 2013 Apr 2
  • Thiem S, Pierce TP, Palmieri M, Putoczki TL, Buchert M, Preaudet A, Farid RO, Love C, Catimel B, Lei Z, Rozen S, Gopalakrishnan V, Schaper F, Hallek M, Boussioutas A, Tan P, Jarnicki A, Ernst M (2013). mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mich. J Clin Invest. Feb 1;123(2):767-81. doi: 10.1172/JCI65086. Epub 2013 Jan 16
  • Tresckow B von, Boell B, Eichenauer DA, Beschorner D, Knop S, Goebeler ME, Marcus Chemnitz J, Hallek M, Engert A, Huebel K (2013). Anti-EGFR antibody cetuximab in refractory or relapsed multiple myeloma: A phase II prospective clinical trial. Leuk Lymphoma. May 29. Epub 2013 Jul 29
  • Würthwein G, Cornely OA, Trame MN, Vehreschild JJ, Vehreschild MJ, Farowski F, Müller C, Boos J, Hempel G, Hallek M, Groll AH (2013). Population pharmacokinetics of escalating doses of caspofungin in a phase II study of patients with invasive aspergillosis. Antimicrob Agents Chemother. Apr;57(4):1664-71. doi: 10.1128/AAC.01912-12. Epub 2013 Jan 18

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Matthias Hammerschmidt

  • Dijk van FS, Zillikens MC, Micha D, Riessland M, Marcelis CL, de Die-Smulders CE, Milbradt J, Franken AA, Harsevoort AJ, Lichtenbelt KD, Pruijs HE, Rubio-Gozalbo ME, Zwertbroek R, Moutaouakil Y, Egthuijsen J, Hammerschmidt M, Bijman R, Semeins CM, Bakker AD, Everts V, Klein-Nulend J, Campos-Obando N, Hofman A, te Meerman GJ, Verkerk AJ, Uitterlinden AG, Maugeri A, Sistermans EA, Waisfisz Q, Meijers-Heijboer H, Wirth B, Simon ME, Pals G (2013). PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med. 369, 1529-1536
  • Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slnchev K, Hammerschmidt M, Topczeweski J, Whitfield T (2013). Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene. Development. 140, 4362-4374
  • Liu F, Pogoda HM, Pearson CA, Ohyama K, Löhr H, Hammerschmidt M, Placzek M (2013).  Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis. Development. 140, 1111-1122
  • Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA (2013). Long-chain Acyl-CoA synthetase regulates Smad activity and dorsoventral patterning in the zebrafish embryo. Dev Cell. 27, 635-647
  • Richardson R, Slanchev K, Kraus C, Knyphausen P, Eming S, Hammerschmidt M (2013). Adult zebrafish as a model for cutaneous wound-healing research. J Invest Dermatol. 133, 1655-1665

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Hans Christian Hennies

  • Eckl KM, Tidhar R, Thiele H, Oji V, Hausser I, Brodesser S, Preil ML, Önal-Akan A, Stock F, Becker K, Casper R, Nürnberg G, Altmüller J, Nürnberg P, Traupe H, Futerman AH, Hennies HC (2013). Impaired ceramide synthesis causes autosomal recessive congenital ichthyosis and reveals the importance of ceramide acyl chain length for epidermal terminal differentiation. J Invest Dermatol. 133:2202-2211 
  • Hennies HC (2013). Rare diseases: New generations of molecular genetic diagnostics. Klinik 22(5):41-44
  • Nellen RGL, Steijlen PM, Hennies HC, Fischer J, Munro CS, Jonkman MF, van Steensel MAM, van Gele M (2013). Haplotype analysis in Western European patients with Mal de Meleda: founder effect for the W15R mutation in the SLURP1 Gene. Br J Dermatol. 168:1372-1374 (2013)
  • Pasternack SM, Refke M, Paknia E, Hennies HC, Franz T, Schäfer N, Fryer A, van Steensel M, Sweeney E, Just M, Grimm C, Kruse R, Ferrándiz C, Nöthen MM, Fischer U, Betz RC (2013). Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex. Am J Hum Genet. Jan 10;92(1):81-7
  • Shao K, Koch C, Gupta MK, Lin Q, Lenz M, Laufs S, Denecke B, Schmidt M, Linke M, Hennies HC, Hescheler J, Zenke M, Zechner U, Šarić T, Wagner W (2013). Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. Mol Ther. Jan;21(1):240-50

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Marco Herling

  • Fedorchenko O, Stiefelhagen M, Peer Zada AA, Barthel R, Mayer P, Eckei L, Breuer A, Crispatzu G, Rosen N, Landwehr T, Lilienthal N, Möllmann M, Montesinos-Rongen M, Heukamp L, Dürig J, Hallek M, Fingerle-Rowson G, Herling M (2013). CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. 2013 May 16;121(20):4126-36
  • Heinrich T, Rengstl B, Muik A, Petkova M, Schmid F, Wistinghausen R, Warner K, Crispatzu G, Hansmann ML, Herling M, von Laer D, Newrzela S (2013). Mature T-cell lymphomagenesis induced by retroviral insertional activation of Janus kinase 1. Mol Ther. 2013 Jun;21(6):1160-8
  • Hopfinger G, Herling M (2013). Diagnostik und Therapie von Peripheren T-Zell Lymphomen. In: Hopfinger G. ed., Aktuelle Therapieoptionen bei aggressiven Lymphomen. (chapter 4, pp 45-62, in German), 1st edition 2013, UNI-MED Science (ISBN: 978-3-8374-1407-3)
  • Hopfinger G, Busch R, Pflug N, Weit N, Westermann A, Fink AM, Cramer P, Reinart N, Winkler D, Fingerle-Rowson G, Stilgenbauer S, Döhner H, Kandler G, Eichhorst B, Hallek M, Herling M (2013). Sequential chemo-immunotherapy of fludarabine, mitoxantrone, and cyclophosphamide induction followed by alemtuzumab consolidation is effective in T-cell prolymphocytic leukemia. Cancer. 2013 Jun 15;119(12):2258-67
  • Myhrinder AL, Hellqvist E, Bergh AC, Jansson M, Nilsson K, Hultman P, Jonasson J, Buhl AM, Pedersen LB, Jurlander J, Klein E, Weit N, Herling M, Rosenquist R, Rosén A (2013). Molecular characterization of neoplastic and normal 'sister' lymphoblastoid B-cell lines from chronic lymphocytic leukemia. Leuk Lymphoma. 2013 Aug;54(8):1769-79
  • Reinart N, Nguyen PH, Boucas J, Rosen N, Kvasnicka HM, Heukamp L, Rudolph C, Ristovska V, Velmans T, Mueller C, Reiners KS, Pogge von Strandmann E, Krause G, Montesinos-Rongen M, Schlegelberger B, Herling M, Hallek M, Fingerle-Rowson G (2013). Delayed development of chronic lymphocytic leukemia in the absence of macrophage migration inhibitory factor. Blood. 2013 Jan 31;121(5):812-21
  • Reiners KS, Topolar D, Henke A, Simhadri VR, Kessler J, Sauer M, Bessler M, Hansen HP, Tawadros S, Herling M, Krönke M, Hallek M, Pogge von Strandmann E (2013). Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity. Blood. 2013 May 2;121(18):3658-65
  • Warner K, Crispatzu G, Al-Ghaili N, Weit N, Florou V, You MJ, Newrzela S, Herling M (2013). Models for mature T-cell lymphomas - A critical appraisal of experimental systems and their contribution to current T-cell tumorigenic concepts. Crit Rev Oncol Hematol. 2013 Dec;88(3):680-95
  • Warner K, Weit N, Crispatzu G, Admirand J, Jones D, Herling M (2013). T-cell receptor signaling in peripheral T-cell lymphoma - A review of patterns of alterations in a central growth regulatory pathway. Curr Hematol Malig Rep. 2013 Sep;8(3):163-72

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Thorsten Hoppe

  • Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann P, Schüll S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Krönke M, Mauch C, Hoppe T, Kashkar H (2013). Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA. Cell Rep. 3, 881-91
  • Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B (2013). DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature. 501, 416-20
  • Gazda L, Pokrzywa W, Hellerschmied D, Löwe T, Forné I, Mueller-Planitz F, Hoppe T, Clausen T (2013). The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans. Cell. 152, 183-95
  • Pokrzywa W, Hoppe T (2013). Chaperoning myosin assembly in muscle formation and aging. Worm. 2, e25644
  • Schipanski A, Lange S, Segref A, Gutschmidt A, Lomas DA, Miranda E, Schweizer M, Hoppe T, Glatzel M (2013). A novel interaction between aging and ER overload in a protein conformational dementia. Genetics. 193, 865-76
  • Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M (2013). Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide. Nat Chem Biol. 9, 693-700

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Hamid Kashkar

  • Böcke A, Carstens AC, Neacsu CD, Baschuck N, Haubert D, Kashkar H, Utermöhlen O, Pongratz C, Krönke M (2013). TNF-Receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion. Br J Cancer. 2013, 109:422-32
  • Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann PN, Schüll S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Krönke M, Mauch C, Hoppe T, Kashkar H (2013). Ubiquitin C-Terminal Hydrolase-L1 Potentiates Cancer Chemosensitivity by Stabilizing NOXA. Cell Rep. 3(3):881-91
  • Förster A, Falcone FH, Gibbs BF, Preussner LM, Fiebig BS, Altunok H, Seeger JM, Cerny-Reiterer S, Rabenhors A, Papenfuss K, Valent P, Kashkar H, Hartmann K (2013). Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils. Leuk Lymphoma. 54:835-42
  • Förster A, Preussner LM, Seeger JM, Rabenhorst A, Kashkar H, Mrowietz U, Hartmann K (2013). Dimethylfumarate induces apoptosis in human mast cells. Exp Dermatol. 2013, 22:719-724
  • Gruber S, Straub B, Ackermann JP, Wunderlich CM, Mauer J, Seeger JM, Büning H, Heukamp L, Kashkar H, Schirmacher P, Brüning JC, Wunderlich FT (2013). Obesity Promotes Liver Carcinogenesis via Mcl-1 Stabilization Independent of IL-6Rα Signaling. Cell Rep. 4(4):669-680   

