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Publications 2008

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Adam Antebi

  • Fielenbach N, Antebi A (2008). C. elegans dauer formation and the molecular basis of plasticity. Genes Dev. Aug 15;22(16):2149-65. Review
  • Giroux S, Bethke A, Fielenbach N, Antebi A, Corey EJ (2008). Syntheses and biological evaluation of B-ring-modified analogues of dafachronic acid A. Org Lett. Aug 21;10(16):3643-5. Epub 2008 Jul 19
  • Magner DB, Antebi A (2008). Caenorhabditis elegans nuclear receptors: insights into life traits. Trends Endocrinol Metab. Jul;19(5):153-60. Epub 2008 Apr 10. Review

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Hisham Bazzi

  • Fantauzzo KA, Bazzi H, Jahoda CA, Christiano AM (2008). Dynamic expression of the zinc-finger transcription factor trps1 during hair follicle morphogenesis and cycling. Gene Expr Pattern. 8(2), 51-7
  • Ishii Y, Wajid M, Bazzi H, Fantauzzo KA, Barber AG, Blaydon DC, Nam JS, Yoon JK, Kelsell DP, Christiano AM (2008). Mutations in R-Spondin 4 (RSPO4) underlie inherited anonychia. J Invest Dermatol. 128, 867-70
  • Owens P, Bazzi H, Engelking E, Han G, Christiano AM, Wang XJ (2008). Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity. Dev Biol. 322(1), 156-66

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Thomas Benzing

  • Bergmann C, Fliegauf M, Brüchle NO, Frank V, Olbrich H, Kirschner J, Schermer B, Schmedding I, Kispert A, Kränzlin B, Nürnberg G, Becker C, Grimm T, Girschick G, Lynch SA, Kelehan P, Senderek J, Neuhaus TJ, Stallmach T, Zentgraf H, Nürnberg P, Gretz N, Lo C, Lienkamp S, Schäfer T, Walz G, Benzing T, Zerres K, Omran H (2008). Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Am J Hum Genet. Apr;82(4):959-70. Epub 2008 Mar 27
  • Duning K, Schurek EM, Schlüter M, Bayer M, Reinhardt HC, Schwab A, Schaefer L, Benzing T, Schermer B, Saleem MA, Huber TB, Bachmann S, Kremerskothen J, Weide T, Pavenstädt H (2008). KIBRA modulates directional migration of podocytes. J Am Soc Nephrol. Oct;19(10):1891-903. Epub 2008 Jul 2 
  • Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB (2008). Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. Aug 22;283(34):23033-8. Epub 2008 Jun 18
  • Harvey SJ, Jarad G, Cunningham J, Goldberg S, Schermer B, Harfe BD, McManus MT, Benzing T, Miner JH (2008). Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol. Nov;19(11):2150-8. Epub 2008 Sep 5
  • Philippe A, Nevo F, Esquivel EL, Reklaityte D, Gribouval O, Tête MJ, Loirat C, Dantal J, Fischbach M, Pouteil-Noble C, Decramer S, Hoehne M, Benzing T, Charbit M, Niaudet P, Antignac C (2008). Nephrin mutations can cause childhood-onset steroid-resistant nephrotic syndrome. J Am Soc Nephrol. Oct;19(10):1871-8. Epub 2008 Jul 9

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Matteo Bergami

  • Bergami M, Rimondini R, Santi S, Blum R, Götz M, Canossa M (2008). Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior. Proc Natl Acad Sci U S A. 105:15570-15575
  • Bergami M, Santi S, Formaggio E, Cagnoli C, Verderio C, Blum R, Berninger B, Matteoli M, Canossa M (2008). Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes. J Cell Biol. 183:213-221

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Jens C. Brüning

  • Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC (2008). PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response. Cell Metab. Apr;7(4):291-301
  • Klöting N, Koch L, Wunderlich T, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M (2008). Autocrine IGF 1 action in adipocytes controls systemic IGF-1 concentrations and growth. Diabetes. Aug;57(8):2074-82. Epub 2008 Apr 28.
  • Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant  G, Kahn CR, Schwenk F, Brüning JC (2008). Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest. Jun;118(6):2132-47
  • Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC (2008). Activation of Stat3 signaling in AgRP neurons promotes locomotor activity. Cell Metab. 2008 Mar;7(3):236-48
  • Rother E, Könner AC, Brüning JC (2008). Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism. Am J Physiol Endocrinol Metab. May;294(5):E810-6. Epub 2008 Feb 19
  • Stachelscheid H, Ibrahim H, Koch L, Schmitz A, Tscharntke M, Wunderlich FT, Scott J, Michels C, Wickenhauser C, Haase I, Brüning JC, Niessen CM (2008). Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation. EMBO J. Aug 6;27(15):2091-101. Epub 2008 Jul 24
  • Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC (2008). Hepatic NF-kappa B essential modulatordeficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A. Jan 29;105(4):1297-302. Epub 2008 Jan 23

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Susanne Brodesser

  • Lastres-Becker I, Brodesser S, Lütjohann D, Azizov M, Buchmann J, Hintermann E, Sandhoff K, Schürmann A, Nowock J, Auburger G (2008). Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice. Hum Mol Genet. May 15;17(10):1465-81. Epub 2008 Feb 4

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Oliver A. Cornely

  • Cornely OA, Böhme A, Reichert D, Reuter S, Maschmeyer G, Maertens J, Buchheidt D, Paluszewska M, Arenz D, Bethe U, Effelsberg J, Lövenich H, Sieniawski M, Haas A, Einsele H, Eimermacher H, Martino R, Silling G, Hahn M, Wacker S, Ullmann AJ, Karthaus M (2008). Multinational Case Registry of the Infectious Diseases Working Party of the German Society for Hematology and Oncology. Risk factors for breakthrough invasive fungal infection during secondary prophylaxis. J Antimicrob Chemother. Apr;61(4):939 46. Epub 2008 Feb 12
  • Cornely OA, Ullmann AJ (2008). Numbers needed to treat with posaconazole prophylaxis to prevent invasive fungal infection and death. Clin Infect Dis. May 15;46(10):1626-7; author reply 1627-8
  • Glöckner A, Cornely OA (2008). Echinocandins in invasive candidiasis. Med Klin (Munich). 2008 Jun 15;103(6):397-405
  • Kaskel P, Tuschy S, Wagner A, Bannert C, Cornely OA, Glasmacher A, Lipp HP, Ullmann AJ (2008). Economic evaluation of caspofungin vs liposomal amphotericin B for empirical therapy of suspected systemic fungal infection in the German hospital setting. Ann Hematol. Apr;87(4):311-9. Epub 2007 Oct 11
  • Krishna G, AbuTarif M, Xuan F, Martinho M, Angulo D, Cornely OA (2008). Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome. Pharmacotherapy. Oct;28(10):1223-32
  • Lehmann C, Jung N, Hofmann A, Cornely OA, Wyen C, Fätkenheuer G, Hartmann P (2008) Nucleoside-free boosted double PI regimen: significant CD4+ T-cell recovery in patients with poor immunologic response despite virologic suppression. Curr HIV Res. Nov;6(6):555-9
  • Reinel D, Plettenberg A, Seebacher C, Abeck D, Brasch J, Cornely O, Effendy I, Ginter-Hanselmayer G, Haake N, Hamm G, Hipler UC, Hof H, Korting HC, Mayser P, Ruhnke M, Schlacke KH, Tietz HJ (2008). Oral candidiasis. J Dtsch Dermatol Ges. Jul;6(7):593-7
  • Rüping MJ, Albermann N, Ebinger F, Burckhardt I, Beisel C, Müller C, Vehreschild JJ, Kochanek M, Fätkenheuer G, Bangard C, Ullmann AJ, Herr W, Kolbe K, Hallek M, Cornely OA (2008). Posaconazole concentrations in the central nervous system. J Antimicrob Chemother. Dec;62(6):1468-70. Epub 2008 Sep 28
  • Rüping MJ, Vehreschild JJ, Cornely OA (2008). Patients at high risk of invasive fungal infections: when and how to treat. Drugs. 68(14):1941-62
  • Rüping MJ, Vehreschild JJ, Cornely OA (2008). Antifungal treatment strategies in high risk patients. Mycoses. Sep;51 Suppl 2:46-51
  • Vehreschild JJ, Böhme A, Reichert D, Kiehl MG, Arenz D, Pankraz K, Kochanek M, Ullmann AJ, Cornely OA (2008). Treatment of invasive fungal infections in clinical practice: a multi-centre survey on customary dosing, treatment indications, efficacy and safety of voriconazole. Int J Hematol. Mar;87(2):126-31. Epub 2008 Feb 21
  • Wolf HH, Leithäuser M, Maschmeyer G, Salwender H, Klein U, Chaberny I, Weissinger F, Buchheidt D, Ruhnke M, Egerer G, Cornely O, Fätkenheuer G, Mousset S (2008). Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Central venous catheter-related infections in hematology and oncology : guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Ann Hematol. Nov;87(11):863-76. Epub 2008 Jul 16

