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Publications 2012

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Adam Antebi

  • Schaedel ON, Gerisch B, Antebi A, Sternberg PW (2012). Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood. PLoS Biology. 10, e1001306
  • Shen Y, Wollam J, Magner D, Karalay O, Antebi A (2012). A steroid receptor-microRNA switch regulates life span in response to signals from the gonad. Science. 338, 1472-1476
  • Wiese M, Antebi A, Zheng H (2012). Regulation of neuronal APL-1 expression by cholesterol starvation. PloS One. 7, e32038
  • Wollam J, Magner DB, Magomedova L, Rass E, Shen Y, Rottiers V, Habermann B, Cummins CL, Antebi A (2012). A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity. PLoS Biology. 10, e1001305

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Thomas Benzing

  • Benzing T, Schermer B (2012). Clinical spectrum and pathogenesis of nephronophthisis. Curr Opin Nephrol Hypertens. 21: 272–8
  • Borgal L, Habbig S, Hatzold J, Liebau M, Dafinger C, Sacarea I, Hammerschmidt M, Benzing T, Schermer B (2012). The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate ?-catenin signaling. J Biol Chem. 287: 25370–80
  • Brähler S, Ising C, Hagmann H, Rasmus M, Hoehne M, Kurschat C, Kisner T, Goebel H, Shankland S, Addicks K, Thaiss F, Schermer B, Schermer B, Pasparakis M, Benzing T, Brinkkoetter P (2012). Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. Am J Physiol Renal Physiol. 303: F1473-85
  • Brunkwall J, Matoussevitch V, Konner K, Scholer C, Bangard C, Maintz D, Benzing T (2012). Shunt Surgery - Do we need Shunt Centres? Zentralbl Chir. 137: 397–400
  • Chaki M, Airik R, Ghosh A, Giles R, Chen R, Slaats G, Wang H, Hurd T, Zhou W, Cluckey A, Gee H, Ramaswami G, Hong C, Hamilton B, Cervenka I, Ganji R, Bryja V, Arts H, van Reeuwijk J, Oud M, Letteboer S, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer J, Schermer B, Liebau M, Benzing T, Le Corre S, Drummond I, Janssen S, Allen S, Natarajan S, O’Toole J, Attanasio M, Saunier S, Antignac C, Koenekoop R, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson J, Andreoli S, Doherty D, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud E, Al-Rajhi A, Lewis R, Omran H, Lee E, Wang S, Sekiguchi J, Saunders R, Johnson C, Garner E, Vanselow K, Andersen J, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto E, Hildebrandt F (2012). Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell. 150: 533–48
  • Dierkes F, Andriopoulos N, Sucker C, Kuhr K, Hollenbeck M, Hetzel G, Burst V, Teschner S, Rump L, Benzing T, Grabensee B, Kurschat C (2012). Indicators of acute and persistent renal damage in adult thrombotic microangiopathy. PLoS ONE. 7: e30886
  • Er F, Nia A, Dopp H, Hellmich M, Dahlem K, Caglayan E, Kubacki T, Benzing T, Erdmann E, Burst V, Gassanov N: Ischemic preconditioning for prevention of contrast medium-induced nephropathy (2012). randomized pilot RenPro Trial (Renal Protection Trial). Circulation. 126: 296–303
  • Habbig S, Bartram M, Muller R, Benzing T, Schermer B (2012). The nephronophthisis proteins NPHP9 and NPHP4 corporately regulate Hippo-signaling. Eur J Pediatr. 171: 1430–1430
  • Habbig S, Bartram M, Sägmüller J, Griessmann A, Franke M, Müller R, Schwarz R, Hoehne M, Bergmann C, Tessmer C, Reinhardt H, Burst V, Benzing T, Schermer B (2012). The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Hum Mol Genet. 21: 5528–38
  • Hagmann H, Thadhani R, Benzing T, Karumanchi S, Stepan H (2012). The promise of angiogenic markers for the early diagnosis and prediction of preeclampsia. Clin Chem. 58: 837–45
  • Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt H (2012). Putting the brakes on p53-driven apoptosis. Cell Cycle. 11: 4122–8
  • Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos M, Thomas R, Lowery D, Roels F, Fischer M, Liebau M, Resch U, Kisner T, Roether F, Bartram M, Mueller R, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema R, Yaffe M, Schermer B, Reinhardt Hc, Benzing T (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J. 31: 3961–3975
  • Kisner T, Pfister R, Engels M, Benzing T, Michels G (2012). De novo sarcoidosis after kidney transplantation. Dtsch Med Wochenschr. 137: 476–8
  • Kisner T, Burst V, Teschner S, Benzing T, Kurschat C (2012). Rituximab treatment for adults with refractory nephrotic syndrome: a single-center experience and review of the literature. Nephron Clin Pract. 120: c79-85
  • Khurshid S, Kurschat P, Niessen C, Schermer B, Benzing T, Hoepker K (2012). Apoptosis Antagonizing Transcription Factor AATF links DNA damage signaling to epidermal development and the maintenance of skin barrier function. J Invest Dermatol. 132: S104–S104
  • Liebau M, Dafinger C, Elsayed S, Fabretti F, Dosch J, Elsobky E, Benzing T, Bolz H, Schermer B (2012). The novel Joubert Gene KIF7 regulates microtubular dynamics and cellular polarity. Eur J Pediatr. 171: 1427–1427
  • Müller R, Benzing T (2012). A photo shoot of proteinuria: zebrafish models of inducible podocyte damage. J Am Soc Nephrol. 23: 969–71
  • Seeger-Nukpezah T, Liebau M, Höpker K, Lamkemeyer T, Benzing T, Golemis E, Schermer B (2012). The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1. PLoS ONE. 7: e38838
  • Teschner S, Stippel D, Grunenberg R, Beck B, Wahba R, Gathof B, Benzing T, Burst V (2012). ABO-incompatible kidney transplantation using regenerative selective immunoglobulin adsorption. J Clin Apheresis. 27: 51–60
  • Thadhani R, Hemphill L, Kisner T, Hagmann H, Noack S, Benzing T, Bossung V, Mallmann P, Kribs A, Cornely O, Schaarschmidt W, Jank A, Stepan H, Kreyssig C, Lindner T, Rigby A, Khedkar S, Karumanchi S (2012). Response to Letters Regarding Article. Circulation. 125: E523–E524
  • Voelker L, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Hoehne M, Kispert A (2012). Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol. 137: 355–366

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Matteo Bergami

  • Bagozzi RP, Bergami M, Marzocchi GL, Morandin G (2012). Customer-organization relationships: development and test of a theory of extended identities. J Appl Psychol. 2012 Jan;97(1):63-76. doi: 10.1037/a0024533
  • Bergami M, Berninger B (2012). A fight for survival: the challenges faced by a newborn neuron integrating in the adult hippocampus. Dev Neurobiol. 72:1016-1031
  • Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M (2012). A radial glia-specific role of RhoA in double cortex formation. Neuron. 73, 911-924
  • Verderio C, Cagnoli C, Bergami M, Francolini M, Schenk U, Colombo A, Riganti L, Frassoni C, Zuccaro E, Danglot L, Wilhelm C, Galli T, Canossa M, Matteoli M (2012). TI-VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes. Biol Cell. 104, 213-228

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Andreas Beyer

  • Ackermann M, Beyer A (2012). Systematic Detection of Epistatic Interactions Based on Allele Pair Frequencies. PLoS Genetics. 8(2):e1002463
  • Ackermann M, Clément-Ziza M, Michaelson JJ, Beyer A (2012). Teamwork: Improved eQTL Mapping Using Combinations of Machine Learning Methods. PLoS ONE. 7(7): e40916
  • Pancaldi V, Saraç ÖS, Rallis C, McLean JR, Převorovský M, Gould K, Beyer A, Bähler J (2012). Predicting the fission yeast protein interaction network. G3 (Bethesda). 2(4):453-67
  • Saraç ÖS, Pancaldi V, Bähler J, Beyer A (2012). Topology of functional networks predicts physical binding of proteins. Bioinformatics. 28(16):2137

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Susanne Brodesser

  • Schwamb J, Feldhaus V, Baumann M, Patz M, Brodesser S, Brinker R, Claasen J, Pallasch CP, Hallek M, Wendtner CM, Frenzel LP (2012). B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides. Blood. Nov 8;120(19):3978-85. doi: 10.1182/blood-2012-05-431783. Epub 2012 Aug 27
  • Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M (2012). Activating transcription factor 3 regulates immune and metabolic homeostasis. Mol Cell Biol. Oct;32(19):3949-62. doi: 10.1128/MCB.00429-12. Epub 2012 Jul 30
  • von Berlepsch S, Kunz HH, Brodesser S, Fink P, Marin K, Flügge UI, Gierth M (2012). The Acyl-Acyl Carrier Protein Synthetase from Synechocystis sp. PCC 6803 Mediates Fatty Acid Import. Plant Physiol. Jun;159(2):606-17. Epub 2012 Apr 24
  • Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Günschmann C, Sandhoff K, Niessen CM, Niemann C (2012). TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function. J Invest Dermatol. Feb;132(2):337-45. doi: 10.1038/jid.2011.301. Epub 2011 Sep 22

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Jens Brüning

  • Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Brüning JC (2012). Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun. 421(2): 197-202. Epub 2012 Apr 4
  • Blumbach K, Niehoff A, Belgardt BF, Ehlen HW, Schmitz M, Hallinger R, Schulz JN, Brüning JC, Krieg T, Schubert M, Gullberg D, Eckes B (2012). Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. J Biol Chem. 287(9): 6431-40
  • Könner AC, Brüning JC (2012). Selective insulin and leptin resistance in metabolic disorders. Cell Metab. Aug 8;16(2):144-52
  • Kornfeld JW, Brüning JC (2012). MyomiRs-133 turn off the heat. Nat Cell Biol. Dec;14(12):1248-9. doi: 10.1038/ncb2642
  • Marino JS, Iler J, Dowling AR, Chua S, Brüning JC, Coppari R, Hill JW (2012). Adipocyte Dysfunction in a Mouse Model of Polycystic Ovary Syndrome (PCOS): Evidence of Adipocyte Hypertrophy and Tissue-Specific Inflammation. PLoS One. 2012;7(10): e48643. doi: 10.1371/journal.pone.0048643. Epub 2012 Oct 31
  • Newton AJ, Hess S, Paeger L, Vogt MC, Fleming Lascano J, Nillni EA, Brüning JC, Kloppenburg P, Xu AW (2012). AgRP Innervation onto POMC Neurons Increases with Age and Is Accelerated with Chronic High-Fat Feeding in Male Mice. Endocrinology. 154 Jan:172-183
  • Rother E, Belgardt BF, Tsaousidou E, Hampel B, Waisman A, Myers MG Jr, Brüning JC (2012). Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature. Proc Natl Acad Sci U S A. 109(44):18132-7
  • Vogt MC, Brüning JC (2012). CNS insulin signaling in the control of energy homeostasis and glucose metabolism – from embryo to old age. Trends Endocrinol Metab. Dec 18. doi:pii: S1043-2760(12)00204-4. 10.1016/j.tem.2012.11.004. Epub 2012 Dec 19
  • Whitham M, Chan MH, Pal M, Matthews VB, Prelovsek O, Lunke S, El-Osta A, Broenneke H, Alber J, Brüning JC, Wunderlich FT, Lancaster GI, Febbraio MA (2012). Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1. J Biol Chem.  287(14): 10771-9.
  • Wunderlich CM, Delić D, Behnke K, Meryk A, Ströhle P, Chaurasia B, Al-Quraishy S, Wunderlich F, Brüning JC, Wunderlich FT (2012). Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice. J Immunol. 188(9):4141-4. Epub 2012 Mar 30