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Peter Kloppenburg

  • Fusca D, Husch A, Baumann A, Kloppenburg P (2013). Choline acetyltransferase-like immunoreactivity in a physiologically distinct subtype of olfactory nonspiking local interneurons in the cockroach (periplaneta americana). J Comp Neurol. 2013 Oct 15;521(15):3556-69. doi: 10.1002/cne.23371
  • Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, Brönneke HS, Dietrich MO, Jordan SD, Saletore Y, Elemento O, Belgardt BF, Franz T, Horvath TL, Rüther U, Jaffrey SR, Kloppenburg P, Brüning JC (2013). The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat Neurosci. 2013 Aug;16(8):1042-8. doi: 10.1038/nn.3449
  • Joucla S, Franconville R, Pippow A, Kloppenburg P, Pouzat C 2013). Estimating background-subtracted fluorescence transients in calcium imaging experiments: a quantitative approach. Cell Calcium. 2013 Aug;54(2):71-85. doi: 10.1016/j.ceca.2013.04.005
  • Newton AJ, Hess S, Paeger L, Vogt MC, Fleming Lascano J, Nillni EA, Brüning JC, Kloppenburg P, Xu AW (2013). AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice. Endocrinology. 2013 Jan;154(1):172-83. doi: 10.1210/en.2012-1643
  • Tovar S, Paeger L, Hess S, Morgan DA, Hausen AC, Brönneke HS, Hampel B, Ackermann PJ, Evers N, Büning H, Wunderlich FT, Rahmouni K, Kloppenburg P, Brüning JC (2013). K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metab. 2013 Sep 3;18(3):445-55. doi: 10.1016/j.cmet.2013.08.006
  • Ziemann A, Hess S, Bhuwania R, Linder S, Kloppenburg P, Noegel AA, Clemen CS (2013). CRN2 enhances the invasiveness of glioblastoma cells. Neuro Oncol. 2013 May;15(5):548-61. doi: 10.1093/neuonc/nos388

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Natalia Kononenko

  • Kononenko NL, Diril MK, Puchkov D, Kintscher M, Koo SJ, Pfuhl G, Winter Y, Wienisch M, Klingauf J, Breustedt J, Schmitz D, Maritzen T, Haucke V (2013). Compromised fidelity of endocytic synaptic vesicle protein sorting in the absence of stonin 2. PNAS. 110, E526-535
  • Sakaba T, Kononenko NL, Bacetic J, Perchstein A, Schmoranzer J, Yao L, Barth H, Schupljakov O, Kobler O, Aktories K, Haucke V (2013). Fast neurotransmitter release regulated by the endocytic scaffold intersectin. PNAS. 110, 8266-8271

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Jan-Wilhelm Kornfeld

  • Kornfeld JW, Baitzel C, Könner AC, Nicholls HT, Vogt MC, Herrmanns K, Scheja L, Haumaitre C, Wolf AM, Knippschild U, Seibler J, Cereghini S, Heeren J, Stoffel M, Brüning JC (2013). Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature. 2013, Feb 7;494(7435):111-5

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Thomas Krieg

  • Agarwal P, Schulz JN, Blumbach K, Andreasson K, Heinegård D, Paulsson M, Mauch C, Eming SA, Eckes B, Krieg T (2013). Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies. Matrix Biol. Mar 15. doi:pii: S0945-053X(13)00030-9.10.1016/j.matbio.2013.02.010. Epub 2013 Mar 15
  • Buonincontri G, Methner C, Carpenter TA, Hawkes RC, Sawiak SJ, Krieg T (2013). MRI and PET in mouse models of myocardial infarction. J Vis Exp. Dec 19;(82):e50806. doi:10.3791/50806
  • Buonincontri G, Methner C, Krieg T, Carpenter TA, Sawiak SJ (2013). A fast protocolfor infarct quantification in mice. J Magn Reson Imaging. Aug;38(2):468-73. doi: 10.1002/jmri.24001. Epub 2013 Jan 4
  • Buonincontri G, Sawiak SJ, Methner C, Krieg T, Hawkes RC, Carpenter TA (2013). PET/MRI in the infarcted mouse heart with the Cambridge split magnet. Nucl Instrum Methods Phys Res A. Feb 21;702
  • Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, Krieg T, Brookes PS, Murphy MP (2013). Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med. Jun;19(6):753-9. doi: 10.1038/nm.3212. Epub 2013 May 26
  • Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D, Matucci-Cerinic M, DUO Registry Group (2013). Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry. Clin Exp Rheumatol. Mar-Apr;31(2 Suppl 76):71-80. Epub 2013 Jul 22
  • Methner C, Lukowski R, Grube K, Loga F, Smith RA, Murphy MP, Hofmann F, Krieg T (2013). Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G. Basic Res Cardiol. 108(2):337. doi: 10.1007/s00395-013-0337-1. Epub 2013 Feb 20
  • Methner C, Buonincontri G, Hu CH, Vujic A, Kretschmer A, Sawiak S, Carpente A, Stasch JP, Krieg T (2013). Riociguat reduces infarct size and post-infarct heart failure in mouse hearts: insights from MRI/PET imaging. PLoS One. Dec 31;8(12):e83910. doi: 10.1371/journal.pone.0083910. eCollection 2013
  • Moinzadeh P, Agarwal P, Bloch W, Orteu C, Hunzelmann N, Eckes B, Krieg T (2013). Systemic sclerosis with multiple nodules: characterization of the extracellular Matrix. Arch Dermatol Res. 2013, 305, 645-652
  • Radovanac K, Morgner J, Schulz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA (2013). Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. EMBO J. May 15;32(10):1409-24. doi: 10.1038/emboj.2013.90. Epub 2013 Apr 23
  • Reich-Schupke S, Aim J, Altmeyer P, Bachter D, Bayerl C, Beissert S, Bieber T, Bohmer J, Dill D, Dippel E, Ducker P, Effendy I, El Gammal S, Eisner P, Enk A, Feldmann-Boddeker I, Frank H, Gehring W, Gieler U, Goebeler M, GorgeT, Gollnick H, Grabbe S, Gross G, Gudat W, Happ A, Herbst R, Hermes B, Hoff NP, John SM, Jungelhulsing M, Junger M, Kaatz M, KappA, Kaufmann R, Klode J, Knaber K, Konig A, Krieg T, Kohl P, Kowalzick L, Lehmann P, Loftier H, Maschke J, Marsch W, Mechtel D, Mohr P, Moll I, Muller M, Nashan D, Ockenfels HM, Peter RU, Pillekamp H, Rempel R, Ruzicka T, Salfeld K, Sander C, Schaller J, Scharffetter-Kochanek K, Schuler G, Schulze HJ, Schwarz T, Splieth B, Stege H, Stolz W, Strolin A, Tran H, Tronnier M, Ulrich J, Vogt T, Wagner G, Welzel J, Willgeroth T, Wollina U, Zillikens D, Zouboulis CC, Zuberbier T, Zutt M, Stucker M (2013). Phlebology in German departments of dermatology. An analysis on behalf of the German Society of Phlebology. Hautarzt. 2013, 64, 685-694
  • Schuster J, Moinzadeh P, Kurschat C, Benzing T, Krieg T, Weber M, Hunzelmann N (2013). Proteinuria in systemic sclerosis: reversal by ACE inhibition. Rheumatol Int. 33, 2225-2230

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Martin Krönke

  • Augner D, Krut O, Slavov N, Gerbino DC, Sahl HG, Benting J, Nising CF, Hillebrand S, Krönke M, Schmalz HG (2013). On the antibiotic and antifungal activity of pestalone, pestalachloride A, and structurally related compounds. J Nat Prod. 76: 1519-22
  • Boecke A, Carstens AC, Neacsu CD, Baschuk N, Haubert D, Kashkar H, Utermöhlen O, Pongratz C, Krönke M (2013). TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion. Br J Cancer. 109: 422-32
  • Brinkmann K, Zigrino P, Witt A, Schell M, Ackermann L, Broxtermann P, Schüll S, Andree M, Coutelle O, Yazdanpanah B, Seeger JM, Klubertz D, Drebber U, Hacker UT, Krönke M, Mauch C, Hoppe T, Kashkar H (2013). Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA. Cell Rep. 3: 881-91
  • Reiners KS, Topolar D, Henke A, Simhadri VR, Kessler J, Sauer M, Bessler M, Hansen HP, Tawadros S, Herling M, Krönke M, Hallek M, Pogge von Strandmann E (2013). Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity. Blood. 121: 3658-65

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Marcus Krüger

  • Berghoff BA, Konzer A, Mank NN, Looso M, Rische T, Förstner KU, Krüger M, Klug G (2013). Integrative "omics"-approach discovers dynamic and regulatory features of bacterial stress responses. PLoS Genet. Jun;9(6)
  • Boerries M, Grahammer F, Eiselein F, Buck M, Meyer C, Goedel M, Bechtel W, Zschiedrich S, Pfeifer D, Laloë D, Arrondel C, Gonçalves S, Krüger M, Harvey SJ, Busch H, Dengjel J, Huber T (2013). Molecular fingerprint of the podocyte reveals novel gene and protein regulatory networks. Kidney Int. Jun; 83(6):1052-64
  • Candasamy AJ, Haworth RS, Cuello F, Ibrahim M, Aravamudhan S, Krüger M, Holt MR, Terracciano CM, Mayr M, Gautel M, Avkiran M (2013). Phosphoregulation of the titin-cap protein telethonin in cardiac myocytes. J Biol Chem. Nov 26
  • Heinrich EM, Wagner J, Krüger M, John D, Uchida S, Weigand JE, Suess B, Dimmeler S (2013). Regulation of miR-17-92a cluster processing by the microRNA binding protein SND1. FEBS Lett. Aug 2; 587(15):2405-11
  • Jedrusik-Bode M, Studencka M, Smolka C, Baumann T, Schmidt H, Kampf J, Paap F, Martin S, Tazi J, Müller KM, Krüger M, Braun T, Bober E (2013). The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals. J Cell Sci. Nov 15;126(Pt 22):5166-77
  • Konzer A, Ruhs A, Braun H, Jungblut B, Braun T, Krüger M (2013). Stable isotope labelling in zebrafish allows in vivo monitoring of cardiac morphogenesis. Mol Cell Proteomics. 2013 Jun;12(6):1502-12
  • Konzer A, Ruhs A, Braun T, Krüger M (2013). Global protein quantification of mouse heart tissue based on the SILAC mouse. Methods Mol Biol. 1005:39-52
  • Looso M, Preussner J, Sousounis K, Bruckskotten M, Michel CS, Lignelli E, Reinhardt R, Höffner S, Krüger M, Tsonis PA, Borchardt T, Braun T (2013). A de novo assembly of the newt transcriptome combined with proteomic validation identifies new protein families expressed during tissue regeneration. Genome Biol. Feb 20;14(2):R16
  • Mukhametshina RT, Ruhs A, Singh I, Hasan D, Contreras A, Mehta A, Nikam VS, Ahlbrecht K, Carraro G, Cabrera-Fuentes HA, Jiang D, Voswinckel R, Seeger W, Bellusci S, Scharffetter-Kochanek K, Bagaeva TV, Preissner KT, Boettger T, Braun T, Krüger M, Barreto G (2013). Quantitative Proteome Analysis of Alveolar Type-II Cells Reveals a Connection of Integrin Receptor Subunits Beta 2/6 and WNT Signaling. J Proteome Res. 12(12):5598-608
  • Pohjoismäki JL, Krüger M, Al-Furoukh N, Lagerstedt A, Karhunen PJ, Braun T (2013). Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes. Mol Biosyst. Jun;9(6)
  • Rinschen M, Wu X, König T, Pisitkun T, Hagmann H, Pahmeyer C, Lamkemeyer T, Kohli P, Schnell N, Schermer B, Dryer S, Brooks B, Beltrao P, Krüger M, Brinkkötter P, Benzing T (2013). Phosphoproteomic analysis reveals regulatory mechanisms at the kidney filtration barrier. J Am Soc Nephrol. Jul; 25(7):1509-22
  • Ruhs A, Cemic F, Braun T, Krüger M (2013). ResA³: a Web Tool for Resampling Analysis of Arbitrary Annotations. PLoS One. 2013;8(1)
  • Serrano L, Martinez-Redondo P, Marazuela-Duque A, Vazquez BN, Dooley SJ, Voigt P, Beck DB, Kane-Goldsmith, Tong Q, Rabanal RM, Fondevila D, Muñoz P, Krüger M, Tischfield JA, Vaquero A (2013). The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation. Genes Dev. 2013 Mar 15; 27(6):639-53
  • Singh SK, Sethi S, Aravamudhan S, Krüger M, Grabher C (2013). Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils. PLoS One. Sep 3;8(9):e73998
  • Takefuji M, Krüger M, Sivaraj KK, Kaibuchi K, Offermanns S, Wettschureck N (2013). RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades. J Exp Med. Apr 8; 210(4):665-73