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Sabine Eming

  • Eming SA, Smola H, Malchau G, Krieg T, Smola-Hess S (2008). Polyacrylatesuperabsorber inhibits MMP activity in chronic wounds. Biomaterials. 29(19):2932-40
  • Eren M, Fabri M, Krieg T, Eming SA (2008). Pustulosis acuta generalisata with joint involvement in a HLA-A2 and HLA-B35 positive patient. J Am Acad Dermatol. 58(6):1056-8
  • Schuster J, Fabri M, Eming SA, Hunzelmann N (2008). Allergic drug eruption secondary to intravenous aciclovir. Acta Dermato-Venerologica. 88(2):196-8

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Lukas P. Frenzel

  • Hannes T, Halbach M, Nazzal R, Frenzel L, Saric T, Khalil M, Hescheler J, Brockmeier K, Pillekamp F (2008). Biological pacemakers: characterization in an in vitro coculture model. J Electrocardiol. Nov-Dec;41(6):562-6. Epub 2008 Sep 13
  • Sarić T, Frenzel LP, Hescheler J (2008). Immunological barriers to embryonic stem cell-derived therapies. Cells Tissues Organs.;188(1-2):78-90. Epub 2008 Feb 27. Review

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Peter Frommolt

  • Flesch M, Hagemeister J, Berger HJ, Schiefer A, Schynkowski S, Klein M, Sahebdjami S, vom Dahl S, Fehske W, Mies R, von Eiff M, Pfaff H, Frommolt P, Hoepp HW (2008). Implementation of guidelines for the treatment of acute ST-elevation myocardial infarction: the Cologne Infarction Model Registry. Circ Cardiovasc Interv. Oct;1(2):95-102. Epub 2008 Sep 3
  • Frommolt P, Thomas RK (2008). Standardized high-throughput evaluation of cell-based compound screens. BMC Bioinformatics. Nov 12;9:475
  • Kocher M, Frommolt P, Borberg SK, Rühl U, Steingräber M, Niewald M, Staar S, Stuschke M, Becker G, Fischedick AR, Herfarth K, Grauthoff H, Müller RP (2008). Randomized study of postoperative radiotherapy and simultaneous temozolomide without adjuvant chemotherapy for glioblastoma. Strahlenther Onkol. Nov;184(11):572-9. Epub 2008 Nov 19
  • Möller I, Michel K, Frech N, Burger M, Pfeifer D, Frommolt P, Veelken H, Thomas- Kaskel AK (2008). Dendritic cell maturation with poly(I:C)-based versus PGE2-based cytokine combinations results in differential functional characteristics relevant to clinical application. J Immunother. Jun;31(5):506
  • Müller-Ehmsen J, Braun D, Schneider T, Pfister R, Worm N, Wielckens K, Scheid C, Frommolt P, Flesch M (2008). Decreased number of circulating progenitor cells in obesity: beneficial effects of weight reduction. Eur Heart J. Jun;29(12):1560-8. Epub 2008 May 30
  • Tossios P, Krausgrill B, Schmidt M, Fischer T, Halbach M, Fries JW, Fahnenstich S, Frommolt P, Heppelmann I, Schmidt A, Schomäcker K, Fischer JH, Bloch W, Mehlhorn U, Schwinger RH, Müller- Ehmsen J (2008). Role of balloon occlusion for mononuclear bone marrow cell deposition after intracoronary injection in pigs with reperfused myocardial infarction. Eur Heart J. Aug;29(15):1911-21. Epub 2008 Jun 10

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Michael Hallek

  • Büning H, Perabo L, Coutelle O, Quadt-Humme S, Hallek M (2008). Recent developments in adeno-associated virus vector technology. J Gene Med. Jul;10(7):717-33. Review
  • Elter T, Molnar I, Kuhlmann J, Hallek M, Wendtner C (2008). Pharmacokinetics of alemtuzumab and the relevance in clinical practice. Leuk Lymphoma. Dec;49(12):2256-62. Review
  • Forster K, Obermeier A, Mitina O, Simon N, Warmuth M, Krause G, Hallek M (2008). Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells. Ann Hematol. Mar;87(3):183-93. Epub 2007 Oct 25
  • Jelkmann W, Bohlius J, Hallek M, Sytkowski AJ (2008). The erythropoietin receptor in normal and cancer tissues. Crit Rev Oncol Hematol. Jul;67(1):39-61. Epub 2008 Apr 23. Review
  • Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ (2008). International Workshop on Chronic Lymphocytic Leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. Jun 15;111(12):5446-56. Epub 2008 Jan 23. Erratum in: Blood. 2008 Dec 15;112(13):5259
  • Kronenberger K, Nössner E, Frankenberger B, Wahl U, Dreyling M, Hallek M, Mocikat R (2008). A polyvalent cellular vaccine induces T-cell responses against specific self-antigens overexpressed in chronic lymphocytic B-cell leukemia. J Immunother. Oct;31(8):723-30
  • Ostgathe C, Walshe R, Wolf J, Hallek M, Voltz R (2008). A cost calculation model for specialist palliative care for patients with non-small cell lung cancer in a tertiary centre. Support Care Cancer. May;16(5):501-6. Epub 2007 Oct 2
  • Pallasch CP, Schulz A, Kutsch N, Schwamb J, Hagist S, Kashkar H, Ultsch A, Wickenhauser C, Hallek M, Wendtner CM (2008). Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease. Blood. Nov 15;112(10):4213-9. Epub 2008 Aug 15
  • Perabo L, Huber A, Märsch S, Hallek M, Büning H (2008). Artificial evolution with adeno-associated viral libraries. Comb Chem High Throughput Screen. Feb;11(2):118-26. Review
  • Ritgen M, Böttcher S, Stilgenbauer S, Bunjes D, Schubert J, Cohen S, Humpe A, Hallek M, Kneba M, Schmitz N, Döhner H, Dreger P (2008). German CLL Study Group. Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial. Leukemia. Jul;22(7):1377-86. Epub 2008 Apr 17
  • Rüping MJ, Albermann N, Ebinger F, Burckhardt I, Beisel C, Müller C, Vehreschild JJ, Kochanek M, Fätkenheuer G, Bangard C, Ullmann AJ, Herr W, Kolbe K, Hallek M, Cornely OA (2008). Posaconazole concentrations in the central nervous system. J Antimicrob Chemother. Dec;62(6):1468-70. Epub 2008 Sep 28
  • Schnell R, Dietlein M, Schomäcker K, Kobe C, Borchmann P, Schicha H, Hallek M, Engert A (2008). Yttrium-90 ibritumomab tiuxetan-induced complete remission in a patient with classical lymphocyte-rich Hodgkin's Lymphoma. Onkologie. Feb;31(1-2):49-51. Epub 2008 Jan 22
  • Schweighofer CD, Hallek M, Wendtner CM (2008). Eradication of minimal residual disease in chronic lymphocytic leukemia. Curr Hematol Malig Rep. Jan;3(1):54-60. Review
  • Veldurthy A, Patz M, Hagist S, Pallasch CP, Wendtner CM, Hallek M, Krause G (2008). The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes. Blood. Aug 15;112(4):1443-52. Epub 2008 Jun 12
  • Zuber C, Mitteregger G, Schuhmann N, Rey C, Knackmuss S, Rupprecht W, Reusch U, Pace C, Little M, Kretzschmar HA, Hallek M, Büning H, Weiss S (2008). Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. J Gen Virol. Aug;89(Pt 8):2055-61