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Oliver A. Cornely

  • Cornely OA, Miller MA, Louie TJ, Crook DW, Gorbach SL (2012). Treatment of First Recurrence of Clostridium difficile Infection: Fidaxomicin Versus Vancomycin. Clin Infect Dis. Aug;55 Suppl S154-61
  • Cornely OA, Helfgott D, Langston A, Heinz W, Vehreschild JJ, Vehreschild MJ, Krishna G, Ma L, Huyck S, McCarthy MC (2012). Pharmacokinetics of different dosing strategies of oral posaconazole in patients with compromised gastrointestinal function and who are at high risk for invasive fungal infection. Antimicrob Agents Chemother. May;56(5):2652-8
  • Cornely OA, Crook DW, Esposito R, Poirier A, Somero MS, Weiss K, Sears P, Gorbach S, OPT-80-004 Clinical Study Group (2012). Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial. Lancet Infect Dis. Apr;12(4):281-9
  • Cornely OA, Miller MA, Louie TJ, Crook DW, Gorbach SL (2012). Treatment of First Recurrence of Clostridium difficile Infection: Fidaxomicin Versus Vancomycin. Clin Infect Dis. 2012;55 Suppl 2:S154-61
  • Farowski F, Cornely OA, Vehreschild JJ, Bauer T, Hartmann P, Steinbach A, Vehreschild MJ, Scheid C, Müller C (2012). Intracellular concentrations of micafungin in different cellular compartments of the peripheral blood. Int J Antimicrob Agents. Mar; 39(3):228-31
  • Hamprecht A, Buchheidt D, Vehreschild JJ, Cornely OA, Spiess B, Plum G, et al (2012). Azole-resistant invasive aspergillosis in a patient with acute myeloid leukaemia in Germany. Euro Surveill. 2012;17(36):20262
  • Jung N, Kummerle T, Brengelmann SD, Gielen J, Lehmann C, Wyen C, et al (2012). Liver involvement in HIV-infected patients diagnosed with syphilis. Infection. 2012;40(5):543-7
  • Liss BJ, Vehreschild JJ, Cornely OA, Hallek M, Fatkenheuer G, Wisplinghoff H, et al (2012). Intestinal colonisation and blood stream infections due to vancomycin-resistant enterococci (VRE) and extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBLE) in patients with haematological and oncological malignancies. Infection. 2012;40(6):613-9
  • Rieger CT, Cornely OA, Hoppe-Tichy T, Kiehl M, Knoth H, Thalheimer M, et al (2012). Treatment cost of invasive fungal disease (Ifd) in patients with acute myelogenous leukaemia (Aml) or myelodysplastic syndrome (Mds) in German hospitals. Mycoses. 2012;55(6):514-20
  • Vehreschild JJ, Birtel A, Vehreschild MJ, Liss B, Farowski F, Kochanek M, Sieniawski M, Steinbach A, Wahlers K, Fätkenheuer G, Cornely OA (2012). Mucormycosis treated with posaconazole: review of 96 case reports. Crit Rev Microbiol. Aug 24. doi: 10.3109/1040841X.2012.711741. Epub 2012 Aug 24
  • Vehreschild JJ, Moritz G, Vehreschild MJ, Arenz D, Mahne M, Bredenfeld H, Chemnitz J, Klein F, Cremer B, Böll B, Kaul I, Wassmer G, Hallek M, Scheid C, Cornely OA (2012). Efficacy and safety of moxifloxacin as antibacterial prophylaxis for patients receiving autologous haematopoietic stem cell transplantation: a randomised trial. Int J Antimicrob Agents. 39(2):130-4
  • Vehreschild JJ, Muller C, Farowski F, Vehreschild MJ, Cornely OA, Fuhr U, et al (2012). Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome. Eur J Clin Pharmacol. 2012;68(6):987-95
  • Vehreschild JJ, Brockelmann PJ, Bangard C, Verheyen J, Vehreschild MJ, Michels G, et al (2012). Pandemic 2009 influenza A(H1N1) virus infection coinciding with invasive pulmonary aspergillosis in neutropenic patients. Epidemiol Infect. 2012;140(10):1848-52
  • Weissinger F, Auner HW, Bertz H, Buchheidt D, Cornely OA, Egerer G, Heinz W, Karthaus M, Kiehl M, Krüger W, Penack O, Reuter S, Ruhnke M, Sandherr M, Salwender HJ, Ullmann AJ, Waldschmidt DT, Wolf HH (2012). Antimicrobial therapy of febrile complications after high-dose chemotherapy and autologous hematopoietic stem cell transplantation-guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol. Aug;91(8):1161-74
  • Würthwein G, Young C, Lanvers-Kaminsky C, Hempel G, Trame MN, Schwerdtfeger R, Ostermann H, Heinz WJ, Cornely OA, Kolve H, Boos J, Silling G, Groll AH (2012). Population pharmacokinetics of liposomal amphotericin B and caspofungin in allogeneic hematopoietic stem cell recipients. Antimicrob Agents Chemother. 56(1):536-43

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Martin Denzel

  • Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel MS, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS (2012). Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. The Journal of Immunology. 188 (2), 854-863

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Sabine Eming

  • Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Bruning JC (2012). Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun. 421:197-202
  • Nast A, Eming SA, Fluhr J, Fritz K, Gauglitz G, Hohenleutner S, Panizzon RG, Sebastian G, Sporbeck B, Koller J (2012). German S2k guidelines for the therapy of pathological scars. J Dtsch Dermatol Ges. 10(10):747-62
  • Riese A, Eilert Y, Meyer Y, Arin M, Baron JM, Eming SA, Krieg T, Kurschat P (2012). Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis. PLoS One. 7(12):e50944
  • Willenborg S, Lucas T, Geert van Loo, Knipper J, Krieg T, Ingo Haase, Bent Brachvogel, Matthias Hammerschmidt, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012). CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 120:613-625
  • Wood W, Eming SA (2012). Repair or Regenerate – How can we tip the balance? EMBO Report. 13(12):1040-1042

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Lukas P. Frenzel

  • Baer C, Claus R, Frenzel LP, Zucknick M, Park YJ, Gu L, Weichenhan D, Fischer M, Pallasch CP, Herpel E, Rehli M, Byrd JC, Wendtner CM, Plass C (2012). Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia. Cancer Res. Aug 1;72(15):3775-85. Epub 2012 Jun 18
  • Krause G, Patz M, Isaeva P, Wigger M, Baki I, Vondey V, Kerwien S, Kuckertz M, Brinker R, Claasen J, Frenzel LP, Wendtner CM, Heider KH, Hallek M (2012). Action of novel CD37 antibodies on chronic lymphocytic leukemia cells. Leukemia. 2012 Mar;26(3):546-9. doi: 10.1038/leu.2011.233. No abstract available
  • Kuckertz M, Patz M, Veldurthy A, Gehrke I, Claasen J, Frenzel LP, Wendtner CM, Hallek M, Krause G (2012). Comparison of the effects of two kinase inhibitors, sorafenib and dasatinib, on chronic lymphocytic leukemia cells. Onkologie. ;35(7-8):420-6. doi: 10.1159/000341081. Epub 2012 Jul 6
  • Schwamb J, Feldhaus V, Baumann M, Patz M, Brodesser S, Brinker R, Claasen J, Pallasch CP, Hallek M, Wendtner CM, Frenzel LP (2012). B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides. Blood. Nov 8;120(19):3978-85. doi: 10.1182/blood-2012-05-431783. Epub 2012 Aug 27

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Peter Frommolt

  • Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Thiele H, Edwards A, Arends MJ, Miró X, White JK, Désir J, Abramowicz M, Dentici ML, Lepri F, Hofmann K, Har-Zahav A, Ryder E, Karp NA, Estabel J, Gerdin AK, Podrini C, Ingham NJ, Altmüller J, Nürnberg G, Frommolt P, Abdelhak S, Pasmanik-Chor M, Konen O, Kelley RI, Shohat M, Nürnberg P, Flint J, Steel KP, Hoppe T, Kubisch C, Adams DJ, Borck G (2012). Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. Dec 7;91(6):998-1010. doi: 10.1016/j.ajhg.2012.10.011. Epub 2012 Nov 29
  • Borck G, Shin BS, Stiller B, Mimouni-Bloch A, Thiele H, Kim JR, Thakur M, Skinner C, Aschenbach L, Smirin-Yosef P, Har-Zahav A, Nürnberg G, Altmüller J, Frommolt P, Hofmann K, Konen O, Nürnberg P, Munnich A, Schwartz CE, Gothelf D, Colleaux L, Dever TE, Kubisch C, Basel-Vanagaite L (2012). eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation. Mol Cell. Nov 30;48(4):641-6. doi: 10.1016/j.molcel.2012.09.005. Epub 2012 Oct 11
  • Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M (2012). Activating transcription factor 3 regulates immune and metabolic homeostasis. Mol Cell Biol. Oct;32(19):3949-62. doi: 10.1128/MCB.00429-12. Epub 2012 Jul 30
  • Rosewich H, Thiele H, Ohlenbusch A, Maschke U, Altmüller J, Frommolt P, Zirn B, Ebinger F, Siemes H, Nürnberg P, Brockmann K, Gärtner J (2012). Heterozygous de-novo mutations in ATP1A3 in patients with alternating hemiplegia of childhood: a whole-exome sequencing gene-identification study.
    Lancet Neurol.
    Sep;11(9):764-73. doi: 10.1016/S1474-4422(12)70182-5. Epub 2012 Jul 30
  • Meimaridou E, Kowalczyk J, Guasti L, Hughes CR, Wagner F, Frommolt P, Nürnberg P, Mann NP, Banerjee R, Saka HN, Chapple JP, King PJ, Clark AJ, Metherell LA (2012). Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency. Nat Genet. May 27;44(7):740-2. doi: 10.1038/ng.2299
  • Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P (2012). A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. May 4;90(5):871-8. Epub 2012 Apr 19
  • Asharani PV, Keupp K, Semler O, Wang W, Li Y, Thiele H, Yigit G, Pohl E, Becker J, Frommolt P, Sonntag C, Altmüller J, Zimmermann K, Greenspan DS, Akarsu NA, Netzer C, Schönau E, Wirth R, Hammerschmidt M, Nürnberg P, Wollnik B, Carney TJ (2012). Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet. Apr 6;90(4):661-74
  • Frommolt P, Abdallah AT, Altmüller J, Motameny S, Thiele H, Becker C, Stemshorn K, Fischer M, Freilinger T, Nürnberg P (2012). Assessing the enrichment performance in targeted resequencing experiments. Hum Mutat. Apr;33(4):635-41. doi: 10.1002/humu.22036. Epub 2012 Feb 28
  • Weber S, Thiele H, Mir S, Toliat MR, Sozeri B, Reutter H, Draaken M, Ludwig M, Altmüller J, Frommolt P, Stuart HM, Ranjzad P, Hanley NA, Jennings R, Newman WG, Wilcox DT, Thiel U, Schlingmann KP, Beetz R, Hoyer PF, Konrad M, Schaefer F, Nürnberg P, Woolf AS (2011). Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome. Am J Hum Genet. Nov 11;89(5):668-74