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Christian Kubisch

  • Graul-Neumann LM, Deichsel A, Wille U, Kakar N, Koll R, Bassir C, Ahmad J, Cormier-Daire V, Mundlos S, Kubisch C, Borck G, Klopocki E, Mueller TD, Doelken SC, Seemann P (2013). Homozygous missense and nonsense mutations in BMPR1B cause acromesomelic chondrodysplasia-type Grebe. Eur J Hum Genet. 2013 Oct 16. doi: 10.1038/ejhg.2013.222
  • Kakar N, Ahmad J, Kubisch C, Borck G (2013). Exon skipping and severe childhood-onset obesity caused by a leptin receptor mutation. Am J Med Genet A. 2013 Oct;161(10):2672-4. doi: 10.1002/ajmg.a.36125. Epub 2013 Aug 15
  • Basel-Vanagaite L, Hershkovitz T, Heyman E, Raspall-Chaure M, Kakar N, Smirin-Yosef P, Vila-Pueyo M, Kornreich L, Thiele H, Bode H, Lagovsky I, Dahary D, Haviv A, Hubshman MW, Pasmanik-Chor M, Nürnberg P, Gothelf D, Kubisch C, Shohat M, Macaya A, Borck G (2013). Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum. Am J Hum Genet. 2013 Sep 5;93(3):524-9. doi: 10.1016/j.ajhg.2013.07.005. Epub 2013 Aug 8
  • Sauter D, Hotter D, Engelhart S, Giehler F, Kieser A, Kubisch C, Kirchhoff F (2013). A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release. Retrovirology. 2013 Aug 10;10:85. doi: 10.1186/1742-4690-10-85
  • Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, Färkkilä M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PA, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FM, Hartikainen AL, Pouta A, van den Ende J,Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkilä K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor BJ, Trabzuni D, Rossin E, Lage K, Jacobs SB, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ, Nyholt DR, Chasman DI, Palotie A; North American Brain Expression Consortium; UK Brain Expression Consortium; International Headache Genetics Consortium (2013). Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug;45(8):912-7. doi:10.1038/ng.2676. Epub 2013 Jun 23
  • Saha B, Lessel D, Nampoothiri S, Rao AS, Hisama FM, Peter D, Bennett C, Nürnberg G, Nürnberg P, Martin GM, Kubisch C, Oshima J (2013). Ethnic-Specific WRN Mutations in South Asian Werner Syndrome Patients: Potential Founder Effect in Patients with Indian or Pakistani Ancestry. Mol Genet Genomic Med. 2013 May 1;1(1):7-14
  • International Multiple Sclerosis Genetics Consortium (2013). MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis. Brain. Jun;136(Pt 6):1778-82. doi: 10.1093/brain/awt101
  • Wildhardt G, Zirn B, Graul-Neumann LM, Wechtenbruch J, Suckfüll M, Buske A, Bohring A, Kubisch C, Vogt S, Strobl-Wildemann G, Greally M, Bartsch O, Steinberger D (2013). Spectrum of novel mutations found in Waardenburg syndrome types 1 and 2: implications for molecular genetic diagnostics. BMJ Open. Mar 18;3(3). doi:pii: e001917. 10.1136/bmjopen-2012-001917. Print 2013
  • Lill CM, Schjeide BM, Graetz C, Liu T, Damotte V, Akkad DA, Blaschke P, Gerdes LA, Kroner A, Luessi F, Cournu-Rebeix I, Hoffjan S, Winkelmann A, Touze E, Pico F, Corcia P, Otaegui D, Antigüedad A, Alcina A, Comabella M, Montalban X, Olascoaga J, Matesanz F, Dörner T, Li SC, Steinhagen-Thiessen E, Lindenberger U, Chan A, Rieckmann P, Hartung HP, Aktas O, Lohse P, Buttmann M, Kümpfel T, Kubisch C, Zettl UK, Epplen JT, Fontaine B, Zipp F, Vandenbroeck K, Bertram L (2013). Genome-wide significant association of ANKRD55 rs6859219 and multiple sclerosis risk. J Med Genet. Mar;50(3):140-3. doi: 10.1136/jmedgenet-2012-101411. Epub 2013 Jan 12
  • Volk AE, Lang-Roth R, Yigit G, Borck G, Nuernberg G, Rosenkranz S, Nuernberg P, Kubisch C, Beutner D (2013). A Novel MYO6 Splice Site Mutation Causes Autosomal Dominant Sensorineural Hearing Loss Type DFNA22 with a Favourable Outcome after Cochlear Implantation. Audiol Neurootol. ;18(3):192-9. doi: 10.1159/000350246. Epub 2013 Apr 26

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Leo Kurian

  • Cai W, Albini S, Wei K, Willems E, Guzzo RM, Tsuda M, Giordani L, Spiering S, Kurian L, Yeo GW, Puri PL, Mercola M (2013). Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment. Genes & development. 11; 27(21):2332-44
  • Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Izpisua Belmonte JC (2013). Conversion of human fibroblasts to angioblast-like progenitor cells. Nature Methods. Jan;10(1):77-83. Published with a News & Views entitled ‘An indirect approach to generating specific human cell types’ by Prof. M. Wernig (Nature Methods (10):44-45)

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Thomas Langer

  • Anand R, Langer T, Baker MJ (2013). Proteolytic control of mitochondrial function and morphogenesis. Biochim Biophys Acta. 1833, 195-204. doi: 10.1016/j.bbamcr.2012.06.025
  • Anton F, Dittmar G, Langer T, Escobar-Henriques M (2013). Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways. Mol Cell. 49, 487-498. doi: 10.1016/j.molcel.2012.12.003
  • Müller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn PH, Lichtenthaler SF, Motori E, Hrelia S, Wurst W, Trümbach D, Langer T, Krappmann D, Dittmar G, Tatzelt J, Winklhofer KF (2013). The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell. 49, 908-921. doi: 10.1016/j.molcel.2013.01.036
  • Potting C, Langer T (2013). Rushhour – Phospholipidtransport an mitochondrialen Membranen. Biospektrum. doi: 10.1007/s12268-013
  • Potting C, Tatsuta T, König T, Haag M, Wai T, Aaltonen MJ, Langer T (2013). TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid. Cell Metab. 18, 287-295. doi: 10.1016/j.cmet. 2013.07.008
  • Scharwey M, Tatsuta T, Langer T (2013). Mitochondrial lipid transport at a glance. J Cell Sci. 126, 5317-5323. doi: 10142/jcs.134130
  • Supale S, Thorel F, Merkwirth C, Gjinovci A, Herrera PL, Scorrano L, Meda P, Langer T, Maechler P (2013). Loss of prohibitin induces mitochondrial dam­ages altering ß-cell function and survival and is responsible for gradual diabetes develop­ment. Diabetes. 62, 3488-3499. doi: 10.2337/db13-0152
  • Tatsuta T, Scharwey M, Langer T (2013). Mitochondrial lipid trafficking. Trends Cell Biol. 24, 44-52. doi: 10.1016/j.tcb.2013.07.011
  • Wilmes C, Langer T (2013). Chapter 383. ATP23 Peptidase. Handbook of Proteolytic Enzymes (Third Ed) (pp. 1688-1690). Elsevier Ltd. doi:10.1016/B978-0-12-382219-2.00383-5

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Nils-Göran Larsson

  • Bratic A, Larsson NG (2013). The role of mitochondria in aging. J Clin Invest. Mar 1;123(3):951-7. doi: 10.1172/JCI64125. Epub 2013 Mar 1. Review
  • Harmel J, Ruzzenente B, Terzioglu M, Spåhr H, Falkenberg M, Larsson NG (2013). The Leucine-rich Pentatricopeptide Repeat-containing Protein (LRPPRC) Does Not Activate Transcription in Mammalian Mitochondria. J Biol Chem. May 31;288(22):15510-9. doi: 10.1074/jbc.M113.471649. Epub 2013 Apr 18
  • Kukat C, Larsson NG (2013). mtDNA makes a U-turn for the mitochondrial nucleoid. Trends Cell Biol. May 27. doi:pii: S0962-8924(13)00065-2. 10.1016/j.tcb.2013.04.009. Epub 2013 May 27
  • Lagouge M, Larsson, NG (2013). The role for mitochondrial DNA mutations and free radicals in disease and aging J. Intern. Med. 2013:273:529-543
  • Milenkovic D, Matic S, Kühl I, Ruzzenente B, Freyer C, Jemt E, Park CB, Falkenberg M, Larsson NG (2013). TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication. Hum Mol Genet. May 15;22(10):1983-93. doi: 10.1093/hmg/ddt051. Epub 2013 Feb 7
  • Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG (2013). Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature. 2013 Sep 19;501(7467):412-5. doi: 10.1038/nature12474. Epub 2013 Aug 21
  • Terzioglu M, Ruzzenente B, Harmel J, Mourier A, Jemt E, López MD, Kukat C, Stewart JB, Wibom R, Meharg C, Habermann B, Falkenberg M, Gustafsson CM, Park CB, Larsson NG (2013). MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation. Cell Metab. Apr 2;17(4):618-26. doi: 10.1016/j.cmet.2013.03.006  
  • Wredenberg A, Lagouge M, Bratic A, Metodiev MD, Spåhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, Habermann B, Partridge L, Park CB, Larsson NG (2013). MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet. ;9(1):e1003178. doi: 10.1371/journal.pgen.1003178. Epub 2013 Jan 3