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Matthias Hammerschmidt

  • Hammerschmidt M, Wedlich D (2008). Regulated adhesion as a driving force of gastrulation movements. Development. Nov;135(22):3625-41. Review
  • Laue K, Daujat S, Crump JG, Plaster N, Roehl HH, Tübingen 2000 Screen Consortium, Kimmel CB, Schneider R, Hammerschmidt M (2008). The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development. Jun;135(11):1935-46
  • Laue K, Jänicke M, Plaster N, Sonntag C, Hammerschmidt M (2008). Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development. Development. Nov;135(22):3775-87. Epub 2008 Oct 16
  • Lengerke C, Schmitt S, Bowman TV, Jang IH, Maouche-Chretien L, McKinney-Freeman S, Davidson AJ, Hammerschmidt M, Rentzsch F, Green JB, Zon LI, Daley GQ (2008). BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell Stem Cell. Jan 10;2(1):72-82
  • Smith KA, Chocron S, von der Hardt S, de Pater E, Soufan A, Bussmann J, Schulte-Merker S, Hammerschmidt M, Bakkers J (2008). Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev Cell. Feb;14(2):287-97
  • Zhang JL, Qiu LY, Kotzsch A, Weidauer S, Patterson L, Hammerschmidt M, Sebald W, Mueller TD (2008). Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. Dev Cell. May;14(5):739-50

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Hans Christian Hennies

  • Hennies HC, Kornak U, Zhang H, Egerer J, Zhang X, Seifert W, Kühnisch J, Budde B, Nätebus M, Brancati F, Wilcox WR, Müller D, Kaplan PB, Rajab A, Zampino G, Fodale V, Dallapiccola B, Newman W, Metcalfe K, Clayton-Smith J, Tassabehji M, Steinmann B, Barr FA, Nürnberg P, Wieacker P, Mundlos S (2008). Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. Nat Genet. Dec;40(12):1410-2. Epub 2008 Nov 9
  • Hillmer AM, Flaquer A, Hanneken S, Eigelshoven S, Kortüm AK, Brockschmidt FF, Golla A, Metzen C, Thiele H, Kolberg S, Reinartz R, Betz RC, Ruzicka T, Hennies HC, Kruse R, Nöthen MM (2008). Genome-wide scan and fine-mapping linkage study of androgenetic alopecia reveals a locus on chromosome 3q26. Am J Hum Genet. Mar;82(3):737-43. Epub 2008 Feb 21
  • Lugassy J, Hennies HC, Indelman M, Khamaysi Z, Bergman R, Sprecher E (2008). Rapid detection of homozygous mutations in congenital recessive ichthyosis. Arch Dermatol Res. Feb;300(2):81-5. Epub 2007 Nov 22

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Marco Herling

  • Herling M, Patel KA, Teitell MA, Konopleva M, Ravandi F, Kobayashi R, Jones D (2008). High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. Blood. Jan 1;111(1):328-37

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Thorsten Hoppe

  • Kim J, Löwe T, Hoppe T (2008). Protein quality control gets muscle into shape. Trends Cell Biol. 18264-72
  • Mouysset J, Deichsel A, Moser S, Hoege C, Hyman AA, Gartner A, Hoppe T (2008). Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication. Proc Natl Acad Sci. 105, 12879-84

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Hamid Kashkar

  • Pallasch CP, Schulz A, Kutsch N, Schwamb J, Hagist S, Kashkar H, Ultsch A, Wickenhauser C, Hallek M, Wendtner CM (2008). Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease. Blood. Nov 15;112(10):4213-9. Epub 2008 Aug 15

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Peter Kloppenburg

  • Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC (2008). PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response. Cell Metab. Apr;7(4):291-301
  • Husch A, Hess S, Kloppenburg P (2008). Functional parameters of voltage-activated Ca2+ currents from olfactory interneurons in the antennal lobe of Periplaneta americana. J Neurophysiol. Jan;99(1):320-32. Epub 2007 Nov 14
  • Kloppenburg P, Mercer AR (2008). Serotonin modulation of moth central olfactory neurons. Annu Rev Entomol. 2008;53:179-90. Review

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Thomas Krieg

  • Downey JM, Krieg T, Cohen MV (2008). Mapping preconditioning's signaling pathways: an engineering approach. Ann N Y Acad Sci. Mar;1123:187-96
  • Eming S, Smola H, Hartmann B, Malchau G, Wegner R, Krieg T, Smola-Hess S (2008). The inhibition of matrix metalloproteinase activity in chronic wounds by a polyacrylate superabsorber. Biomaterials. Jul;29(19):2932-40. Epub 2008 Apr 9
  • Eren M, Fabri M, Krieg T, Eming SA (2008). Pustulosis acuta generalisata with joint involvement in an HLA-A2- and HLA-B35-positive patient. J Am Acad Dermatol. Jun;58(6):1056-8. Epub 2008 Apr 8
  • Fabri M, Hunzelmann N, Krieg T, Rubbert A (2008). Discordant response to rituximab in a systemic sclerosis patient with associated myositis. J Am Acad Dermatol. May;58(5 Suppl 1):S127-8
  • Riad A, Bien S, Gratz M, Escher F, Westermann D, Heimesaat MM, Bereswill S, Krieg T, Felix SB, Schultheiss HP, Kroemer HK, Tschöpe C (2008). Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. Eur J Heart Fail. Mar;10(3):233-43. Epub 2008 Mar 5
  • Scholten J, Hartmann K, Gerbaulet A, Krieg T, Müller W, Testa G, Roers A (2008). Mast cell-specific Cre/loxP-mediated recombination in vivo. Transgenic Res. Apr;17(2):307-15. Epub 2007 Oct 31
  • Schuster J, Tantcheva-Poor I, Wickenhauser C, Chemnitz JM, Hunzelmann N, Krieg T, Hartmann K (2008). African tick bite fever--papulovesicular exanthem with fever after staying in South Africa. J Dtsch Dermatol Ges. May;6(5):379-81. Epub 2007 Nov 14. English, German
  • Tissier R, Berdeaux A, Ghaleh B, Couvreur N, Krieg T, Cohen MV, Downey JM (2008). Making the heart resistant to infarction: how can we further decrease infarct size? Front Biosci. Jan 1;13:284-301. Review
  • Wenzel J, Peters B, Zahn S, Birth M, Hofmann K, Küsters D, Tomiuk S, Baron JM, Merk HF, Mauch C, Krieg T, Bieber T, Tüting T, Bosio A (2008). Gene expression profiling of lichen planus reflects CXCL9+-mediated inflammation and distinguishes this disease from atopic dermatitis and psoriasis. J Invest Dermatol. Jan;128(1):67-78. Epub 2007 Aug 16
  • Wenzel J, Tomiuk S, Zahn S, Küsters D, Vahsen A, Wiechert A, Mikus S, Birth M, Scheler M, von Bubnoff D, Baron JM, Merk HF, Mauch C, Krieg T, Bieber T, Bosio A, Hofmann K, Tüting T, Peters B (2008). Transcriptional profiling identifies an interferon-associated host immune response in invasive squamous cell carcinoma of the skin. Int J Cancer. Dec 1;123(11):2605-15
  • Woodall BP, Nyström A, Iozzo RA, Eble JA, Niland S, Krieg T, Eckes B, Pozzi A, Iozzo RV (2008). Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity. J Biol Chem. Jan 25;283(4):2335-43. Epub 2007 Nov 15