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Michael Hallek

  • Bauer K, Rancea M, Roloff V, Elter T, Hallek M, Engert A, Skoetz N (2012). Rituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia. Cochrane Database Syst Rev. Nov 14;11:CD008079. doi:10.1002/14651858.CD008079.pub2
  • Böttcher S, Ritgen M, Fischer K, Stilgenbauer S, Busch RM, Fingerle-Rowson G, Fink AM, Bühler A, Zenz T, Wenger MK, Mendila M, Wendtner CM, Eichhorst BF, Döhner H, Hallek M, Kneba M (2012). Minimal residual disease quantification is an independent predictor of progression-free and overall survival in chronic lymphocytic leukemia: a multivariate analysis from the randomized GCLLSG CLL8 trial. J Clin Oncol.  2012 Mar 20;30(9):980-8. Epub 2012 Feb 13
  • Chemnitz JM, von Lilienfeld-Toal M, Holtick U, Theurich S, Shimabukuro-Vornhagen A, Krause A, Brossart P, Hallek M, Scheid C (2012). Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia. Ann Hematol. 2012 Jan;91(1):47-55. Epub 2011 May 17
  • Cramer P, Hallek M (2012). Hematological cancer in 20New therapeutic targets and treatment strategies. Nat Rev Clin Oncol. 2012 Jan 10;9(2):72-4. doi: 10.1038/nrclinonc.2011.212. Review
  • Dreger P, Döhner H, McClanahan F, Busch R, Ritgen M, Greinix H, Fink AM, Knauf W, Stadler M, Pfreundschuh M, Dührsen U, Brittinger G, Hensel M, Schetelig J, Winkler D, Bühler A, Kneba M, Schmitz N, Hallek M, Stilgenbauer S (2012). On behalf of the German CLL Study Group. Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial. Blood. 2012 May 24;119(21):4851-4859. Epub 2012 Apr 5
  • Edelmann J, Holzmann K, Miller F, Winkler D, Bühler A, Zenz T, Bullinger L, Kühn MW, Gerhardinger A, Bloehdorn J, Radtke I, Su X, Ma J, Pounds S, Hallek M, Lichter P, Korbel J, Busch R, Mertens D, Downing JR, Stilgenbauer S, Döhner H (2012). High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations. Blood. Dec 6;120(24):4783-94. doi: 10.1182/blood-2012-04-423517. Epub 2012 Oct 9
  • Engert A, Haverkamp H, Kobe C, Markova J, Renner C, Ho A, Zijlstra J, Král Z, Fuchs M, Hallek M, Kanz L, Döhner H, Dörken B, Engel N, Topp M, Klutmann S, Amthauer H, Bockisch A, Kluge R, Kratochwil C, Schober O, Greil R, Andreesen R, Kneba M, Pfreundschuh M, Stein H, Eich HT, Müller RP, Dietlein M, Borchmann P, Diehl V; German Hodgkin Study Group; Swiss Group for Clinical Cancer Research; Arbeitsgemeinschaft Medikamentöse Tumortherapie (2012). Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial. Lancet. 2012 May 12;379(9828):1791-9. Epub 2012 Apr 4. Erratum in: Lancet. 2012 May 12;379(9828):1790
  • Fischer K, Cramer P, Busch R, Böttcher S, Bahlo J, Schubert J, Pflüger KH, Schott S, Goede V, Isfort S, von Tresckow J, Fink AM, Bühler A, Winkler D, Kreuzer KA, Staib P, Ritgen M, Kneba M, Döhner H, Eichhorst BF, Hallek M, Stilgenbauer S, Wendtner CM (2012). Bendamustine in combination with rituximab for previously untreated patients with chronic lymphocytic leukemia: a multicenter phase II trial of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol. Sep 10;30(26):3209-16. doi: 10.1200/JCO.2011.39.2688. Epub 2012 Aug 6
  • Gaertner J, Wolf J, Frechen S, Klein U, Scheicht D, Hellmich M, Toepelt K, Glossmann JP, Ostgathe C, Hallek M, Voltz R(2012). Recommending early integration of palliative care - does it work? Support Care Cancer. 2012 Mar;20(3):507-13. Epub 2011 Feb 19
  • Hallek M (2012). FCA: Forget Chemoimmunotherapy with Alemtuzumab? Blood. 2012 May 31;119(22):5059-60
  • Hösel M, Broxtermann M, Janicki H, Esser K, Arzberger S, Hartmann P, Gillen S, Kleeff J, Stabenow D, Odenthal M, Knolle P, Hallek M, Protzer U, Büning H (2012). Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors. Hepatology. 2012 Jan;55(1):287-97. doi: 10.1002/hep.24625
  • Koehler P, Schmidt P, Hombach AA, Hallek M, Abken H. (2012). Engineered T cells for the adoptive therapy of B-cell chronic lymphocytic leukaemia. Adv Hematol. 2012;2012:595060. Epub 2011 Aug 8
  • Köppler H, Fuss H, Hurtz HJ, Knigge O, Losem C, Reschke D, Schmitz S, Weide R, Weiß J, Hallek M (2012). For the GCLLSG. Bendamustine plus mitoxantrone for relapsed/refractory chronic lymphocytic leukaemia (CLL): results of a multicentre phase II study of the German CLL Study Group (GCLLSG). Br J Haematol. 2012 Jul;158(2):238-241. doi: 10.1111/j.1365-2141.2012.09132.x. Epub 2012 May 10
  • Marmé D, Hallek M (2012). Personalized cancer medicine. Onkologie. 2012;35 Suppl 1:2. Epub 2012 Jan 20
  • Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK (2012). Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. Oct;44(10):1104-10. doi: 10.1038/ng.2396. Epub 2012 Sep 2
  • Schwamb J, Feldhaus V, Baumann M, Patz M, Brodesser S, Brinker R, Claasen J, Pallasch CP, Hallek M, Wendtner CM, Frenzel LP (2012). B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides. Blood. Nov 8;120(19):3978-85. doi: 10.1182/blood-2012-05-431783. Epub 2012 Aug 27
  • Schweighofer CD, Tuchscherer A, Sperka S, Meyer T, Rattel B, Stein S, Ismail S, Elter T, Staib P, Reiser M, Hallek M (2012). Clinical safety and pharmacological profile of the HLA-DR antibody 1D09C3 in patients with B cell chronic lymphocytic leukemia and lymphoma: results from a phase I study. Cancer Immunol Immunother. Dec;61(12):2367-73. doi: 10.1007/s00262-012-1362-x. Epub 2012 Oct 23
  • Skoetz N, Bauer K, Elter T, Monsef I, Roloff V, Hallek M, Engert A (2012). Alemtuzumab for patients with chronic lymphocytic leukaemia. Cochrane Database Syst Rev. 2012 Feb 15;2:CD008078. Review
  • Vehreschild JJ, Moritz G, Vehreschild MJ, Arenz D, Mahne M, Bredenfeld H, Chemnitz J, Klein F, Cremer B, Böll B, Kaul I, Wassmer G, Hallek M, Scheid C, Cornely OA (2012). Efficacy and safety of moxifloxacin as antibacterial prophylaxis for patients receiving autologous haematopoietic stem cell transplantation: a randomised trial. Int J Antimicrob Agents. 2012 Feb;39(2):130-4. Epub 2011 Dec 12
  • Wendtner CM, Hillmen P, Mahadevan D, Bühler A, Uharek L, Coutré S, Frankfurt O, Bloor A, Bosch F, Furman RR, Kimby E, Gribben JG, Gobbi M, Dreisbach L, Hurd DD, Sekeres MA, Ferrajoli A, Shah S, Zhang J, Moutouh-de Parseval L, Hallek M, Heerema NA, Stilgenbauer S, Chanan-Khan AA (2012). Final results of a multicenter phase 1 study of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia. Leuk Lymphoma. 2012 Mar;53(3):417-23. Epub 2011 Nov 15
  • Zenz T, Gribben JG, Hallek M, Döhner H, Keating MJ, Stilgenbauer S. (2012). Risk categories and refractory CLL in the era of chemoimmunotherapy. Blood. 2012 May 3;119(18):4101-7. Epub 2012 Mar 6

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Matthias Hammerschmidt

  • Ameln von S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C (2012). A mutation in PNPT1, encoding mitochondrial–RNA-import protein PNPase, causes hereditary hearing loss. Am J Human Genet. 91, 919-927
  • Asharani PV, Keupp K, Semler O, Wang W, Li Y, Thiele H, Yigit G, Pohl E, Becker J, Frommolt P, Sonntag C, Altmüller J, Zimmermann K, Greenspan DS, Akarsu NA, Netzer C, Schönau E, Wirth R, Hammerschmidt M, Nürnberg P, Wollnik B, Carney TJ (2012). Attenuated. BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet. 90, 661-674
  • Borgal L, Habbig S, Hatzold J, Liebau MC, Sacarea I, Hammerschmidt M, Benzing T, Schermer B (2012). The ciliary protein Nephrocystin-4 translocates the canonical Wnt-regulator Jade-1 to the nucleus to negatively regulate beta-Catenin signaling. J Biol Chem. 287, 25370-25380
  • Feitosa NM, Zhang J, Carney TJ, Metzger M, Korzh V, Bloch W, Hammerschmidt M (2012). Hemicentin2 and Fibulin1 are required for epidermal-dermal junction formation and fin mesenchymal cell migration during zebrafish development. Dev Biol. 369, 235-248
  • Naye F, Voz ML, Detry N, Hammerschmidt M, Peers B, Manfroid I (2012). Essential roles of zebrafish bmp2a, fgf10 and fgf24 in the specification of the ventral pancreas. Mol Biol Cell. 23, 945-954
  • Pater de E, Ciampricotti M, Priller F, Veerkamp J, State I, Smith K, Lagendijk AK, Schilling T, Herzog W, Abdelilah-Seyfried S, Hammerschmidt M, Bakkers J (2012). Bmp signalling exerts opposite effects on cardiac differentiation. Circ Res. 110, 578-587
  • Quiroz Y, Lopez M, Mavropoulos A, Motte P, Martial JA, Hammerschmidt M, Muller M (2012). The HMG-box transcription factor Sox4b is required for pituitary expression of gata2 and specification of the thyrotrope and gonadotrope cells in zebrafish. Mol Endocrinol. 26, 1014-1027
  • Talbot JC, Walker MB, Carney TC, Huycke TR, Yan YL, Bremiller RA, Gai L, DeLaurier A, Postlethwait JH, Hammerschmidt M, Kimmel CB (2012). Fras1 shapes endodermal pouch 1 and stabilizes zebrafish pharyngeal skeletal development. Development. 139, 2804-2813
  • Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012). CCR2 recurits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 120, 613-625

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Hans Christian Hennies

  • Aufenvenne K, Rice RH, Hausser I, Oji V, Hennies HC, Rio MD, Traupe H, Larcher F (2012). Long-term faithful recapitulation of transglutaminase 1-deficient lamellar ichthyosis in a skin-humanized mouse model, and insights from proteomic studies. J Invest Dermatol. Jul;132(7):1918-21
  • Blaydon DC, Etheridge SL, Risk JM, Hennies HC, Gay LJ, Carroll R, Plagnol V, McRonald FE, Stevens HP, Spurr NK, Bishop DT, Ellis A, Jankowski J, Field JK, Leigh IM, South AP, Kelsell DP (2012). RHBDF2 mutations are associated with tylosis, a familial oesophageal cancer syndrome. Am J Hum Genet. Feb 10;90(2):340-6
  • Dolmans GH, Hennies HC, The genetic basis of Dupuytren’s disease. An introduction. In: Eaton C et al (eds.), Morbus Dupuytren and related hyperproliferative disorders. Springer Heidelberg. pp 87-93 (2012)
  • Forstbauer LM, Brockschmidt FF, Moskvina V, Herold C, Redler S, Herzog A, Hillmer AM, Meesters C, Heilmann S, Albert F, Alblas M, Hanneken S, Eigelshoven S, Giehl KA, Jagielska D, Blume-Peytavi U, Garcia Bartels N, Kuhn J, Hennies HC, Goebeler M, Jung A, Peitsch WK, Kortüm AK, Moll I, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Kirov G, Becker T, Nöthen MM, Betz RC (2012). Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata. Eur J Hum Genet. Mar;20(3):326-32
  • Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P (2012). A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. May 4;90(5):871-8
  • Jansen PA, van den Bogaard EH, Kersten FF, Oostendorp C, van Vlijmen-Willems IM, Oji V, Traupe H, Hennies HC, Schalkwijk J, Zeeuwen PL (2012). Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis of human skin equivalents. Exp Dermatol. Nov;21(11):889-91

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Marco Herling

  • Böll B, Dickerhoff R, Herling M, Klein F (2012). Blut und blutbildende Organe. In: Renz-Polster und Krautzig eds., Basislehrbuch Innere Medizin. (chapter 3, pp. 248-324, in German), 5th edition 2012, Elsevier / Urban & Fischer (ISBN: 978-3437411144)
  • Brechmann M, Mock T, Nickles D, Kiessling M, Weit N, Breuer R, Müller W, Wabnitz G, Frey F, Nicolay JP, Booken N, Samstag Y, Klemke CD, Herling M, Boutros M, Krammer PH, Arnold R (2012). A PP4 holoenzyme balances physiological and oncogenic nuclear factor-kappa B signaling in T lymphocytes. Immunity. 2012 Oct 19;37(4):697-708
  • Sivina M, Hartmann E, Vasyutina E, Boucas JM, Breuer A, Keating MJ, Wierda WG, Rosenwald A, Herling M, Burger JA (2012). Stromal cells modulate TCL1 expression, interacting AP-1 components, and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia. Leukemia. 2012 Aug;26(8):1812-20

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Thorsten Hoppe

  • Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Hoppe T, Kubisch C, Adams DJ, Borck G (2012). Deficiency for the ubiquitin ligase UBE3B in an intellectual disability syndrome. Am J Hum Genet. 91, 998-1010
  • Dantuma NP, Hoppe T (2012). Growing Sphere of Influence: Cdc48/p97 Orchestrates Ubiquitin-Dependent Extraction from Chromatin. Trends Cell Biol. 22, 483-91
  • Segref A, Hoppe T (2012). Analysis of ubiquitin-dependent proteolysis in C. elegans. Methods Mol Biol. 832, 531-44

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Sandra Iden

  • Ellenbroek SIJ, Iden S, Collard JG (2012). The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network. Small GTPases. Jan 1;3(1):4-14
  • Ellenbroek SIJ, Iden S, Collard JG (2012). Cell polarity proteins and cancer. Semin Cancer Biol. Jun;22(3):208-15
  • Iden S, Misselwitz S, Peddibhotla S, Tuncay H, Rehder D, Gerke V, Robenek H, Suzuki A, Ebnet K (2012). Atypical PKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation. J Cell Biol. 5, 623-39
  • Iden S, van Riel WE, Schäfer R, Song JY, Hirose T, Ohno S, Collard JG (2012). Tumor Type-Dependent Function of the Par3 Polarity Protein in Skin. Tumorigenesis. Cancer Cell, Sep, 22(3):389-403
  • Niessen MT, Iden S, Niesen CM (2012). The in vivo function of mammalian cell and tissue polarity regulators - how to shape and maintain the epidermal barrier. Journal of Cell Science. 2012 Aug
  • Semler O, Garbes L, Keupp K, Swan D, Zimmermann K, Becker J, Iden S, Wirth B, Eysel P, Koerber F, Schoenau E, Bohlander SK, Wollnik B,and Netzer C (2012). A Mutation in the 5´-Untranslated Region of IFITM5 Creates an In-Frame Start Codon and Causes Autosomal-Dominant Osteogenesis Imperfecta with Hyperplastic Callus (OI Type V). Am J Hum Genet. Aug 1

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Hamid Kashkar

  • Böcke A, Sieger D, Kashkar H, Krönke M (2012). FAN mediates navigational capacity of macrophages responding to wounds and infection- live imaging studies in zebrafish larvae. J Immunol. 2012, 189:1559-66
  • Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Niesswandt B, van Rooijen N, Limmer A, Cederbrand K, Heikenwälder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA (2012). TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation. Cell Rep. 2(3):478-487