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Ivan Matic 

  • Sharifi R, Morra R, Denise Appel C, Tallis M, Chioza B, Jankevicius G, Simpson MA, Matic I, Ozkan E, Golia B, Schellenberg MJ, Weston R, Williams JG, Rossi MN, Galehdari H, Krahn J, Wan A, Trembath RC, Crosby AH, Ahel D, Hay R, Ladurner AG, Timinszky G, Williams RS, Ahel I (2013). Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease. EMBO Journal. 2013 Mar 12

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Roman-Ulrich Müller

  • Bartram MP, Höhne M, Dafinger C, Völker LA, Albersmeyer M, Heiss J, Göbel H, Brönneke H, Burst V, Liebau MC, Benzing T, Schermer B, Müller RU (2013). Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT). J Mol Med. Jan. 2013
  • Burst V, Witthus M, Grundmann F, Müller RU, Kubacki T (2013). Optimal treatment of hyponatremia in clinical practice. Clinical Practice. Oct. 2013
  • Gharbi H, Fabretti F, Bharill P, Brinkkötter S, Burst V, Schermer B, Benzing T, Müller RU (2013). Loss of the Birt-Hogg-Dubé gene product Folliculin induces longevity in a hypoxia-inducible factor dependent manner. Aging Cell. Aug. 2013
  • Krebs CF, Kapffer S, Paust HJ, Schmidt T, Bennstein SB, Peters A, Stege G, Brix SR, Meyer-Schwesinger C, Müller RU, Turner JE, Steinmetz OM, Wolf G, Stahl RAK, Panzer U (2013). Micro-RNA-155 Drives TH17 Immune Response and Tissue Injury in Experimental Crescentic GN. J Am Soc Nephrol. Aug. 2013
  • Liebau MC, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller RU, Brodesser S, Saleem MA, Benzing T, Schermer B, Cybulla M, Kurschat CE (2013). Dysregulated autophagy contributes to podocyte damage in Fabry’s disease. PLoS ONE. May 2013
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU, Kurschat CE (2013). Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular aging. BMC Genomics. Aug. 2013

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Pierluigi Nicotera

  • Piyanova A, Albayram O, Rossi CA, Farwanah H, Michel K, Nicotera P, Sandhoff K, Bilkei-Gorzo A (2013). Loss of CB1 receptors leads to decreased cathepsin D levels and accelerated lipofuscin accumulation in the hippocampus. Mech Ageing Dev. 2013 Sep;134(9):391-9. doi: 10.1016/j.mad.2013.08.001. Epub 2013 Aug 13
  • Dimmeler S, Nicotera P (2013). MicroRNAs in age-related diseases. EMBO Mol Med. Feb;5(2):180-90. doi: 10.1002/emmm.201201986. Epub 2013 Jan 22

     

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Carien Niessen

  • Green KJ, Niessen CM, Godsel LM, Kulesz-Martin MF (2013). Montagna Symposium 2012: Keeping it all together--adhesion, the cytoskeleton, and signaling in morphogenesis and tissue function. J Invest Dermatol. 133:1124-8
  • Guenschmann C, Stachelscheid H, Akyüz MD, Schmitz A, Missero C, Brüning JC, Niessen CM (2013). IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. Developmental Cell. 26(2): 176-87
  • Mertz AF, Che Y, Banerjee S, Goldstein J, Rosowski KA, Revilla S, Niessen CM, Marchetti MC, Dufresne ER, Horsley V (2013). Intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A. 110: 842-7
  • Niessen MT, Scott J, Zielinski J, Vorhagen S, Blanpain C, Leitges M, Niessen CM (2013). The cell polarity protein aPKCl couples asymmetric divisions to cell fate decisions in the epidermal lineage. J Cell Biology. 202:887-900
  • Villani RM, Akyuz MD, Niessen MT, Niessen CM (2013). Analysis of bulge stem cells from the epidermis using flow cytometry. Methods Mol Biol. 989:33-43

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Angelika A. Noegel

  • Glöckner G, Noegel AA (2013). Comparative genomics in the Amoebozoa clade. Biol Rev Camb Philos Soc. 2013 Feb;88(1):215-25. doi: 10.1111/j.1469-185X.2012.00248.x. Epub 2012 Nov 8. Review
  • Hussain MS , Muhammad F, Bakhtiar SM, Inayat IA, Janzen E, Toliat MR, Eiberg H, Kjaer KW, Tommerup N, Noegel AA, Nürnberg P, Baig SM, Hansen L (2013). Genetic heterogeneity in Pakistani microcephaly families. Clinical Genetics. 83:446-451
  • Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Naeem T, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Nürnberg, P, Noegel AA (2013). CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 22:5199-5214
  • Müller R, Herr C, Sukumaran SK, Omosigho NN, Plomann M, Riyahi T Y, Stump, M, Swaminathan K, Tsangarides M, Yiannakou K, Blau-Wasser R, Gallinger C, Schleicher M, Kolanus W, Noegel AA (2013). The cytohesin paralog Sec7 of Dictyostelium discoideum is required for phagocytosis and cell motility. Cell Commun Signal. 11:54
  • Noegel AA, Glöckner G (2013). Dictyostelium Genomics: How it developed and what we have learned from it. Pharmazie. 68, 474–477
  • Pasham V, Rotte A, Mia S, Alesutan I, Chatterjee S, Hosseinzadeh Z, Bhandaru M, Noegel AA, Lang F (2013). Annexin 7 in the regulation of gastric acid secretion. Cell Physiol Biochem. 2013;32(6):1643-54. doi: 10.1159/000356600. Epub 2013 Dec 5
  • Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA (2013). Ablation of Cyclase Associated Protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. 70:527-543
  • Robery S, Tyson R, Dinh C, Kuspa A, Noegel AA, Bretschneider T, Andrews PL, Williams RS (2013). A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum. J Cell Sci. 2013 Dec 1;126(Pt 23):5465-76. doi: 10.1242/jcs.136440. Epub 2013 Sep 4
  • Sajid Hussain MS, Muhammad F, Bakhtiar SM, Inayat IA, Janzen E, Toliat MR, Eiberg H, Kjaer KW, Tommerup N, Noegel AA, Nürnberg P, Baig SM, Hansen L (2013). Genetic heterogeneity in Pakistani microcephaly families. Clinical Genetics. 83, 446-451
  • Yang L, Munck M, Swaminathan K, Kapinos LE, Noegel AA, Neumann S (2013). Mutations in LMNA modulate the Lamin A - Nesprin-2 interaction and cause LINC complex alterations. PLoS ONE. 8, e71850
  • Ziemann A, Hess S, Bhuwania R, Linder S, Kloppenburg P, Noegel AA, Clemen CS (2013). CRN2 enhances the invasiveness of glioblastoma cells. Neuro Oncol. 2013 May;15(5):548-61. doi: 10.1093/neuonc/nos388. Epub 2013 Feb 14