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Wilhelm Krone

  • Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M (2008). IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J Neurochem. Nov;107(4):907-17. Epub 2008 Sep 18
  • Gouni-Berthold I, Berthold HK, Gylling H, Hallikainen M, Giannakidou E, Stier S, Ko Y, Patel D, Soutar AK, Seedorf U, Mantzoros CS, Plat J, Krone W (2008). Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men. Atherosclerosis. May;198(1):198-207. Epub 2007 Nov 5
  • Gouni-Berthold I, Berthold HK, Chamberland JP, Krone W, Mantzoros CS (2008). Short-term treatment with ezetimibe, simvastatin or their combination does not alter circulating adiponectin, resistin or leptin levels in healthy men. Clin Endocrinol (Oxf). Apr;68(4):536-41. Epub 2007 Oct 31
  • Gouni-Berthold I, Berthold HK, Mantzoros CS, Böhm M, Krone W (2008). Sex disparities in the treatment and control of cardiovascular risk factors in type 2 diabetes. Diabetes Care. Jul;31(7):1389-91. Epub 2008 Mar 28
  • Klöting N, Koch L, Wunderlich T, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M (2008). Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth. Diabetes. Aug;57(8):2074-82. Epub 2008 Apr 28
  • Laudes M, Bilkovski R, Oberhauser F, Droste A, Gomolka M, Leeser U, Udelhoven M, Krone W (2008). Transcription factor FBI-1 acts as a dual regulator in adipogenesis by coordinated regulation of cyclin-A and E2F-4. J Mol Med (Berl). May;86(5):597-608. Epub 2008 Mar 27

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Martin Krönke

  • Bohne F, Chmielewski M, Ebert G, Wiegmann K, Kürschner T, Schulze A, Urban S, Krönke M, Abken H, Protzer U (2008). T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes. Gastroenterology. Jan;134(1):239-47. Epub 2007 Nov 4
  • Chung YS, Sabel K, Krönke M, Klimka A (2008). Gene transfer of Hodgkin cell lines via multivalent anti-CD30 scFv displaying bacteriophage. BMC Mol Biol. Apr 16;9:37
  • Krönke M (2008). Innate immunity. Immunobiology. 2008;213(3-4):159. Epub 2008 Feb 20
  • Popov A, Driesen J, Abdullah Z, Wickenhauser C, Beyer M, Debey-Pascher S, Saric T, Kummer S, Takikawa O, Domann E, Chakraborty T, Krönke M, Utermöhlen O, Schultze JL (2008). Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J Immunol. Oct 1;181(7):4976-88
  • Schramm M, Herz J, Haas A, Krönke M, Utermöhlen O (2008). Acid sphingomyelinase is required for efficient phago-lysosomal fusion. Cell Microbiol. Sep;10(9):1839-53. Epub 2008 May 13
  • Utermöhlen O, Herz J, Schramm M, Krönke M (2008). Fusogenicity of membranes: the impact of acid sphingomyelinase on innate immune responses. Immunobiology. 2008;213(3-4):307-14. Epub 2007 Dec 31. Review

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Christian Kubisch

  • Boulouiz R, Li Y, Soualhine H, Abidi O, Chafik A, Nürnberg G, Becker C, Nürnberg P, Kubisch C, Wollnik B, Barakat A (2008). A novel mutation in the Espin gene causes autosomal recessive nonsyndromic hearing loss but no apparent vestibular dysfunction in a Moroccan family. Am J Med Genet A. Dec 1;146A(23):3086-9
  • Netzer C, Freudenberg J, Heinze A, Heinze-Kuhn K, Goebel I, McCarthy LC, Roses AD, Göbel H, Todt U, Kubisch C (2008). Replication study of the insulin receptor gene in migraine with aura. Genomics. Jun;91(6):503-7. Epub 2008 May 2
  • Netzer C, Freudenberg J, Toliat MR, Heinze A, Heinze-Kuhn K, Thiele H, Goebel I, Nürnberg P, Ptácek LJ, Göbel H, Todt U, Kubisch C (2008). Genetic association studies of the chromosome 15 GABA-A receptor cluster in migraine with aura.Am J Med Genet B Neuropsychiatr Genet. Jan 5;147B(1):37-41
  • Nyholt DR, LaForge KS, Kallela M, Alakurtti K, Anttila V, Färkkilä M, Hämaläinen E, Kaprio J, Kaunisto MA, Heath AC, Montgomery GW, Göbel H, Todt U, Ferrari MD, Launer LJ, Frants RR, Terwindt GM, de Vries B, Verschuren WM, Brand J, Freilinger T, Pfaffenrath V, Straube A, Ballinger DG, Zhan Y, Daly MJ, Cox DR, Dichgans M, van den Maagdenberg AM, Kubisch C, Martin NG, Wessman M, Peltonen L, Palotie A (2008). A high-density association screen of 155 ion transport genes for involvement with common migraine. Hum Mol Genet. Nov 1;17(21):3318-31. Epub 2008 Aug 2
  • Sajjad N, Goebel I, Kakar N, Cheema AM, Kubisch C, Ahmad J (2008). A novel HSF4 gene mutation (p.R405X) causing autosomal recessive congenital cataracts in a large consanguineous family from Pakistan. BMC Med Genet. Nov 11;9:99

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Tobias Lamkemeyer

  • Duechting A, Tschöpe C, Kaiser H, Lamkemeyer T, Tanaka N, Aberle S, Lang F, Torresi J, Kandolf R, Bock CT (2008). Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells. J Virol. Aug;82(16):7942-52. Epub 2008 Jun 11
  • Hála M, Cole R, Synek L, Drdová E, Pecenková T, Nordheim A, Lamkemeyer T, Madlung J, Hochholdinger F, Fowler JE, Zárský V (2008). An exocyst complex functions in plant cell growth in Arabidopsis and tobacco. Plant Cell. May;20(5):1330-45. Epub 2008 May 20
  • Hoecker N, Lamkemeyer T, Sarholz B, Paschold A, Fladerer C, Madlung J, Wurster K, Stahl M, Piepho HP, Nordheim A, Hochholdinger F (2008). Analysis of nonadditive protein accumulation in young primary roots of a maize (Zea mays L.) F(1)-hybrid compared to its parental inbred lines. Proteomics. Sep;8(18):3882-94
  • Meyer VS, Kastenmuller W, Gasteiger G, Franz-Wachtel M, Lamkemeyer T, Rammensee HG, Stevanovic S, Sigurdardottir D, Drexler I (2008). Long-term immunity against actual poxviral HLA ligands as identified by differential stable isotope labeling. J Immunol. Nov 1;181(9):6371-83

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Michael Lammers

  • Lammers M, Meyer S, Kühlmann D, Wittinghofer A (2008). Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem. Dec 12;283(50):35236-46. Epub 2008 Sep 30

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Thomas Langer

  • Merkwirth C, Dargazanli S, Tatsuta T, Geimer S, Löwer B, Wunderlich FT, von Kleist-Retzow JC, Waisman A, Westermann B, Langer T (2008). Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev. Feb 15;22(4):476-88
  • Merkwirth C, Langer T (2008). Mitofusin 2 builds a bridge between ER and mitochondria. Cell. Dec 26;135(7):1165-7
  • Tatsuta T, Langer T (2008). Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J. Jan 23;27(2):306-14. Review