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Peter Kloppenburg

  • Almajan ER, Richter R, Paeger L, Martinelli P, Barth E, Decker T, Larsson NG, Kloppenburg P, Langer T, Rugarli EI (2012). AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival. J Clin Invest. 2012 Nov;122(11):4048-58. doi: 10.1172/JCI64604
  • Neupert S, Fusca D, Schachtner J, Kloppenburg P, Predel R (2012). Toward a single-cell-based analysis of neuropeptide expression in Periplaneta americana antennal lobe neurons. J Comp Neurol. 2012 Mar 1;520(4):694-716. doi: 10.1002/cne.22745
  • Oliveira EE, Schleicher S, Büschges A, Schmidt J, Kloppenburg P, Salgado VL (2012). Desensitization of nicotinic acetylcholine receptors in central nervous system neurons of the stick insect (Carausius morosus) by imidacloprid and sulfoximine insecticides. Insect Biochem Mol Biol. 2011 Nov;41(11):872-80. doi: 10.1016/j.ibmb.2011.08.001

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Natalia Kononenko

  • Kononenko NL, Witter MP (2012). Presubiculum layer III conveys retrosplenial input to the medial entorhinal cortex. Hippocampus. 22, 881-895
  • Kononenko NL, Kiss T, Elekes K (2012). The neuroanatomical and ultrastructural organization of statocyst hair cells in the pond snail, Lymnaea stagnalis. Acta Biologica Hungarica. 63, 99-113, doi:10.1556/ABiol.63.2012.Suppl.1.10

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Jan-Wilhelm Kornfeld

  • Friedbichler K, Themanns M, Mueller KM, Schlederer M, Kornfeld JW, Terracciano LM, Kozlov AV, Haindl S, Kenner L, Kolbe T, Mueller M, Snibson KJ, Heim MH, Morgige R (2012). Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer. Hepatology. 2012 Mar;55(3):941-52. doi: 10.1002/hep.24765. Epub 2012 Jan 13
  • Kornfeld JW and Brüning JC (2012). Myomirs-133a/b turn off the heat. Nat Cell Biol. 2012 Dec;14(12):1248-9. doi: 10.1038/ncb2642
  • Mueller KM, Themanns M, Friedbichler K, Kornfeld JW, Esterbauer H, Tuckermann JP, Morgige R (2012). Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development. Mol Cell Endocrinol. 2012 Sep 25;361(1-2):1-11. doi: 10.1016/j.mce.2012.03.026. Epub 2012 Apr 30

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Thomas Krieg

  • Abety AN, Fox JW, Schönefuss A, Zamek J, Landsberg J, Krieg T, Blobel C, Mauch C, Zigrino P (2012). Stromal fibroblast-specific expression of ADAM-9 modulates proliferation and apoptosis in melanoma cells in vitro and in vivo. J Invest Dermatol. Oct;132(10):2451-8. doi: 10.1038/jid.2012.153. Epub 2012 May 24
  • Abety AN, Fox JW, Schönefuß A, Zamek J, Landsberg J, Krieg T, Blobel C, Mauch C, Zigrino P (2012). Stromal Fibroblast-Specific Expression of ADAM-9 Modulates Proliferation and Apoptosis in Melanoma Cells In Vitro and In Vivo. J Invest Dermatol. May 24. doi: 10.1038/jid.2012.153. Epub 2012 May 24
  • Agarwal P, Zwolanek D, Keene DR, Schulz JN, Blumbach K, Heinegård D, Zaucke F, Paulsson M, Krieg T, Koch M, Eckes B (2012). Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure. J Biol Chem. Jun 29;287(27):22549-59. Epub 2012 May 9
  • Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Bruning JC (2012). Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun. May 4;421(2):197-202. Epub 2012 Apr 4
  • Behrendt K, Klatte J, Pofahl R, Bloch W, Smyth N, Tscharntke M, Krieg T, Paus R, Niessen C, Niemann C, Brakebusch C, Haase I (2012). A function for Rac1 in the terminal differentiation and pigmentation of hair. J Cell Sci. Feb 15;125(Pt 4):896-905. Epub 2012 Jan 24
  • Blumbach K, Niehoff A, Belgardt BF, Ehlen HW, Schmitz M, Hallinger R, Schulz JN, Brüning JC, Krieg T, Schubert M, Gullberg D, Eckes B (2012). Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. J Biol Chem. Feb 24;287(9):6431-40. Epub 2011 Dec 30
  • Denton CP, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Silkey M, Zultak M, Matucci-Cerinic M; DUO Registry investigators (2012). Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry. Ann Rheum Dis. May;71(5):718-21. Epub 2012 Jan 12
  • Gardizi M, Kurschat C, Riese A, Hahn M, Krieg T, Mauch C, Kurschat P (2012). A decreased ratio between serum levels of the antagonistic angiopoietins 1 and 2 indicates tumour progression of malignant melanoma. Arch Dermatol Res. Jul;304(5):397-400. Epub Mar 13
  • Hunzelmann N, Krieg T, Kooperationspartner der DNSS (2012). The German network for systemic sclerosis (DNSS): current data on diagnostics and therapy. Hautarzt. 63 Suppl1 , 71-75
  • Meier FM, Frommer KW, Dinser R, Walker UA, Czirjak L, Denton CP, Allanore Y, Distler O, Riemekasten G, Valentini G, Müller-Ladner U, EUSTAR Co-authors (2012). Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database. Ann Rheum Dis. Aug;71(8):1355-60. doi: 10.1136/annrheumdis-2011-200742. Epub 2012 May 21
  • Moinzadeh P, Denton CP, Abraham D, Ong V, Hunzelmann N, Eckes B, Krieg T (2012). Biomarkers for skin involvement and fibrotic activity in scleroderma. J Eur Acad Dermatol Venereol. 26, 267-276
  • Neuhaus B, Niessen CM, Mesaros A, Withers DJ, Krieg T, Partridge L (2012). Experimental analysis of risk factors for ulcerative dermatitis in mice. Exp Dermatol. Sep;21(9):712-3. doi: 10.1111/j.1600-0625.2012.01558.x
  • Peters AS, Brunner G, Blumbach K, Abraham DJ, Krieg T, Eckes B (2012). Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFβ1 in dermal fibroblasts. Exp Dermatol. Oct;21(10):765-70. doi: 10.1111/exd.12010
  • Riese A, Eilert Y, Meyer Y, Arin M, Baron JM, Eming S, Krieg T, Kurschat P (2012). Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis. PLoS One. 7, e50944
  • Teruel M, Simeon CP, Broen J, Vonk MC, Carreira P, Camps MT, Garcia-Portales R, Delgado-Frias E, Gallego M, Espinosa G, Ssg TS, Beretta L, Airo P, Lunardi C, Riemekasten G, Witte T, Krieg T, Kreuter A, Distler JH, Hunzelmann N, Koeleman BP, Voskuyl AE, Schuerwegh AJ, Gonzalez-Gay MA, Radstake TR, Martin J (2012). Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis. Arthritis Res Ther. Jun 25;14(3):R154
  • Walker KM, Pope J, participating members of the Scleroderma Clinical Trials Consortium (SCTC), Canadian Scleroderma Research Group (CSRG) (2012). Treatment of systemic sclerosis complications: what to use when first-line treatment fails--a consensus of systemic sclerosis experts. Semin Arthritis Rheum. Aug;42(1):42-55. doi: 10.1016/j.semarthrit.2012.01.003. Epub 2012 Mar 29
  • Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012). CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. Jul 19;120(3):613-25. doi: 10.1182/blood-2012-01-403386. Epub 2012 May 10
  • Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012). CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. May 10. Epub 2012 May 10
  • Xin W, Yang X, Rich TC, Krieg T, Barrington R, Cohen MV, Downey JM (2012). All preconditioning-related G protein-coupled receptors can be demonstrated in the rabbit cardiomyocyte. J Cardiovasc Pharmacol Ther. Jun;17 (2):190-8. Epub 2011 Aug 9
  • Zhang Y, Tocchetti CG, Krieg T, Moens AL (2012). Oxidative and nitrosative stress in the maintenance of myocardial function. Free Radic Biol Med. Oct 15;53(8):1531-40. doi: 10.1016/j.freeradbiomed.2012.07.010. Epub 2012 Jul 20. Review

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Martin Krönke

  • Boecke A, Sieger D, Neacsu CD, Kashkar H, Krönke M (2012). Factor associated with neutral sphingomyelinase activity mediates navigational capacity of leukocytes responding to wounds and infection: live imaging studies in zebrafish larvae. J Immunol. 189: 1559-66
  • Krause KH, Lambeth D, Krönke M (2012). NOX enzymes as drug targets. Cell Mol Life Sci. 69: 2279-82
  • Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA (2012). TNF-induced target cell killing by CTL activated through cross-presentation. Cell Rep. 2: 478-87

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Marcus Krüger

  • Azimifar B, Ralph T. Böttcher, Sara Zanivan, Carsten Grashoff, Krüger M, Kyle R. Legate, Matthias Mann, Reinhard Fässler (2012). The induction of membrane circular dorsal ruffles requires integrin/ILK and EGF receptor co-signalling. Journal of Cell Sci. 125(Pt 2):435-48
  • Bhuwania R, Cornfine S, Fang Z, Krüger M, Luna E, Linder S (2012). Supervillin couples myosin-dependent contractility to podosomes and enables their turnover. Journal of Cell Sci. 125(Pt 2):435-48
  • Cervero P, Himmel M, Krüger M, Linder S (2012). Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres. Eur J Cell Biol. Jun 19. 91(11-12):908-22
  • De la Vega L, Grishina I, Moreno R, Krüger M, Braun T, Schmitz L (2012). A redox-regulated SUMO/acetylation switch of HIPK2 controls the survival threshold to oxidative stress. Mol Cell. May 25;46(4):472-83
  • Drexler HA, Ruhs A, Konzer A, Mendler L, Brookskotten M, Looso M, Günther S, Boettger T, Krüger M, Braun T (2012). On marathons and sprints: an integrated quantitative proteomics and transcriptomics analysis of differences between slow and fast muscle fibers. Mol Cell Proteomics. 2012 Jun;11(6):M111.010801
  • Kanse S, Gallenmueller A, Zeerleder S, Stephan F, Rannou O, Etscheid M, Lochnit G, Krüger M, Huber-Lang M (2012). Factor seven activating protease (FSAP) is activated in multiple trauma patients and generates anaphylatoxin C5a. J. Immunolgy. 188(6):2858-65
  • Looso M, Michel CS, Konzer A, Bruckskotten M, Borchardt T, Krüger M, Braun T (2012). Spiked-in pulsed in vivo labeling identifies a new member of the CCN family in regenerating newt hearts. J Proteome Res.  Sep 7; 11(9):4693-704
  • Maier HJ, Schips TG, Wietelmann A, Krüger M, Brunner C, Sauter M, Klingel K, Böttger T, Braun T, Wirth T (2012). Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. Jul 17; 109(29):11794-9 
  • Saul VV, de la Vega L, Milanovic M, Krüger M, Braun T, Fritz-Wolf K, Becker K, Schmitz ML (2012). HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. J Mol Cell Biol. Sep 20. doi: 10.1093/jmcb/mjs053