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Peter Nürnberg

  • Acevedo-Garcia J, Collins NC, Ahmadinejad N, Ma L, Houben A, Bednarek P, Benjdia M, Freialdenhoven A, Altmüller J, Nürnberg P, Reinhardt R, Schulze-Lefert P, Panstruga R (2013). Fine mapping and chromosome walking towards the Ror1 locus in barley (Hordeum vulgare L.). Theor Appl Genet. 2013 Dec;126(12):2969-82. Doi: 10.1007/s00122-013-2186-6. Epub 2013 Sep 17
  • Arélin M, Schulze B, Müller-Myhsok B, Horn D, Diers A, Uhlenberg B, Nürnberg P, Nürnberg G, Becker C, Mundlos S, Lindner TH, Sperling K, Hoffmann K (2013). Genome-wide linkage analysis is a powerful prenatal diagnostic tool in families with unknown genetic defects. Eur J Hum Genet. Apr;21(4):367-72. doi: 10.1038/ejhg.2012.198. Epub 2012 Oct 3
  • Arif B, Kumar KR, Seibler P, Vulinovic F, Fatima A, Winkler S, Nürnberg G, Thiele H, Nürnberg P, Jamil AZ, Brüggemann A, Abbas G, Klein C, Naz S, Lohmann K (2013). A Novel OPA3 Mutation Revealed by Exome Sequencing: An Example of Reverse Phenotyping. JAMA Neurol. Jun 1;70(6):783-7. doi: 10.1001/jamaneurol.2013.1174
  • Basel-Vanagaite L, Hershkovitz T, Heyman E, Raspall-Chaure M, Kakar N, Smirin-Yosef P, Vila-Pueyo M, Kornreich L, Thiele H, Bode H, Lagovsky I, Dahary D, Haviv A, Hubshman MW, Pasmanik-Chor M, Nürnberg P, Gothelf D, Kubisch C, Shohat M, Macaya A, Borck G (2013). Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum. Am J Hum Genet. 2013 Sep 5;93(3):524-9. doi: 10.1016/j.ajhg.2013.07.005. Epub 2013 Aug 8
  • Beetz C, Johnson A, Schuh AL, Thakur S, Varga RE, Fothergill T, Hertel N, Bomba-Warczak E, Thiele H, Nürnberg G, Altmüller J, Saxena R, Chapman ER, Dent EW, Nürnberg P, Audhya A (2013). Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure. Proc Natl Acad Sci U S A. Mar 26;110(13):5091-6. doi: 10.1073/pnas.1217197110. Epub 2013 Mar 11
  • Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, Anderson R, Hahn A, Innes AM, Suchowersky O, Mets MB, Nürnberg G, McLeod DR, Thiele H, Waggoner D, Altmüller J, Boycott KM, Schoser B, Nürnberg P, Ober C, Heller R, Parboosingh JS, Wollnik B, Sacher M, Lamont RE (2013). Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet. 2013 Jul 11;93(1):181-90. doi: 10.1016/j.ajhg.2013.05.028. Epub 2013 Jul 3
  • Cirak S, Foley AR, Herrmann R, Willer T, Yau S, Stevens E, Torelli S, Brodd L, Kamynina A, Vondracek P, Roper H, Longman C, Korinthenberg R, Marrosu G, Nürnberg P, UK10K Consortium, Michele DE, Plagnol V, Hurles M, Moore SA, Sewry CA, Campbell KP, Voit T, Muntoni F (2013). ISPD gene mutations are a common cause of congenital and limb-girdle muscular dystrophies. Brain. Jan;136(Pt 1):269-81. doi: 10.1093/brain/aws312. Epub 2013 Jan 3
  • Clinical Lung Cancer Genome Project (CLCGP); Network Genomic Medicine (NGM) (2013). A genomics-based classification of human lung tumors. Sci Transl Med. 2013 Oct 30;5(209):209ra153. doi: 10.1126/scitranslmed.3006802
  • Eckl KM, Tidhar R, Thiele H, Oji V, Hausser I, Brodesser S, Preil ML, Onal-Akan A, Stock F, Müller D, Becker K, Casper R, Nürnberg G, Altmüller J, Nürnberg P, Traupe H, Futerman AH, Hennies HC (2013). Impaired epidermal ceramide synthesis causes autosomal recessive congenital ichthyosis and reveals the importance of ceramide acyl chain length. J Invest Dermatol. 2013 Sep;133(9):2202-11. doi: 10.1038/jid.2013.153. Epub 2013 Apr 2
  • Eckl KM, Tidhar R, Thiele H, Oji V, Hausser I, Brodesser S, Preil ML, Onal-Akan A, Stock F, Müller D, Becker K, Casper R, Nürnberg G, Altmüller J, Nürnberg P, Traupe H, Futerman AH, Hennies HC (2013). Impaired Epidermal Ceramide Synthesis Causes Autosomal Recessive Congenital Ichthyosis and Reveals the Importance of Ceramide Acyl Chain Length. J Invest Dermatol. Apr 2. doi: 10.1038/jid.2013.153. Epub 2013 Apr 2
  • Elfimova N, Sievers E, Eischeid H, Kwiecinski M, Noetel A, Hunt H, Becker D, Frommolt P, Quasdorff M, Steffen HM, Nürnberg P, Büttner R, Teufel A, Dienes HP, Drebber U, Odenthal M (2013). Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration. Biochim Biophys Acta. May;1833(5):1190-8. doi: 10.1016/j.bbamcr.2013.01.023. Epub 2013 Feb 5
  • Frank V, Habbig S, Bartram MP, Eisenberger T, Veenstra-Knol HE, Decker C, Boorsma RA, Göbel H, Nürnberg G, Griessmann A, Franke M, Borgal L, Kohli P, Völker LA, Dötsch J, Nürnberg P, Benzing T, Bolz HJ, Johnson C, Gerkes EH, Schermer B, Bergmann C (2013). Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. Hum Mol Genet. Jun 1;22(11):2177-85. doi: 10.1093/hmg/ddt070. Epub 2013 Feb 14
  • Gee HY, Otto EA, Hurd TW, Ashraf S, Chaki M, Cluckey A, Vega-Warner V, Saisawat P, Diaz KA, Fang H, Kohl S, Allen SJ, Airik R, Zhou W, Ramaswami G, Janssen S, Fu C, Innis JL, Weber S, Vester U, Davis EE, Katsanis N, Fathy HM, Jeck N, Klaus G, Nayir A, Rahim KA, Attrach IA, Hassoun IA, Ozturk S, Drozdz D, Helmchen U, O'Toole JF, Attanasio M, Lewis RA, Nürnberg G, Nürnberg P, Washburn J, Macdonald J, Innis JW, Levy S, Hildebrandt F (2013). Whole-exome resequencing distinguishes cystic kidney diseases from phenocopies in renal ciliopathies. Kidney Int. 2013 Nov 20. doi: 10.1038/ki.2013.450. Published online 2013 Nov 20
  • Grosch M, Grüner B, Spranger S, Stütz AM, Rausch T, Korbel JO, Seelow D, Nürnberg P, Sticht H, Lausch E, Zabel B, Winterpacht A, Tagariello A (2013). Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype. Matrix Biol. 2013 Oct-Nov;32(7-8):387-92. Doi: 10.1016/j.matbio.2013.05.001. Epub 2013 May 9
  • Grosch M, Grüner B, Spranger S, Stütz AM, Rausch T, Korbel JO, Seelow D, Nürnberg P, Sticht H, Lausch E, Zabel B, Winterpacht A, Tagariello A (2013). Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype. Matrix Biol. May 9. doi:pii: S0945-053X(13)00070-X. 10.1016/j.matbio.2013.05.001. Epub 2013 May 9
  • Hämmerer D, Biele G, Müller V, Thiele H, Nürnberg P, Heekeren HR, Li SC (2013). Effects of PPP1R1B (DARPP-32) Polymorphism on Feedback-Related Brain Potentials Across the Life Span. Front Psychol. ;4:89. doi: 10.3389/fpsyg.2013.00089. Epub 2013 Mar 4
  • Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Khan TN, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Neubauer BA, Nürnberg P, Noegel AA (2013). CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013 Dec 20;22(25):5199-214. doi: 10.1093/hmg/ddt374. Epub 2013 Aug 4
  • Koehler K, Malik M, Mahmood S, Gießelmann S, Beetz C, Hennings JC, Huebner AK, Grahn A, Reunert J, Nürnberg G, Thiele H, Altmüller J, Nürnberg P, Mumtaz R, Babovic-Vuksanovic D, Basel-Vanagaite L, Borck G, Brämswig J, Mühlenberg R, Sarda P, Sikiric A, Anyane-Yeboa K, Zeharia A, Ahmad A, Coubes C, Wada Y, Marquardt T, Vanderschaeghe D, Van Schaftingen E, Kurth I, Huebner A, Hübner CA (2013). Mutations in GMPPA cause a glycosylation disorder characterized by intellectual disability and autonomic dysfunction. Am J Hum Genet. 2013 Oct 3;93(4):727-34. doi: 10.1016/j.ajhg.2013.08.002. Epub 2013 Sep 12
  • Lal D, Trucks H, Møller RS, Hjalgrim H, Koeleman BP, de Kovel CG, Visscher F, Weber YG, Lerche H, Becker F, Schankin CJ, Neubauer BA, Surges R, Kunz WS, Zimprich F, Franke A, Illig T, Ried JS, Leu C, Nürnberg P, Sander T; EMINet Consortium; EPICURE Consortium (2013). Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy. Epilepsia. Feb;54(2):265-71. doi: 10.1111/epi.12084. Epub 2013 Jan 25
  • Lal D, Becker K, Motameny S, Altmüller J, Thiele H, Nürnberg P, Ahting U, Rolinski B, Neubauer BA, Hahn A (2013). Homozygous missense mutation of NDUFV1 as the cause of infantile bilateral striatal necrosis. Neurogenetics. Feb;14(1):85-7. doi: 10.1007/s10048-013-0355-z. Epub 2013 Jan 20
  • Lao O, Altena E, Becker C, Brauer S, Kraaijenbrink T, van Oven M, Nürnberg P, de Knijff P, Kayser M (2013). Clinal distribution of human genomic diversity across the Netherlands despite archaeological evidence for genetic discontinuities in Dutch population history. Investig Genet. May 20;4(1):9
  • Leipold E, Liebmann L, Korenke GC, Heinrich T, Giesselmann S, Baets J, Ebbinghaus M, Goral RO, Stödberg T, Hennings JC, Bergmann M, Altmüller J, Thiele H, Wetzel A, Nürnberg P, Timmerman V, De Jonghe P, Blum R, Schaible HG, Weis J, Heinemann SH, Hübner CA, Kurth I (2013). A de novo gain-of-function mutation in SCN11A causes loss of pain perception. Nat Genet. 2013 Nov;45(11):1399-404. doi: 10.1038/ng.2767. Epub 2013 Sep 15
  • Lemaire M, Frémeaux-Bacchi V, Schaefer F, Choi M, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Martinez F, Ji W, Overton JD, Mane SM, Nürnberg G, Altmüller J, Thiele H, Morin D, Deschenes G, Baudouin V, Llanas B, Collard L, Majid MA, Simkova E, Nürnberg P, Rioux-Leclerc N, Moeckel GW, Gubler MC, Hwa J, Loirat C, Lifton RP (2013). Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome. Nat Genet. May;45(5):531-6. doi: 10.1038/ng.2590. Epub 2013 Mar 31
  • Lemke JR, Lal D, Reinthaler EM, Steiner I, Nothnagel M, Alber M, Geider K, Laube B, Schwake M, Finsterwalder K, Franke A, Schilhabel M, Jähn JA, Muhle H, Boor R, Van Paesschen W, Caraballo R, Fejerman N, Weckhuysen S, De Jonghe P, Larsen J, Møller RS, Hjalgrim H, Addis L, Tang S, Hughes E, Pal DK, Veri K, Vaher U, Talvik T, Dimova P, Guerrero López R, Serratosa JM, Linnankivi T, Lehesjoki AE, Ruf S, Wolff M, Buerki S, Wohlrab G, Kroell J, Datta AN, Fiedler B, Kurlemann G, Kluger G, Hahn A, Haberlandt DE, Kutzer C, Sperner J, Becker F, Weber YG, Feucht M, Steinböck H, Neophythou B, Ronen GM, Gruber-Sedlmayr U, Geldner J, Harvey RJ, Hoffmann P, Herms S, Altmüller J, Toliat MR, Thiele H, Nürnberg P, Wilhelm C, Stephani U, Helbig I, Lerche H, Zimprich F, Neubauer BA, Biskup S, von Spiczak S (2013). Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nat Genet. 2013 Sep;45(9):1067-72. doi: 10.1038/ng.2728. Epub 2013 Aug 11
  • Møller RS, Weber YG, Klitten LL, Trucks H, Muhle H, Kunz WS, Mefford HC, Franke A, Kautza M, Wolf P, Dennig D, Schreiber S, Rückert IM, Wichmann HE, Ernst JP, Schurmann C, Grabe HJ, Tommerup N, Stephani U, Lerche H, Hjalgrim H, Helbig I, Sander T; EPICURE Consortium (2013). Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy. Epilepsia. Feb;54(2):256-64. doi: 10.1111/epi.12078. Epub 2013 Jan 7
  • Noetel A, Elfimova N, Altmüller J, Becker C, Becker D, Lahr W, Nürnberg P, Wasmuth H, Teufel A, Büttner R, Dienes HP, Odenthal M (2013). Next generation sequencing of the Ago2 interacting transcriptome identified chemokine family members as novel targets of neuronal microRNAs in hepatic stellate cells. J Hepatol. Feb;58(2):335-41. doi: 10.1016/j.jhep.2012.09.024. Epub 2012 Oct 4
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU, Kurschat CE (2013). Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging. BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559
  • Schiffer PH, Kroiher M, Kraus C, Koutsovoulos GD, Kumar S, Camps JI, Nsah NA, Stappert D, Morris K, Heger P, Altmüller J, Frommolt P, Nürnberg P, Thomas WK, Blaxter ML, Schierenberg E (2013). The genome of Romanomermis culicivorax: revealing fundamental changes in the core developmental genetic toolkit in Nematoda. BMC Genomics. 2013 Dec 27;14:923. doi: 10.1186/1471-2164-14-923
  • Stölting G, Teodorescu G, Begemann B, Schubert J, Nabbout R, Toliat MR, Sander T, Nürnberg P, Lerche H, Fahlke C (2013). Regulation of ClC-2 gating by intracellular ATP. Pflugers Arch. 2013 Oct;465(10):1423-37. doi: 10.1007/s00424-013-1286-0. Epub 2013 May 1
  • Stölting G, Teodorescu G, Begemann B, Schubert J, Nabbout R, Toliat MR, Sander T, Nürnberg P, Lerche H, Fahlke C (2013). Regulation of ClC-2 gating by intracellular ATP. Pflugers Arch. May 1. Epub 2013 May 1
  • Varga RE, Schüle R, Fadel H, Valenzuela I, Speziani F, Gonzalez M, Rudenskaia G, Nürnberg G, Thiele H, Altmüller J, Alvarez V, Gamez J, Garbern JY, Nürnberg P, Zuchner S, Beetz C (2013). Do Not Trust the Pedigree: Reduced and Sex-Dependent Penetrance at a Novel Mutation Hotspot in ATL1 Blurs Autosomal Dominant Inheritance of Spastic Paraplegia. Hum Mutat. Jun;34(6):860-3. doi: 10.1002/humu.22309. Epub 2013 Apr 5
  • Weterman MA, Barth PG, van Spaendonck-Zwarts KY, Aronica E, Poll-The BT, Brouwer OF, van Tintelen JP, Qahar Z, Bradley EJ, de Wissel M, Salviati L, Angelini C, van den Heuvel L, Thomasse YE, Backx AP, Nürnberg G, Nürnberg P, Baas F (2013). Recessive MYL2 mutations cause infantile type I muscle fibre disease and cardiomyopathy. Brain. Jan;136(Pt 1):282-93. doi: 10.1093/brain/aws293
  • Wieczorek D, Bögershausen N, Beleggia F, Steiner-Haldenstätt S, Pohl E, Li Y, Milz E, Martin M, Thiele H, Altmüller J, Alanay Y, Kayserili H, Klein-Hitpass L, Böhringer S, Wollstein A, Albrecht B, Boduroglu K, Caliebe A, Chrzanowska K, Cogulu O, Cristofoli F, Czeschik JC, Devriendt K, Dotti MT, Elcioglu N, Gener B, Goecke TO, Krajewska-Walasek M, Guillén-Navarro E, Hayek J, Houge G, Kilic E, Simsek-Kiper PÖ, López-González V, Kuechler A, Lyonnet S, Mari F, Marozza A, Mathieu Dramard M, Mikat B, Morin G, Morice-Picard F, Ozkinay F, Rauch A, Renieri A, Tinschert S, Utine GE, Vilain C, Vivarelli R, Zweier C, Nürnberg P, Rahmann S, Vermeesch J, Lüdecke HJ, Zeschnigk M, Wollnik B (2013). A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling. Hum Mol Genet. 2013 Dec 20;22(25):5121-35. doi: 10.1093/hmg/ddt366. Epub 2013 Aug 1
  • Wirschell M, Olbrich H, Werner C, Tritschler D, Bower R, Sale WS, Loges NT, Pennekamp P, Lindberg S, Stenram U, Carlén B, Horak E, Köhler G, Nürnberg P, Nürnberg G, Porter ME, Omran H (2013). The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans. Nat Genet. Mar;45(3):262-8. doi: 10.1038/ng.2533. Epub 2013 Jan 27