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Nils-Göran Larsson

  • Bruton JD, Place N, Yamada T, Silva JP, Andrade FH, Dahlstedt AJ, Zhang SJ, Katz A, Larsson NG, Westerblad H (2008). Reactive oxygen species and fatigue-induced prolonged low-frequency force depression in skeletal muscle fibres of rats, mice and SOD2 overexpressing mice. J Physiol. Jan 1;586(1):175-84. Epub 2007 Nov 15
  • Dufour E, Terzioglu M, Sterky FH, Sörensen L, Galter D, Olson L, Wilbertz J, Larsson NG (2008). Age-associated mosaic respiratory chain deficiency causes trans-neuronal degeneration. Hum Mol Genet. May 15;17(10):1418-26. Epub 2008 Feb 1
  • Sterky FH, Larsson NG (2008). Complex I: a complex gateway to the powerhouse. Cell Metab. Apr;7(4):278-9
  • Stewart JB, Freyer C, Elson JL, Larsson NG (2008). Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease. Nat Rev Genet. Sep;9(9):657-62
  • Stewart JB, Freyer C, Elson JL, Wredenberg A, Cansu Z, Trifunovic A, Larsson NG (2008). Strong purifying selection in transmission of mammalian mitochondrial DNA. PLoS Biol. Jan;6(1):e10

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Ivan Matic

  • Matic I, Macek B, Hilger M, Walther TC, Mann M (2008). Phosphorylation of SUMO-1 occurs in vivo and is conserved through evolution. Journal of proteome research. 2008, 7, (9), 4050-7
  • Matic I, van Hagen M, Schimmel J, Macek B, Ogg SC, Tatham MH, Hay RT, Lamond AI, Mann M, Vertegaal AC (2008). In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy. Molecular & Cellular Proteomics. 2008, 7, (1), 132-44
  • Schimmel J, Larsen KM, Matic I, van Hagen M, Cox J, Mann M, Andersen JS, Vertegaal AC (2008). The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle. Molecular & Cellular Proteomics. 2008, 7, (11), 2107-22

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Roman-Ulrich Müller

  • Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Müller RU, Straka E, Su L, Burki EA, Crowell RE, Patel R, Kulkarni T, Homer R, Zelterman D, Kidd KK, Zhu Y, Christiani DC, Belinsky SA, Slack FJ, Weidhaas JB (2008). A SNP in a let-7 microRNA Complementary Site in the KRAS 3’ Untranslated Region Increases Non-Small Cell Lung Cancer Risk. Cancer Res. Oct

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Carien M. Niessen

  • Ferber EC, Kajita M, Wadlow A, Tobiansky L, Niessen C, Ariga H, Daniel J, Fujita Y (2008). A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus. J Biol Chem. May 9;283(19):12691-700. Epub 2008 Mar 19
  • Niessen CM, Gottardi CJ (2008). Molecular components of the adherens junction. Biochim Biophys Acta. Mar;1778(3):562-71. Epub 2008 Jan 14. Review
  • Stachelscheid H, Ibrahim H, Koch L, Schmitz A, Tscharntke M, Wunderlich FT, Scott J, Michels C, Wickenhauser C, Haase I, Brüning JC, Niessen CM (2008). Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation. EMBO J. Aug 6;27(15):2091-101. Epub 2008 Jul 24

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Angelika A. Noegel

  • Joseph JM, Fey P, Ramalingam N, Liu XI, Rohlfs M, Noegel AA, Müller-Taubenberger A, Glöckner G, Schleicher M (2008). The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms. PLoS One. Jul 9;3(7):e2654
  • Lu W, Gotzmann J, Sironi L, Jaeger VM, Schneider M, Lüke Y, Uhlén M, Szigyarto CA, Brachner A, Ellenberg J, Foisner R, Noegel AA, Karakesisoglou I (2008). Sun1 forms immobile macromolecular assemblies at the nuclear envelope. Biochim Biophys Acta. Dec;1783(12):2415-26. Epub 2008 Sep 19
  • Lüke Y, Zaim H, Karakesisoglou I, Jaeger VM, Sellin L, Lu W, Schneider M, Neumann S, Beijer A, Munck M, Padmakumar VC, Gloy J, Walz G, Noegel AA (2008). Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci. Jun 1;121(Pt 11):1887-98. Epub 2008 May 13
  • Mondal S, Bakthavatsalam D, Steimle P, Gassen B, Rivero F, Noegel AA (2008). Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions. J Cell Biol. Jun 2;181(5):747-60. Epub 2008 May 26
  • Schneider M, Noegel AA, Karakesisoglou I (2008). KASH-domain proteins and the cytoskeletal landscapes of the nuclear envelope. Biochem Soc Trans. Dec;36(Pt 6):1368-72
  • Shina MC, Noegel AA (2008). Invertebrate coronins. Subcell Biochem. 48:88-97. Review
  • Xiong H, Rivero F, Euteneuer U, Mondal S, Mana-Capelli S, Larochelle D, Vogel A, Gassen B, Noegel AA (2008). Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability. Traffic. May;9(5):708-24. Epub 2008 Feb 11