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Christian Kubisch

  • Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Thiele H, Edwards A, Arends MJ, Miró X, White JK, Désir J, Abramowicz M, Dentici ML, Lepri F, Hofmann K, Har-Zahav A, Ryder E, Karp NA, Estabel J, Gerdin AK, Podrini C, Ingham NJ, Altmüller J, Nürnberg G, Frommolt P, Abdelhak S, Pasmanik-Chor M, Konen O, Kelley RI, Shohat M, Nürnberg P, Flint J, Steel KP, Hoppe T, Kubisch C, Adams DJ, Borck G (2012). Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. Dec 7;91(6):998-1010. doi: 10.1016/j.ajhg.2012.10.011. Epub 2012 Nov 29
  • Borck G, Kakar N, Hoch J, Friedrich K, Freudenberg J, Nürnberg G, Yilmaz R, Daud S, Baloch DM, Nürnberg P, Oldenburg J, Ahmad J, Kubisch C (2012). An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group. Hum Genet. Feb;131(2):209-16. doi: 10.1007/s00439-011-1062-1. Epub 2011 Jul 15
  • Borck G, Shin BS, Stiller B, Mimouni-Bloch A, Thiele H, Kim JR, Thakur M, Skinner C, Aschenbach L, Smirin-Yosef P, Har-Zahav A, Nürnberg G, Altmüller J, Frommolt P, Hofmann K, Konen O, Nürnberg P, Munnich A, Schwartz CE, Gothelf D, Colleaux L, Dever TE, Kubisch C, Basel-Vanagaite L. (2012) eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation. Mol Cell. Nov 30;48(4):641-6. doi: 10.1016/j.molcel.2012.09.005. Epub 2012 Oct 11
  • Freilinger T, Anttila V, de Vries B, Malik R, Kallela M, Terwindt GM, Pozo-Rosich P, Winsvold B, Nyholt DR, van Oosterhout WP, Artto V, Todt U, Hämäläinen E, Fernández-Morales J, Louter MA, Kaunisto MA, Schoenen J, Raitakari O, Lehtimäki T, Vila-Pueyo M, Göbel H, Wichmann E, Sintas C, Uitterlinden AG, Hofman A, Rivadeneira F, Heinze A, Tronvik E, van Duijn CM, Kaprio J, Cormand B, Wessman M, Frants RR, Meitinger T, Müller-Myhsok B, Zwart JA, Färkkilä M, Macaya A, Ferrari MD, Kubisch C, Palotie A, Dichgans M, van den Maagdenberg AM; International Headache Genetics Consortium (2012). Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nat Genet. Jun 10;44(7):777-82. doi: 10.1038/ng.2307
  • Hisama FM, Kubisch C, Martin GM, Oshima J (2012). Clinical utility gene card for: Werner syndrome. Eur J Hum Genet. May;20(5). doi: 10.1038/ejhg.2011.265. Epub 2012 Jan 18
  • Kakar N, Goebel I, Daud S, Nürnberg G, Agha N, Ahmad A, Nürnberg P, Kubisch C, Ahmad J, Borck G (2012). A homozygous splice site mutation in TRAPPC9 causes intellectual disability and microcephaly. Eur J Med Genet. Dec;55(12):727-31. doi: 10.1016/j.ejmg.2012.08.010. Epub 2012 Aug 30
  • Knoch J, Kamenisch Y, Kubisch C, Berneburg M (2012). Rare hereditary diseases with defects in DNA-repair. Eur J Dermatol. Jul-Aug;22(4):443-55. doi: 10.1684/ejd.2012.1654. Review
  • Lessel D, Gamulin M, Kulis T, Toliat MR, Grgic M, Friedrich K, Zunec R, Balija M, Nürnberg P, Kastelan Z, Högel J, Kubisch C (2012). Replication of genetic susceptibility loci for testicular germ cell cancer in the Croatian population. Carcinogenesis. Aug;33(8):1548-52. doi: 10.1093/carcin/bgs218. Epub 2012 Jun 27
  • Lill CM, Liu T, Schjeide BM, Roehr JT, Akkad DA, Damotte V, Alcina A, Ortiz MA, Arroyo R, Lopez de Lapuente A, Blaschke P, Winkelmann A, Gerdes LA, Luessi F, Fernadez O, Izquierdo G, Antigüedad A, Hoffjan S, Cournu-Rebeix I, Gromöller S, Faber H, Liebsch M, Meissner E, Chanvillard C, Touze E, Pico F, Corcia P; ANZgene Consortium,{dagger}, Dörner T, Steinhagen-Thiessen E, Baeckman L, Heekeren HR, Li SC, Lindenberger U, Chan A, Hartung HP, Aktas O, Lohse P, Kümpfel T, Kubisch C, Epplen JT, Zettl UK, Fontaine B, Vandenbroeck K, Matesanz F, Urcelay E, Bertram L, Zipp F (2012). Closing the case of APOE in multiple sclerosis: no association with disease risk in over 29 000 subjects. J Med Genet. Sep;49(9):558-62. doi: 10.1136/jmedgenet-2012-101175. Erratum in: J Med Genet. 2012 Oct;49(10):668
  • Lill CM, Schjeide BM, Akkad DA, Blaschke P, Winkelmann A, Gerdes LA, Hoffjan S, Luessi F, Dörner T, Li SC, Steinhagen-Thiessen E, Lindenberger U, Chan A, Hartung HP, Aktas O, Lohse P, Kümpfel T, Kubisch C, Epplen JT, Zettl UK, Bertram L, Zipp F (2012). Independent replication of STAT3 association with multiple sclerosis risk in a large German case-control sample. Neurogenetics. Feb;13(1):83-6. doi: 10.1007/s10048-011-0305-6. Epub 2011 Nov 18
  • Schmitt I, Wüllner U, van Rooyen JP, Khazneh H, Becker J, Volk A, Kubisch C, Becker T, Kostic VS, Klein C, Ramirez A (2012). Variants in the 3'UTR of SNCA do not affect miRNA-433 binding and alpha-synuclein expression. Eur J Hum Genet. Dec;20(12):1265-9. doi: 10.1038/ejhg.2012.84. Epub 2012 May 23
  • von Ameln S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C (2012). A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet. Nov 2;91(5):919-27. doi: 10.1016/j.ajhg.2012.09.002. Epub 2012 Oct 18

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Tobias Lamkemeyer

  • Schulze J, Neupert S, Schmidt L, Predel R, Lamkemeyer T, Homberg U, Stengl M (2012). Myoinhibitory peptides in the brain of the cockroach Leucophaea maderae and colocalization with pigment-dispersing factor in circadian pacemaker cells. J Comp Neurol. Apr 1;520(5):1078-97. doi: 10.1002/cne.22785
  • Seeger-Nukpezah T, Liebau MC, Höpker K, Lamkemeyer T, Benzing T, Golemis EA, Schermer B (2012). The centrosomal kinase plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1. PLoS One. ;7(6):e38838. Epub 2012 Jun 11

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Thomas Langer

  • Almajan ER, Richter R, Paeger L, Martinelli P, Barth E, Decker T, Larsson NG, Kloppenburg P, Langer T, Rugarli EI (2012). AFG3L2 supports mitochon­drial protein synthesis and Purkinje cell survival. J Clin Invest. 122, 4048-4058. doi: 10.1172/JCI64604
  • Baker MJ, Mooga VP, Guiard B, Langer T, Ryan MT, Stojanovski D (2012). Impaired folding of the mitochondrial small TIM chaperones induces clearance by the i-AAA protease. J Mol Biol. 424, 227-239. doi: 10.1016/j.jmb.2012.09.019
  • Connerth M, Tatsuta T, Haag M, Klecker T, Westermann B, Langer T (2012). Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer pro­tein. Science. 338, 815-818. doi: 10.1126/science.1225625
  • Gerdes F, Tatsuta T, Langer T (2012). Mitochondrial AAA proteases - Towards a molecular understanding of membrane-bound proteolytic machines. Biochim Biophys Acta. 1823, 49-55. doi: 10.1016/j.bbamcr.2011.09.015
  • Klein JM, Busch JD, Potting C, Baker MJ, Langer T, Schwarz G (2012). The mitochondrial amidoxime-reducing component (mARC1) is a novel signal-anchored protein of the outer mitochondrial membrane. J Biol Chem. 287, 42795-42803. doi: 10.1074/jbc.M112.419424
  • Merkwirth C, Martinelli P, Korwitz A, Morbin M, Brönnecke HS, Jordan SD, Rugarli EI, Langer T (2012). Loss of prohibitin membrane scaffolds impairs mito­chondrial architecture and leads to tau hyperphosphorylation and neurodegener­a­tion. PLoS Genet. 8:e1003021. doi: 10.1371/journal.pgen.1003021
  • Rugarli EI, Langer T (2012). Mitochondrial quality control: A matter of life and death for neurons. EMBO J. 31, 1336-1349. doi: 10.1038/emboj.2012.38
  • Wai T, Langer T (2012). Chapter 146. The i-AAA Protease. Handbook of Proteolytic Enzymes (Third Ed) (pp. 1–7). Elsevier Ltd. doi:10.1016/B978-0-12-382219-2.00146-0

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Nils-Göran Larsson

  • Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, Götz A, Forsström S, Salven P, Angers-Loustau A, Kopra OH, Tyynismaa H, Larsson NG, Wartiovaara K, Prolla T, Trifunovic A, Suomalainen A (2012). Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice. Cell Metab. Jan 4;15(1):100-9
  • Almajan ER, Richter R, Paeger L, Martinelli P, Barth E, Decker T, Larsson NG, Kloppenburg P, Langer T, Rugarli EI (2012). AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival.
 J Clin Invest. Nov 1;122(11):4048-58. doi: 10.1172/JCI64604. Epub 2012 Oct 8
  • Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012). Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet. Oct 7. doi: 10.1038/ng.2427
  • Lee S, Sterky FH, Mourier A, Terzioglu M, Cullheim S, Olson L, Larsson NG (2012). Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons. Hum Mol Genet. Nov 15;21(22):4827-35. doi: 10.1093/hmg/dds352. Epub 2012 Aug 21
  • Naess K, Barbaro M, Bruhn H, Wibom R, Nennesmo I, von Döbeln U, Larsson NG, Nemeth A, Lesko N (2012). Complete Deletion of a POLG1 Allele in a Patient with Alpers Syndrome. J. Inherit. Metab. Dis. Rep. 2012:4:67-73
  • Ruzzenente B, Metodiev MD, Wredenberg A, Bratic A, Park CB, Cámara Y, Milenkovic D, Zickermann V, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Brandt U, Stewart JB, Gustafsson CM, Larsson NG (2012). LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs EMBO J. 2012:31:443-456
  • Shi Y, Dierckx A, Wanrooij PH, Wanrooij S, Larsson NG, Wilhelmsson LM, Falkenberg M, Gustafsson CM (2012). Mammalian transcription factor A is a core component of the mitochondrial transcription machinery. Proc. Natl. Acad. Sci. USA:109:16510-16515
  • Spåhr H, Habermann B, Gustafsson CM, Larsson NG, Hallberg BM (2012). Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. Proc. Natl. Acad. Sci. USA:109:15253-15258
  • Sterky FH, Hoffman AF, Milenkovic D, Bao B, Paganelli A, Edgar D, Wibom R, Lupica CR, Olson L, Larsson NG (2012). Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons. Hum Mol Genet. Mar 1;21(5):1078-89. Epub 2011 Nov 16
  • Vernochet C, Mourier A, Bezy O, Macotela Y, Boucher J, Rardin MJ, An D, Lee KY, Ilkayeva OR, Zingaretti CM, Emanuelli B, Smyth G, Cinti S, Newgard CB, Gibson BW, Larsson NG, Kahn CR (2012). Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance. Cell Metab. Dec 5;16(6):765-76. doi: 10.1016/j.cmet.2012.10.016. Epub 2012 Nov 15
  • Wanrooij S, Miralles Fusté J, Stewart JB, Wanrooij PH, Samuelsson T, Larsson NG, Gustafsson CM, Falkenberg M (2012). In vivo mutagenesis reveals that OriL is essential for mitochondrial DNA replication. EMBO Rep. Dec;13(12):1130-7. doi: 10.1038/embor.2012.161. Epub 2012 Oct 23

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Ivan Matic

  • Leidecker O, Matic I, Mahata B, Pion E, Xirodimas DP (2012). The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions. Cell Cycle. 2012, 11, (6), 1142-50
  • Matic I, Ahel  I, Hay RT (2012). Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites. Nature Methods. 2012, Jul 30;9(8):771-2
  • Matic I, Hay RT (2012). Detection and quantitation of SUMO chains by mass spectrometry. Methods in molecular biology. 2012, 832, 239-47
  • Miller C, Matic I, Maier K, Schwalb B, Roether S, Straesser K, Tresch A, Mann M, Cramer P (2012). Mediator phosphorylation prevents stress response transcription during non-stress conditions. The Journal of Biological Chemistry. 2012 Nov 7

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Roman-Ulrich Müller

  • Burst V, Pütsch F, Kubacki T, Völker LA, Bartram MP, Müller RU, Gillis M, Kurschat CE, Grundmann F, Müller-Ehmsen J, Benzing T, Teschner S (2012). Survival and distribution of injected haematopoietic stem cells in acute kidney injury. Nephrol Dial Transplant. Nov. 2012
  • Habbig S, Bartram MP, Sägmüller JG, Griessmann A, Franke M, Müller RU, Schwarz R, Hoehne M, Bergmann C, Tessmer C, Reinhardt HC, Burst V, Benzing T, Schermer B (2012). The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Hum Mol Genet. Oct. 2012
  • Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis, The EMBO Journal. Aug. 2012
  • Müller RU, Benzing T (2012). A Photo Shoot of Proteinuria: Zebrafish Models of Inducible Podocyte Damage. J Am Soc Nephrol. May 2012

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Pierluigi Nicotera

  • Michod D, Bartesaghi S, Khelifi A, Bellodi C, Berliocchi L, Nicotera P, Salomoni P (2012). Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron. Apr 12;74(1):122-35

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Carien Niessen

  • Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Brüning JC (2012). vascular endothelial IR/IGF-1R signaling controls skin wound vasculariziation. Biochem Biophys Res Commun. 421: 197-202
  • Behrendt K, Klatte J, Pofahl R, Bloch W, Smyth N, Tscharntke M, Krieg T, Paus R, Niessen CM, Niemann C, Brakebusch C, Haase I (2012). A function for Rac1 in the terminal differentiation and pigmentation of hair. J Cell Science. 125: 896-905
  • Boggetti B, Niessen CM (2012). Adherens junctions in mammalian development, homeostasis and disease: lessons from mice. Subcell Biochem. 60: 321-355
  • Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Michels C, Sandhoff K, Niessen CM, Niemann C (2012). Lef1 mediated control of lipid metabolism regulates skin barrier function. J Invest Derm. 132:337-345
  • Neuhaus B, Niessen CM, Mesaros A, Withers DJ, Krieg T, Partridge L (2012). Experimental analysis of risk factors for ulcerative dermatitis in mice. Exp Dermatol. 21: 712-713
  • Niessen MT, Iden S, Niessen CM (2012). The in vivo function of mammalian cell and tissue polarity regulators- how to shape and maintain the epidermal barrier. J Cell Science. 125: 3501-3510
  • Ninomiya H, David R, Damm EW, Fagotto F, Niessen CM, Winklbauer R (2012). Cadherin-dependent differential cell adhesion in Xenopus causes cell sorting in vitro, but not in the embryo. J Cell Science. 125: 1877-1883
  • Saiti M, Tucker DK, Kohlhorst D, Niessen CM, Kowalczyk AP (2012). Classical and desmosomal cadherins at a glance. J Cell Science. 125: 2547-2552