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Linda Partridge

  • Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, Krieg T, Brookes PS, Murphy MP (2013). Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med. Jun;19(6):753-9. doi: 10.1038/nm.3212. Epub 2013 May 26
  • Gems D, Partridge L (2013). Genetics of longevity in model organisms: debates and paradigm shifts. Annu Rev Physiol. ;75:621-44. doi: 10.1146/annurev-physiol-030212-183712. Epub 2012 Nov 26
  • Lee SF, Eyre-Walker YC, Rane RV, Reuter C, Vinti G, Rako L, Partridge L, Hoffmann AA (2013). Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster. Mol Ecol. May;22(10):2716-25. doi: 10.1111/mec.12301. Epub 2013 Mar 18
  • López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G (2013). The hallmarks of aging. Cell. Jun 6;153(6):1194-217. doi: 10.1016/j.cell.2013.05.039
  • Metaxakis A, Partridge L (2013). Dietary restriction extends lifespan in wild-derived populations of Drosophila melanogaster. PLoS ONE. 8, e74681
  • Regan JC, Partridge L (2013). Gender and longevity: why do men die earlier than women? Comparative and experimental evidence. Best Pract Res Clin Endocrinol Metab. 2013 Aug;27(4):467-79. doi: 10.1016/j.beem.2013.05.016. Epub 2013 Jun 22
  • Slack C, Partridge L (2013). Genes, pathways and metabolism in ageing. Drug Discovery Today. Disease Models 10, e87-e93
  • Wredenberg A, Lagouge M, Bratic A, Metodiev MD, Spåhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, Habermann B, Partridge L, Park CB, Larsson NG (2013). MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet. ;9(1):e1003178. doi: 10.1371/journal.pgen.1003178. Epub 2013 Jan 3

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Manolis Pasparakis

  • Becker S, Oelschlaeger TA, Wullaert A, Pasparakis M, Wehkamp J, Stange EF, Gersemann M (2013). Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo. PLoS One. 8(2):e55620
  • Kumari S, Bonnet MC, Ulvmar MH, Wolk K, Karagianni N, Witte E, Uthoff-Hachenberg C, Renauld JC, Kollias G, Toftgard R, Sabat R, Pasparakis M, Haase I (2013). Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice. Immunity. 39(5):899-911
  • Linares JF, Duran A, Yajima T, Pasparakis M, Moscat J, Diaz-Meco MT (2013). K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells. Mol Cell. 51, 283-96
  • Perez-Nazario N, Rangel-Moreno J, O'Reilly MA, Pasparakis M, Gigliotti F, Wright TW (2013). Selective Ablation of Lung Epithelial IKK2 Impairs Pulmonary Th17 Responses and Delays the Clearance of Pneumocystis. J Immunol. 191(9):4720-30
  • Rastrick JM, Stevenson CS, Eltom S, Grace M, Davies M, Kilty I, Evans SM, Pasparakis M, Catley MC, Lawrence T, Adcock IM, Belvisi MG, Birrell MA (2013). Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling. PLoS One. 2013;8(1):e54128

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Mats Paulsson

  • Abari E, Kociok N, Hartmann U, Semkova I, Paulsson M, Joussen AM (2013). Alterations in basement membrane immunoreactivity of the diabetic retina in three diabetic mouse models. Graefe´s Arch Clin Exp Ophthalmol. 251, 763-775
  • Agarwal P, Schulz JN, Blumbach K, Andreasson K, Heinegård D, Paulsson M, Mauch C, Eming SA, Eckes B, Krieg T (2013). Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies. Matrix Biol. Mar 15.  32, 325-331
  • Etich J, Bergmeier V, Frie C, Kreft S, Bengestrate L, Eming S, Mauch C, Eckes B, Ulus H, Lund FE, Rappl G, Abken H, Paulsson M, Brachvogel B (2013). PECAM1(+)/Sca1(+)/CD38(+) vascular cells transform into myofibroblast-like cells in skin wound repair. PLoS One. ;8(1):e53262. doi: 10.1371/journal.pone.0053262. Epub 2013 Jan 4
  • Hartmann U, Hülsmann H, Seul J, Röll S, Midani H, Breloy I, Hechler D, Müller R, Paulsson M (2013). Testican-3: a brain-specific proteoglycan member of the BM-40/SPARC/osteonectin family. J Neurochem. May;125(3):399-409. doi: 10.1111/jnc.12212. Epub 2013 Mar 13
  • Klatt AR, Paul-Klausch B, Klinger G, Hillebrand U, Kühn G, Kobbe B, Renno JH, Johannis W, Paulsson M, Wagener R (2013). The matrilin-3 VWA1 domain modulates interleukin-6 release from primary human chondrocytes. Osteoarthr Cartilage. 21, 869-873
  • Schael S, Nüchel J, Müller S, Petermann P, Kormann J, Pérez-Otaño I, Martínez SM, Paulsson M, Plomann M (2013). Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation. J Biol Chem. Mar 29;288(13):9303-12. doi: 10.1074/jbc.M113.461293. Epub 2013 Feb 18

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Alvaro Rada-Iglesias

  • Rada-Iglesias A, Prescott SL, Wysocka, J (2013). Human genetic variation within neural crest enhancers: molecular and phenotypic implications. Philos Trans R Soc Lond B Biol Sci. May 368, 20120360
  • Rada-Iglesias A (2013). Pioneering barren land: mitotic bookmarking by transcription factors. Dev Cell. Feb 25;24(4):342-4

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Hans Christian Reinhardt

  • Höpker K, Reinhardt HC (2013). p53-regulating pathways as targets for personalized cancer therapy. Dtsch Med Wochenschr. 2013 Jan;138(3):82-6. doi: 10.1055/s-0032-1327380
  • Malchers F, Dietlein F, Schöttle J, Lu X, Nogova L, Albus K, Fernandez-Cuesta L, Heuckmann JM, Gautschi O, Diebold J, Plenker D, Gardizi M, Scheffler M, Bos M, Seidel D, Leenders F, Richters A, Peifer M, Florin A, Mainkar PS, Karre N, Chandrasekhar S, George J, Silling S, Rauh D, Zander T, Ullrich R, Reinhardt HC, Ringeisen F, Büttner R, Heukamp LC, Wolf J, Thomas RK (2013). Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer. Cancer Discovery. Published Online First December 3, 2013; doi:10.1158/2159-8290
  • Morandell S, Reinhardt HC, Cannell IG, Kim JS, Ruf DM, Jacks T, Yaffe MB (2013). A novel Cre-versible approach identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo. Cell Reports. 2013 Nov 13. doi:pii: S2211-1247(13)00609-8. 10.1016/j.celrep.2013.10.025
  • Reinhardt HC, Yaffe MB (2013). Phosphoserine/threonine binding domains: navigating the cell cycle and DNA damage response. Nat Rev Mol Cell Biol. 2013 Sep;14(9):563-80
  • Riabinska A, Daheim M, Herter-Sprie GS, Winkler J, Fritz C, Hallek M, Thomas RK, Kreuzer KA, Frenzel LP, Monfared P, Martins-Boucas JM, Chen S, Reinhardt HC (2013). Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors. Sci Transl Med. 2013 Jun 12;5(189):189ra78. doi: 10.1126/scitranslmed.3005814