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Peter Nürnberg

  • Bergmann C, Fliegauf M, Brüchle NO, Frank V, Olbrich H, Kirschner J, Schermer B, Schmedding I, Kispert A, Kränzlin B, Nürnberg G, Becker C, Grimm T, Girschick G, Lynch SA, Kelehan P, Senderek J, Neuhaus TJ, Stallmach T, Zentgraf H, Nürnberg P, Gretz N, Lo C, Lienkamp S, Schäfer T, Walz G, Benzing T, Zerres K, Omran H (2008). Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Am J Hum Genet. Apr;82(4):959-70. Epub 2008 Mar 27
  • Boulouiz R, Li Y, Soualhine H, Abidi O, Chafik A, Nürnberg G, Becker C, Nürnberg P, Kubisch C, Wollnik B, Barakat A (2008). A novel mutation in the Espin gene causes autosomal recessive nonsyndromic hearing loss but no apparent vestibular dysfunction in a Moroccan family. Am J Med Genet A. Dec 1;146A(23):3086-9
  • Budde BS, Namavar Y, Barth PG, Poll-The BT, Nürnberg G, Becker C, van Ruissen F, Weterman MA, Fluiter K, te Beek ET, Aronica E, van der Knaap MS, Höhne W, Toliat MR, Crow YJ, Steinling M, Voit T, Roelenso F, Brussel W, Brockmann K, Kyllerman M, Boltshauser E, Hammersen G, Willemsen M, Basel-Vanagaite L, Krägeloh-Mann I, de Vries LS, Sztriha L, Muntoni F, Ferrie CD, Battini R, Hennekam RC, Grillo E, Beemer FA, Stoets LM, Wollnik B, Nürnberg P, Baas F (2008). tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia. Nat Genet. Sep;40(9):1113-8
  • Frank V, den Hollander AI, Brüchle NO, Zonneveld MN, Nürnberg G, Becker C, Du Bois G, Kendziorra H, Roosing S, Senderek J, Nürnberg P, Cremers FP, Zerres K, Bergmann C (2008). Mutations of the CEP290 gene encoding a centrosomal protein cause Meckel-Gruber syndrome. Hum Mutat. Jan;29(1):45-52
  • Franke A, Fischer A, Nothnagel M, Becker C, Grabe N, Till A, Lu T, Müller-Quernheim J, Wittig M, Hermann A, Balschun T, Hofmann S, Niemiec R, Schulz S, Hampe J, Nikolaus S, Nürnberg P, Krawczak M, Schürmann M, Rosenstiel P, Nebel A, Schreiber S (2008). Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2. Gastroenterology. Oct;135(4):1207-15. Epub 2008 Jul 18
  • Geier C, Gehmlich K, Ehler E, Hassfeld S, Perrot A, Hayess K, Cardim N, Wenzel K, Erdmann B, Krackhardt F, Posch MG, Osterziel KJ, Bublak A, Nägele H, Scheffold T, Dietz R, Chien KR, Spuler S, Fürst DO, Nürnberg P, Ozcelik C (2008). Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. Hum Mol Genet. Sep 15;17(18):2753-65. Epub 2008 May 27. Erratum in: Hum Mol Genet. 2008 Nov 1;17(21):3436
  • Hennies HC, Kornak U, Zhang H, Egerer J, Zhang X, Seifert W, Kühnisch J, Budde B, Nätebus M, Brancati F, Wilcox WR, Müller D, Kaplan PB, Rajab A, Zampino G, Fodale V, Dallapiccola B, Newman W, Metcalfe K, Clayton-Smith J, Tassabehji M, Steinmann B, Barr FA, Nürnberg P, Wieacker P, Mundlos S (2008). Gerodermia osteodysplastica is caused by mutations in SCYL1BP1, a Rab-6 interacting golgin. Nat Genet. Dec;40(12):1410-2. Epub 2008 Nov 9
  • Huyghe JR, Van Laer L, Hendrickx JJ, Fransen E, Demeester K, Topsakal V, Kunst S, Manninen M, Jensen M, Bonaconsa A, Mazzoli M, Baur M, Hannula S, Mäki-Torkko E, Espeso A, Van Eyken E, Flaquer A, Becker C, Stephens D, Sorri M, Orzan E, Bille M, Parving A, Pyykkö I, Cremers CW, Kremer H, Van de Heyning PH, Wienker TF, Nürnberg P, Pfister M, Van Camp G (2008). Genome-wide SNP-based linkage scan identifies a locus on 8q24 for an age-related hearing impairment trait. Am J Hum Genet. Sep;83(3):401-7. Epub 2008 Aug 28
  • Janke D, Mehralivand S, Strand D, Gödtel-Armbrust U, Habermeier A, Gradhand U, Fischer C, Toliat MR, Fritz P, Zanger UM, Schwab M, Fromm MF, Nürnberg P, Wojnowski L, Closs EI, Lang T (2008). 6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4. Hum Mutat. May;29(5):659-69
  • Kayser M, Lao O, Saar K, Brauer S, Wang X, Nürnberg P, Trent RJ, Stoneking M (2008). Genome-wide analysis indicates more Asian than Melanesian ancestry of Polynesians. Am J Hum Genet. Jan;82(1):194-8
  • Kloeckener-Gruissem B, Vandekerckhove K, Nürnberg G, Neidhardt J, Zeitz C, Nürnberg P, Schipper I, Berger W (2008). Mutation of solute carrier SLC16A12 associates with a syndrome combining juvenile cataract with microcornea and renal glucosuria. Am J Hum Genet. Mar;82(3):772-9. Epub 2008 Feb 14
  • Kornak U, Reynders E, Dimopoulou A, van Reeuwijk J, Fischer B, Rajab A, Budde B, Nürnberg P, Foulquier F, ARCL Debré-type Study Group, Lefeber D, Urban Z, Gruenewald S, Annaert W, Brunner HG, van Bokhoven H, Wevers R, Morava E, Matthijs G, Van Maldergem L, Mundlos S (2008). Impaired glycosylation and cutis laxa caused by mutations in the vesicular H+-ATPase subunit ATP6V0A2. Nat Genet. Jan;40(1):32-4. Epub 2007 Dec 23
  • Kuhl A, Melberg A, Meinl E, Nürnberg G, Nürnberg P, Kehrer-Sawatzki H, Jenne DE (2008). Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: corroboration and narrowing of the critical region on 10q22.3. Eur J Hum Genet. Mar;16(3):367-73. Epub 2008 Jan 16
  • Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M (2008). Correlation between genetic and geographic structure in Europe. Curr Biol. Aug 26;18(16):1241-8. Epub 2008 Aug 7
  • Neidhardt J, Glaus E, Lorenz B, Netzer C, Li Y, Schambeck M, Wittmer M, Feil S, Kirschner-Schwabe R, Rosenberg T, Cremers FP, Bergen AA, Barthelmes D, Baraki H, Schmid F, Tanner G, Fleischhauer J, Orth U, Becker C, Wegscheider E, Nürnberg G, Nürnberg P, Bolz HJ, Gal A, Berger W (2008). Identification of novel mutations in X-linked retinitis pigmentosa families and implications for diagnostic testing. Mol Vis. Jun 6;14:1081-93
  • Netzer C, Freudenberg J, Toliat MR, Heinze A, Heinze-Kuhn K, Thiele H, Goebel I, Nürnberg P, Ptácek LJ, Göbel H, Todt U, Kubisch C (2008). Genetic association studies of the chromosome 15 GABA-A receptor cluster in migraine with aura. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 5;147B(1):37-41
  • Märschenz S, Brinckmann A, Nürnberg P, Krüger DH, Günther S, Meisel H (2008). Co-replication analyses of naturally occurring defective hepatitis B virus variants with wild-type. Virology. Mar 15;372(2):247-59. Epub 2007 Dec 3
  • Nürnberg G, Jacobi FK, Broghammer M, Becker C, Blin N, Nürnberg P, Stephani U, Pusch CM (2008). Refinement of the MYP3 locus on human chromosome 12 in a German family with Mendelian autosomal dominant high-grade myopia by SNP array mapping. Int J Mol Med. Apr;21(4):429-38
  • Pasternack SM, von Kügelgen I, Aboud KA, Lee YA, Rüschendorf F, Voss K, Hillmer AM, Molderings GJ, Franz T, Ramirez A, Nürnberg P, Nöthen MM, Betz RC (2008). G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. Nat Genet. Mar;40(3):329-34. Epub 2008 Feb 24
  • Puk O, Löster J, Dalke C, Soewarto D, Fuchs H, Budde B, Nürnberg P, Wolf E, de Angelis MH, Graw J (2008). Mutation in a novel connexin-like gene (Gjf1) in the mouse affects early lens development and causes a variable small-eye phenotype. Invest Ophthalmol Vis Sci. Apr;49(4):1525-32
  • Rutsch F, Böyer P, Nitschke Y, Ruf N, Lorenz-Depierieux B, Wittkampf T, Weissen-Plenz G, Fischer RJ, Mughal Z, Gregory JW, Davies JH, Loirat C, Strom TM, Schnabel D, Nürnberg P, Terkeltaub R, GACI Study Group (2008). Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy. Circ Cardiovasc Genet. Dec;1(2):133-40
  • Sanggaard KM, Kjaer KW, Eiberg H, Nürnberg G, Nürnberg P, Hoffman K, Jensen H, Sørum C, Rendtorff ND, Tranebjaerg L (2008). A novel nonsense mutation in MYO6 is associated with progressive nonsyndromic hearing loss in a Danish DFNA22 family. Am J Med Genet A. Apr 15;146A(8):1017-25

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Linda Partridge

  • Alic N, Partridge L (2008). Stage debut for the elusive Drosophila insulin-like growth factor binding protein. J Biol. Jul 7;7(6):18. Review
  • Barnes AI, Wigby S, Boone JM, Partridge L, Chapman T (2008). Feeding, fecundity and lifespan in female Drosophila melanogaster. Proc Biol Sci. Jul 22;275(1643):1675-83
  • Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L (2008). Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PLoS One. ;3(11):e3721. Epub 2008 Nov 13
  • Butler RN, Miller RA, Perry D, Carnes BA, Williams TF, Cassel C, Brody J, Bernard MA, Partridge L, Kirkwood T, Martin GM, Olshansky SJ (2008). New model of health promotion and disease prevention for the 21st century. BMJ. Jul 8;337:a399. doi: 10.1136/bmj.a399
  • Gems D, Partridge L (2008). Stress-response hormesis and aging: "that which does not kill us makes us stronger". Cell Metab. Mar;7(3):200-3. Review
  • Giannakou ME, Goss M, Partridge L (2008). Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. Aging Cell. Mar;7(2):187-98. Epub 2008 Jan 30
  • Milton CC, Partridge L (2008). Brief carbon dioxide exposure blocks heat hardening but not cold acclimation in Drosophila melanogaster. J Insect Physiol. Jan;54(1):32-40. Epub 2007 Aug 10
  • Murphy MP, Partridge L (2008). Toward a control theory analysis of aging. Annu Rev Biochem. ;77:777-98. Review
  • Partridge L (2008). Some highlights of research on aging with invertebrates, 2008. Aging Cell. Oct;7(5):605-8. Epub 2008 Jul 31. Review
  • Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, Thornton JM, Gems D, Partridge L, Withers DJ (2008). Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J. Mar;22(3):807-18. Epub 2007 Oct 10
  • Selman C, Lingard S, Gems D, Partridge L, Withers DJ (2008). Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis". Science. May 23;320(5879):1012; author reply 1012
  • Wong R, Piper MD, Blanc E, Partridge L (2008). Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster. Nat Methods. Mar;5(3):214-5; author reply 215