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Angelika A. Noegel

  • Chang GS, Noegel AA, Mavrich TN, Müller R, Tomsho L, Ward E, Felder M, Jiang C, Eichinger L, Glöckner G, Schuster SC, Pugh BF (2012). Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium. Genome Res. Jun;22(6):1098-106. Epub 2012 Mar 20
  • Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Wajid M, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P (2012). A Truncating Mutation of CEP135 is associated with primary microcephaly and disturbed centrosomal function. Am J Hum Genet. doi:101016/ajgh.2012.03.015
  • Klionsky DJ, et al. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544
  • Lu W, Schneider M, Neumann S, Jaeger VM, Taranum S, Munck M, Cartwright S, Richardson C, Carthew J, Noh K, Goldberg M, Noegel AA, Karakesisoglou I (2012). Nesprin interchain associations control nuclear size. Cell Mol Life Sci. Jun 1.; 69, 3493-3509
  • Rashmi RN, Eckes B, Glöckner G, Groth M, Neumann S, Gloy J, Sellin L, Walz G, Schneider M, Karakesisoglou I, Eichinger L, Noegel AA (2012). The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus. Mar 1;3(2):172-186. Epub 2012 Mar 1
  • Sultana H, Neelakanta G, Rivero F, Blau-Wasser R, Schleicher M, Noegel AA (2012). Ectopic expression of Cyclase associated protein CAP restores the streaming and aggregation defects of Adenylyl Cyclase A deficient Dictyostelium discoideum cells. BMC Dev Biol. Jan 12;12(1):3
  • Taranum S, Sur I, Müller R, Lu W, Rashmi RN, Munck M, Neumann S, Karakesisoglou I, Noegel AA (2012). Cytoskeletal interactions at the nuclear envelope mediated by nesprins. Int J Cell Biol. 2012:736524. Epub 2012 Feb 7
  • Taranum S, Vaylann E, Meinke P, Abraham S, Yang L, Neumann S, Karakesisoglou I, Wehnert M, Noegel AA (2012). LINC complex alterations in DMD and EDMD/CMT fibroblasts. Eur J Cell Biol. Aug;91(8):614-28. Epub 2012 May 1
  • Xavier CP, Rastetter RH, Blömacher M, Stumpf M, Himmel M, Morgan RO, Fernandez MP, Wang C, Osman A, Miyata Y, Gjerset RA, Eichinger L, Hofmann A, Linder S, Noegel AA, Clemen CS (2012). Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration. Sci Rep. 2012;2:241. Epub 2012 Jan 31. PMID: 22355754

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Peter Nürnberg

  • Amen S von, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C (2012). A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet. Nov 2;91(5):919-27. doi: 10.1016/j.ajhg.2012.09.002. Epub 2012 Oct 18
  • Asharani PV, Keupp K, Semler O, Wang W, Li Y, Thiele H, Yigit G, Pohl E, Becker J, Frommolt P, Sonntag C, Altmüller J, Zimmermann K, Greenspan DS, Akarsu NA, Netzer C, Schönau E, Wirth R, Hammerschmidt M, Nürnberg P, Wollnik B, Carney TJ (2012). Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet. Apr 6;90(4):661-74
  • Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Thiele H, Edwards A, Arends MJ, Miró X, White JK, Désir J, Abramowicz M, Dentici ML, Lepri F, Hofmann K, Har-Zahav A, Ryder E, Karp NA, Estabel J, Gerdin AK, Podrini C, Ingham NJ, Altmüller J, Nürnberg G, Frommolt P, Abdelhak S, Pasmanik-Chor M, Konen O, Kelley RI, Shohat M, Nürnberg P, Flint J, Steel KP, Hoppe T, Kubisch C, Adams DJ, Borck G (2012). Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. Dec 7;91(6):998-1010. doi: 10.1016/j.ajhg.2012.10.011. Epub 2012 Nov 29
  • Bendon CL, Fenwick AL, Hurst JA, Nürnberg G, Nürnberg P, Wall SA, Wilkie AO, Johnson D (2012). Frank-ter Haar syndrome associated with sagittal craniosynostosis and raised intracranial pressure. BMC Med Genet. Nov 9;13:104. doi: 10.1186/1471-2350-13-104
  • Bettecken T, Frenkel ZM, Altmüller J, Nürnberg P, Trifonov EN (2012). Apoptotic cleavage of DNA in human lymphocyte chromatin shows high sequence specificity. J Biomol Struct Dyn. Jun;30(2):211-6
  • Borck G, Shin BS, Stiller B, Mimouni-Bloch A, Thiele H, Kim JR, Thakur M, Skinner C, Aschenbach L, Smirin-Yosef P, Har-Zahav A, Nürnberg G, Altmüller J, Frommolt P, Hofmann K, Konen O, Nürnberg P, Munnich A, Schwartz CE, Gothelf D, Colleaux L, Dever TE, Kubisch C, Basel-Vanagaite L (2012). eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation. Mol Cell. Nov 30;48(4):641-6. doi: 10.1016/j.molcel.2012.09.005. Epub 2012 Oct 11
  • Borck G, Kakar N, Hoch J, Friedrich K, Freudenberg J, Nürnberg G, Yilmaz R, Daud S, Baloch DM, Nürnberg P, Oldenburg J, Ahmad J, Kubisch C (2012). An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group. Hum Genet. Feb;131(2):209-16. doi: 10.1007/s00439-011-1062-1. Epub 2011 Jul 15
  • Chaki M, Airik R, Ghosh AK, Giles RH, Chen R, Slaats GG, Wang H, Hurd TW, Zhou W, Cluckey A, Gee HY, Ramaswami G, Hong CJ, Hamilton BA, Cervenka I, Ganji RS, Bryja V, Arts HH, van Reeuwijk J, Oud MM, Letteboer SJ, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer JA, Schermer B, Liebau MC, Benzing T, Le Corre S, Drummond I, Janssen S, Allen SJ, Natarajan S, O'Toole JF, Attanasio M, Saunier S, Antignac C, Koenekoop RK, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson JG, Andreoli SP, Doherty DG, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud EB, Al-Rajhi AA, Lewis RA, Omran H, Lee EY, Wang S, Sekiguchi JM, Saunders R, Johnson CA, Garner E, Vanselow K, Andersen JS, Shlomai J, Nurnberg G, Nürnberg P, Levy S, Smogorzewska A, Otto EA, Hildebrandt F (2012). Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell. Aug 3;150(3):533-48. doi: 10.1016/j.cell.2012.06.028
  • Coelho D, Kim JC, Miousse IR, Fung S, du Moulin M, Buers I, Suormala T, Burda P, Frapolli M, Stucki M, Nürnberg P, Thiele H, Robenek H, Höhne W, Longo N, Pasquali M, Mengel E, Watkins D, Shoubridge EA, Majewski J, Rosenblatt DS, Fowler B, Rutsch F, Baumgartner MR (2012). Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. Nat Genet. Oct;44(10):1152-5. doi: 10.1038/ng.2386. Epub 2012 Aug 26
  • Eisenberger T, Slim R, Mansour A, Nauck M, Nürnberg G, Nürnberg P, Decker C, Dafinger C, Ebermann I, Bergmann C, Bolz HJ (2012). Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3. Orphanet J Rare Dis. Sep 2;7:59. doi: 10.1186/1750-1172-7-59
  • EPICURE Consortium, Leu C, de Kovel CG, Zara F, Striano P, Pezzella M, Robbiano A, Bianchi A, Bisulli F, Coppola A, Giallonardo AT, Beccaria F, Trenité DK, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Kleefuss-Lie AA, Hallman K, Kunz WS, Elger CE, Muhle H, Stephani U, Møller RS, Hjalgrim H, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Nabbout R, Baulac S, Leguern E, Serratosa JM, Rosenow F, Feucht M, Unterberger I, Covanis A, Suls A, Weckhuysen S, Kaneva R, Caglayan H, Turkdogan D, Baykan B, Bebek N, Ozbek U, Hempelmann A, Schulz H, Rüschendorf F, Trucks H, Nürnberg P, Avanzini G, Koeleman BP, Sander T (2012). Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies. Epilepsia. 2012 Feb;53(2):308-18. doi: 10.1111/j.1528-1167.2011.03379.x. Epub Jan 13
  • Frommolt P, Abdallah AT, Altmüller J, Motameny S, Thiele H, Becker C, Stemshorn K, Fischer M, Freilinger T, Nürnberg P (2012). Assessing the enrichment performance in targeted resequencing experiments. Hum Mutat. 2012 Apr;33(4):635-41. doi: 10.1002/humu.22036. Epub Feb 28
  • Halevy A, Basel-Vanagaite L, Shuper A, Helman S, Har-Zahav A, Birk E, Maya I, Kornreich L, Inbar D, Nürnberg G, Nürnberg P, Steinberg T, Straussberg R (2012). Microcephaly-Thin Corpus Callosum Syndrome Maps to 8q23.2-q24.12. Pediatr Neurol. Jun;46(6):363-8
  • Horvath R, Holinski-Feder E, Neeve VC, Pyle A, Griffin H, Ashok D, Foley C, Hudson G, Rautenstrauss Phd B, Nürnberg G, Nürnberg P, Kortler J, Neitzel B, Bäßmann I, Rahman T, Keavney B, Loughlin J, Hambleton S, Schoser B, Lochmüller H, Santibanez-Koref M, Chinnery PF (2012). A new phenotype of brain iron accumulation with dystonia, optic atrophy, and peripheral neuropathy. Mov Disord. 2012 May;27(6):789-93. doi: 10.1002/mds.24980. Epub Apr 16
  • Huppke P, Brendel C, Kalscheuer V, Korenke GC, Marquardt I, Freisinger P, Christodoulou J, Hillebrand M, Pitelet G, Wilson C, Gruber-Sedlmayr U, Ullmann R, Haas S, Elpeleg O, Nürnberg G, Nürnberg P, Dad S, Møller LB, Kaler SG, Gärtner J (2012). Mutations in SLC33A1 cause a lethal autosomal-recessive disorder with congenital cataracts, hearing loss, and low serum copper and ceruloplasmin. Am J Hum Genet. Jan 13;90(1):61-8. Erratum in: Am J Hum Genet. 2012 Feb 10;90(2):378
  • Hussain MS, Bakhtiar SM, Farooq M, Anjum I, Janzen E, Toliat MR, Eiberg H, Kjaer KW, Tommerup N, Noegel AA, Nürnberg P, Baig SM, Hansen L (2012). Genetic heterogeneity in Pakistani microcephaly families. Clin Genet. Jul 6;9999(999A). doi: 10.1111/j.1399-0004.2012.01932.x. Epub 2012 Aug 7
  • Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P (2012). A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. May 4;90(5):871-8. Epub Apr 19
  • Kakar N, Goebel I, Daud S, Nürnberg G, Agha N, Ahmad A, Nürnberg P, Kubisch C, Ahmad J, Borck G (2012). A homozygous splice site mutation in TRAPPC9 causes intellectual disability and microcephaly. Eur J Med Genet. Dec;55(12):727-31. doi: 10.1016/j.ejmg.2012.08.010. Epub 2012 Aug 30
  • Kumar S, Rathkolb B, Budde BS, Nürnberg P, de Angelis MH, Aigner B, Schneider MR (2012). Gsdma3(I359N) is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis. J Dermatol Sci. Sep;67(3):190-2. doi: 10.1016/j.jdermsci.2012.05.001. Epub 2012 May 11
  • Kumar S, Rathkolb B, Budde BS, Nürnberg P, de Angelis MH, Aigner B, Schneider MR (2012). Gsdma3(I359N) is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis. J Dermatol Sci. May 11. Published online 2015 Jun 24
  • Lessel D, Gamulin M, Kulis T, Toliat MR, Grgic M, Friedrich K, Zunec R, Balija M, Nürnberg P, Kastelan Z, Högel J, Kubisch C (2012). Replication of genetic susceptibility loci for testicular germ cell cancer in the Croatian population. Carcinogenesis. Jun 27. Epub 2012 Jun 27
  • Meimaridou E, Kowalczyk J, Guasti L, Hughes CR, Wagner F, Frommolt P, Nürnberg P, Mann NP, Banerjee R, Saka HN, Chapple JP, King PJ, Clark AJ, Metherell LA (2012). Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency. Nat Genet. May 27;44(7):740-2. doi: 10.1038/ng.2299
  • Olbrich H, Schmidts M, Werner C, Onoufriadis A, Loges NT, Raidt J, Banki NF, Shoemark A, Burgoyne T, Al Turki S, Hurles ME; UK10K Consortium, Köhler G, Schroeder J, Nürnberg G, Nürnberg P, Chung EM, Reinhardt R, Marthin JK, Nielsen KG, Mitchison HM, Omran H (2012). Recessive HYDIN mutations cause primary ciliary dyskinesia without randomization of left-right body asymmetry. Am J Hum Genet. Oct 5;91(4):672-84. doi: 10.1016/j.ajhg.2012.08.016. Epub 2012 Sep 27
  • Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Carter SL, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z, Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DA, Snijders PJ, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK (2012). Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. Oct;44(10):1104-10. doi: 10.1038/ng.2396. Epub 2012 Sep 2
  • Quednow BB, Brinkmeyer J, Mobascher A, Nothnagel M, Musso F, Gründer G, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker TF, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Mössner R, Maier W, Gallinat J, Diaz-Lacava A, Toliat MR, Thiele H, Nürnberg P, Wagner M, Winterer G (2012). Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6271-6. Epub Mar 26
  • Rosewich H, Thiele H, Ohlenbusch A, Maschke U, Altmüller J, Frommolt P, Zirn B, Ebinger F, Siemes H, Nürnberg P, Brockmann K, Gärtner J. (2012). Heterozygous de-novo mutations in ATP1A3 in patients with alternating hemiplegia of childhood: a whole-exome sequencing gene-identification study. Lancet Neurol. Sep;11(9):764-73. doi: 10.1016/S1474-4422(12)70182-5. Epub 2012 Jul 30
  • Weterman MA, Sorrentino V, Kasher PR, Jakobs ME, van Engelen BG, Fluiter K, de Wissel MB, Sizarov A, Nürnberg G, Nürnberg P, Zelcer N, Schelhaas HJ, Baas F (2012). A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy. Hum Mol Genet. Jan 15;21(2):358-70. Epub 2011 Oct 19
  • Yuksel-Apak M, Bögershausen N, Pawlik B, Li Y, Apak S, Uyguner O, Milz E, Nürnberg G, Karaman B, Gülgören A, Grzeschik KH, Nürnberg P, Kayserili H, Wollnik B (2012). A large duplication involving the IHH locus mimics acrocallosal syndrome. Eur J Hum Genet. Jun;20(6):639-44. doi: 10.1038/ejhg.2011.250. Epub 2012 Jan 11