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Nirmal Robinson

  • Nguyen T, Robinson N, Allison SE, Coombes BK, Sad S, Krishnan L (2013). IL-10 produced by trophoblast cells inhibits phagosome maturation leading to profound intracellular proliferation of Salmonella enterica Typhimurium. Placenta. 34(9):765-774

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Bernhard Schermer

  • Bartram M, Höhne M, Dafinger C, Völker L, Albersmeyer M, Heiss J, Göbel H, Brönneke H, Burst V, Liebau M, Benzing T, Schermer B, Müller R (2013). Conditional loss of kidney microRNAs results in congenital anomalies of the kidney and urinary tract (CAKUT). J Mol Med. 91: 739–48
  • Frank V, Habbig S, Bartram M, Eisenberger T, Veenstra-Knol H, Decker C, Boorsma R, Göbel H, Nürnberg G, Griessmann A, Franke M, Borgal L, Kohli P, Völker L, Dötsch J, Nürnberg P, Benzing T, Bolz H, Johnson C, Gerkes E, Schermer B, Bergmann C (2013). Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. Hum Mol Genet. 22: 2177–85
  • Gharbi H, Fabretti F, Bharill P, Rinschen M, Brinkkötter S, Frommolt P, Burst V, Schermer B, Benzing T, Müller R (2013). Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. Aging Cell. 12: 593–603
  • Habbig S, Frank V, Bartram M, Goebel H, Benzing T, Schermer B, Bergmann C (2013). First evidence of NPHP9 null-mutations in humans resulting in renal-pancreato-hepatic dysplasia. Pediatr Nephrol. 28: 1539–1539
  • Hackl M, Burford J, Villanueva K, Lam L, Suszták K, Schermer B, Benzing T, Peti-Peterdi J (2013). Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med. 19: 1661–6
  • Höhne M, Ising C, Hagmann H, Völker L, Brähler S, Schermer B, Brinkkoetter P, Benzing T (2013). Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. Am J Pathol. 182: 332–8
  • Liebau M, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller R, Brodesser S, Saleem M, Benzing T, Schermer B, Cybulla M, Kurschat C (2013). Dysregulated autophagy contributes to podocyte damage in Fabry’s disease. PLoS ONE. 8: e63506
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze J, Roodbergen M, Hoeijmakers J, Schumacher B, Nürnberg P, Dollé M, Benzing T, Müller R, Kurschat C (2013). Transcriptional profiling reveals progeroid Ercc1(-/?) mice as a model system for glomerular aging. BMC Genomics. 14: 559
  • Völker L, Schurek E, Rinschen M, Tax J, Schutte B, Lamkemeyer T, Ungrue D, Schermer B, Benzing T, Höhne M (2013). Characterization of a short isoform of the kidney protein podocin in human kidney. BMC Nephrol. 14: 102

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Markus Schubert

  • Franko A, von Kleist-Retzow JC, Neschen S, Wu M, Schommers P, Böse M, Kunze A, Hartmann U, Sanchez-Lasheras C, Stoehr O, Huntgeburth M, Brodesser S, Irmler M, Beckers J, de Angelis MH, Paulsson M, Schubert M, Wiesner RJ (2013). Liver adapts mitochondrial function to insulin resistant and diabetic states in mice. J Hepatol. 2013 Nov 28. pii: S0168-8278(13)00821-0. Doi: 10.1016/j.jhep.2013.11.020. Epub 2013 Nov 28
  • Hookham MB, O'Donovan HC, Church RH, Mercier-Zuber A, Luzi L, Curran SP, Carew RM, Droguett A, Mezzano S, Schubert M, White MF, Crean JK, Brazil DP (2013). Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy. FEBS J. 2013 Jul;280(14):3232-43. doi: 10.1111/febs.12305. Epub 2013 May 29
  • Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M (2013). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. Age (Dordr). Feb;35(1):83-101. doi: 10.1007/s11357-011-9333-2. Epub 2011 Nov 6

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Björn Schumacher

  • Ermolaeva M, Schumacher B (2013).
 The innate immune system as mediator of systemic DNA damage responses. Commun Integr Biol. 2013 Nov 13;6(6):e26926. doi: 10.4161/cib.26926
  • Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B (2013). DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature. 2013 Sep 19;501(7467):416-20. doi: 10.1038/nature12452
  • Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU, Kurschat CE (2013). Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular aging. BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559
  • Wolters S, Schumacher B (2013). Genome maintenance and transcription integrity in aging and disease. Front Genet. 2013 Feb 25; 4:19

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Günter Schwarz

  • Belaidi AA, Schwarz G (2013). Molybdenum cofactor deficiency: metabolic link between taurine and s-sulfocysteine. Adv Exp Med Biol. 776:13-9
  • Belaidi AA, Schwarz G (2013). Metal insertion into the molybdenum cofactor: product-substrate channeling demonstrates the functional origin of domain fusion in gephyrin. Biochem J. 450: 149-57
  • Clinch K, Watt DK, Dixon RA, Baars SM, Gainsford GJ, Tiwari A, Schwarz G, Saotome Y, Storek M, Belaidi AA, Santamaria-Araujo JA (2013). Synthesis of Cyclic Pyranopterin Monophosphate, a Biosynthetic Intermediate in the Molybdenum Cofactor Pathway. J Med Chem. 2013 Feb 28;56(4):1730-8. doi: 10.1021/jm301855r. Epub 2013 Feb 19
  • Kalimuthu P, Fischer-Schrader K, Schwarz G, Bernhardt PV(2013). Mediated Electrochemistry of Nitrate Reductase from Arabidopsis thaliana. J Phys Chem B. 2013 Jun 27;117(25):7569-77. doi: 10.1021/jp404076w. Epub 2013 Jun 12
  • Kowalczyk S, Winkelmann A, Smolinsky B, Förstera B, Neundorf I, Schwarz G, Meier JC (2013). Direct binding of GABAA receptor β2 and β3 subunits to gephyrin. Eur J Neurosci. 37:544-54
  • Schwarz G, Belaidi AA (2013). Molybdenum in human health and disease. Met Ions Life Sci. 13:415-50

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Philipp Steven

  • Bock F, Maruyama K, Regenfuss B, Hos D, Steven P, Heindl LM, Cursiefen C (2013). Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res. 2013 May;34:89-124. doi:10.1016/j.preteyeres.2013.01.001. Epub 2013 Jan 22
  • Siebelmann S, Gehlsen U, Hüttmann G, Koop N, Bölke T, Gebert A, Stern ME, Niederkorn JY, Steven P (2013). Development, alteration and real time dynamics of conjunctiva-associated lymphoid tissue. PLoS One. 2013 Dec 20;8(12):e82355
  • Steven P, Le Blanc C, Velten K, Lankenau E, Krug M, Oelckers S, Heindl LM, Gehlsen U, Hüttmann G, Cursiefen C (2013). Optimizing descemet membrane endothelial keratoplasty using intraoperative optical coherence tomography. JAMA Ophthalmol. 2013 Sep;131(9):1135-42. doi: 10.1001/jamaophthalmol.2013.4672

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Aleksandra Trifunovic

  • Pujol C, Bratic-Hench I, Sumakovic M, Hench J, Mourier A, Baumann L, Pavlenko V, Trifunovic A (2013). Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant. PLoS One. ;8(3):e59493. doi: 10.1371/journal.pone.0059493. Epub 2013 Mar 28

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Mirka Uhlirova

  • Külshammer E, Uhlirova M (2013). The actin cross-linker Filamin/Cheerio mediates tumor malignancy downstream of JNK signaling. J Cell Sci. Feb 15;126(Pt 4):927-38. doi: 10.1242/jcs.114462. Epub 2012 Dec 13

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David Vilchez

  • Vilchez D, Boyer L, Lutz M, Merkwirth C, Morantte I, Tse C, Spencer B, Page L, Masliah E, Berggren WT, Gage FH, Dillin A (2013). FOXO4 is necessary for neural differentiation of human embryonic stem cells. Aging Cell. 12(3): 518-522

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Sara Wickström

  • Ghatak S, Morgner J, Wickström SA (2013). ILK: a pseudokinase with a unique function in the integrin-actin linkage. Biochem Soc Trans. 41, 995-1001
  • Malan D, Elischer A, Hesse M, Wickström SA, Fleischmann BK, Bloch W (2013). Deletion of the integrin-linked kinase impairs endothelial cell development and function due to defective caveolar-based signaling. Development. 140, 987-95
  • Morgner J, Wickström SA (2013). The weakest link: A new paradigm for stabilizing the integrin-actin connection. Cell Cycle. 12, 2929-2930
  • Radovanac K, Morgner J, Schultz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA (2013). Stabilization of Integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. EMBO J. 32, 1409-1424
  • Traub S, Morgner J, Martino MM, Höning S, Swartz M, Wickström SA, Hubbell JA, Eming SA (2013). The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials. 34, 5958-5968
  • Zanivan S, Meves A, Behrendt K, Schoof EM, Neilson LJ, Tang HR, Cox J, van Ree JH, van Deursen JM, Trempus CS, Machesky L, Linding R, Wickström SA, Fässler R, Mann M (2013). In vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis. Cell Reports. 21, 552-66

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Rudolf J. Wiesner

  • Franko A, Baris O, Bergschneider AE, von Toerne C, Hauck SM, Aichler M, Walch AK, Wurst W, Wiesner RJ, Johnston ICD, Hrabĕ de Angelis M (2013). Efficient isolation of pure and functional mitochondria from mouse tissue using automated tissue disruption and enrichment with anti-TOM22 magnetic beads. PLoS One Dec. 12;8(12):e82392. doi: 10.1371/journal.pone.0082392
  • Renne U, Langhammer M, Brenmoehl J, Walz C, Zeissler A, Tuchscherer A, Piechotta M, Wiesner RJ, Bielohuby M, Hoeflich A (2013). Lifelong polygenic obesity prevents age- and diet-induced glucose intolerance in mice – obesity is no road to the dysmetabolic phenotype. PLoS One. Nov 13;8(11):e79788. doi: 10.1371/journal.pone.0079788
  • Sobek S, Dalla Rosa I, Pommier Y, Bornholz B, Kalfalah F, Zhang H, Wiesner RJ, von Kleist-Retzow JC, Hillebrand F, Schaal H, Mielke C, Christensen MO, Boege F (2013). Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I. Nuc Acid Res. 41, 9848-57
  • Wiesner RJ (2013). It´s all in brain - 2 neurons mediate increased life span upon various stressors in C. elegans (Comment). Mol Metab. 2, 62    