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Manolis Pasparakis

  • Ermolaeva MA, Michallet MC, Papadopoulou N, Utermöhlen O, Kranidioti K, Kollias G, Tschopp J, Pasparakis M (2008). Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol. 2008, 9(9):1037-46
  • Gareus R, Kotsaki E, Xanthoulea S, van der Made I, Gijbels MJ, Kardakaris R, Polykratis A, Kollias G, de Winther MP, Pasparakis M (2008). Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis. Cell Metab. 2008, 8(5):372-83
  • Heinrichsdorff J, Luedde T, Perdiguero E, Nebreda AR, Pasparakis M (2008). p38alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure. EMBO Rep. 2008, 9(10):1048-54
  • Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, Slutsky AS, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM (2008). Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell. 2008, 133(2):235-49
  • Julius C, Heikenwalder M, Schwarz P, Marcel A, Karin M, Prinz M, Pasparakis M, Aguzzi A (2008). Prion propagation in mice lacking central nervous system NF-κB signalling. J Gen Virol. 2008, 89(Pt 6):1545-50
  • Luedde T, Heinrichsdorff J, de Lorenzi R, De Vos R, Roskams T, Pasparakis M (2008). IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver. Proc Natl Acad Sci U S A. 2008, 105(28):9733-8
  • Michallet MC, Meylan E, Ermolaeva MA, Vazquez J, Rebsamen M, Curran J, Poeck H, Bscheider M, Hartmann G, König M, Kalinke U, Pasparakis M, Tschopp J (2008). TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway. Immunity. 2008, 28(5):651-61
  • Otero JE, Dai S, Foglia D, Alhawagri M, Vacher J, Pasparakis M, Abu-Amer Y (2008). Defective osteoclastogenesis by IKKbeta-null precursors is a result of RANKL-induced JNK-dependent apoptosis and impaired differentiation. J Biol Chem. 2008, 283(36):24546-53
  • Otipoby KL, Sasaki Y, Schmidt-Supprian M, Patke A, Gareus R, Pasparakis M, Tarakhovsky A, Rajewsky K (2008). BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells. Proc Natl Acad Sci U S A. 2008, 105(34):12435-8
  • Pasparakis M (2008). IKK/NF-kappaB signaling in intestinal epithelial cells controls immune homeostasis in the gut. Mucosal Immunol. 2008, 1 Suppl 1:S54-7
  • Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC (2008). Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A. 2008, 105(4):1297-302

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Mats Paulsson

  • Blumbach K, Niehoff A, Paulsson M, Zaucke F (2008). Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture. Matrix Biol. May;27(4):306-18. Epub 2007 Dec 3
  • Gara SK, Grumati P, Urciuolo A, Bonaldo P, Kobbe B, Koch M, Paulsson M, Wagener R (2008). Three novel collagen VI chains with high homology to the alpha3 chain. J Biol Chem. Apr 18;283(16):10658-70. Epub 2008 Feb 13
  • Gebauer JM, Müller S, Hanisch FG, Paulsson M, Wagener R (2008). O-glucosylation and O-fucosylation occur together in close proximity on the first epidermal growth factor repeat of AMACO (VWA2 protein). J Biol Chem. Jun 27;283(26):17846-54. Epub 2008 Apr 23
  • Grimm-Günter EM, Milbrandt M, Merkl B, Paulsson M, Plomann M (2008). PACSIN proteins bind tubulin and promote microtubule assembly. Exp Cell Res. Jun 10;314(10):1991-2003. Epub 2008 Mar 29
  • Kalkhof S, Haehn S, Ihling C, Paulsson M, Smyth N, Sinz A (2008). Determination of disulfide bond patterns in laminin beta1 chain N-terminal domains by nano-high-performance liquid chromatography/matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry. Rapid Commun Mass Spectrom. Jun;22(12):1933-40
  • Maier S, Paulsson M, Hartmann U (2008). The widely expressed extracellular matrix protein SMOC-2 promotes keratinocyte attachment and migration. Exp Cell Res. Aug 1;314(13):2477-87. Epub 2008 Jun 7
  • Schmitz M, Niehoff A, Miosge N, Smyth N, Paulsson M, Zaucke F (2008). Transgenic mice expressing D469Delta mutated cartilage oligomeric matrix protein (COMP) show growth plate abnormalities and sternal malformations. Matrix Biol. Mar;27(2):67-85. Epub 2007 Aug 24

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Alvaro Rada-Iglesias

  • Draminski M, Rada-Iglesias A, Enroth S, Wadelius C, Koronacki J, Komorowski J (2008). Monte Carlo feature selection for supervised classification. Bioinformatics. Jan 1;24(1):110-7
  • Rada-Iglesias A, Ameur A, Kapranov P, Enroth S, Komorowski J, Gingeras TR, Wadelius C (2008). Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders. Genome Research. Mar;18(3):380-92
  • Respuela P, Ferella M, Rada-Iglesias A, Åslund L (2008). Histone acetylation at bidirectional promoters of divergent polycistronic gene clusters in Trypanosoma cruzi. J Biol Chem. Jun 6;283(23):15884-92

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H. Christian Reinhardt

  • Janes KA, Reinhardt HC, Yaffe MB (2008). Cytokine-induced signaling networks prioritize dynamic range over signal strength. Cell. Oct 17;135(2):343-54

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Elena I. Rugarli

  • Mancuso G, Rugarli EI (2008). A cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform. BMC Biol. Jul 9;6:31
  • Martignoni M, Riano E, Rugarli EI (2008). The role of ZFYVE27/protrudin in hereditary spastic paraplegia. Am J Hum Genet. Jul;83(1):127-8; author reply 128-30

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Nirmal Robinson 

  • Robinson N, Kolter T, Rybniker J, Wolke M, Hartmann P, Plum G (2008). A Mycobacterial glycolipid inhibits phagosome maturation and subverts proinflammatory cytokines. Traffic. 9(11):1936-47
  • Rybniker J, Plum G, Robinson N, Small PL, Hartmann P (2008). Identification of three cytotoxic early proteins of mycobacteriophage L5 leading to growth inhibition in Mycobacterium smegmatis. Microbiology. 154 (Pt 8): 2304-14

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Markus Schubert

  • Freude S, Leeser U, Müller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Köhler C, Schröder H, Krone W, Brüning JC, Schubert M (2008). IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination. J Neurochem. Nov;107(4):907-17. Epub 2008 Sep 18
  • Lee W, Han H, Lotnyk A, Schubert MA, Senz S, Alexe M, Hesse D, Baik S, Gösele U (2008). Individually addressable epitaxial ferroelectric nanocapacitor arrays with near Tb inch-2 density. Nat Nanotechnol. Jul;3(7):402-7. Epub 2008 Jun 15
  • Panella B, Hönes K, Müller U, Trukhan N, Schubert M, Pütter H, Hirscher M (2008). Desorption studies of hydrogen in metal-organic frameworks. Angew Chem Int Ed Engl. 2008;47(11):2138-42
  • Schmitz B, Müller U, Trukhan N, Schubert M, Férey G, Hirscher M (2008). Heat of adsorption for hydrogen in microporous high-surface-area materials. Chemphyschem. Oct 24;9(15):2181-4