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Linda Partridge

  • Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Bruning JC (2012). Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun. May 4;421(2):197-202. Epub 2012 Apr 4
  • Alic N, Hoddinott MP, Foley A, Slack C, Piper MD, Partridge L (2012). Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. PLoS ONE. 7, e45367
  • Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE (2012). The place of genetics in ageing research. Nat Rev Genet. Jul 10.; 589-594. doi: 10.1038/nrg3290
  • Chen Y, Lee SF, Blanc E, Reuter C, Wertheim B, Martinez-Diaz P, Hoffmann AA, Partridge L (2012). Genome-wide transcription analysis of clinal genetic variation in Drosophila. PLoS One. 2012;7(4):e34620. Epub Apr 13
  • Cochemé HM, Logan A, Prime TA, Abakumova I, Quin C, McQuaker SJ, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Hartley RC, Partridge L, Murphy MP (2012). Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nat Protoc. Apr 19;7(5):946-58. doi: 10.1038/nprot.2012.035
  • Gioti A, Wigby S, Wertheim B, Schuster E, Martinez P, Pennington CJ, Partridge L, Chapman T (2012). Sex peptide of Drosophila melanogaster males is a global regulator of reproductive processes in females. P Roy Soc B-Biol Sci. 279, 4423-4432
  • Neuhaus B, Niessen CM, Mesaros A, Withers DJ, Krieg T, Partridge L (2012). Experimental analysis of risk factors for ulcerative dermatitis in mice. Exp Dermatol. Sep;21(9):712-3. doi: 10.1111/j.1600-0625.2012.01558.x
  • Niccoli T, Partridge L (2012). Ageing as a risk factor for disease. Curr Biol. Sep 11;22(17):R741-52. doi: 10.1016/j.cub.2012.07.024. Review
  • Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton JM (2012). Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. PLoS ONE 7, e50881
  • Partridge L (2012). Current developments at Philosophical Transactions of the Royal Society B. Philos Trans R Soc Lond B Biol Sci. 2012 Jan 12;367(1585):3
  • Partridge L (2012). Diet and healthy aging. N Engl J Med. Dec 27;367(26):2550-1. doi: 10.1056/NEJMcibr1210447
  • Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L (2012). Ageing Increases Vulnerability to Aβ42 Toxicity in Drosophila. PLoS ONE. 7, e40569
  • Selman C, Partridge L (2012). A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice. Cell Cycle. Jan 1;11(1):17-8. Epub 2012 Jan 1
  • Slack C, Foley A, Partridge L (2012). Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila. PLoS ONE. 7, e47699

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Manolis Pasparakis

  • Brähler S, Ising C, Hagmann H, Rasmus M, Hoehne M, Kurschat C, Kisner T, Goebel H, Shankland SJ, Addicks K, Thaiss F, Schermer B, Pasparakis M, Benzing T, Brinkkoetter PT (2012). Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. Am J Physiol Renal Physiol. Am J Physiol Renal Physiol. 303(10):F1473-85
  • Chang JH, Xiao Y, Hu H, Jin J, Yu J, Zhou X, Wu X, Johnson HM, Akira S, Pasparakis M, Cheng X, Sun SC (2012). Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells. Nat Immunol. 13(5):481-90
  • Maelfait J, Roose K, Bogaert P, Sze M, Saelens X, Pasparakis M, Carpentier I, van Loo G, Beyaert R (2012). A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection. PLoS Pathog. 2012;8(3):e1002570. Erratum in: PLoS Pathog. 2012, 8(4): doi/10.1371/annotation/a2136b9a-3cbf-426f-9cfb-73e3c9c6396d
  • Pasparakis M (2012). Role of NF-kB in epithelial biology. Immunol Rev. 246(1):346-58
  • Polykratis A, van Loo G, Xanthoulea S, Hellmich M, Pasparakis M (2012). Conditional Targeting of TRAF6 Reveals Opposing Functions of TLR Signaling in Endothelial and Myeloid Cells in a Mouse Model of Atherosclerosis. Circulation. 126(14):1739-51
  • Welz PS, Pasparakis M (2012). A way to DAI. Cell Host Microbe. 11(3):223-5
  • Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012). CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood. 120(3):613-25
  • Wolf MJ, Hoos A, Bauer J, Boettcher S, Knust M, Weber A, Simonavicius N, Schneider C, Lang M, Stürzl M, Croner RS, Konrad A, Manz MG, Moch H, Aguzzi A, van Loo G, Pasparakis M, Prinz M, Borsig L, Heikenwalder M (2012). Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway. Cancer Cell. 22(1):91-105
  • Wohlleber D, Kashkar H, Gärtner K, Frings MK, Odenthal M, Hegenbarth S, Börner C, Arnold B, Hämmerling G, Nieswandt B, van Rooijen N, Limmer A, Cederbrant K, Heikenwalder M, Pasparakis M, Protzer U, Dienes HP, Kurts C, Krönke M, Knolle PA (2012). TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation. Cell Rep. 2012, 2(3):478-87            

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Mats Paulsson

  • Agarwal P, Zwolanek D, Keene DR, Schulz JN, Blumbach K, Heinegård D, Zaucke F, Paulsson M, Krieg T, Koch M, Eckes B (2012). Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure. J Biol Chem. ;287(27):22549-59. Epub 2012 May 9
  • Bechtel M, Keller MV, Bloch W, Sasaki T, Boukamp P, Zaucke F, Paulsson M, Nischt R (2012). Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures. FASEB J. 2 (9):3637-48. Epub 2012 May 23
  • Groma G, Xin W, Grskovic I, Niehoff A, Brachvogel B, Paulsson M, Zaucke F (2012). Abnormal bone quality in cartilage oligomeric matrix protein and matrilin 3 double-deficient mice caused by increased tissue inhibitor of metalloproteinases 3 deposition and delayed aggrecan degradation. Arthritis Rheum. 64(8):2644-54. doi: 10.1002/art.34435
  • Grskovic I, Kutsch A, Frie C, Groma G, Stermann J, Schlötzer-Schrehardt U, Niehoff A, Moss SE, Rosenbaum S, Pöschl E, Chmielewski M, Rappl G, Abken H, Bateman JF, Cheah KS, Paulsson M, Brachvogel B (2012). Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. J Bone Miner Res. Nov;27(11):2399-412. doi: 10.1002/jbmr.1682
  • John S, Thiebach L, Frie C, Mokkapati S, Bechtel M, Nischt R, Rosser-Davies S, Paulsson M, Smyth N (2012). Epidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrier. PLoS One. 7, e34252
  • Sabatelli P, Gualandi F, Gara SK, Grumati P, Zamparelli A, Martoni E, Pellegrini C, Merlini L, Ferlini A, Bonaldo P, Maraldi NM, Paulsson M, Squarzoni S, Wagener R (2012). Expression of collagen VI α5 and α6 chains in human muscle and in Duchenne muscular dystrophy-related muscle fibrosis. Matrix Biol. (3):187-96. Epub 2011 Dec 30
  • Schiavinato A, Becker AK, Zanetti M, Corallo D, Milanetto M, Bizzotto D, Bressan G, Guljelmovic M, Paulsson M, Wagener R, Braghetta P, Bonaldo P (2012). EMILIN-3, peculiar member of elastin microfibril interface-located protein (EMILIN) family, has distinct expression pattern, forms oligomeric assemblies, and serves as transforming growth factor β (TGF-β) antagonist. J Biol Chem. 287(14):11498-515. Epub 2012 Feb 10
  • Wintgens KF, Dschietzig T, Stoeva S, Paulsson M, Armbruster FP (2012). Plasma myostatin measured by a competitive ELISA using a highly specific antiserum. Clin Chim Acta. 413(15-16):1288-94. Epub 2012 Apr 25 

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Alvaro Rada-Iglesias

  • Rada-Iglesias A, Bajpai R, Prescott SL, Brugmann S, Swigut T, Wysocka J (2012). Epigenomic mapping annotates human neural crest enhancers and predicts a new role for nuclear receptors NR2F1/2. Cell Stem Cell. Nov 2;11(5):633-48

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Hans Christian Reinhardt

  • Boucas J, Höpker K, Chen S, Herter-Sprie GS, Jokic M, Riabinska A, Reinhardt HC (2012). Posttranscriptional regulation of gene expression – adding another layer of complexity to the DNA damage response. Frontiers in Genetics. 2012;3:159
  • Habbig S, Bartram MP, Sägmüller JG, Franke M, Müller RU, Schwarz R, Hoehne M, Bergmann C, Reinhardt HC, Burst V, Benzing T, Schermer B (2012). The ciliopathy disease protein NPHP9 controls nuclear delivery and activation of the oncogenic transcriptional regulator TAZ, Hum Mol Genet. 2012 Dec 15;21(26):5528-38
  • Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt HC (2012). Putting the brakes on p53-driven apoptosis. Cell Cycle. 2012 Sep 14;11(22)
  • Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos M, Thomas R, Lowery D, Fischer M, Roels F, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Medema R, Yaffe MB, Schermer B, Reinhardt HC, Benzing T (2012). AATF/Che1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J. 2012 Oct 17;31(20):3961-75
  • Reinhardt HC, Schumacher B (2012). The p53 network: Cellular and systemic DNA damage responses in aging and cancer, TRENDS in Genetics. 2012 Mar;28(3):128-36

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Nirmal Robinson

  • Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S (2012). Type-I interferon induces necroptosis in macrophages during Salmonella Typhimurium infection. Nature Immunology.  13(10):954-962

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Elena Rugarli

  • Almajan ER, Richter R, Paeger L, Martinelli P, Barth E, Decker T, Larsson NG, Kloppenburg P, Langer T, Rugarli E (2012). AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival.
 J Clin Invest. 2012 Nov 1;122(11):4048-58. doi: 10.1172/JCI64604. Epub 2012 Oct 8
  • Mancuso G, Barth E, Crivello P, Rugarli E (2012). Alternative splicing of Spg7, a gene involved in hereditary spastic paraplegia, encodes a variant of paraplegin targeted to the endoplasmic reticulum. PLoS One. ;7(5):e36337. Epub 2012 May 1
  • Merkwirth C, Martinelli P, Korwitz A, Morbin M, Brönneke HS, Jordan SD, Rugarli E, Langer T (2012). Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration. PLoS Genet. Nov;8(11):e1003021. doi: 10.1371/journal.pgen.1003021
  • Rugarli E, Langer T (2012). Mitochondrial quality control: a matter of life and death for neurons. EMBO J. Feb 21;31(6):1336-49. doi: 10.1038/emboj.2012.38