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Andreas Wodarz

  • Zhang G, Beati H, Nilsson J, Wodarz A (2013). The Drosophila microtubule-associated protein Mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region. PLoS ONE. 8, e60596. doi:10.1371/journal.pone.0060596

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Bernd Wollnik

  • Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Khan TN, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Neubauer BA, Nürnberg P, Noegel AA (2013). CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013 Dec 20;22(25):5199-214. doi: 10.1093/hmg/ddt374. Epub 2013 Aug 4
  • Wieczorek D, Bögershausen N, Beleggia F, Steiner-Haldenstätt S, Pohl E, Li Y, Milz E, Martin M, Thiele H, Altmüller J, Alanay Y, Kayserili H, Klein-Hitpass L, Böhringer S, Wollstein A, Albrecht B, Boduroglu K, Caliebe A, Chrzanowska K, Cogulu O, Cristofoli F, Czeschik JC, Devriendt K, Dotti MT, Elcioglu N, Gener B, Goecke TO, Krajewska-Walasek M, Guillén-Navarro E, Hayek J, Houge G, Kilic E, Simsek-Kiper PÖ, López-González V, Kuechler A, Lyonnet S, Mari F, Marozza A, Mathieu Dramard M, Mikat B, Morin G, Morice-Picard F, Ozkinay F, Rauch A, Renieri A, Tinschert S, Utine GE, Vilain C, Vivarelli R, Zweier C, Nürnberg P, Rahmann S, Vermeesch J, Lüdecke HJ, Zeschnigk M, Wollnik B (2013). A comprehensive molecular study on Coffin-Siris and Nicolaides-Baraitser syndromes identifies a broad molecular and clinical spectrum converging on altered chromatin remodeling. Hum Mol Genet. 2013 Dec 20;22(25):5121-35. doi: 10.1093/hmg/ddt366. Epub 2013 Aug 1
  • Zweier C, Kraus C, Brueton L, Cole T, Degenhardt F, Engels H, Gillessen-Kaesbach G, Graul-Neumann L, Horn D, Hoyer J, Just W, Rauch A, Reis A, Wollnik B, Zeschnigk M, Lüdecke HJ, Wieczorek D (2013). A new face of Borjeson-Forssman-Lehmann syndrome? De novo mutations in PHF6 in seven females with a distinct phenotype. J Med Genet. 2013 Dec;50(12):838-47. doi: 10.1136/jmedgenet-2013-101918. Epub 2013 Oct 3
  • Hoyer-Kuhn H, Semler O, Garbes L, Zimmermann K, Becker J, Wollnik B, Schoenau E, Netzer C (2013). A Non-Classical IFITM5 Mutation Located in the Coding Region Causes Severe Osteogenesis Imperfecta with Prenatal Onset. J Bone Miner Res. 2013 Nov 30. doi: 10.1002/jbmr.2156
  • Pohl E, Aykut A, Beleggia F, Karaca E, Durmaz B, Keupp K, Arslan E, Palamar M, Yigit G, Özkinay F, Wollnik B (2013). A hypofunctional PAX1 mutation causes autosomal recessively inherited otofaciocervical syndrome. Hum Genet. 2013 Nov;132(11):1311-20. doi: 10.1007/s00439-013-1337-9. Epub 2013 Jul 13. Erratum in: Hum Genet. 2013 Nov;132(11):1321. Onay, Melis Palamar [corrected to Palamar, Melis]
  • Keupp K, Li Y, Vargel I, Hoischen A, Richardson R, Neveling K, Alanay Y, Uz E, Elcioğlu N, Rachwalski M, Kamaci S, Tunçbilek G, Akin B, Grötzinger J, Konas E, Mavili E, Müller-Newen G, Collmann H, Roscioli T, Buckley MF, Yigit G, Gilissen C, Kress W, Veltman J, Hammerschmidt M, Akarsu NA, Wollnik B (2013). Mutations in the interleukin receptor IL11RA cause autosomal recessive Crouzon-like craniosynostosis. Mol Genet Genomic Med. 2013 Nov;1(4):223-37. doi: 10.1002/mgg3.28. Epub 2013 Aug 19
  • Dimopoulou A, Fischer B, Gardeitchik T, Schröter P, Kayserili H, Schlack C, Li Y, Brum JM, Barisic I, Castori M, Spaich C, Fletcher E, Mahayri Z, Bhat M, Girisha KM, Lachlan K, Johnson D, Phadke S, Gupta N, Simandlova M, Kabra M, David A, Nijtmans L, Chitayat D, Tuysuz B, Brancati F, Mundlos S, Van Maldergem L, Morava E, Wollnik B, Kornak U (2013). Genotype-phenotype spectrum of PYCR1-related autosomal recessive cutis laxa. Mol Genet Metab. 2013 Nov;110(3):352-61. Doi: 10.1016/j.ymgme.2013.08.009. Epub 2013 Aug 24
  • Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, Anderson R, Hahn A, Innes AM, Suchowersky O, Mets MB, Nürnberg G, McLeod DR, Thiele H, Waggoner D, Altmüller J, Boycott KM, Schoser B, Nürnberg P, Ober C, Heller R, Parboosingh JS, Wollnik B, Sacher M, Lamont RE (2013). Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet. 2013 Jul 11;93(1):181-90. doi: 10.1016/j.ajhg.2013.05.028. Epub 2013 Jul 3
  • Eisenberger T, Neuhaus C, Khan AO, Decker C, Preising MN, Friedburg C, Bieg A, Gliem M, Charbel Issa P, Holz FG, Baig SM, Hellenbroich Y, Galvez A, Platzer K, Wollnik B, Laddach N, Ghaffari SR, Rafati M, Botzenhart E, Tinschert S, Börger D, Bohring A, Schreml J, Körtge-Jung S, Schell-Apacik C, Bakur K, Al-Aama JY, Neuhann T, Herkenrath P, Nürnberg G, Nürnberg P, Davis JS, Gal A, Bergmann C, Lorenz B, Bolz HJ. (2013) Increasing the yield in targeted next-generation sequencing by implicating CNV analysis, non-coding exons and the overall variant load: the example of retinal dystrophies.
    PLoS One. 2013 Nov 12;8(11):e78496. Doi: 10.1371/journal.pone.0078496. ECollection 2013.
  • Kariminejad A, Stollfuß B, Li Y, Bögershausen N, Boss K, Hennekam RC, Wollnik B (2013). Severe Cenani-Lenz syndrome caused by loss of LRP4 function. Am J Med Genet A. Jun;161(6):1475-9. doi: 10.1002/ajmg.a.35920. Epub 2013 May 1
  • Keupp K, Beleggia F, Kayserili H, Barnes AM, Steiner M, Semler O, Fischer B, Yigit G, Janda CY, Becker J, Breer S, Altunoglu U, Grünhagen J, Krawitz P, Hecht J, Schinke T, Makareeva E, Lausch E, Cankaya T, Caparrós-Martín JA, Lapunzina P, Temtamy S, Aglan M, Zabel B, Eysel P, Koerber F, Leikin S, Garcia KC, Netzer C, Schönau E, Ruiz-Perez VL, Mundlos S, Amling M, Kornak U, Marini J, Wollnik B (2013). Mutations in WNT1 cause different forms of bone fragility. Am J Hum Genet. Apr 4;92(4):565-74. doi: 10.1016/j.ajhg.2013.02.010. Epub 2013 Mar 14
  • Reintjes N, Li Y, Becker A, Rohmann E, Schmutzler R, Wollnik B (2013). Activating somatic FGFR2 mutations in breast cancer. PLoS One. ;8(3):e60264. doi: 10.1371/journal.pone.0060264. Epub 2013 Mar 20

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Thomas Wunderlich

  • Ackermann B, Kröber S, Torres-Benito L, Borgmann A, Peters M, Hosseini Barkooie SM, Tejero R, Jakubik M, Schreml J, Milbradt J, Wunderlich FT, Riessland M, Tabares L, Wirth B (2013). Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality. Hum Mol Genet. Apr 1;22(7):1328-47. doi: 10.1093/hmg/dds540. Epub 2012 Dec 20
  • Gruber S, Straub BK, Ackermann PJ, Wunderlich CM, Mauer J, Seeger JM, Büning H, Heukamp L, Kashkar H, Schirmacher P, Brüning JC, Wunderlich FT (2013). Obesity promotes liver carcinogenesis via Mcl-1 stabilization independent of IL-6Rα signaling. Cell Rep. 2013 Aug 29;4(4):669-80. doi: 10.1016/j.celrep.2013.07.023. Epub 2013 Aug 15
  • Pal M, Wunderlich CM, Spohn G, Brönneke HS, Schmidt-Supprian M, Wunderlich FT (2013). Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice. PLoS One. 2013;8(1):e54247. doi: 10.1371/journal.pone.0054247. Epub 2013 Jan 17
  • Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA (2013). Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. 2013 Feb;70(3):527-43. doi: 10.1007/s00018-012-1142-y. Epub 2012 Sep 4
  • Ruud J, Wilhelms DB, Nilsson A, Eskilsson A, Tang YJ, Ströhle P, Caesar R, Schwaninger M, Wunderlich FT, Bäckhed F, Engblom D, Blomqvist A (2013). Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells. FASEB J. May;27(5):1973-80. doi: 10.1096/fj.12-225433. Epub 2013 Feb 8
  • Stöhr O, Schilbach K, Moll L, Hettich MM, Freude S, Wunderlich FT, Ernst M, Zemva J, Brüning JC, Krone W, Udelhoven M, Schubert M (2013). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. Age (Dordr). Feb;35(1):83-101. doi: 10.1007/s11357-011-9333-2. Epub 2011 Nov 6
  • Tovar S, Paeger L, Hess S, Morgan DA, Hausen AC, Brönneke HS, Hampel B, Ackermann PJ, Evers N, Büning H, Wunderlich FT, Rahmouni K, Kloppenburg P, Brüning JC (2013). K(ATP)-channel-dependent regulation of catecholaminergic neurons controls BAT sympathetic nerve activity and energy homeostasis. Cell Metab. 2013 Sep 3;18(3):445-55. doi: 10.1016/j.cmet.2013.08.006
  • Wunderlich CM, Hövelmeyer N, Wunderlich FT (2013). Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity. JAKSTAT. 2013 Apr 1;2(2):e23878. Review

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