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Günter Schwarz

  • Bevers LE, Hagedoorn PL, Santamaria-Araujo JA, Magalon A, Hagen WR, Schwarz G (2008). Function of MoaB proteins in the biosynthesis of the molybdenum and tungsten cofactors. Biochemistry. Jan 22;47(3):949-56. Epub 2007 Dec 22
  • Fritschy JM, Harvey R, Schwarz G (2008). Gephyrin: Where do we stand, where do we go? Trends in Neuroscience. 31: 257-64
  • Smolinsky B, Eichler SA, Buchmeier S, Meier JC, Schwarz G (2008). Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis. J Biol Chem. Jun 20;283(25):17370-9. Epub 2008 Apr 14

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Philipp Steven

  • Steven P, Rupp J, Hüttmann G, Koop N, Lensing C, Laqua H, Gebert A (2008). Experimental induction and three-dimensional two-photon imaging of conjunctiva-associated lymphoid tissue. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1512-7

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Wilhelm Stoffel

  • Stoffel W, Holz B, Jenke B, Binczek E, Günter RH, Kiss C, Karakesisoglou I, Thevis M, Weber AA, Arnhold S, Addicks K (2008). Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. EMBO J. Sep 3;27(17):2281-92

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Peter Tessarz

  • Mogk A, Haslberger T, Tessarz P, Bukau B (2008). Common and specific mechanisms of AAA+ proteins involved in protein quality control. Biochem Soc Trans. 36, 120
  • Tessarz P, Mogk A, Bukau B (2008). Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation. Mol Microbiol. 68, 87–97

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Mathias Treier

  • Nogueiras R, López M, Lage R, Perez-Tilve D, Pfluger P, Mendieta-Zerón H, Sakkou M, Wiedmer P, Benoit SC, Datta R, Dong JZ, Culler M, Sleeman M, Vidal-Puig A, Horvath T, Treier M, Diéguez C, Tschöp MH (2008). Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability. Endocrinology. Jun;149(6):3009-15. Epub 2008 Feb 28
  • Uhlenhaut NH, Treier M (2008). Transcriptional regulators in kidney disease: gatekeepers of renal homeostasis. Trends Genet. Jul;24(7):361-71. Epub 2008 May 29. Review

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Aleksandra Trifunovic

  • Stewart JB, Freyer C, Elson JL, Wredenberg A, Cansu Z, Trifunovic A, Larsson NG (2008). Strong purifying selection in transmission of mammalian mitochondrial DNA. PLoS Biol. Jan;6(1):e10

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Clemens Wendtner

  • Elter T, Molnar I, Kuhlmann J, Hallek M, Wendtner C (2008). Pharmacokinetics of alemtuzumab and the relevance in clinical practice. Leuk Lymphoma. Dec;49(12):2256-62. Review

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Sara Wickström

  • Wang HV, Chang LW, Brixius K, Wickström SA, Montanez E, Thievessen I, Schwander M, Müller U, Bloch W, Mayer U, Fässler R (2008). Integrin-linked kinase stabilizes myotendinous junctions and protects muscle from stress-induced damage. J Cell Biol. 180, 1037-1049
  • Zanivan S, Gnad F, Wickström SA, Geiger T, Macek B, Cox J, Fässler R, Mann M (2008). Solid Tumor Proteome and Phosphoproteome Analysis by High Resolution Mass Spectrometry. J Proteome Res. 7, 5314–5326

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Rudolf J. Wiesner

  • Franko A, Mayer S, Thiel G, Mercy L, Arnould T, Hornig-Do HT, Wiesner RJ, Goffart S (2008). CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation. Mol Cell Biol. Apr;28(7):2446-59. Epub 2008 Jan 28
  • Kornblum C, Zsurka G, Wiesner RJ, Schröder R, Kunz WS (2008). Concerted action of two novel tRNA mtDNA point mutations in chronic progressive external ophthalmoplegia. Biosci Rep. Apr;28(2):89-96

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Andreas Wodarz

  • Wodarz A (2008). Extraction and immunoblotting of proteins from embryos. Methods in Molekular Biology. Volume 420 Drosophila, Humana Press, Christian Dahmann (editor), 335-345

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Bernd Wollnik

  • Boulouiz R, Li Y, Soualhine H, Abidi O, Chafik A, Nürnberg G, Becker C, Nürnberg P, Kubisch C, Wollnik B, Barakat A (2008). A novel mutation in the Espin gene causes autosomal recessive nonsyndromic hearing loss but no apparent vestibular dysfunction in a Moroccan family. Am J Med Genet A. Dec 1;146A(23):3086-9
  • Budde BS, Namavar Y, Barth PG, Poll-The BT, Nürnberg G, Becker C, van Ruissen F, Weterman MA, Fluiter K, te Beek ET, Aronica E, van der Knaap MS, Höhne W, Toliat MR, Crow YJ, Steinling M, Voit T, Roelenso F, Brussel W, Brockmann K, Kyllerman M, Boltshauser E, Hammersen G, Willemsen M, Basel-Vanagaite L, Krägeloh-Mann I, de Vries LS, Sztriha L, Muntoni F, Ferrie CD, Battini R, Hennekam RC, Grillo E, Beemer FA, Stoets LM, Wollnik B, Nürnberg P, Baas F (2008). tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia. Nat Genet. Sep;40(9):1113-8
  • Collin RW, Kalay E, Tariq M, Peters T, van der Zwaag B, Venselaar H, Oostrik J, Lee K, Ahmed ZM, Caylan R, Li Y, Spierenburg HA, Eyupoglu E, Heister A, Riazuddin S, Bahat E, Ansar M, Arslan S, Wollnik B, Brunner HG, Cremers CW, Karaguzel A, Ahmad W, Cremers FP, Vriend G, Friedman TB, Riazuddin S, Leal SM, Kremer H (2008). Mutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35. Am J Hum Genet. Jan;82(1):125-38
  • Hasdemir C, Aydin HH, Sahin S, Wollnik B (2008). Catecholaminergic polymorphic ventricular tachycardia caused by a novel mutation in the cardiac ryanodine receptor. Anadolu Kardiyol Derg. Oct 16;8(5):E35-6

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Thomas Wunderlich

  • Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC (2008). PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response. Cell Metab. Apr;7(4):291-301
  • Frommer F, Heinen TJ, Wunderlich FT, Yogev N, Buch T, Roers A, Bettelli E, Müller W, Anderton SM, Waisman A (2008). Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion. J Immunol. Oct 15;181(8):5748-59
  • Klöting N, Koch L, Wunderlich FT, Kern M, Ruschke K, Krone W, Brüning JC, Blüher M (2008). Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth. Diabetes. Aug;57(8):2074-82. Epub 2008 Apr 28
  • Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC (2008). Central insulin action regulates peripheral glucose and fat metabolism in mice. J Clin Invest. Jun;118(6):2132-47
  • Merkwirth C, Dargazanli S, Tatsuta T, Geimer S, Löwer B, Wunderlich FT, von Kleist-Retzow JC, Waisman A, Westermann B, Langer T (2008). Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev. Feb 15;22(4):476-88
  • Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC (2008). Activation of Stat3 signaling in AgRP neurons promotes locomotor activity. Cell Metab. Mar;7(3):236-48
  • Stachelscheid H, Ibrahim H, Koch L, Schmitz A, Tscharntke M, Wunderlich FT, Scott J, Michels C, Wickenhauser C, Haase I, Brüning JC, Niessen CM (2008). Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation. EMBO J. Aug 6;27(15):2091-101. Epub 2008 Jul 24
  • Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC (2008). Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis. Proc Natl Acad Sci U S A. Jan 29;105(4):1297-302. Epub 2008 Jan 23

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