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Bernhard Schermer

  • Benzing T, Schermer B (2012). Clinical spectrum and pathogenesis of nephronophthisis. Curr Opin Nephrol Hypertens. 21: 272–8
  • Borgal L, Habbig S, Hatzold J, Liebau M, Dafinger C, Sacarea I, Hammerschmidt M, Benzing T, Schermer B (2012). The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate ?-catenin signaling. J Biol Chem. 287: 25370–80
  • Brähler S, Ising C, Hagmann H, Rasmus M, Hoehne M, Kurschat C, Kisner T, Goebel H, Shankland S, Addicks K, Thaiss F, Schermer B, Pasparakis M, Benzing T, Brinkkoetter P (2012). Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. Am J Physiol Renal Physiol. 303: F1473-85
  • Chaki M, Airik R, Ghosh A, Giles R, Chen R, Slaats G, Wang H, Hurd T, Zhou W, Cluckey A, Gee H, Ramaswami G, Hong C, Hamilton B, Cervenka I, Ganji R, Bryja V, Arts H, van Reeuwijk J, Oud M, Letteboer S, Roepman R, Husson H, Ibraghimov-Beskrovnaya O, Yasunaga T, Walz G, Eley L, Sayer J, Schermer B, Liebau M, Benzing T, Le Corre S, Drummond I, Janssen S, Allen S, Natarajan S, O’Toole J, Attanasio M, Saunier S, Antignac C, Koenekoop R, Ren H, Lopez I, Nayir A, Stoetzel C, Dollfus H, Massoudi R, Gleeson J, Andreoli S, Doherty D, Lindstrad A, Golzio C, Katsanis N, Pape L, Abboud E, Al-Rajhi A, Lewis R, Omran H, Lee E, Wang S, Sekiguchi J, Saunders R, Johnson C, Garner E, Vanselow K, Andersen J, Shlomai J, Nurnberg G, Nurnberg P, Levy S, Smogorzewska A, Otto E, Hildebrandt F (2012). Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell. 150: 533–48
  • Habbig S, Bartram M, Sägmüller J, Griessmann A, Franke M, Müller R, Schwarz R, Hoehne M, Bergmann C, Tessmer C, Reinhardt H, Burst V, Benzing T, Schermer B (2012). The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Hum Mol Genet. 21: 5528–38
  • Habbig S, Bartram M, Muller R, Benzing T, Schermer B (2012). The nephronophthisis proteins NPHP9 and NPHP4 corporately regulate Hippo-signaling. Eur J Pediatr. 171: 1430–1430
  • Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt H (2012). Putting the brakes on p53-driven apoptosis. Cell Cycle. 11: 4122–8
  • Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos M, Thomas R, Lowery D, Roels F, Fischer M, Liebau M, Resch U, Kisner T, Roether F, Bartram M, Mueller R, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema R, Yaffe M, Schermer B, Reinhardt Hc, Benzing T (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J. 31: 3961–3975
  • Khurshid S, Kurschat P, Niessen C, Schermer B, Benzing T, Hoepker K (2012). Apoptosis Antagonizing Transcription Factor AATF links DNA damage signaling to epidermal development and the maintenance of skin barrier function. J Invest Dermatol. 132: S104–S104
  • Liebau M, Dafinger C, Elsayed S, Fabretti F, Dosch J, Elsobky E, Benzing T, Bolz H, Schermer B (2012). The novel Joubert Gene KIF7 regulates microtubular dynamics and cellular polarity. Eur J Pediatr. 171: 1427–1427
  • Seeger-Nukpezah T, Liebau M, Höpker K, Lamkemeyer T, Benzing T, Golemis E, Schermer B (2012). The centrosomal kinase Plk1 localizes to the transition zone of primary cilia and induces phosphorylation of nephrocystin-1. PLoS ONE. 7: e38838
  • Völker L, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Hoehne M, Kaspert A (2012). Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol. 137: 355–366

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Markus Schubert

  • Becker K, Freude S, Zemva J, Stöhr O, Krone W, Schubert M (2012). Chronic peripheral hyperinsulinemia has no substantial influence on tau phosphorylation in vivo. Neurosci Lett. 16;516(2):306-10. Epub 2012 Apr 12
  • Blumbach K, Niehoff A, Belgardt BF, Ehlen HW, Schmitz M, Hallinger R, Schulz JN, Brüning JC, Krieg T, Schubert M, Gullberg D, Eckes B (2012). Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels. J Biol Chem. 287(9):6431-40. Epub 2011 Dec 30
  • Moll L, Schubert M (2012). The Role of Insulin and Insulin-Like Growth Factor-1/FoxO-Mediated Transcription for the Pathogenesis of Obesity-Associated Dementia. Curr Gerontol Geriatr Res. 2012;2012:384094. Epub 2012 May 13

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Björn Schumacher

  • Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Ulrich Müller R, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Christian Reinhardt H, Benzing T (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. EMBO J. 2012 Oct 17;31(20):3961-75
  • Reinhardt HC, Schumacher B (2012). The p53 network: Cellular and systemic DNA damage responses in aging and cancer. Trends Genet. 2012 Mar;28(3):128-36

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Günter Schwarz

  • Belaidi AA, Arjune S, Santamaria-Araujo JS, Sass JO, Schwarz G (2012). Molybdenum cofactor deficiency: a new HPLC method for fast quantification of S-sulfocysteine in urine and serum. J Inh Met Dis Reports. 2012;5:35-43. doi: 10.1007/8904_2011_89. Epub 2011 Dec 17
  • Herweg J, Schwarz G (2012). Splice-specific glycine receptor binding, folding, and phosphorylation of the scaffolding protein gephyrin. J Biol Chem. 2012 Apr 13;287(16):12645-56. doi: 10.1074/jbc.M112.341826. Epub 2012 Feb 17
  • Hitzert MM, Bos AF, Bergman KA, Veldman A, Schwarz G, Santamaria-Araujo JA, Heiner-Fokkema R, Sival DA, Lunsing RJ, Arjune S, Kosterink JGW, van Spronsen FJ (2012). Experimental Treatment with cPMP: Favorable Outcome in a Newborn with Molybdenum Cofactor Type A Deficiency. Pediatrics. 130: E1005-10
  • Klein JM, Busch JD, Potting C, Baker MJ, Langer T, Schwarz G (2012). The mitochondrial amidoxime-reducing component (mARC1) is a novel signal-anchored protein of the outer mitochondrial membrane. J Biol Chem. 2012 Oct 19. Epub 2012 Oct 19
  • Klein J, Schwarz G (2012). Cofactor-dependent maturation of mammalian sulfite oxidase links two mitochondrial import pathways. J Cell Sci. 125: 4876-85
  • Lambeck I, Fischer-Schrader K, Nick D, Röper J, Chi JC, Hille R, Schwarz G (2012). The molecular mechanism of 14-3-3-mediated inhibition of plant nitrate reductase. J Biol Chem. 287: 4562-4571
  • Santamaria-Araujo JA, Wray V, Schwarz G (2012). Structure and stability of the molybdenum cofactor intermediate cyclic pyranopterin monophosphate. J Biol Inorg Chem. 7: 113-122

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Philipp Steven

  • Gehlsen U, Oetke A, Szaszák M, Koop N, Paulsen F, Gebert A, Huettmann G, Steven P (2012). Two-photon fluorescence lifetime imaging monitors metabolic changes during wound healing of corneal epithelial cells in vitro. Graefes Arch Clin Exp Ophthalmol. 2012 Sep;250(9):1293-302. doi: 10.1007/s00417-012-2051-3. Epub 2012 May 6

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Wilhelm Stoffel

  • Jungblut M, Tiveron MC, Barral S, Abrahamsen B, Knöbel S, Pennartz S, Schmitz J, Perraut M, Pfrieger FW, Stoffel W, Cremer H, Bosio A (2012). Isolation and characterization of living primary astroglial cells using the new GLAST-specific monoclonal antibody ACSA-1. Glia. May;60(6):894-907. doi: 10.1002/glia.22322. Epub 2012 Feb 28
  • Schraven SP, Franz C, Rüttiger L, Löwenheim H, Lysakowski A, Stoffel W, Knipper M (2012). Altered phenotype of the vestibular organ in GLAST-1 null mice. J Assoc Res Otolaryngol. Jun;13(3):323-33. Epub 2012 Feb 14
  • Weeghel M van, Te Brinke H, van Lenthe H, Kulik W, Minkler PE, Stoll MS, Sass JO, Janssen U, Stoffel W, Schwab KO, Wanders RJ, Hoppel CL, Houten SM (2012). Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsaturated fatty acids. FASEB J.  26, 4316-26

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Aleksandra Trifunovic

  • Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, Götz A, Forsström S, Salven P, Angers-Loustau A, Kopra OH, Tyynismaa H, Larsson NG, Wartiovaara K, Prolla T, Trifunovic A, Suomalainen A (2012). Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice. Cell Metab. 2012 Jan 4;15(1):100-9

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Mirka Uhlirova

  • Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M (2012). Activating Transcription Factor 3 Regulates Immune and Metabolic Homeostasis. Mol Cell Biol. Jul 30. doi: 10.1128/ MCB.00429-12, Epub 2012 Jul 30

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Dario Valenzano

  • Origlia N, Valenzano DR, Moretti M, Gotti C, Domenici L (2012). Visual Acuity Is Reduced in Αlpha 7 Nicotinic Receptor Knockout Mice. Invest Ophth Vis Sci. 53 (3), 1211-1218

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David Vilchez

  • Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues AP, Manning G, Dillin A (2012). RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature. 489(7415): 263-268
  • Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, Spencer B, Page L, Masliah E, Gage FH, Dillin A (2012). Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 489(7415): 304-308

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Rudolf J. Wiesner

  • Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenković D, Wai T, Hagström E, Chatzidaki-Trinks E, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF (2012). Variation in germ-line mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission. Nat Genet. 44, 1282-1285
  • Franko A, von Kleist-Retzow JC, Böse M, Sanchez-Lasheras C, Brodesser S, Krut O, Kunz WS, Wiedermann D, Hoehn M, Stöhr O, Moll L, Freude S, Krone W, Schubert M, Wiesner RJ (2012). Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance impairs respiratory chain function in muscle. J Mol Med. 90, 1145-1160
  • Hornig-Do HT, Tatsuta T, Buckermann A, Bust M, Kolberg G, Rötig A, Hellmich H, Nijtmans L, Wiesner RJ (2012). Nonsense mutations in the COX1 subunit impair the stability of respiratory chain complexes rather than their assembly. EMBO J. 31,1293-307
  • Zemva J, Schilbach K, Stöhr O, Moll L, Franko A, Krone W, Wiesner RJ, Schubert M (2012). Central FoxO3a and 6 expression is downregulated in response to high fat diet induced diabetes but not during aging. Exp Clin Endocrinol Diabetes. 120, 340-350

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Andreas Wodarz

  • Gailite I, Egger-Adam D, Wodarz A (2012). The phosphoinositide-associated protein Rush hour regulates endosomal trafficking in Drosophila. Mol Biol Cell. 23, 433-447
  • Krahn MP, Wodarz A (2012). Phosphoinositide lipids and cell polarity: Linking the plasma membrane to the cytocortex. 
Essays Biochem. 53, 15-27
  • Giebel B, Wodarz A (2012). Notch signaling: Numb makes the difference. 
Curr Biol. 22, R133-135

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Bernd Wollnik

  • von Ameln S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C (2012). A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet. Nov 2;91(5):919-27. doi: 10.1016/j.ajhg.2012.09.002. Epub 2012 Oct 18
  • Semler O, Garbes L, Keupp K, Swan D, Zimmermann K, Becker J, Iden S, Wirth B, Eysel P, Koerber F, Schoenau E, Bohlander SK, Wollnik B, Netzer C (2012). A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus. Am J Hum Genet. Aug 10;91(2):349-57. doi: 10.1016/j.ajhg.2012.06.011. Epub 2012 Aug 2
  • Yuksel-Apak M, Bögershausen N, Pawlik B, Li Y, Apak S, Uyguner O, Milz E, Nürnberg G, Karaman B, Gülgören A, Grzeschik KH, Nürnberg P, Kayserili H, Wollnik B (2012). A large duplication involving the IHH locus mimics acrocallosal syndrome. Eur J Hum Genet. Jan 11. doi: 10.1038/ejhg.2011.250. Epub 2012 Jan 11
  • Asharani PV, Keupp K, Semler O, Wang W, Li Y, Thiele H, Yigit G, Pohl E, Becker J, Frommolt P, Sonntag C, Altmüller J, Zimmermann K, Greenspan DS, Akarsu NA, Netzer C, Schönau E, Wirth R, Hammerschmidt M, Nürnberg P, Wollnik B, Carney TJ (2012). Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet. Apr 6;90(4):661-74

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Thomas Wunderlich

  • Peche VS, Holak TA, Burgute BD, Kosmas K, Kale SP, Wunderlich FT, Elhamine F, Stehle R, Pfitzer G, Nohroudi K, Addicks K, Stöckigt F, Schrickel JW, Gallinger J, Schleicher M, Noegel AA (2012). Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci. Sep 4. Epub 2012 Sep 4
  • Whitham M, Chan MH, Pal M, Matthews VB, Prelovsek O, Lunke S, El-Osta A, Broenneke H, Alber J, Brüning JC, Wunderlich FT, Lancaster GI, Febbraio MA (2012). Contraction-induced Interleukin-6 Gene Transcription in Skeletal Muscle Is Regulated by c-Jun Terminal Kinase/Activator Protein-1. J Biol Chem. Mar 30;287(14):10771-9. Epub 2012 Feb 18
  • Wunderlich CM, Delić D, Behnke K, Meryk A, Ströhle P, Chaurasia B, Al-Quraishy S, Wunderlich F, Brüning JC, Wunderlich FT (2012). Cutting edge: Inhibition of IL-6 trans-signaling protects from malaria-induced lethality in mice. J Immunol. May 1;188(9):4141-4. Epub 2012 Mar 30

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